Pharmacogenetics and Precision Medicine Approaches for the Improvement of COVID-19 Therapies
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Title
Pharmacogenetics and Precision Medicine Approaches for the Improvement of COVID-19 Therapies
Authors
Keywords
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Journal
Frontiers in Pharmacology
Volume 13, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2022-02-18
DOI
10.3389/fphar.2022.835136
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Note: Only part of the references are listed.- Effects of the CYP2C19 LoF allele on major adverse cardiovascular events associated with clopidogrel in acute coronary syndrome patients undergoing percutaneous coronary intervention: a meta-analysis
- (2022) Mohitosh Biswas et al. PHARMACOGENOMICS
- Anatomical and Pathological Observation and Analysis of SARS and COVID-19: Microthrombosis Is the Main Cause of Death
- (2021) Wenjing Chen et al. BIOLOGICAL PROCEDURES ONLINE
- Current Updates on Naturally Occurring Compounds Recognizing SARS-CoV-2 Druggable Targets
- (2021) Isabella Romeo et al. MOLECULES
- A prospective, observational study to evaluate adverse drug reactions in patients with COVID-19 treated with remdesivir or hydroxychloroquine: a preliminary report
- (2021) Fátima Falcão et al. European Journal of Hospital Pharmacy-Science and Practice
- Screening of potent drug inhibitors against SARS-CoV-2 RNA polymerase: an in silico approach
- (2021) Sanjay Kumar Singh et al. 3 Biotech
- Interactions of Potential Anti-COVID-19 Compounds with Multispecific ABC and OATP Drug Transporters
- (2021) Ágnes Telbisz et al. Pharmaceutics
- In silico Screening of Natural Compounds as Potential Inhibitors of SARS-CoV-2 Main Protease and Spike RBD: Targets for COVID-19
- (2021) Divya M. Teli et al. Frontiers in Molecular Biosciences
- Drug‐drug interactions with candidate medications used for COVID‐19 treatment: An overview
- (2021) Haleh Rezaee et al. Pharmacology Research & Perspectives
- Association of CYP2C19 Loss-of-Function Alleles with Major Adverse Cardiovascular Events of Clopidogrel in Stable Coronary Artery Disease Patients Undergoing Percutaneous Coronary Intervention: Meta-analysis
- (2021) Mohitosh Biswas et al. CARDIOVASCULAR DRUGS AND THERAPY
- The Hydroalcoholic Extract of Uncaria tomentosa (Cat’s Claw) Inhibits the Infection of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) In Vitro
- (2021) Andres F. Yepes-Perez et al. Evidence-based Complementary and Alternative Medicine
- Promising phytochemicals of traditional Indian herbal steam inhalation therapy to combat COVID-19 – An in silico study
- (2021) Shanmugaraj Gowrishankar et al. FOOD AND CHEMICAL TOXICOLOGY
- Inhibition of drug-metabolizing enzymes by Qingfei Paidu decoction: Implication of herb-drug interactions in COVID-19 pharmacotherapy
- (2021) Feng Zhang et al. FOOD AND CHEMICAL TOXICOLOGY
- An in-silico approach to identify the potential hot spots in SARS-CoV-2 spike RBD to block the interaction with ACE2 receptor
- (2021) Antony Stalin et al. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
- Receptor-Based Pharmacophore Modeling in the Search for Natural Products for Covid-19 Mpro
- (2021) Mohd Saeed et al. MOLECULES
- COVID-19: Auswirkungen auf Lunge und Herz
- (2021) Maximilian Ackermann et al. PATHOLOGE
- Pharmacogenomics and COVID-19: clinical implications of human genome interactions with repurposed drugs
- (2021) Osama A. Badary PHARMACOGENOMICS JOURNAL
- Structure of the SARS-CoV-2 RNA-dependent RNA polymerase in the presence of favipiravir-RTP
- (2021) Katerina Naydenova et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pharmacogenetics Approach for the Improvement of COVID-19 Treatment
- (2021) Ingrid Fricke-Galindo et al. Viruses-Basel
- Association of angiotensin-converting enzyme inhibitors and angiotensin-receptor blockers with risk of mortality, severity or SARS-CoV-2 test positivity in COVID-19 patients: meta-analysis
- (2021) Mohitosh Biswas et al. Scientific Reports
- Severe covid-19 pneumonia: pathogenesis and clinical management
- (2021) Amy H Attaway et al. BMJ-British Medical Journal
- Screening of inhibitors against SARS-CoV-2 spike protein and their capability to block the viral entry mechanism: A viroinformatics study
- (2021) Abd-ElAziem Farouk et al. SAUDI JOURNAL OF BIOLOGICAL SCIENCES
- Essential oils as an effective alternative for the treatment of COVID-19: Molecular interaction analysis of protease (Mpro) with pharmacokinetics and toxicological properties
- (2021) Sukanya Panikar et al. Journal of Infection and Public Health
- Corilagin inhibits SARS-CoV-2 replication by targeting viral RNA-dependent RNA polymerase
- (2021) Quanjie Li et al. Acta Pharmaceutica Sinica B
- Evaluation of potential anti-RNA-dependent RNA polymerase (RdRP) drugs against the newly emerged model of COVID-19 RdRP using computational methods
- (2021) Alireza Poustforoosh et al. BIOPHYSICAL CHEMISTRY
- Discovery of potent Covid‐19 main protease inhibitors using integrated drug‐repurposing strategy
- (2021) Muthu Kumar T et al. BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY
- Pharmacogenomics research and its clinical implementation in Thailand: Lessons learned from the resource-limited settings
- (2021) Chonlaphat Sukasem et al. Drug Metabolism and Pharmacokinetics
- SARS-CoV-2 Papain-Like Protease Potential Inhibitors—In Silico Quantitative Assessment
- (2021) Adam Stasiulewicz et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Molnupiravir promotes SARS-CoV-2 mutagenesis via the RNA template
- (2021) Calvin J. Gordon et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Potentiality of Moringa oleifera against SARS-CoV-2: identified by a rational computer aided drug design method
