Inhibition of drug-metabolizing enzymes by Qingfei Paidu decoction: Implication of herb-drug interactions in COVID-19 pharmacotherapy

Theophylline acetaldehyde as the initial product in Doxophylline metabolism in human liver

(2020) Xiaohua Zhao et al.   DRUG METABOLISM AND DISPOSITION

Metabolism of JQ1, an inhibitor of bromodomain and extra terminal bromodomain proteins, in human and mouse liver microsomes†

(2020) Feng Li et al.   BIOLOGY OF REPRODUCTION

Protection against COVID-19 injury by Qingfei Paidu decoction via anti-viral, anti-inflammatory activity and metabolic programming

(2020) Jian Chen et al.   BIOMEDICINE & PHARMACOTHERAPY

Quadruple therapy for asymptomatic COVID-19 infection patients

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Pharmacokinetic interaction between a Chinese herbal formula Huosu Yangwei oral liquid and apatinib in vitro and in vivo

(2020) Sheng-Quan Fang et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Treatment efficacy analysis of traditional Chinese medicine for novel coronavirus pneumonia (COVID-19): an empirical study from Wuhan, Hubei Province, China

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Clinical characteristics of older patients infected with COVID-19: A descriptive study

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Chemical composition and pharmacological mechanism of Qingfei Paidu Decoction and Ma Xing Shi Gan Decoction against Coronavirus Disease 2019 (COVID-19): In silico and experimental study

(2020) Ruocong Yang et al.   PHARMACOLOGICAL RESEARCH

Combating COVID-19 with integrated traditional Chinese and Western medicine in China

(2020) Liqiang Ni et al.   Acta Pharmaceutica Sinica B

Clinical retrospective study on the efficacy of Qingfei Paidu decoction combined with Western medicine for COVID-19 treatment

(2020) Siyi Xin et al.   BIOMEDICINE & PHARMACOTHERAPY

Phosmet bioactivation by isoform-specific cytochrome P450s in human hepatic and gut samples and metabolic interaction with chlorpyrifos

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Systems pharmacological study illustrates the immune regulation, anti-infection, anti-inflammation, and multi-organ protection mechanism of Qing-Fei-Pai-Du decoction in the treatment of COVID-19

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Herb-drug interaction between Styrax and warfarin: Molecular basis and mechanism

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Molecular probes for human cytochrome P450 enzymes: Recent progress and future perspectives

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Inhibition of human carboxylesterases by magnolol: Kinetic analyses and mechanism

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Discovery of a highly specific and efficacious inhibitor of human carboxylesterase 2 by large-scale screening

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Nevadensin is a naturally occurring selective inhibitor of human carboxylesterase 1

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Comparative pharmacokinetic evaluation of lopinavir and lopinavir-loaded solid lipid nanoparticles in hepatic impaired rat model

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A bioluminescent sensor for highly selective and sensitive detection of human carboxylesterase 1 in complex biological samples

(2016) Dan-Dan Wang et al.   CHEMICAL COMMUNICATIONS

Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys

(2016) Travis K. Warren et al.   NATURE

A Two-Photon Ratiometric Fluorescent Probe for Imaging Carboxylesterase 2 in Living Cells and Tissues

(2015) Qiang Jin et al.   ACS Applied Materials & Interfaces

Psoralen, a mechanism-based inactivator of CYP2B6

(2015) Lin Ji et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Pharmacokinetic interactions between 20(S)-ginsenoside Rh2 and the HIV protease inhibitor ritonavir in vitro and in vivo

(2013) Jian Shi et al.   ACTA PHARMACOLOGICA SINICA

Evidence for Time-Dependent Interactions between Ritonavir and Lopinavir/Ritonavir Plasma Levels Following P-Glycoprotein Inhibition in Sprague-Dawley Rats

(2011) Michael du Plooy et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Prediction of time-dependent CYP3A4 drug–drug interactions by physiologically based pharmacokinetic modelling: Impact of inactivation parameters and enzyme turnover

(2011) K. Rowland Yeo et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Arachidonic Acid-metabolizing Cytochrome P450 Enzymes Are Targets of ω-3 Fatty Acids

(2010) Cosima Arnold et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Time-dependent inhibition (TDI) of CYP3A4 and CYP2C9 by noscapine potentially explains clinical noscapine-warfarin interaction

(2009) Zhong-Ze Fang et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY