- Home
- Publications
- Publication Search
- Publication Details
Title
Inflammasomes and Pyroptosis of Liver Cells in Liver Fibrosis
Authors
Keywords
-
Journal
Frontiers in Immunology
Volume 13, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2022-05-30
DOI
10.3389/fimmu.2022.896473
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Role of Immune Cells in Biliary Repair
- (2022) Tian Lan et al. Frontiers in Immunology
- Cell death pathways: intricate connections and disease implications
- (2021) Matthias Kist et al. EMBO JOURNAL
- Role of necroptosis in chronic hepatic inflammation and fibrosis in a mouse model of increased oxidative stress
- (2021) Sabira Mohammed et al. FREE RADICAL BIOLOGY AND MEDICINE
- Psoralidin, a major component of Psoraleae Fructus, induces inflammasome activation and idiosyncratic liver injury
- (2021) Yan Wang et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Ginseng Saponin Enriched in Rh1 and Rg2 Ameliorates Nonalcoholic Fatty Liver Disease by Inhibiting Inflammasome Activation
- (2021) Feng Wang et al. Nutrients
- TGR5 Regulates Macrophage Inflammation in Nonalcoholic Steatohepatitis by Modulating NLRP3 Inflammasome Activation
- (2021) Yong Shi et al. Frontiers in Immunology
- Mitochondrial DNA enables AIM2 inflammasome activation and hepatocyte pyroptosis in non-alcoholic fatty liver disease
- (2021) Lu Xu et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Celecoxib ameliorates liver cirrhosis via reducing inflammation and oxidative stress along spleen-liver axis in rats
- (2021) Shihang Tang et al. LIFE SCIENCES
- Regulation and functional roles of chemokines in liver diseases
- (2021) Sheng Cao et al. Nature Reviews Gastroenterology & Hepatology
- Perfluoroalkyl substance pollutants activate the innate immune system through the AIM2 inflammasome
- (2021) Li-Qiu Wang et al. Nature Communications
- Caspase-11–Mediated Hepatocytic Pyroptosis Promotes the Progression of Nonalcoholic Steatohepatitis
- (2021) Yingwei Zhu et al. Cellular and Molecular Gastroenterology and Hepatology
- Myeloid Nrf2 deficiency aggravates non-alcoholic steatohepatitis progression by regulating YAP-mediated NLRP3 inflammasome signaling
- (2021) Peng Wang et al. iScience
- Circular RNA as An Epigenetic Regulator in Chronic Liver Diseases
- (2021) Xianhui Zeng et al. Cells
- Celecoxib reduces hepatic vascular resistance in portal hypertension by amelioration of endothelial oxidative stress
- (2021) Yang Tai et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Mechanism and Therapeutic Opportunities of Histone Modifications in Chronic Liver Disease
- (2021) Qiuyu Cai et al. Frontiers in Pharmacology
- MCC950 Ameliorates Acute Liver Injury Through Modulating Macrophage Polarization and Myeloid-Derived Suppressor Cells Function
- (2021) Wei Yan et al. Frontiers in Medicine
- Purine signaling regulating HSCs inflammatory cytokines secretion, activation, and proliferation plays a critical role in alcoholic liver disease
- (2020) Liang Shan et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Brucella abortus Infection Elicited Hepatic Stellate Cell-Mediated Fibrosis Through Inflammasome-Dependent IL-1β Production
- (2020) Paula Constanza Arriola Benitez et al. Frontiers in Immunology
- Toward targeting inflammasomes: insights into their regulation and activation
- (2020) Shelbi Christgen et al. CELL RESEARCH
- Hepatic stellate cell autophagy inhibits extracellular vesicle release to attenuate liver fibrosis
- (2020) Jinhang Gao et al. JOURNAL OF HEPATOLOGY
- NLRP3 inflammasome and related cytokines reflect the immune status of patients with HBV-ACLF
- (2020) Yanhong Jia et al. MOLECULAR IMMUNOLOGY
- Calcipotriol Inhibits NLRP3 Signal Through YAP1 Activation to Alleviate Cholestatic Liver Injury and Fibrosis
- (2020) Xiaopeng Wang et al. Frontiers in Pharmacology
- NLRP6 Plays an Important Role in Early Hepatic Immunopathology Caused by Schistosoma mansoni Infection
- (2020) Rodrigo C. O. Sanches et al. Frontiers in Immunology
- Palmitic acid stimulates NLRP3 inflammasome activation through TLR4-NF-κB signal pathway in hepatic stellate cells
- (2020) Zhixia Dong et al. Annals of Translational Medicine
- Bidirectional role of NLRP3 during acute and chronic cholestatic liver injury
- (2020) Mick Frissen et al. HEPATOLOGY
- Hepatocyte pyroptosis and release of inflammasome particles induce stellate cell activation and liver fibrosis
- (2020) Susanne Gaul et al. JOURNAL OF HEPATOLOGY
- Pharmacological inhibition of P2RX7 ameliorates liver injury by reducing inflammation and fibrosis
- (2020) Bernat Baeza-Raja et al. PLoS One
- Celecoxib attenuates hepatocyte apoptosis by inhibiting endoplasmic reticulum stress in thioacetamide-induced cirrhotic rats
- (2020) Wei Su et al. WORLD JOURNAL OF GASTROENTEROLOGY
- RIP1 kinase activity promotes steatohepatitis through mediating cell death and inflammation in macrophages
- (2020) Liang Tao et al. CELL DEATH AND DIFFERENTIATION
- Sphingomyelin synthase 1 mediates hepatocyte pyroptosis to trigger non-alcoholic steatohepatitis
- (2020) Eun Hee Koh et al. GUT
- NKT cells promote both type 1 and type 2 inflammatory responses in a mouse model of liver fibrosis
- (2020) Julia Nilsson et al. Scientific Reports
- Endothelial p300 Promotes Portal Hypertension and Hepatic Fibrosis Through C‐C Motif Chemokine Ligand 2–Mediated Angiocrine Signaling
- (2020) Jinhang Gao et al. HEPATOLOGY
- NLRP3 inflammasome activation from Kupffer cells is involved in liver fibrosis of Schistosoma japonicum-infected mice via NF-κB
- (2019) Wen-Juan Zhang et al. Parasites & Vectors
- Modulation of calcium signaling pathway by hepatitis C virus core protein stimulates NLRP3 inflammasome activation
- (2019) Amina A. Negash et al. PLoS Pathogens
- Impaired mitophagy triggers NLRP3 inflammasome activation during the progression from nonalcoholic fatty liver to nonalcoholic steatohepatitis
- (2019) Ning-Ping Zhang et al. LABORATORY INVESTIGATION
- Activated NK cells kill hepatic stellate cells via p38/PI3K signaling in a TRAIL‐involved degranulation manner
- (2019) Tianyang Li et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Decreased Macrophage Autophagy Promotes Liver Injury and Inflammation from Alcohol
- (2019) Ghulam Ilyas et al. ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH
- NLRC4 inflammasome activation regulated by TNF-α promotes inflammatory responses in nonalcoholic fatty liver disease
- (2019) Yihe Chen et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Liver organoids: from basic research to therapeutic applications
- (2019) Nicole Prior et al. GUT
- Tim-4 Inhibits NLRP3 Inflammasome via the LKB1/AMPKα Pathway in Macrophages
- (2019) Wen Liu et al. JOURNAL OF IMMUNOLOGY
- Pathobiology of inherited biliary diseases: a roadmap to understand acquired liver diseases
- (2019) Luca Fabris et al. Nature Reviews Gastroenterology & Hepatology
- Macrophage Polarization: Different Gene Signatures in M1(LPS+) vs. Classically and M2(LPS–) vs. Alternatively Activated Macrophages
- (2019) Marco Orecchioni et al. Frontiers in Immunology
- Tyrosine Dephosphorylation of ASC Modulates the Activation of the NLRP3 and AIM2 Inflammasomes
- (2019) Bezaleel Mambwe et al. Frontiers in Immunology
- The Pyrin Inflammasome in Health and Disease
- (2019) Oskar Schnappauf et al. Frontiers in Immunology
- Liraglutide ameliorates non-alcoholic steatohepatitis by inhibiting NLRP3 inflammasome and pyroptosis activation via mitophagy
- (2019) Xinyang Yu et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Role of aldosterone in the activation of primary mice hepatic stellate cell and liver fibrosis via NLRP3 inflammasome
