Targeting potential drivers of COVID-19: Neutrophil extracellular traps

Clinical predictors of mortality due to COVID-19 based on an analysis of data of 150 patients from Wuhan, China

(2020) Qiurong Ruan et al.   INTENSIVE CARE MEDICINE

Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus–Infected Pneumonia in Wuhan, China

(2020) Dawei Wang et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study

(2020) Nanshan Chen et al.   LANCET

Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China

(2020) Chaolin Huang et al.   LANCET

Programmed ‘disarming’ of the neutrophil proteome reduces the magnitude of inflammation

(2020) Jose M. Adrover et al.   NATURE IMMUNOLOGY

Functional exhaustion of antiviral lymphocytes in COVID-19 patients

(2020) Meijuan Zheng et al.   Cellular & Molecular Immunology

The use of anti-inflammatory drugs in the treatment of people with severe coronavirus disease 2019 (COVID-19): The Perspectives of clinical immunologists from China

(2020) Wen Zhang et al.   CLINICAL IMMUNOLOGY

TH17 responses in cytokine storm of COVID-19: An emerging target of JAK2 inhibitor Fedratinib

(2020) Dandan Wu et al.   JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION

Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study

(2020) Fei Zhou et al.   LANCET

COVID-19: consider cytokine storm syndromes and immunosuppression

(2020) Puja Mehta et al.   LANCET

Risk Factors Associated With Acute Respiratory Distress Syndrome and Death in Patients With Coronavirus Disease 2019 Pneumonia in Wuhan, China

(2020) Chaomin Wu et al.   JAMA Internal Medicine

Association of Coronavirus Disease 2019 (COVID-19) With Myocardial Injury and Mortality

(2020) Robert O. Bonow et al.   JAMA Cardiology

Neutrophil Extracellular Traps in Arterial and Venous Thrombosis

(2019) Elodie Laridan et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Extracellular DNA, Neutrophil Extracellular Traps, and Inflammasome Activation in Severe Asthma

(2019) Marrah E Lachowicz-Scroggins et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Neutrophil Extracellular Traps Are Elevated in Patients with Pneumonia-related Acute Respiratory Distress Syndrome

(2019) Inès Bendib et al.   ANESTHESIOLOGY

Novel Role of IL (Interleukin)-1β in Neutrophil Extracellular Trap Formation and Abdominal Aortic AneurysmsHighlights

(2018) Akshaya K. Meher et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Markers of neutrophil extracellular traps predict adverse outcome in community-acquired pneumonia: secondary analysis of a randomised controlled trial

(2018) Fahim Ebrahimi et al.   EUROPEAN RESPIRATORY JOURNAL

Neutrophil peptidyl arginine deiminase-4 has a pivotal role in ischemia/reperfusion-induced acute kidney injury

(2018) Wesley M. Raup-Konsavage et al.   KIDNEY INTERNATIONAL

Neutrophil extracellular traps promote lipopolysaccharide-induced airway inflammation and mucus hypersecretion in mice

(2018) Yong Zou et al.   Oncotarget

Histones and Neutrophil Extracellular Traps Enhance Tubular Necrosis and Remote Organ Injury in Ischemic AKI

(2017) Daigo Nakazawa et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Release of extracellular DNA influences renal ischemia reperfusion injury by platelet activation and formation of neutrophil extracellular traps

(2017) Marcel P.B. Jansen et al.   KIDNEY INTERNATIONAL

An emerging role for neutrophil extracellular traps in noninfectious disease

(2017) Selina K Jorch et al.   NATURE MEDICINE

How Should Aerosols Be Delivered During Invasive Mechanical Ventilation?

(2017) Rajiv Dhand   Respiratory Care

Host DNases prevent vascular occlusion by neutrophil extracellular traps

(2017) Miguel Jiménez-Alcázar et al.   SCIENCE

Cytokine storm and sepsis disease pathogenesis

(2017) Benjamin G. Chousterman et al.   Seminars in Immunopathology

Pathogenic human coronavirus infections: causes and consequences of cytokine storm and immunopathology

(2017) Rudragouda Channappanavar et al.   Seminars in Immunopathology

Understanding the Entanglement: Neutrophil Extracellular Traps (NETs) in Cystic Fibrosis

(2017) Saira R. Martínez-Alemán et al.   Frontiers in Cellular and Infection Microbiology

Macrophage-derived IL-1β enhances monosodium urate crystal-triggered NET formation

(2016) Payel Sil et al.   INFLAMMATION RESEARCH

Neonatal NET-inhibitory factor and related peptides inhibit neutrophil extracellular trap formation

(2016) Christian C. Yost et al.   JOURNAL OF CLINICAL INVESTIGATION

Cancer cells induce metastasis-supporting neutrophil extracellular DNA traps

(2016) J. Park et al.   Science Translational Medicine

Neutrophil Extracellular Traps Go Viral

(2016) Günther Schönrich et al.   Frontiers in Immunology

Neutrophil extracellular traps are indirectly triggered by lipopolysaccharide and contribute to acute lung injury

(2016) Shuai Liu et al.   Scientific Reports

Neutrophil Extracellular Traps Accumulate in Peripheral Blood Vessels and Compromise Organ Function in Tumor-Bearing Animals

(2015) J. Cedervall et al.   CANCER RESEARCH

Sepsis and ARDS: The Dark Side of Histones

(2015) Zhiheng Xu et al.   MEDIATORS OF INFLAMMATION

Neutrophil extracellular traps license macrophages for cytokine production in atherosclerosis

(2015) A. Warnatsch et al.   SCIENCE

IL-6 biology: implications for clinical targeting in rheumatic disease

(2014) Leonard H. Calabrese et al.   Nature Reviews Rheumatology

Neutrophils scan for activated platelets to initiate inflammation

(2014) Vinatha Sreeramkumar et al.   SCIENCE

Elevated Levels of Circulating DNA and Chromatin Are Independently Associated With Severe Coronary Atherosclerosis and a Prothrombotic State

(2013) Julian I. Borissoff et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Thrombosis: tangled up in NETs

(2013) K. Martinod et al.   BLOOD

Functional IL6R 358Ala Allele Impairs Classical IL-6 Receptor Signaling and Influences Risk of Diverse Inflammatory Diseases

(2013) Ricardo C. Ferreira et al.   PLoS Genetics

Neutrophil Extracellular Trap (NET) Impact on Deep Vein Thrombosis

(2012) Tobias A. Fuchs et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Extracellular DNA traps are associated with the pathogenesis of TRALI in humans and mice

(2012) G. M. Thomas et al.   BLOOD

The IL6R variation Asp358Ala is a potential modifier of lung function in subjects with asthma

(2012) Gregory A. Hawkins et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Platelets induce neutrophil extracellular traps in transfusion-related acute lung injury

(2012) Axelle Caudrillier et al.   JOURNAL OF CLINICAL INVESTIGATION

Monocytes, neutrophils, and platelets cooperate to initiate and propagate venous thrombosis in mice in vivo

(2012) Marie-Luise von Brühl et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Neutrophil Extracellular Traps: Double-Edged Swords of Innate Immunity

(2012) M. J. Kaplan et al.   JOURNAL OF IMMUNOLOGY

Neutrophil Extracellular Trap-Associated Protein Activation of the NLRP3 Inflammasome Is Enhanced in Lupus Macrophages

(2012) J. M. Kahlenberg et al.   JOURNAL OF IMMUNOLOGY

Activation of PAD4 in NET formation

(2012) Amanda S. Rohrbach et al.   Frontiers in Immunology

Excessive Neutrophils and Neutrophil Extracellular Traps Contribute to Acute Lung Injury of Influenza Pneumonitis

(2011) Teluguakula Narasaraju et al.   AMERICAN JOURNAL OF PATHOLOGY

Extracellular histones promote thrombin generation through platelet-dependent mechanisms: involvement of platelet TLR2 and TLR4

(2011) F. Semeraro et al.   BLOOD

Ultrastructural characterization of cystic fibrosis sputum using atomic force and scanning electron microscopy

(2011) Reinhard Manzenreiter et al.   Journal of Cystic Fibrosis

Neutrophil Elastase Enhances Sputum Solubilization in Cystic Fibrosis Patients Receiving DNase Therapy

(2011) Venizelos Papayannopoulos et al.   PLoS One

Neutrophil elastase and myeloperoxidase regulate the formation of neutrophil extracellular traps

(2010) Venizelos Papayannopoulos et al.   JOURNAL OF CELL BIOLOGY

Reciprocal coupling of coagulation and innate immunity via neutrophil serine proteases

(2010) Steffen Massberg et al.   NATURE MEDICINE

Extracellular DNA traps promote thrombosis

(2010) T. A. Fuchs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activation of the Human Contact System on Neutrophil Extracellular Traps

(2009) Sonja Oehmcke et al.   Journal of Innate Immunity

Targeting the Pathogenic Role of Interleukin 1β in the Progression of Smoldering/Indolent Myeloma to Active Disease

(2009) Charles A. Dinarello   MAYO CLINIC PROCEEDINGS

Extracellular histones are major mediators of death in sepsis

(2009) Jun Xu et al.   NATURE MEDICINE

Sepsis: the dark side of histones

(2009) Catherine Chaput et al.   NATURE MEDICINE

Netting neutrophils in autoimmune small-vessel vasculitis

(2009) Kai Kessenbrock et al.   NATURE MEDICINE

Extracellular DNA Is Required for Root Tip Resistance to Fungal Infection

(2009) F. Wen et al.   PLANT PHYSIOLOGY