Flavonoid Apigenin Inhibits Lipopolysaccharide-Induced Inflammatory Response through Multiple Mechanisms in Macrophages

Plant Flavone Apigenin Binds to Nucleic Acid Bases and Reduces Oxidative DNA Damage in Prostate Epithelial Cells

(2014) Haripaul Sharma et al.   PLoS One

Natural products: A continuing source of novel drug leads

(2013) Gordon M. Cragg et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Advancing Drug Discovery and Development from Active Constituents of Yinchenhao Tang, a Famous Traditional Chinese Medicine Formula

(2013) Aihua Zhang et al.   Evidence-based Complementary and Alternative Medicine

Apigenin Protects Endothelial Cells from Lipopolysaccharide (LPS)-Induced Inflammation by Decreasing Caspase-3 Activation and Modulating Mitochondrial Function

(2013) Silvia Duarte et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Flavonoid apigenin modified gene expression associated with inflammation and cancer and induced apoptosis in human pancreatic cancer cells through inhibition of GSK-3β/NF-κB signaling cascade

(2013) Jodee L. Johnson et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Novel Insights into the Pharmacology of Flavonoids

(2013) Barbara Romano et al.   PHYTOTHERAPY RESEARCH

Ethanol Inhibits Activation of NLRP3 and AIM2 Inflammasomes in Human Macrophages–A Novel Anti-Inflammatory Action of Alcohol

(2013) Katariina Nurmi et al.   PLoS One

NLRP3 activation induces ASC-dependent programmed necrotic cell death, which leads to neutrophilic inflammation

(2013) T Satoh et al.   Cell Death & Disease

Flavonoids and Asthma

(2013) Toshio Tanaka et al.   Nutrients

Flavonoids and metabolic syndrome

(2012) Monica Galleano et al.   Annals of the New York Academy of Sciences

Flavonoids in Cancer Prevention

(2012) Eun-Jung Park et al.   Anti-Cancer Agents in Medicinal Chemistry

The application of Chinese medicine to novel drug discovery

(2012) Nikolaus J Sucher   Expert Opinion on Drug Discovery

Flavonoids in the therapy and prophylaxis of flu: a patent review

(2012) Sônia S Costa et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

A review of the dietary flavonoid, kaempferol on human health and cancer chemoprevention

(2012) Allen Y. Chen et al.   FOOD CHEMISTRY

The effects of dietary flavonoids on the regulation of redox inflammatory networks

(2012) Valerio Izzi   Frontiers in Bioscience-Landmark

Apigenin Inhibits the Expression of IL-6, IL-8, and ICAM-1 in DEHP-Stimulated Human Umbilical Vein Endothelial Cells and In Vivo

(2012) Jia Wang et al.   INFLAMMATION

The Anti-Tumorigenic Mushroom Agaricus blazei Murill Enhances IL-1β Production and Activates the NLRP3 Inflammasome in Human Macrophages

(2012) Tsung-Teng Huang et al.   PLoS One

The NLRP3 inflammasome in health and disease: the good, the bad and the ugly

(2011) P. Menu et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Effects of Flavonoids and other Polyphenols on Inflammation

(2011) R. González et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Histamine H4 receptor activation enhances LPS-induced IL-6 production in mast cells via ERK and PI3K activation

(2011) Pragnya Desai et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The açaí flavonoid velutin is a potent anti-inflammatory agent: blockade of LPS-mediated TNF-α and IL-6 production through inhibiting NF-κB activation and MAPK pathway

(2011) Chenghui Xie et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

NLRP3 inflammasomes link inflammation and metabolic disease

(2011) Dominic De Nardo et al.   TRENDS IN IMMUNOLOGY

Lavandulyl Flavonoids from Sophora flavescens Suppress Lipopolysaccharide-Induced Activation of Nuclear Factor-κB and Mitogen-Activated Protein Kinases in RAW264.7 Cells

(2010) Jong-Min Han et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

The Inflammasomes

(2010) Kate Schroder et al.   CELL

Control of Macrophage Activation and Function by PPARs

(2010) Ajay Chawla   CIRCULATION RESEARCH

Apigenin inhibits allergen-induced airway inflammation and switches immune response in a murine model of asthma

(2010) Ruo-Ran Li et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

Apigenin: A Promising Molecule for Cancer Prevention

(2010) Sanjeev Shukla et al.   PHARMACEUTICAL RESEARCH

Targeting Inflammatory Pathways by Flavonoids for Prevention and Treatment of Cancer

(2010) Sahdeo Prasad et al.   PLANTA MEDICA

Berberine Inhibits HIV Protease Inhibitor-Induced Inflammatory Response by Modulating ER Stress Signaling Pathways in Murine Macrophages

(2010) Weibin Zha et al.   PLoS One

Flavonoids as anti-inflammatory agents

(2010) Mauro Serafini et al.   PROCEEDINGS OF THE NUTRITION SOCIETY

Immunological and Inflammatory Functions of the Interleukin-1 Family

(2009) Charles A. Dinarello   Annual Review of Immunology

HIV protease inhibitor lopinavir-induced TNF-α and IL-6 expression is coupled to the unfolded protein response and ERK signaling pathways in macrophages

(2009) Li Chen et al.   BIOCHEMICAL PHARMACOLOGY

Impact of Natural Products on Developing New Anti-Cancer Agents†

(2009) Gordon M. Cragg et al.   CHEMICAL REVIEWS

Flavonoids as anti-inflammatory agents: implications in cancer and cardiovascular disease

(2009) Ana García-Lafuente et al.   INFLAMMATION RESEARCH

The Caspase-1 Inflammasome: A Pilot of Innate Immune Responses

(2008) Hong Bing Yu et al.   Cell Host & Microbe

A natural history of botanical therapeutics

(2008) Barbara Schmidt et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Inflammation

(2008) Ursula Weiss   NATURE

Nuclear factor-κB1: Regulation and function

(2007) Silvia Gaspar Pereira et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY