Resveratrol-loaded nanoparticles conjugated with kidney injury molecule-1 as a drug delivery system for potential use in chronic kidney disease

Atg5-mediated autophagy deficiency in proximal tubules promotes cell cycle G2/M arrest and renal fibrosis

(2016) Huiyan Li et al.   Autophagy

Resveratrol ameliorates LPS-induced acute lung injury via NLRP3 inflammasome modulation

(2016) Lei Jiang et al.   BIOMEDICINE & PHARMACOTHERAPY

Far-infrared promotes burn wound healing by suppressing NLRP3 inflammasome caused by enhanced autophagy

(2016) Hui-Wen Chiu et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

The NLRP3 inflammasome in kidney disease and autoimmunity

(2016) Holly L Hutton et al.   NEPHROLOGY

Sirt1 is essential for resveratrol enhancement of hypoxia-induced autophagy in the type 2 diabetic nephropathy rat

(2016) Liqun Ma et al.   PATHOLOGY RESEARCH AND PRACTICE

Suppression of NLRP3 Inflammasome Activation Ameliorates Chronic Kidney Disease-Induced Cardiac Fibrosis and Diastolic Dysfunction

(2016) Antoinette Bugyei-Twum et al.   Scientific Reports

Resveratrol nanoformulations: Challenges and opportunities

(2015) Natalie Summerlin et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Resveratrol inhibits NLRP3 inflammasome activation by preserving mitochondrial integrity and augmenting autophagy

(2015) Ya-Ping Chang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Inflammasomes: mechanism of action, role in disease and therapeutics

(2015) Haitao Guo et al.   NATURE MEDICINE

Novel targets of antifibrotic and anti-inflammatory treatment in CKD

(2014) Anne-Emilie Declèves et al.   Nature Reviews Nephrology

Anti-nephrolithic potential of resveratrol via inhibition of ROS, MCP-1, hyaluronan and osteopontin in vitro and in vivo

(2014) Sang Hyuk Hong et al.   Pharmacological Reports

Bioenergetic Dysfunction and Inflammation in Alzheimer’s Disease: A Possible Connection

(2014) Heather M. Wilkins et al.   Frontiers in Aging Neuroscience

Autophagic cell death induced by resveratrol depends on the Ca2+/AMPK/mTOR pathway in A549 cells

(2013) Jun Zhang et al.   BIOCHEMICAL PHARMACOLOGY

Canonical and non-canonical effects of the NLRP3 inflammasome in kidney inflammation and fibrosis

(2013) Georg Lorenz et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Resveratrol as a therapeutic agent for renal fibrosis induced by unilateral ureteral obstruction

(2013) Jin Liang et al.   RENAL FAILURE

Resveratrol in Medicinal Chemistry: A Critical Review of its Pharmacokinetics, Drug-Delivery, and Membrane Interactions

(2012) A. R. Neves et al.   CURRENT MEDICINAL CHEMISTRY

Resveratrol prevents renal lipotoxicity and inhibits mesangial cell glucotoxicity in a manner dependent on the AMPK–SIRT1–PGC1α axis in db/db mice

(2012) M. Y. Kim et al.   DIABETOLOGIA

Resveratrol Nanoparticle System Improves Dissolution Properties and Enhances the Hepatoprotective Effect of Resveratrol through Antioxidant and Anti-Inflammatory Pathways

(2012) Chiang-Wen Lee et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Activation of autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destruction

(2012) Chong-Shan Shi et al.   NATURE IMMUNOLOGY

Multifunctional hybrid silica nanoparticles for controlled doxorubicin loading and release with thermal and pH dual response

(2012) Xixue Hu et al.   Journal of Materials Chemistry B

Chronic Inflammation Links Cardiovascular, Metabolic and Renal Diseases

(2011) Ichiro Manabe   CIRCULATION JOURNAL

mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice

(2011) Ken Inoki et al.   JOURNAL OF CLINICAL INVESTIGATION

The Inflammasomes in Kidney Disease

(2011) H.-J. Anders et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Resveratrol improves renal microcirculation, protects the tubular epithelium, and prolongs survival in a mouse model of sepsis-induced acute kidney injury

(2011) Joseph H. Holthoff et al.   KIDNEY INTERNATIONAL

Monitoring of inflammation in patients on dialysis: forewarned is forearmed

(2011) Christiaan L. Meuwese et al.   Nature Reviews Nephrology

Tubulointerstitial injury and the progression of chronic kidney disease

(2011) Kavita S. Hodgkins et al.   PEDIATRIC NEPHROLOGY

Pivotal Role of Toll-Like Receptors 2 and 4, Its Adaptor Molecule MyD88, and Inflammasome Complex in Experimental Tubule-Interstitial Nephritis

(2011) Matheus Correa-Costa et al.   PLoS One

Resveratrol Attenuates Renal Hypertrophy in Early-Stage Diabetes by Activating AMPK

(2010) Da-Fa Ding et al.   AMERICAN JOURNAL OF NEPHROLOGY

Resveratrol Inhibits Renal Fibrosis in the Obstructed Kidney

(2010) Jinhua Li et al.   AMERICAN JOURNAL OF PATHOLOGY

Combination treatment with arsenic trioxide and irradiation enhances cell-killing effects in human fibrosarcoma cells in vitro and in vivo through induction of both autophagy and apoptosis

(2010) Hui-Wen Chiu et al.   Autophagy

The Inflammasomes

(2010) Kate Schroder et al.   CELL

The NLRP3 Inflammasome Promotes Renal Inflammation and Contributes to CKD

(2010) A. Vilaysane et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Cutting Edge: NF- B Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression

(2009) F. G. Bauernfeind et al.   JOURNAL OF IMMUNOLOGY

Cancer chemopreventive and therapeutic potential of resveratrol: Mechanistic perspectives

(2008) Joydeb Kumar Kundu et al.   CANCER LETTERS

Kidney injury molecule–1 is a phosphatidylserine receptor that confers a phagocytic phenotype on epithelial cells

(2008) Takaharu Ichimura et al.   JOURNAL OF CLINICAL INVESTIGATION