Honokiol Attenuates Sepsis-Associated Acute Kidney Injury via the Inhibition of Oxidative Stress and Inflammation

Honokiol protects against renal ischemia/reperfusion injury via the suppression of oxidative stress, iNOS, inflammation and STAT3 in rats

(2015) YONGWU YU et al.   Molecular Medicine Reports

Saikosaponin A protects against experimental sepsis via inhibition of NOD2-mediated NF-κB activation

(2015) HAIYAN ZHAO et al.   Experimental and Therapeutic Medicine

Effects of Honokiol on Sepsis-Induced Acute Kidney Injury in an Experimental Model of Sepsis in Rats

(2014) Nan Li et al.   INFLAMMATION

Proteomic Analysis of Ubiquitin Ligase KEAP1 Reveals Associated Proteins That Inhibit NRF2 Ubiquitination

(2013) B. E. Hast et al.   CANCER RESEARCH

Bilirubin mediated oxidative stress involves antioxidant response activation via Nrf2 pathway

(2013) Mohammed Qaisiya et al.   CELLULAR SIGNALLING

Therapeutic targeting of the mitochondrial dysfunction in septic acute kidney injury

(2013) Samir M. Parikh   Current Opinion in Critical Care

Myeloperoxidase: Expressing Inflammation and Oxidative Stress in Cardiovascular Disease

(2013) Nikolaos Anatoliotakis et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

A tetrahydroisoquinoline alkaloid THI-28 reduces LPS-induced HMGB1 and diminishes organ injury in septic mice through p38 and PI3K/Nrf2/HO-1 signals

(2013) Hee Sook Kim et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Frequent concerted genetic mechanisms disrupt multiple components of the NRF2 inhibitor KEAP1/CUL3/RBX1 E3-ubiquitin ligase complex in thyroid cancer

(2013) Victor D Martinez et al.   Molecular Cancer

Resveratrol Alleviates Endotoxin-Induced Myocardial Toxicity via the Nrf2 Transcription Factor

(2013) Enkui Hao et al.   PLoS One

Noncanonical Nuclear Factor Kappa B (NF-κB) Signaling and Potential for Therapeutics in Sepsis

(2013) Simone Thair et al.   Current Infectious Disease Reports

A novel small molecule, HK-156, inhibits lipopolysaccharide-induced activation of NF-κB signaling and improves survival in mouse models of sepsis

(2012) Jian-ping Fang et al.   ACTA PHARMACOLOGICA SINICA

Ursolic acid promotes the neuroprotection by activating Nrf2 pathway after cerebral ischemia in mice

(2012) Litao Li et al.   BRAIN RESEARCH

Honokiol protects brain against ischemia–reperfusion injury in rats through disrupting PSD95–nNOS interaction

(2012) Zhenyu Hu et al.   BRAIN RESEARCH

NF-κB-mediated inverse regulation of fractalkine and CX3CR1 during CLP-induced sepsis

(2012) C. Raspé et al.   CYTOKINE

A sepse como causa de lesão renal aguda: modelo experimental

(2012) Carolina Ferreira Pinto et al.   Revista da Escola de Enfermagem da USP

Honokiol protects rat hearts against myocardial ischemia reperfusion injury by reducing oxidative stress and inflammation

(2012) YUN WANG et al.   Experimental and Therapeutic Medicine

Enhancing Nrf2 Pathway by Disruption of Keap1 in Myeloid Leukocytes Protects against Sepsis

(2011) Xiaoni Kong et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Honokiol rescues sepsis-associated acute lung injury and lethality via the inhibition of oxidative stress and inflammation

(2011) Te I. Weng et al.   INTENSIVE CARE MEDICINE

Endotoxin Uptake by S1 Proximal Tubular Segment Causes Oxidative Stress in the Downstream S2 Segment

(2011) R. Kalakeche et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Sepsis as a cause and consequence of acute kidney injury: Program to Improve Care in Acute Renal Disease

(2010) Ravindra L. Mehta et al.   INTENSIVE CARE MEDICINE

The role of advanced oxidation protein products in intensive care unit patients with acute kidney injury

(2010) Paolo Lentini et al.   JOURNAL OF CRITICAL CARE

NADPH Oxidase-Dependent Reactive Oxygen Species Mediate Amplified TLR4 Signaling and Sepsis-Induced Mortality in Nrf2-Deficient Mice

(2010) X. Kong et al.   JOURNAL OF IMMUNOLOGY

SEPSIS, LEUKOCYTES, AND NITRIC OXIDE (NO)

(2010) Carl F. Fortin et al.   SHOCK

THE ROLE OF INNATE IMMUNITY IN SEPTIC ACUTE KIDNEY INJURIES

(2010) Giselle Martins Gonçalves et al.   SHOCK

Anti-inflammatory effect of honokiol is mediated by PI3K/Akt pathway suppression

(2009) Byung Hun Kim et al.   ACTA PHARMACOLOGICA SINICA

Animal models of sepsis and sepsis-induced kidney injury

(2009) Kent Doi et al.   JOURNAL OF CLINICAL INVESTIGATION

Ginkgo biloba extract confers protection from cigarette smoke extract-induced apoptosis in human lung endothelial cells: Role of heme oxygenase-1

(2009) Chiu-Ling Hsu et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

NF-κB and P38 MAPK Inhibition Improve Survival in Endotoxin Shock and in a Cecal Ligation and Puncture Model of Sepsis in Combination With Antibiotic Therapy

(2008) Adrian W. O'Sullivan et al.   JOURNAL OF SURGICAL RESEARCH