- (2021) Debanjan Sen et al. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
- Association between the HLA genotype and the severity of COVID‐19 infection among South Asians
- (2021) Fatmah M. A. Naemi et al. JOURNAL OF MEDICAL VIROLOGY
- Identification of phytocompounds from Houttuynia cordata Thunb. as potential inhibitors for SARS-CoV-2 replication proteins through GC–MS/LC–MS characterization, molecular docking and molecular dynamics simulation
- (2021) Sanjib Kumar Das et al. MOLECULAR DIVERSITY
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- (2021) Mohammad Hassan Baig et al. MOLECULES
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- (2021) Marie Scully et al. NEW ENGLAND JOURNAL OF MEDICINE
- Thrombosis and Thrombocytopenia after ChAdOx1 nCoV-19 Vaccination
- (2021) Nina H. Schultz et al. NEW ENGLAND JOURNAL OF MEDICINE
- Predictive association of ABCB1 C3435T genetic polymorphism with the efficacy or safety of lopinavir and ritonavir in COVID-19 patients
- (2021) Mohitosh Biswas PHARMACOGENOMICS
- Scutellaria barbata D. Don Inhibits the Main Proteases (Mpro and TMPRSS2) of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection
- (2021) Sheng-Teng Huang et al. Viruses-Basel
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- (2021) Khushboo Bafna et al. Cell Reports
- Inhaled budesonide in the treatment of early COVID-19 (STOIC): a phase 2, open-label, randomised controlled trial
- (2021) Sanjay Ramakrishnan et al. Lancet Respiratory Medicine
- Virtual Screening and Molecular Docking Studies for Discovery of Potential RNA-Dependent RNA Polymerase Inhibitors
- (2021) Mohammed Y. Ghazwani et al. Crystals
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- (2021) David J. Langton et al. HLA
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- (2021) Osvaldo Yañez et al. BIOMEDICINE & PHARMACOTHERAPY
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- Pharmacogenomics and Vaccine Development
- (2021) Gregory A. Poland et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
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- (2021) Sarah Jafrin et al. European Journal of Internal Medicine
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- (2021) Thawinee Jantararoungtong et al. Expert Opinion on Drug Metabolism & Toxicology
- Efficacy and safety of remdesivir in hospitalised COVID-19 patients: a systematic review and meta-analysis
- (2021) Mulugeta T. Angamo et al. INFECTION
- Variants in ACE2; potential influences on virus infection and COVID-19 severity
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- Potential clinically significant drug‐drug interactions of hydroxychloroquine used in the treatment of COVID‐19
- (2021) Mohitosh Biswas et al. INTERNATIONAL JOURNAL OF CLINICAL PRACTICE
- Geraniin Inhibits the Entry of SARS-CoV-2 by Blocking the Interaction between Spike Protein RBD and Human ACE2 Receptor
- (2021) Young Soo Kim et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Exploring the Binding Mechanism of PF-07321332 SARS-CoV-2 Protease Inhibitor through Molecular Dynamics and Binding Free Energy Simulations
- (2021) Bilal Ahmad et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Molecular dynamics simulation, 3D-pharmacophore and scaffold hopping analysis in the design of multi-target drugs to inhibit potential targets of COVID-19
- (2021) Neda Fayyazi et al. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
- Screening of potential bio-molecules from Moringa olifera against SARS-CoV-2 main protease using computational approaches
- (2021) Shalini Mathpal et al. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
- Pharmacophore Model for SARS-CoV-2 3CLpro Small-Molecule Inhibitors and in Vitro Experimental Validation of Computationally Screened Inhibitors
- (2021) Enrico Glaab et al. Journal of Chemical Information and Modeling
- GC-MS, LC-MS/MS, Docking and Molecular Dynamics Approaches to Identify Potential SARS-CoV-2 3-Chymotrypsin-Like Protease Inhibitors from Zingiber officinale Roscoe
- (2021) Muhammad Sulaiman Zubair et al. MOLECULES
- Identification of SARS-CoV-2 Receptor Binding Inhibitors by In Vitro Screening of Drug Libraries
- (2021) Alon Ben David et al. MOLECULES
- Mechanism of molnupiravir-induced SARS-CoV-2 mutagenesis
- (2021) Florian Kabinger et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Pharmacogenomic considerations for repurposing of dexamethasone as a potential drug against SARS-CoV-2 infection
- (2021) Manik Vohra et al. Personalized Medicine
- Spectrum of cutaneous adverse reactions to aromatic antiepileptic drugs and human leukocyte antigen genotypes in Thai patients and meta-analysis
- (2021) Chonlaphat Sukasem et al. PHARMACOGENOMICS JOURNAL
- Hesperidin Is a Potential Inhibitor against SARS-CoV-2 Infection
- (2021) Fang-Ju Cheng et al. Nutrients
- Allele frequencies of single nucleotide polymorphisms of clinically important drug-metabolizing enzymes CYP2C9, CYP2C19, and CYP3A4 in a Thai population
- (2021) Rattanaporn Sukprasong et al. Scientific Reports
- Combining SARS-CoV-2 Proofreading Exonuclease and RNA-Dependent RNA Polymerase Inhibitors as a Strategy to Combat COVID-19: A High-Throughput in silico Screening
- (2021) Shradha Khater et al. Frontiers in Microbiology
- Identification of SARS-CoV-2 inhibitors from extracts of Houttuynia cordata Thunb
- (2021) Arun Bahadur Gurung et al. SAUDI JOURNAL OF BIOLOGICAL SCIENCES
- Identification of SARS‐CoV‐2 Main Protease Inhibitors Using Structure Based Virtual Screening and Molecular Dynamics Simulation of DrugBank Database
- (2021) Pradip Debnath et al. ChemistrySelect
- Can Antiviral Activity of Licorice Help Fight COVID-19 Infection?
