Pyroptosis by caspase11/4-gasdermin-D pathway in alcoholic hepatitis in mice and patients

Lipidomics reveals dramatic lipid compositional changes in the maturing postnatal lung

(2017) Sydney E. Dautel et al.   Scientific Reports

A Mechanistic Review of Cell Death in Alcohol-Induced Liver Injury

(2016) Shaogui Wang et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Intestinal REG3 Lectins Protect against Alcoholic Steatohepatitis by Reducing Mucosa-Associated Microbiota and Preventing Bacterial Translocation

(2016) Lirui Wang et al.   Cell Host & Microbe

Alcoholic hepatitis: Translational approaches to develop targeted therapies

(2016) Pranoti Mandrekar et al.   HEPATOLOGY

Pathogenesis of alcoholic liver disease

(2016) Kazushi Sugimoto et al.   HEPATOLOGY RESEARCH

Pore-forming activity and structural autoinhibition of the gasdermin family

(2016) Jingjin Ding et al.   NATURE

Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores

(2016) Xing Liu et al.   NATURE

LPS-TLR4 Pathway Mediates Ductular Cell Expansion in Alcoholic Hepatitis

(2016) Gemma Odena et al.   Scientific Reports

Supplementation of Saturated Long-Chain Fatty Acids Maintains Intestinal Eubiosis and Reduces Ethanol-induced Liver Injury in Mice

(2015) Peng Chen et al.   GASTROENTEROLOGY

Fat-Specific Protein 27/CIDEC Promotes Development of Alcoholic Steatohepatitis in Mice and Humans

(2015) Ming-Jiang Xu et al.   GASTROENTEROLOGY

Pyroptotic cell death defends against intracellular pathogens

(2015) Ine Jorgensen et al.   IMMUNOLOGICAL REVIEWS

Creating reference gene annotation for the mouse C57BL6/J genome assembly

(2015) Jonathan M. Mudge et al.   MAMMALIAN GENOME

Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling

(2015) Nobuhiko Kayagaki et al.   NATURE

Liver Fibrosis in Alcoholic Liver Disease

(2015) Bin Gao et al.   SEMINARS IN LIVER DISEASE

A Histologic Scoring System for Prognosis of Patients With Alcoholic Hepatitis

(2014) José Altamirano et al.   GASTROENTEROLOGY

Osteopontin deficiency does not prevent but promotes alcoholic neutrophilic hepatitis in mice

(2014) Raul Lazaro et al.   HEPATOLOGY

Mouse model of chronic and binge ethanol feeding (the NIAAA model)

(2013) Adeline Bertola et al.   Nature Protocols

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

(2013) Daehwan Kim et al.   GENOME BIOLOGY

Transcriptome analysis identifies TNF superfamily receptors as potential therapeutic targets in alcoholic hepatitis

(2012) Silvia Affò et al.   GUT

Liver progenitor cell markers correlate with liver damage and predict short-term mortality in patients with alcoholic hepatitis

(2012) Pau Sancho-Bru et al.   HEPATOLOGY

Absence of receptor interacting protein kinase 3 prevents ethanol-induced liver injury

(2012) Sanjoy Roychowdhury et al.   HEPATOLOGY

IL-1 receptor antagonist ameliorates inflammasome-dependent alcoholic steatohepatitis in mice

(2012) Jan Petrasek et al.   JOURNAL OF CLINICAL INVESTIGATION

Mouse intragastric infusion (iG) model

(2012) Akiko Ueno et al.   Nature Protocols

Alcoholic Liver Disease: Pathogenesis and New Therapeutic Targets

(2011) Bin Gao et al.   GASTROENTEROLOGY

Global quantification of mammalian gene expression control

(2011) Björn Schwanhäusser et al.   NATURE

Early Liver Transplantation for Severe Alcoholic Hepatitis

(2011) Philippe Mathurin et al.   NEW ENGLAND JOURNAL OF MEDICINE

Evaluation of statistical methods for normalization and differential expression in mRNA-Seq experiments

(2010) James H Bullard et al.   BMC BIOINFORMATICS

Th17 cells and their associated cytokines in liver diseases

(2010) Fouad Lafdil et al.   Cellular & Molecular Immunology

Enteric dysbiosis associated with a mouse model of alcoholic liver disease

(2010) Arthur W. Yan et al.   HEPATOLOGY

Alcoholic Hepatitis

(2009) Michael R. Lucey et al.   NEW ENGLAND JOURNAL OF MEDICINE