Mitochondrial dysfunction and endoplasmic reticulum stress in the promotion of fibrosis in obstructive nephropathy induced by unilateral ureteral obstruction

Microvesicles and exosomes in metabolic diseases and inflammation

(2020) L. Dini et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Sirtuin 3 Activation by Honokiol Decreases Unilateral Ureteral Obstruction-Induced Renal Inflammation and Fibrosis via Regulation of Mitochondrial Dynamics and the Renal NF-κB-TGF-β1/Smad Signaling Pathway

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Interaction of calcium binding protein S100A16 with myosin-9 promotes cytoskeleton reorganization in renal tubulointerstitial fibrosis

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Drp1-mediated mitochondrial fission promotes renal fibroblast activation and fibrogenesis

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The Role of Reactive Oxygen Species in the Life Cycle of the Mitochondrion

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Chronic impairment of mitochondrial bioenergetics and β-oxidation promotes experimental AKI-to-CKD transition induced by folic acid

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Fasting reduces oxidative stress, mitochondrial dysfunction and fibrosis induced by renal ischemia-reperfusion injury

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Saturated fatty acid stimulates production of extracellular vesicles by renal tubular epithelial cells

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FABP4 contributes to renal interstitial fibrosis via mediating inflammation and lipid metabolism

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Role of Autophagy on Heavy Metal-Induced Renal Damage and the Protective Effects of Curcumin in Autophagy and Kidney Preservation

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The contralateral kidney presents with impaired mitochondrial functions and disrupted redox homeostasis after 14 days of unilateral ureteral obstruction in mice

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Unilateral Ureteral Obstruction as a Model to Investigate Fibrosis-Attenuating Treatments

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MiR‐9‐5p protects from kidney fibrosis by metabolic reprogramming

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Drp1-regulated PARK2-dependent mitophagy protects against renal fibrosis in unilateral ureteral obstruction

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PDE/cAMP/Epac/C/EBP-β Signaling Cascade Regulates Mitochondria Biogenesis of Tubular Epithelial Cells in Renal Fibrosis

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Ablation of C/EBP homologous protein attenuates renal fibrosis after ureteral obstruction by reducing autophagy and microtubule disruption

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Renalase contributes to protection against renal fibrosis via inhibiting oxidative stress in rats

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Apoptosis-Associated Speck-Like Protein Containing a CARD Deletion Ameliorates Unilateral Ureteral Obstruction Induced Renal Fibrosis and Endoplasmic Reticulum Stress in Mice

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Mitochondrial dysfunction in diabetic kidney disease

(2018) Josephine M. Forbes et al.   Nature Reviews Nephrology

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Mitochondrial bioenergetics, redox state, dynamics and turnover alterations in renal mass reduction models of chronic kidney diseases and their possible implications in the progression of this illness

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Calcium Dynamics as a Machine for Decoding Signals

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Curcumin prevents potassium dichromate (K2Cr2O7)-induced renal hypoxia

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SIRT3 Overexpression Inhibits Growth of Kidney Tumor Cells and Enhances Mitochondrial Biogenesis

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Protective effects of N-acetyl-cysteine in mitochondria bioenergetics, oxidative stress, dynamics and S-glutathionylation alterations in acute kidney damage induced by folic acid

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Role of mitochondrial dysfunction in renal fibrosis promoted by hypochlorite-modified albumin in a remnant kidney model and protective effects of antioxidant peptide SS-31

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Curcumin prevents cisplatin-induced renal alterations in mitochondrial bioenergetics and dynamic

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Hydrogen sulfide-producing cystathionine γ-lyase is critical in the progression of kidney fibrosis

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Renalase Protects against Renal Fibrosis by Inhibiting the Activation of the ERK Signaling Pathways

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β-Aminoisobutyric acid ameliorates the renal fibrosis in mouse obstructed kidneys via inhibition of renal fibroblast activation and fibrosis

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Impaired β -Oxidation and Altered Complex Lipid Fatty Acid Partitioning with Advancing CKD

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Pharmacologic Approaches to Improve Mitochondrial Function in AKI and CKD

(2017) Hazel H. Szeto   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Intracellular Ca 2+ Sensing: Its Role in Calcium Homeostasis and Signaling

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Mitochondrial energetics in the kidney

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CD36 in chronic kidney disease: novel insights and therapeutic opportunities

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The mitochondria-targeted antioxidant MitoQ ameliorated tubular injury mediated by mitophagy in diabetic kidney disease via Nrf2/PINK1

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Mass Spectrometry Imaging of Kidney Tissue Sections of Rat Subjected to Unilateral Ureteral Obstruction

(2017) Huihui Liu et al.   Scientific Reports

Exosomes derived from palmitic acid-treated hepatocytes induce fibrotic activation of hepatic stellate cells

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N-acetylcysteine alleviates angiotensin II-mediated renal fibrosis in mouse obstructed kidneys

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Oxidative Stress and the Kidney: Riding on the Curve of Hormesis

(2016) Michael S. Goligorsky   ANTIOXIDANTS & REDOX SIGNALING

Persistent activation of autophagy in kidney tubular cells promotes renal interstitial fibrosis during unilateral ureteral obstruction

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Curcumin prevents mitochondrial dynamics disturbances in early 5/6 nephrectomy: Relation to oxidative stress and mitochondrial bioenergetics

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The nephroprotection exerted by curcumin in maleate-induced renal damage is associated with decreased mitochondrial fission and autophagy

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The Role of Mitochondria in Diabetic Kidney Disease

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Apocynin attenuates renal fibrosis via inhibition of NOXs-ROS-ERK-myofibroblast accumulation in UUO rats

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Blockade of Orai1 Store-Operated Calcium Entry Protects against Renal Fibrosis

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Protection of mitochondria prevents high-fat diet–induced glomerulopathy and proximal tubular injury

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The inflammatory cytokine TWEAK decreases PGC-1α expression and mitochondrial function in acute kidney injury

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Antagonism of scavenger receptor CD36 by 5A peptide prevents chronic kidney disease progression in mice independent of blood pressure regulation

(2016) Ana Carolina P. Souza et al.   KIDNEY INTERNATIONAL

Regulation of eIF2α expression and renal interstitial fibrosis by resveratrol in rat renal tissue after unilateral ureteral obstruction

(2016) Cui Zhang et al.   RENAL FAILURE

Calcium at the Center of Cell Signaling: Interplay between Endoplasmic Reticulum, Mitochondria, and Lysosomes

(2016) Anna Raffaello et al.   TRENDS IN BIOCHEMICAL SCIENCES

Endoplasmic reticulum stress drives proteinuria-induced kidney lesions via Lipocalin 2

(2016) Khalil El Karoui et al.   Nature Communications

Chemical chaperon 4-phenylbutyrate protects against the endoplasmic reticulum stress-mediated renal fibrosis in vivo and in vitro

(2016) Shing-Hwa Liu et al.   Oncotarget

Mitochondrial reactive oxygen species-mediated NLRP3 inflammasome activation contributes to aldosterone-induced renal tubular cells injury

(2016) Wei Ding et al.   Oncotarget

Protein S-glutathionlyation links energy metabolism to redox signaling in mitochondria

(2016) Ryan J. Mailloux et al.   Redox Biology

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The Macrophage Phagocytic Receptor CD36 Promotes Fibrogenic Pathways on Removal of Apoptotic Cells during Chronic Kidney Injury

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(2015) Joachim Krebs et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

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(2015) Josep A. Villena   FEBS Journal

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(2015) Thomas M. Durcan et al.   GENES & DEVELOPMENT

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(2015) Marina Morigi et al.   JOURNAL OF CLINICAL INVESTIGATION

Mitochondria: a therapeutic target in acute kidney injury

(2015) Yu Ishimoto et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Ginsenoside-Rg1 inhibits endoplasmic reticulum stress-induced apoptosis after unilateral ureteral obstruction in rats

(2015) Sha-sha Li et al.   RENAL FAILURE

Chop deficiency prevents UUO-induced renal fibrosis by attenuating fibrotic signals originated from Hmgb1/TLR4/NFκB/IL-1β signaling

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(2015) XIAN-FENG ZHAO et al.   Experimental and Therapeutic Medicine

Inhibition of Mitochondrial Complex-1 Prevents the Downregulation of NKCC2 and ENaCα in Obstructive Kidney Disease

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(2015) Bo-Zong Shao et al.   Frontiers in Pharmacology

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Antagonistic Regulation of Parvalbumin Expression and Mitochondrial Calcium Handling Capacity in Renal Epithelial Cells

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Calcium trafficking integrates endoplasmic reticulum function with mitochondrial bioenergetics

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Kidney fibrosis is independent of the amount of ascorbic acid in mice with unilateral ureteral obstruction

(2014) H. Nishida et al.   FREE RADICAL RESEARCH

Sites of Superoxide and Hydrogen Peroxide Production by Muscle Mitochondria Assessedex Vivounder Conditions Mimicking Rest and Exercise

(2014) Renata L. S. Goncalves et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Curcumin Ameliorates Renal Fibrosis by Inhibiting Local Fibroblast Proliferation and Extracellular Matrix Deposition

(2014) Xiangjun Zhou et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Defective fatty acid oxidation in renal tubular epithelial cells has a key role in kidney fibrosis development

(2014) Hyun Mi Kang et al.   NATURE MEDICINE

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(2014) Mei Tran et al.   NEPHRON CLINICAL PRACTICE

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The ER mitochondria calcium cycle and ER stress response as therapeutic targets in amyotrophic lateral sclerosis

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What is the best way to measure renal fibrosis?: A pathologist’s perspective

(2014) Alton B. Farris et al.   Kidney International Supplements

Mitochondrial respiratory chain complex I is inactivated by NADPH oxidase Nox4

(2013) Rafał Kozieł et al.   BIOCHEMICAL JOURNAL

Modulation of mitochondrial glutathione status and cellular energetics in primary cultures of proximal tubular cells from remnant kidney of uninephrectomized rats

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Autophagy and apoptosis in tubular cells following unilateral ureteral obstruction are associated with mitochondrial oxidative stress

(2013) YANFANG XU et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

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(2013) Alvaro C. Ucero et al.   INTERNATIONAL UROLOGY AND NEPHROLOGY

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NADPH Oxidases, Reactive Oxygen Species, and the Kidney: Friend and Foe

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Amygdalin inhibits renal fibrosis in chronic kidney disease

(2013) JUNQI GUO et al.   Molecular Medicine Reports

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(2013) Valerie S LeBleu et al.   NATURE MEDICINE

Suppressed mitochondrial biogenesis in folic acid-induced acute kidney injury and early fibrosis

(2013) L. Jay Stallons et al.   TOXICOLOGY LETTERS

Mitochondrial impairment in the five-sixth nephrectomy model of chronic renal failure: proteomic approach

(2013) Larisa V Fedorova et al.   BMC Nephrology

Indoxyl sulfate, a uremic toxin, downregulates renal expression of Nrf2 through activation of NF-κB

(2013) Dilinaer Bolati et al.   BMC Nephrology

Alpha-Lipoic Acid Attenuates Renal Injury in Rats with Obstructive Nephropathy

(2013) Orawan Wongmekiat et al.   Biomed Research International

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(2013) Casey L. Quinlan et al.   Redox Biology

Redox regulation of mitochondrial function with emphasis on cysteine oxidation reactions

(2013) Ryan J. Mailloux et al.   Redox Biology

Mitochondrial dysfunction accounts for aldosterone-induced epithelial-to-mesenchymal transition of renal proximal tubular epithelial cells

(2012) Yanggang Yuan et al.   FREE RADICAL BIOLOGY AND MEDICINE

Native rates of superoxide production from multiple sites in isolated mitochondria measured using endogenous reporters

(2012) Casey L. Quinlan et al.   FREE RADICAL BIOLOGY AND MEDICINE

TGF- 1-Containing Exosomes from Injured Epithelial Cells Activate Fibroblasts to Initiate Tissue Regenerative Responses and Fibrosis

(2012) F. T. Borges et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Activating Nrf-2 Signaling Depresses Unilateral Ureteral Obstruction-Evoked Mitochondrial Stress-Related Autophagy, Apoptosis and Pyroptosis in Kidney

(2012) Shue Dong Chung et al.   PLoS One

MicroRNA-21 Promotes Fibrosis of the Kidney by Silencing Metabolic Pathways

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(2012) Gabriella Casalena et al.   SEMINARS IN NEPHROLOGY

Interaction between Mitochondria and the Endoplasmic Reticulum: Implications for the Pathogenesis of Type 2 Diabetes Mellitus

(2011) Jaechan Leem et al.   Experimental Diabetes Research

Increased ER-mitochondrial coupling promotes mitochondrial respiration and bioenergetics during early phases of ER stress

(2011) R. Bravo et al.   JOURNAL OF CELL SCIENCE

Mitochondrial Biogenesis in Kidney Disease

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Resveratrol Inhibits Renal Fibrosis in the Obstructed Kidney

(2010) Jinhua Li et al.   AMERICAN JOURNAL OF PATHOLOGY

Mitochondrial proton and electron leaks

(2010) Martin Jastroch et al.   Essays in Biochemistry

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Ca2+ transfer from the ER to mitochondria: When, how and why

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CD36 Regulates Oxidative Stress and Inflammation in Hypercholesterolemic CKD

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Ureteral obstruction as a model of renal interstitial fibrosis and obstructive nephropathy

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Comparison of the effects of l-carnitine and α-tocopherol on acute ureteral obstruction-induced renal oxidative imbalance and altered energy metabolism in rats

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