- (2019) Yang Li et al. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
- Spliceosome-Associated Protein 130 Exacerbates Alcohol-Induced Liver Injury by Inducing NLRP3 Inflammasome–Mediated IL-1β in Mice
- (2018) Jong-Won Kim et al. AMERICAN JOURNAL OF PATHOLOGY
- Inhibition of IL-18 reduces renal fibrosis after ischemia-reperfusion
- (2018) Hua Liang et al. BIOMEDICINE & PHARMACOTHERAPY
- Mechanism of membrane pore formation by human gasdermin‐D
- (2018) Estefania Mulvihill et al. EMBO JOURNAL
- Alcohol dysregulates miR-148a in hepatocytes through FoxO1, facilitating pyroptosis via TXNIP overexpression
- (2018) Mi Jeong Heo et al. GUT
- Pyroptosis by caspase11/4-gasdermin-D pathway in alcoholic hepatitis in mice and patients
- (2018) Elena Khanova et al. HEPATOLOGY
- Bax inhibitor-1 protects from nonalcoholic steatohepatitis by limiting inositol-requiring enzyme 1 alpha signaling in mice
- (2018) Cynthia Lebeaupin et al. HEPATOLOGY
- Leucodin attenuates inflammatory response in macrophages and lipid accumulation in steatotic hepatocytes via P2x7 receptor pathway: A potential role in alcoholic liver disease
- (2018) Yue Shang et al. BIOMEDICINE & PHARMACOTHERAPY
- AIM2 deficiency reduces the development of hepatocellular carcinoma in mice
- (2018) Claudia Martínez-Cardona et al. INTERNATIONAL JOURNAL OF CANCER
- Liver fibrosis: Pathophysiology, pathogenetic targets and clinical issues
- (2018) Maurizio Parola et al. MOLECULAR ASPECTS OF MEDICINE
- FXR Inhibits Endoplasmic Reticulum Stress-Induced NLRP3 Inflammasome in Hepatocytes and Ameliorates Liver Injury
- (2018) Chang Yeob Han et al. Cell Reports
- Inflammasome: A Double-Edged Sword in Liver Diseases
- (2018) Jingyun Luan et al. Frontiers in Immunology
- The role of macrophages in nonalcoholic fatty liver disease and nonalcoholic steatohepatitis
- (2018) Konstantin Kazankov et al. Nature Reviews Gastroenterology & Hepatology
- Hepatitis C virus-induced CCL5 secretion from macrophages activates hepatic stellate cells
- (2017) Reina Sasaki et al. HEPATOLOGY
- Liver inflammation and fibrosis
- (2017) Yukinori Koyama et al. JOURNAL OF CLINICAL INVESTIGATION
- Targeting hepatic macrophages to treat liver diseases
- (2017) Frank Tacke JOURNAL OF HEPATOLOGY
- Role of the inflammasome in acetaminophen-induced liver injury and acute liver failure
- (2017) Benjamin L. Woolbright et al. JOURNAL OF HEPATOLOGY
- NLRP3 inflammasome blockade reduces liver inflammation and fibrosis in experimental NASH in mice
- (2017) Auvro R. Mridha et al. JOURNAL OF HEPATOLOGY
- Dietary PUFAs attenuate NLRP3 inflammasome activation via enhancing macrophage autophagy
- (2017) Lulu Shen et al. JOURNAL OF LIPID RESEARCH
- Palmitic acid elicits hepatic stellate cell activation through inflammasomes and hedgehog signaling
- (2017) Na-Na Duan et al. LIFE SCIENCES
- Mechanisms of hepatic stellate cell activation
- (2017) Takuma Tsuchida et al. Nature Reviews Gastroenterology & Hepatology
- Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease
- (2017) Paul M Ridker et al. NEW ENGLAND JOURNAL OF MEDICINE
- Deficiency of the Purinergic Receptor 2X7 Attenuates Nonalcoholic Steatohepatitis Induced by High-Fat Diet: Possible Role of the NLRP3 Inflammasome
- (2017) Claudia Blasetti Fantauzzi et al. Oxidative Medicine and Cellular Longevity
- Clinical Trial Design for Alcoholic Hepatitis
- (2017) Gyongyi Szabo SEMINARS IN LIVER DISEASE
- NAIP/NLRC4 inflammasome activation in MRP8+ cells is sufficient to cause systemic inflammatory disease
- (2017) Randilea D. Nichols et al. Nature Communications
- NLRP3 inflammasome activation results in liver inflammation and fibrosis in mice infected with Schistosoma japonicum in a Syk-dependent manner