- (2021) Luisa Diomede et al. Biomolecules
- Strawberry and Ginger Silver Nanoparticles as Potential Inhibitors for SARS-CoV-2 Assisted by In Silico Modeling and Metabolic Profiling
- (2021) Mohammad M. Al-Sanea et al. Antibiotics-Basel
- TPMT*3C as a Predictor of 6-Mercaptopurine-Induced Myelotoxicity in Thai Children with Acute Lymphoblastic Leukemia
- (2021) Thawinee Jantararoungtong et al. Journal of Personalized Medicine
- A Narrative Review of the Clinical Practicalities of Bamlanivimab and Etesevimab Antibody Therapies for SARS-CoV-2
- (2021) Ramesh Nathan et al. Infectious Diseases and Therapy
- ADME and Pharmacokinetic Properties of Remdesivir: Its Drug Interaction Potential
- (2021) Subrata Deb et al. Pharmaceuticals
- Reynoutria Rhizomes as a Natural Source of SARS-CoV-2 Mpro Inhibitors–Molecular Docking and In Vitro Study
- (2021) Izabela Nawrot-Hadzik et al. Pharmaceuticals
- Angiotensin-Converting Enzyme 2 (ACE2) in the Context of Respiratory Diseases and Its Importance in Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection
- (2021) Enrique Ambrocio-Ortiz et al. Pharmaceuticals
- Molnupiravir for Oral Treatment of Covid-19 in Nonhospitalized Patients
- (2021) Angélica Jayk Bernal et al. NEW ENGLAND JOURNAL OF MEDICINE
- Endogenous Antibody Responses to SARS-CoV-2 in Patients With Mild or Moderate COVID-19 Who Received Bamlanivimab Alone or Bamlanivimab and Etesevimab Together
- (2021) Lin Zhang et al. Frontiers in Immunology
- Compounds with therapeutic potential against novel respiratory 2019 coronavirus
- (2020) Miguel Angel Martinez ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Mechanisms of homocysteine-induced damage to the endothelial, medial and adventitial layers of the arterial wall
- (2020) Brittany Balint et al. BIOCHIMIE
- Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro
- (2020) Manli Wang et al. CELL RESEARCH
- Review of the Clinical Characteristics of Coronavirus Disease 2019 (COVID-19)
- (2020) Fang Jiang et al. JOURNAL OF GENERAL INTERNAL MEDICINE
- Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study
- (2020) Nanshan Chen et al. LANCET
- Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
- (2020) Chaolin Huang et al. LANCET
- Anti-HCV, nucleotide inhibitors, repurposing against COVID-19
- (2020) Abdo A. Elfiky LIFE SCIENCES
- Mechanisms of action of hydroxychloroquine and chloroquine: implications for rheumatology
- (2020) Eva Schrezenmeier et al. Nature Reviews Rheumatology
- Genetic and clinical risk factors associated with phenytoin‐induced cutaneous adverse drug reactions in Thai population
- (2020) Chonlaphat Sukasem et al. PHARMACOEPIDEMIOLOGY AND DRUG SAFETY
- Association study of genetic polymorphisms in proteins involved in oseltamivir transport, metabolism, and interactions with adverse reactions in Mexican patients with acute respiratory diseases
- (2020) Mario Bermúdez de León et al. PHARMACOGENOMICS JOURNAL
- Clinical and biochemical indexes from 2019-nCoV infected patients linked to viral loads and lung injury
- (2020) Yingxia Liu et al. Science China-Life Sciences
- Genetic Diversity of HLA Class I and Class II Alleles in Thai Populations: Contribution to Genotype-Guided Therapeutics
- (2020) Patompong Satapornpong et al. Frontiers in Pharmacology
- Identification of antiviral drug candidates against SARS-CoV-2 from FDA-approved drugs
- (2020) Sangeun Jeon et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- The emergence of SARS, MERS and novel SARS-2 coronaviruses in the 21st century
- (2020) Vivaldo Gomes da Costa et al. ARCHIVES OF VIROLOGY
- Why Are Lopinavir and Ritonavir Effective against the Newly Emerged Coronavirus 2019? Atomistic Insights into the Inhibitory Mechanisms
- (2020) Bodee Nutho et al. BIOCHEMISTRY
- Structural and Functional Basis of SARS-CoV-2 Entry by Using Human ACE2
- (2020) Qihui Wang et al. CELL
- Angiotensin-Converting Enzyme 2: SARS-CoV-2 Receptor and Regulator of the Renin-Angiotensin System
- (2020) Mahmoud Gheblawi et al. CIRCULATION RESEARCH
- COVID-19: Coronavirus replication, pathogenesis, and therapeutic strategies
- (2020) Cornelia C. Bergmann et al. CLEVELAND CLINIC JOURNAL OF MEDICINE
- Clinical Pharmacogenetics Implementation Consortium Guideline (CPIC) for CYP2C9 and Nonsteroidal Anti‐Inflammatory Drugs
- (2020) Katherine N. Theken et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Risks of ACE Inhibitor and ARB Usage in COVID‐19: Evaluating the Evidence
- (2020) Krishna Sriram et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Genetic association of co‐trimoxazole‐induced severe cutaneous adverse reactions is phenotype‐specific: HLA class I genotypes and haplotypes
- (2020) Chonlaphat Sukasem et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Incidence of Adverse Drug Reactions in COVID‐19 Patients in China: An Active Monitoring Study by Hospital Pharmacovigilance System
- (2020) Ji Sun et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Favipiravir: Pharmacokinetics and Concerns About Clinical Trials for 2019‐nCoV Infection
- (2020) Yin‐Xiao Du et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- What do we know about remdesivir drug interactions?
- (2020) Katherine Yang CTS-Clinical and Translational Science
- Critical Assessment of Pharmacokinetic Drug–Drug Interaction Potential of Tofacitinib, Baricitinib and Upadacitinib, the Three Approved Janus Kinase Inhibitors for Rheumatoid Arthritis Treatment
- (2020) Vijayabhaskar Veeravalli et al. DRUG SAFETY
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- (2020) Yolanda Macías et al. Expert Opinion on Drug Metabolism & Toxicology
- SARS-CoV-2 Vaccines: Status Report
- (2020) Fatima Amanat et al. IMMUNITY
- Structural and molecular modelling studies reveal a new mechanism of action of chloroquine and hydroxychloroquine against SARS-CoV-2 infection
- (2020) Jacques Fantini et al. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
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- (2020) Chi Zhang et al. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
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- (2020) James M. Sanders et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
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- (2020) Sourav Das et al. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
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- (2020) Rakesh S. Joshi et al. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
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- (2020) Mark Tristan J. Quimque et al. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
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- (2020) Betsy J. Barnes et al. JOURNAL OF EXPERIMENTAL MEDICINE
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- (2020) Rui Shi et al. NATURE
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- (2020) Jun Lan et al. NATURE
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- (2020) Zhenming Jin et al. NATURE
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- (2020) Maximilian Ackermann et al. NEW ENGLAND JOURNAL OF MEDICINE
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- (2020) Bin Cao et al. NEW ENGLAND JOURNAL OF MEDICINE
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- (2020) Ke Hu et al. PHYTOMEDICINE
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- (2020) Linlin Zhang et al. SCIENCE
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- (2020) Wanchao Yin et al. SCIENCE
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- (2020) Bhupesh Goyal et al. ACS Combinatorial Science
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- (2020) Brendan T Freitas et al. ACS Infectious Diseases
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- (2020) Li Runfeng et al. PHARMACOLOGICAL RESEARCH
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- (2020) Mohitosh Biswas et al. PLATELETS
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- (2020) F.A. Klok et al. THROMBOSIS RESEARCH
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- (2020) Laura Rombolà et al. Life-Basel
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- (2020) Ranu Baral et al. Current Atherosclerosis Reports
- Mechanism and inhibition of the papain‐like protease, PLpro, of SARS‐CoV‐2
- (2020) Theresa Klemm et al. EMBO JOURNAL
- Fight against novel coronavirus: A perspective of medicinal chemists
- (2020) Sk Abdul Amin et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Increased risk of acute stroke among patients with severe COVID‐19: a multicenter study and meta‐analysis
- (2020) T. Siepmann et al. EUROPEAN JOURNAL OF NEUROLOGY
- Investigating Potential Inhibitory Effect of Uncaria tomentosa (Cat’s Claw) against the Main Protease 3CLpro of SARS-CoV-2 by Molecular Modeling
- (2020) Andres F. Yepes-Pérez et al. Evidence-based Complementary and Alternative Medicine
- Effects of the ABCB1 C3435T single nucleotide polymorphism on major adverse cardiovascular events in acute coronary syndrome or coronary artery disease patients undergoing percutaneous coronary intervention and treated with clopidogrel: A systematic review and meta-analysis
- (2020) Mohitosh Biswas et al. Expert Opinion On Drug Safety
- Targeting COVID-19 (SARS-CoV-2) main protease through active phytochemicals of ayurvedic medicinal plants – Withania somnifera (Ashwagandha), Tinospora cordifolia (Giloy) and Ocimum sanctum (Tulsi) – a molecular docking study
- (2020) Priya Shree et al. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
- Repurposing drugs for treatment of SARS-CoV-2 infection: computational design insights into mechanisms of action
- (2020) Shubhangi Kandwal et al. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
- The Use of Renin–Angiotensin–Aldosterone System (RAAS) Inhibitors is Associated with a Lower Risk of Mortality in Hypertensive COVID‐19 Patients: A Systematic Review and Meta‐analysis
- (2020) Yixuan Wang et al. JOURNAL OF MEDICAL VIROLOGY
- Homocysteine as a potential predictor of cardiovascular risk in patients with COVID-19
- (2020) Giovanni Ponti et al. MEDICAL HYPOTHESES
- Characteristics of SARS-CoV-2 and COVID-19
- (2020) Ben Hu et al. NATURE REVIEWS MICROBIOLOGY
- Serious Ivermectin Toxicity and Human ABCB1 Nonsense Mutations
- (2020) Eloise Baudou et al. NEW ENGLAND JOURNAL OF MEDICINE
- Global distribution of CYP2C19 risk phenotypes affecting safety and effectiveness of medications
- (2020) Mohitosh Biswas PHARMACOGENOMICS JOURNAL
- Therapeutic potential of resveratrol against emerging respiratory viral infections
- (2020) Simone Filardo et al. PHARMACOLOGY & THERAPEUTICS
- Revisiting pharmacological potentials of Nigella sativa seed: A promising option for COVID ‐19 prevention and cure
- (2020) Mohammad Nazrul Islam et al. PHYTOTHERAPY RESEARCH
- Pros and cons of corticosteroid therapy for COVID-19 patients
- (2020) Paula Mattos-Silva et al. RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
- Antiviral potential of garlic (Allium sativum) and its organosulfur compounds: A systematic update of pre-clinical and clinical data
- (2020) Razina Rouf et al. TRENDS IN FOOD SCIENCE & TECHNOLOGY
- HLA genetic polymorphisms and prognosis of patients with COVID-19
- (2020) L. Lorente et al. Medicina Intensiva
- D-dimer level in COVID-19 infection: a systematic review
- (2020) Mehrdad Rostami et al. Expert Review of Hematology
- Molecular interaction and inhibition of SARS-CoV-2 binding to the ACE2 receptor
- (2020) Jinsung Yang et al. Nature Communications
- A living WHO guideline on drugs for covid-19
- (2020) François Lamontagne et al. BMJ-British Medical Journal
- Genetic Hypothesis and Pharmacogenetics Side of Renin-Angiotensin-System in COVID-19
- (2020) Donato Gemmati et al. Genes
- Innate Immune Responses to Highly Pathogenic Coronaviruses and Other Significant Respiratory Viral Infections
- (2020) Hanaa Ahmed-Hassan et al. Frontiers in Immunology
- HLA allele frequencies and susceptibility to COVID ‐19 in a group of 99 Italian patients
- (2020) Antonio Novelli et al. HLA
- Antibody-dependent enhancement and SARS-CoV-2 vaccines and therapies
- (2020) Wen Shi Lee et al. Nature Microbiology
- Activity profiling and crystal structures of inhibitor-bound SARS-CoV-2 papain-like protease: A framework for anti–COVID-19 drug design
- (2020) Wioletta Rut et al. Science Advances
- Phenoconversion of Cytochrome P450 Metabolism: A Systematic Review
- (2020) Sylvia D. Klomp et al. Journal of Clinical Medicine
- Pharmacogenomics of COVID-19 therapies
- (2020) Takuto Takahashi et al. npj Genomic Medicine
- Pharmacogenomics and Pharmacogenetics: In Silico Prediction of Drug Effects in Treatments for Novel Coronavirus SARS-CoV2 Disease
- (2020) Concetta Cafiero et al. Pharmacogenomics & Personalized Medicine
- Uncovering Flexible Active Site Conformations of SARS-CoV-2 3CL Proteases through Protease Pharmacophore Clusters and COVID-19 Drug Repurposing
- (2020) Nikhil Pathak et al. ACS Nano
- Efficacy and safety of COVID-19 vaccines in older people
- (2020) Roy L Soiza et al. AGE AND AGEING
- Protease targeted COVID-19 drug discovery and its challenges: Insight into viral main protease (Mpro) and papain-like protease (PLpro) inhibitors
- (2020) Sk. Abdul Amin et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Treatment for COVID-19: An overview
- (2020) Cristina Stasi et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Association of Sex, Age, and Comorbidities with Mortality in COVID-19 Patients: A Systematic Review and Meta-Analysis
- (2020) Mohitosh Biswas et al. INTERVIROLOGY
- Anisotine and amarogentin as promising inhibitory candidates against SARS-CoV-2 proteins: a computational investigation
- (2020) Pallab Kar et al. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
- Antiretrovirals for Prophylaxis Against COVID‐19: A Comprehensive Literature Review
- (2020) Golbarg Alavian et al. JOURNAL OF CLINICAL PHARMACOLOGY
- Risk factors prediction, clinical outcomes, and mortality in COVID‐19 patients
- (2020) Roohallah Alizadehsani et al. JOURNAL OF MEDICAL VIROLOGY
- Molecular modelling investigation for drugs and nutraceuticals against protease of SARS-CoV-2
- (2020) Kanchanok Kodchakorn et al. JOURNAL OF MOLECULAR GRAPHICS & MODELLING
- Computational study on peptidomimetic inhibitors against SARS-CoV-2 main protease
- (2020) Tuanjai Somboon et al. JOURNAL OF MOLECULAR LIQUIDS
- Tocilizumab in Patients Hospitalized with Covid-19 Pneumonia
- (2020) Carlos Salama et al. NEW ENGLAND JOURNAL OF MEDICINE
- Analysis of the efficacy of HIV protease inhibitors against SARS-CoV-2′s main protease
- (2020) Mohamed Mahdi et al. Virology Journal
- In silico studies evidenced the role of structurally diverse plant secondary metabolites in reducing SARS-CoV-2 pathogenesis
- (2020) Hariprasad Puttaswamy et al. Scientific Reports
- Incidence of Suspected Serious Adverse Drug Reactions in Corona Virus Disease-19 Patients Detected by a Pharmacovigilance Program by Laboratory Signals in a Tertiary Hospital in Spain: Cautionary Data
- (2020) Elena Ramírez et al. Frontiers in Pharmacology
- Human Leukocyte Antigen Complex and Other Immunogenetic and Clinical Factors Influence Susceptibility or Protection to SARS-CoV-2 Infection and Severity of the Disease Course. The Sardinian Experience
- (2020) Roberto Littera et al. Frontiers in Immunology
- What defines an efficacious COVID-19 vaccine? A review of the challenges assessing the clinical efficacy of vaccines against SARS-CoV-2
- (2020) Susanne H Hodgson et al. LANCET INFECTIOUS DISEASES
- Role of Genetic Variants and Gene Expression in the Susceptibility and Severity of COVID-19
- (2020) Sarita Choudhary et al. Annals of Laboratory Medicine
- Association between the UGT1A1*28 allele and hyperbilirubinemia in HIV-positive patients receiving atazanavir: a meta-analysis
- (2019) Pengqiang Du et al. BIOSCIENCE REPORTS
- Clinical Pharmacogenetics Implementation Consortium ( CPIC ) Guideline for CYP 2B6 and Efavirenz‐containing Antiretroviral Therapy
- (2019) Zeruesenay Desta et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Select sequencing of clonally expanded CD8+ T cells reveals limits to clonal expansion
- (2019) Huang Huang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Anti-infective Properties of the Golden Spice Curcumin
- (2019) Dimas Praditya et al. Frontiers in Microbiology
- CYP2C9, VKORC1, and CYP4F2 polymorphisms and pediatric warfarin maintenance dose: a systematic review and meta-analysis
- (2019) Masanobu Takeuchi et al. PHARMACOGENOMICS JOURNAL
- Orally Efficacious Broad-Spectrum Ribonucleoside Analog Inhibitor of Influenza and Respiratory Syncytial Viruses
- (2018) Jeong-Joong Yoon et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Hydroxychloroquine: An old drug with new relevance
- (2018) E. A. SHIPPEY et al. CLEVELAND CLINIC JOURNAL OF MEDICINE
- Common variation near IRF6 is associated with IFN-β-induced liver injury in multiple sclerosis
- (2018) Kaarina Kowalec et al. NATURE GENETICS
- Influence of andrographolide on the pharmacokinetics of warfarin in rats
- (2018) Xiaoli Zhang et al. PHARMACEUTICAL BIOLOGY
- Association between HLA-B Alleles and Carbamazepine-Induced Maculopapular Exanthema and Severe Cutaneous Reactions in Thai Patients
- (2018) Chonlaphat Sukasem et al. Journal of Immunology Research
- Cryo-EM structure of the SARS coronavirus spike glycoprotein in complex with its host cell receptor ACE2
- (2018) Wenfei Song et al. PLoS Pathogens
- Effect of ABCB1 Genotypes on the Pharmacokinetics and Clinical Outcomes of New Oral Anticoagulants: A Systematic Review and Meta-analysis
- (2018) Qiufen Xie et al. CURRENT PHARMACEUTICAL DESIGN
- FCGR2A/FCGR3A Gene Polymorphisms and Clinical Variables as Predictors of Response to Tocilizumab and Rituximab in Patients With Rheumatoid Arthritis
- (2018) Alberto Jiménez Morales et al. JOURNAL OF CLINICAL PHARMACOLOGY
- Dapsone-induced severe cutaneous adverse drug reactions are strongly linked with HLA-B*13
- (2017) Therdpong Tempark et al. Pharmacogenetics and Genomics
- Genetic variation in the glucocorticoid pathway involved in interindividual differences in the glucocorticoid treatment
- (2017) Qian-Qian Song et al. PHARMACOGENOMICS
- Curcumin use in pulmonary diseases: State of the art and future perspectives
- (2017) Diana Lelli et al. PHARMACOLOGICAL RESEARCH
- Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses
- (2017) Timothy P. Sheahan et al. Science Translational Medicine
- Personalized vaccinology: A review
- (2017) G.A. Poland et al. VACCINE
- Association of HLA-A and HLA-B Alleles with Lamotrigine-Induced Cutaneous Adverse Drug Reactions in the Thai Population
- (2017) Napatrupron Koomdee et al. Frontiers in Pharmacology
- HLA Class I or Class II and Disease Association: Catch the Difference If You Can
- (2017) Maria Teresa Fiorillo et al. Frontiers in Immunology
- HLA-B*15:21 and carbamazepine-induced Stevens-Johnson syndrome: pooled-data and in silico analysis
- (2017) Kanoot Jaruthamsophon et al. Scientific Reports
- Antiviral CD8 + T Cells Restricted by Human Leukocyte Antigen Class II Exist during Natural HIV Infection and Exhibit Clonal Expansion
- (2016) Srinika Ranasinghe et al. IMMUNITY
- Inhibition of CYP2B6 by Medicinal Plant Extracts: Implication for Use of Efavirenz and Nevirapine-Based Highly Active Anti-Retroviral Therapy (HAART) in Resource-Limited Settings
- (2016) Nicholas Thomford et al. MOLECULES
- SARS and MERS: recent insights into emerging coronaviruses
- (2016) Emmie de Wit et al. NATURE REVIEWS MICROBIOLOGY
- Pharmacogenetics of ribavirin-induced anemia in HCV patients
- (2016) Antonio D'Avolio et al. PHARMACOGENOMICS
- Influence of IL6R gene polymorphisms in the effectiveness to treatment with tocilizumab in rheumatoid arthritis
- (2016) M Maldonado-Montoro et al. PHARMACOGENOMICS JOURNAL
- Genetic and clinical biomarkers of tocilizumab response in patients with rheumatoid arthritis
- (2016) Mar Maldonado-Montoro et al. PHARMACOLOGICAL RESEARCH
- Effect of Ginkgo Biloba Extract on the Pharmacokinetics and Metabolism of Clopidogrel in Rats
- (2016) Ying Deng et al. PHYTOTHERAPY RESEARCH
- ABCB1 and ABCC2 and the risk of distant metastasis in Thai breast cancer patients treated with tamoxifen
- (2016) Chonlaphat Sukasem et al. OncoTargets and Therapy
- HLA-B*58:01 for Allopurinol-Induced Cutaneous Adverse Drug Reactions: Implication for Clinical Interpretation in Thailand
- (2016) Chonlaphat Sukasem et al. Frontiers in Pharmacology
- Drug-Induced Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis Call for Optimum Patient Stratification and Theranostics via Pharmacogenomics
- (2015) Chonlaphat Sukasem et al. Annual Review of Genomics and Human Genetics
- Role of pharmacogenetic in ribavirin outcome prediction and pharmacokinetics in an Italian cohort of HCV-1 and 4 patients
- (2015) Sarah Allegra et al. BIOMEDICINE & PHARMACOTHERAPY
- Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline forUGT1A1and Atazanavir Prescribing
- (2015) RS Gammal et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Significant Association ofHLA-BAlleles and Genotypes in Thai Children with Autism Spectrum Disorders: A Case-Control Study
- (2015) Apichaya Puangpetch et al. DISEASE MARKERS
- Polymorphisms of the ApoE (Apolipoprotein E) Gene and Their Influence on Dyslipidemia in HIV-1-Infected Individuals
- (2015) Tanida Suwalak et al. JAPANESE JOURNAL OF INFECTIOUS DISEASES
- Successful pharmacogenetics-based optimization of unboosted atazanavir plasma exposure in HIV-positive patients: a randomized, controlled, pilot study (the REYAGEN study)
- (2015) S. Bonora et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- Herb–drug interaction between an anti-HIV Chinese herbal SH formula and atazanavir in vitro and in vivo
- (2015) Bao-Hui Cheng et al. JOURNAL OF ETHNOPHARMACOLOGY
- Oral ribavirin for respiratory syncytial virus infection after lung transplantation: Efficacy and cost-efficiency
- (2015) Fay S. Burrows et al. JOURNAL OF HEART AND LUNG TRANSPLANTATION
- Relationship between ITPA polymorphisms and hemolytic anemia in HCV-infected patients after ribavirin-based therapy: a meta-analysis
- (2015) Daniel Pineda-Tenor et al. Journal of Translational Medicine
- Polymorphisms associated with renal adverse effects of antiretroviral therapy in a Southern Brazilian HIV cohort
- (2015) Ivete M. da Rocha et al. Pharmacogenetics and Genomics
- PharmGKB summary
- (2015) Ellen M. McDonagh et al. Pharmacogenetics and Genomics
- Curcumin and its analogues: a potential natural compound against HIV infection and AIDS
- (2015) Sahdeo Prasad et al. Food & Function
- The role of C5a in acute lung injury induced by highly pathogenic viral infections
- (2015) Renxi Wang et al. Emerging Microbes & Infections
- Therapy and pharmacological properties of hydroxychloroquine and chloroquine in treatment of systemic lupus erythematosus, rheumatoid arthritis and related diseases
- (2015) K. D. Rainsford et al. INFLAMMOPHARMACOLOGY
- HLA-B allele and haplotype diversity among Thai patients identified by PCR-SSOP: evidence for high risk of drug-induced hypersensitivity
- (2015) Apichaya Puangpetch et al. Frontiers in Genetics
- UGT1A1 *6 polymorphism predicts outcome in elderly patients with relapsed or refractory diffuse large B-cell lymphoma treated with carboplatin, dexamethasone, etoposide and irinotecan
- (2014) Satoshi Yamasaki et al. ANNALS OF HEMATOLOGY
- CYP2B618492T→C Polymorphism Compromises Efavirenz Concentration in Coinfected HIV and Tuberculosis Patients CarryingCYP2B6Haplotype *1/*1
- (2014) Weerawat Manosuthi et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Pharmacogenetics and Clinical Biomarkers for Subtherapeutic Plasma Efavirenz Concentration in HIV-1 Infected Thai Adults
- (2014) Chonlaphat Sukasem et al. Drug Metabolism and Pharmacokinetics
- Development of Pyrosequencing Method for Detection ofUGT1A1Polymorphisms in Thai Colorectal Cancers
- (2014) Chonlaphat Sukasem et al. JOURNAL OF CLINICAL LABORATORY ANALYSIS
- d-Dimer elevation and adverse outcomes
- (2014) Rim Halaby et al. JOURNAL OF THROMBOSIS AND THROMBOLYSIS
- Toxicogenetics of lopinavir/ritonavir in HIV-infected European patients
- (2014) Elena López Aspiroz et al. Personalized Medicine
- Influence of ABCB1 gene polymorphisms on the pharmacokinetics of azithromycin among healthy Chinese Han ethnic subjects
- (2014) Xiao-Jing He et al. Pharmacological Reports
- Pharmacokinetics, Metabolism, and Excretion of the Antiviral Drug Arbidol in Humans
- (2013) Pan Deng et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Simultaneous Pharmacogenetics-Based Population Pharmacokinetic Analysis of Darunavir and Ritonavir in HIV-Infected Patients
- (2013) José Moltó et al. CLINICAL PHARMACOKINETICS
- Clinical Pharmacogenetics Implementation Consortium Guidelines for CYP2C19 Genotype and Clopidogrel Therapy: 2013 Update
- (2013) S A Scott et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Andrographis paniculataExtract and Andrographolide Modulate the Hepatic Drug Metabolism System and Plasma Tolbutamide Concentrations in Rats
- (2013) Haw-Wen Chen et al. Evidence-based Complementary and Alternative Medicine
- Novel Inhibitors of Severe Acute Respiratory Syndrome Coronavirus Entry That Act by Three Distinct Mechanisms
- (2013) A. O. Adedeji et al. JOURNAL OF VIROLOGY
- Pharmacogenetic markers of CYP2B6 associated with efavirenz plasma concentrations in HIV-1 infected Thai adults
- (2012) Chonlaphat Sukasem et al. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
- Carboxylesterase 1 Polymorphism Impairs Oseltamivir Bioactivation in Humans
- (2012) E K Tarkiainen et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Herb-Drug Interactions and Mechanistic and Clinical Considerations
- (2012) Xiao-Wu Chen et al. CURRENT DRUG METABOLISM
- An update on the ability of St. John's wort to affect the metabolism of other drugs
- (2012) Roja Rahimi et al. Expert Opinion on Drug Metabolism & Toxicology
- Genome-wide association study of plasma efavirenz pharmacokinetics in AIDS Clinical Trials Group protocols implicates several CYP2B6 variants
- (2012) Emily R. Holzinger et al. Pharmacogenetics and Genomics
- Influence of CYP2C9 and VKORC1 on Patient Response to Warfarin: A Systematic Review and Meta-Analysis
- (2012) Andrea L. Jorgensen et al. PLoS One
- CYP2C9-Mediated Metabolic Activation of Losartan Detected by a Highly Sensitive Cell-Based Screening Assay
- (2011) A. Iwamura et al. DRUG METABOLISM AND DISPOSITION
- Genome-wide association study identified ITPA/DDRGK1 variants reflecting thrombocytopenia in pegylated interferon and ribavirin therapy for chronic hepatitis C
- (2011) Yasuhito Tanaka et al. HUMAN MOLECULAR GENETICS
- In vitro determination of the effect of Andrographis paniculata extracts and andrographolide on human hepatic cytochrome P450 activities
- (2011) Yan Pan et al. Journal of Natural Medicines
- CYP3A5, ABCB1, and SLCO1B1 Polymorphisms and Pharmacokinetics and Virologic Outcome of Lopinavir/Ritonavir in HIV-Infected Children
- (2011) Natella Y Rakhmanina et al. THERAPEUTIC DRUG MONITORING
- Herb-Drug Interaction betweenEchinacea purpureaand Darunavir-Ritonavir in HIV-Infected Patients
- (2010) José Moltó et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- ADME pharmacogenetics: investigation of the pharmacokinetics of the antiretroviral agent lopinavir coformulated with ritonavir
- (2010) Rubin Lubomirov et al. Pharmacogenetics and Genomics
- Echinacea purpureaSignificantly Induces Cytochrome P450 3A Activity but Does Not Alter Lopinavir-Ritonavir Exposure in Healthy Subjects
- (2010) Scott R Penzak et al. PHARMACOTHERAPY
- HLA-DRB1*01 associated with cutaneous hypersensitivity induced by nevirapine and efavirenz
- (2009) Zulma G Vitezica et al. AIDS
- A novel polymorphism in ABCB1 gene, CYP2B6*6 and sex predict single-dose efavirenz population pharmacokinetics in Ugandans
- (2009) Jackson K. Mukonzo et al. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
- Effect of silymarin on the pharmacokinetics of losartan and its active metabolite E-3174 in healthy Chinese volunteers
- (2009) Yang Han et al. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
- The spike protein of SARS-CoV — a target for vaccine and therapeutic development
- (2009) Lanying Du et al. NATURE REVIEWS MICROBIOLOGY
- The Pharmacokinetics and Interactions of Ivermectin in Humans—A Mini-review
- (2008) Aránzazu González Canga et al. AAPS Journal
- Genetic polymorphisms differently influencing the emergence of atrophy and fat accumulation in HIV-related lipodystrophy
- (2008) Barbara Zanone Poma et al. AIDS
- Effects of Andrographis paniculata extract and Andrographolide on hepatic cytochrome P450 mRNA expression and monooxygenase activities after in vivo administration to rats and in vitro in rat and human hepatocyte cultures
- (2008) Dumrongsak Pekthong et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Effect of Ginkgo biloba extract on lopinavir, midazolam and fexofenadine pharmacokinetics in healthy subjects
- (2008) Sarah M. Robertson et al. CURRENT MEDICAL RESEARCH AND OPINION
- Differential inhibition of rat and human hepatic cytochrome P450 by Andrographis paniculata extract and andrographolide
- (2007) D. Pekthong et al. JOURNAL OF ETHNOPHARMACOLOGY
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