- (2017) Ya-Qi Lu et al. Scientific Reports
- Celecoxib and octreotide synergistically ameliorate portal hypertension via inhibition of angiogenesis in cirrhotic rats
- (2016) Jin-Hang Gao et al. ANGIOGENESIS
- Angiotensin-(1–7) Improves Liver Fibrosis by Regulating the NLRP3 Inflammasome via Redox Balance Modulation
- (2016) Shuang-Ming Cai et al. ANTIOXIDANTS & REDOX SIGNALING
- Inflammasome Complexes: Emerging Mechanisms and Effector Functions
- (2016) Vijay A.K. Rathinam et al. CELL
- Intrahepatic NK cells function suppressed in advanced liver fibrosis
- (2016) Xiaoyan Li et al. EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
- NLRP12 negatively regulates proinflammatory cytokine production and host defense against Brucella abortus
- (2016) Tatiana N. Silveira et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Galectin-3 regulates inflammasome activation in cholestatic liver injury
- (2016) Jijing Tian et al. FASEB JOURNAL
- Redox-dependent regulation of hepatocyte absent in melanoma 2 inflammasome activation in sterile liver injury in mice
- (2016) Qian Sun et al. HEPATOLOGY
- Intervention with a caspase-1 inhibitor reduces obesity-associated hyperinsulinemia, non-alcoholic steatohepatitis and hepatic fibrosis in LDLR−/−.Leiden mice
- (2016) M C Morrison et al. INTERNATIONAL JOURNAL OF OBESITY
- Uric acid regulates hepatic steatosis and insulin resistance through the NLRP3 inflammasome-dependent mechanism
- (2016) Xingyong Wan et al. JOURNAL OF HEPATOLOGY
- Sinusoidal communication in liver fibrosis and regeneration
- (2016) Giusi Marrone et al. JOURNAL OF HEPATOLOGY
- Characterization of the Inflammasome in Human Kupffer Cells in Response to Synthetic Agonists and Pathogens
- (2016) Claudia Zannetti et al. JOURNAL OF IMMUNOLOGY
- Reactive Oxygen Species-Induced TXNIP Drives Fructose-Mediated Hepatic Inflammation and Lipid Accumulation Through NLRP3 Inflammasome Activation
- (2015) Xian Zhang et al. ANTIOXIDANTS & REDOX SIGNALING
- Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion
- (2015) Wan-ting He et al. CELL RESEARCH
- Caspase-11 activates a canonical NLRP3 inflammasome by promoting K+efflux
- (2015) Sebastian Rühl et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Tetramethylpyrazine reduces inflammation in liver fibrosis and inhibits inflammatory cytokine expression in hepatic stellate cells by modulating NLRP3 inflammasome pathway
- (2015) Xiafei Wu et al. IUBMB LIFE
- Caspase-8 as an Effector and Regulator of NLRP3 Inflammasome Signaling
- (2015) Christina Antonopoulos et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Absent in melanoma 2 triggers a heightened inflammasome response in ascitic fluid macrophages of patients with cirrhosis
- (2015) Beatriz Lozano-Ruiz et al. JOURNAL OF HEPATOLOGY
- Metabolic danger signals, uric acid and ATP, mediate inflammatory cross-talk between hepatocytes and immune cells in alcoholic liver disease
- (2015) Jan Petrasek et al. JOURNAL OF LEUKOCYTE BIOLOGY
- The Cholangiopathies
- (2015) Konstantinos N. Lazaridis et al. MAYO CLINIC PROCEEDINGS
- Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling
- (2015) Nobuhiko Kayagaki et al. NATURE
- Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
- (2015) Jianjin Shi et al. NATURE
- Inflammasome activation and function in liver disease
- (2015) Gyongyi Szabo et al. Nature Reviews Gastroenterology & Hepatology
- Mechanisms of inflammasome activation: recent advances and novel insights
- (2015) Sivapriya K. Vanaja et al. TRENDS IN CELL BIOLOGY
- ER stress induces NLRP3 inflammasome activation and hepatocyte death
- (2015) C Lebeaupin et al. Cell Death & Disease
- Monocytes Activate Natural Killer Cells via Inflammasome-Induced Interleukin 18 in Response to Hepatitis C Virus Replication
- (2014) Elisavet Serti et al. GASTROENTEROLOGY
- Cyclooxygenase-2 Regulates NLRP3 Inflammasome-Derived IL-1β Production
- (2014) Kuo-Feng Hua et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Cholesterol-lowering drugs cause dissolution of cholesterol crystals and disperse Kupffer cell crown-like structures during resolution of NASH
- (2014) George N. Ioannou et al. JOURNAL OF LIPID RESEARCH
- The pan-caspase inhibitor Emricasan (IDN-6556) decreases liver injury and fibrosis in a murine model of non-alcoholic steatohepatitis
- (2014) Fernando J. Barreyro et al. LIVER INTERNATIONAL
- Molecular Basis for Specific Recognition of Bacterial Ligands by NAIP/NLRC4 Inflammasomes
- (2014) Jeannette L. Tenthorey et al. MOLECULAR CELL
- Flavonoid Apigenin Inhibits Lipopolysaccharide-Induced Inflammatory Response through Multiple Mechanisms in Macrophages
- (2014) Xiaoxuan Zhang et al. PLoS One
- Therapeutic potential of interleukin 1 inhibitors in the treatment of alcoholic liver disease
- (2013) Stephanie Mathews et al. HEPATOLOGY
- NLRP3 inflammasome activation results in hepatocyte pyroptosis, liver inflammation, and fibrosis in mice
- (2013) Alexander Wree et al. HEPATOLOGY
- IL-1β Production through the NLRP3 Inflammasome by Hepatic Macrophages Links Hepatitis C Virus Infection with Liver Inflammation and Disease
- (2013) Amina A. Negash et al. PLoS Pathogens
- Toll-like receptor 2 and palmitic acid cooperatively contribute to the development of nonalcoholic steatohepatitis through inflammasome activation in mice
- (2012) Kouichi Miura et al. HEPATOLOGY
- Autolytic Proteolysis within the Function to Find Domain (FIIND) Is Required for NLRP1 Inflammasome Activity
- (2012) Joshua N. Finger et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- IL-1 receptor antagonist ameliorates inflammasome-dependent alcoholic steatohepatitis in mice
- (2012) Jan Petrasek et al. JOURNAL OF CLINICAL INVESTIGATION
- Inflammasomes in liver diseases
- (2012) Gyongyi Szabo et al. JOURNAL OF HEPATOLOGY
- Inflammasomes in health and disease
- (2012) Till Strowig et al. NATURE
- Rapid induction of inflammatory lipid mediators by the inflammasome in vivo
- (2012) Jakob von Moltke et al. NATURE
- Differential Ly-6C expression identifies the recruited macrophage phenotype, which orchestrates the regression of murine liver fibrosis
- (2012) P. Ramachandran et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Anthrax and the inflammasome
- (2011) Mahtab Moayeri et al. MICROBES AND INFECTION
- A role for mitochondria in NLRP3 inflammasome activation
- (2010) Rongbin Zhou et al. NATURE
- The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses
- (2010) Vijay A K Rathinam et al. NATURE IMMUNOLOGY
- IL-1 pathways in inflammation and human diseases
- (2010) Cem Gabay et al. Nature Reviews Rheumatology
- Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome
- (2010) E. A. Miao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Inflammasome-mediated regulation of hepatic stellate cells
- (2009) Azuma Watanabe et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Pan-caspase inhibitor VX-166 reduces fibrosis in an animal model of nonalcoholic steatohepatitis
- (2009) Rafal P. Witek et al. HEPATOLOGY
- Cutting Edge: NF- B Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression
- (2009) F. G. Bauernfeind et al. JOURNAL OF IMMUNOLOGY
- Neisseria gonorrhoeae Activates the Proteinase Cathepsin B to Mediate the Signaling Activities of the NLRP3 and ASC-Containing Inflammasome
- (2009) Joseph A. Duncan et al. JOURNAL OF IMMUNOLOGY
- AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC
- (2009) Veit Hornung et al. NATURE
- The NALP3 inflammasome is involved in the innate immune response to amyloid-β
- (2008) Annett Halle et al. NATURE IMMUNOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation