Activity-based fluorescence probes for pathophysiological peroxynitrite fluxes

Indication of Dynamic Peroxynitrite Fluctuations in the Rat Epilepsy Model with a Near-Infrared Two-Photon Fluorescent Probe

(2021) Xianzhu Luo et al.   ANALYTICAL CHEMISTRY

Highly Sensitive Near-Infrared Imaging of Peroxynitrite Fluxes in Inflammation Progress

(2021) Zhao Wang et al.   ANALYTICAL CHEMISTRY

The redox language in neurodegenerative diseases: oxidative post-translational modifications by hydrogen peroxide

(2021) Yew Mun Lee et al.   Cell Death & Disease

Recent Progress in Fluorescent Sensors for Drug-Induced Liver Injury Assessment

(2021) Jiao Chen et al.   ACS Sensors

Nonoxidative Strategy for Monitoring Peroxynitrite Fluctuations in Immune Responses of Tumorigenesis

(2021) Jiao Lu et al.   ANALYTICAL CHEMISTRY

High‐Contrast Fluorescence Diagnosis of Cancer Cells/Tissues Based on β‐Lapachone‐Triggered ROS Amplification Specific in Cancer Cells

(2021) Jing Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Mitochondria-Targeting and Reversible Near-Infrared Emissive Iridium(III) Probe for in vivo ONOO–/GSH Redox Cycles Monitoring

(2021) Weijun Wu et al.   ANALYTICAL CHEMISTRY

Two-Photon, Ratiometric, Quantitative Fluorescent Probe Reveals Fluctuation of Peroxynitrite Regulated by Arginase 1

(2021) Shiyu Chen et al.   ANALYTICAL CHEMISTRY

Cyanine‐Dyad Molecular Probe for the Simultaneous Profiling of the Evolution of Multiple Radical Species During Bacterial Infections

(2021) Zhimin Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent developments of BODIPY-based colorimetric and fluorescent probes for the detection of reactive oxygen/nitrogen species and cancer diagnosis

(2021) Van-Nghia Nguyen et al.   COORDINATION CHEMISTRY REVIEWS

Dual-locked spectroscopic probes for sensing and therapy

(2021) Luling Wu et al.   Nature Reviews Chemistry

Recent advances in reaction-based fluorescent probes for the detection of central nervous system-related pathologies in vivo

(2021) Ya-Lin Qi et al.   COORDINATION CHEMISTRY REVIEWS

Reasonably constructed NIR fluorescent probes based on dicyanoisophorone skeleton for imaging ONOO− in living cells

(2021) Jeewon Chung et al.   DYES AND PIGMENTS

Ultrafast Detection of Peroxynitrite in Parkinson’s Disease Models Using a Near-Infrared Fluorescent Probe

(2020) Qian Sun et al.   ANALYTICAL CHEMISTRY

Aggregation-Induced Emission: New Vistas at Aggregate Level

(2020) Ben Zhong Tang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Aggregation-Induced Emission: Recent Advances in Materials and Biomedical Applications

(2020) Xiaolei Cai et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

ROS in cancer therapy: the bright side of the moon

(2020) Bruno Perillo et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

The entry of nanoparticles into solid tumours

(2020) Shrey Sindhwani et al.   NATURE MATERIALS

Fluorescent Imaging of Reactive Oxygen and Nitrogen Species Associated with Pathophysiological Processes

(2020) Ji-Ting Hou et al.   Chem

Advances in activity-based sensing probes for isoform-selective imaging of enzymatic activity

(2020) Sarah H. Gardner et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Reactive oxygen species (ROS) as pleiotropic physiological signalling agents

(2020) Helmut Sies et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

High-Selectivity Fluorescent Reporter toward Peroxynitrite in a Coexisting Nonalcoholic Fatty Liver and Drug-Induced Liver Diseases Model

(2020) Dan Cheng et al.   ANALYTICAL CHEMISTRY

NIR‐II AIEgens: A Win‐Win Integration towards Bioapplications

(2020) Wenhan Xu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Molecular Engineering of NIR‐II Fluorophores for Improved Biomedical Detection

(2020) Fan Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Advanced Fluorescence Imaging Technology in the Near-Infrared-II Window for Biomedical Applications

(2020) Chunyan Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cell death in chronic inflammation: breaking the cycle to treat rheumatic disease

(2020) Holly Anderton et al.   Nature Reviews Rheumatology

The Complex Interplay between Antioxidants and ROS in Cancer

(2020) Isaac S. Harris et al.   TRENDS IN CELL BIOLOGY

Red Blood Cell Peroxynitrite Causes Endothelial Dysfunction in Type 2 Diabetes Mellitus via Arginase

(2020) Ali Mahdi et al.   Cells

Activatable Two-Photon Near-Infrared Fluorescent Probe Tailored toward Peroxynitrite In Vivo Imaging in Tumors

(2020) Weiwei Wang et al.   ANALYTICAL CHEMISTRY

Visualization of ONOO– and Viscosity in Drug-Induced Hepatotoxicity with Different Fluorescence Signals by a Sensitive Fluorescent Probe

(2020) Yingzhen Deng et al.   ANALYTICAL CHEMISTRY

Activity‐Based NIR Enzyme Fluorescent Probes for the Diagnosis of Tumors and Image‐Guided Surgery

(2020) Juyoung Yoon et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A General Strategy for Development of Activatable NIR‐II Fluorescent Probes for in vivo High‐Contrast Bioimaging

(2020) Xiao-Bing Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Kinase inhibition in autoimmunity and inflammation

(2020) Ali A. Zarrin et al.   NATURE REVIEWS DRUG DISCOVERY

A two-photon fluorescent probe for visualizing endoplasmic reticulum peroxynitrite in Parkinson's disease models

(2020) Ming Yan et al.   SENSORS AND ACTUATORS B-CHEMICAL

Visualizing Peroxynitrite in Microvessels of the Brain with Stroke Using an Engineered Highly Specific Fluorescent Probe

(2020) Jianhua Xiong et al.   ACS Sensors

Design Strategy of Fluorescent Probes for Live Drug-Induced Acute Liver Injury Imaging

(2020) Dan Cheng et al.   ACCOUNTS OF CHEMICAL RESEARCH

Fluorescent probes for pH and alkali metal ions

(2020) Weijie Chen et al.   COORDINATION CHEMISTRY REVIEWS

Reactive oxygen species, thiols and enzymes activable AIEgens from single fluorescence imaging to multifunctional theranostics

(2020) Jun Li et al.   COORDINATION CHEMISTRY REVIEWS

Metal-coordinated fluorescent and luminescent probes for reactive oxygen species (ROS) and reactive nitrogen species (RNS)

(2020) Nahyun Kwon et al.   COORDINATION CHEMISTRY REVIEWS

Inflammation, Infectious Triggers, and Parkinson's Disease

(2019) Elisa Caggiu et al.   Frontiers in Neurology

De novo design of chemical stability near-infrared molecular probes for high-fidelity hepatotoxicity evaluation in vivo

(2019) Dan Cheng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Peroxynitrite Activatable NIR-II Fluorescent Molecular Probe for Drug-Induced Hepatotoxicity Monitoring

(2019) Dandan Li et al.   ANALYTICAL CHEMISTRY

A Facile, Versatile, and Highly Efficient Strategy for Peroxynitrite Bioimaging Enabled by Formamide Deformylation

(2019) Xilei Xie et al.   ANALYTICAL CHEMISTRY

Stable, Wavelength-Tunable Fluorescent Dyes in the NIR-II Region for In Vivo High-Contrast Bioimaging and Multiplexed Biosensing

(2019) Zuhai Lei et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Reactive Oxygen Species (ROS)-Based Nanomedicine

(2019) Bowen Yang et al.   CHEMICAL REVIEWS

Visualization of Lung Inflammation to Pulmonary Fibrosis via Peroxynitrite Fluctuation

(2019) Zixuan Zhan et al.   ANALYTICAL CHEMISTRY

Coumarin-Based Small-Molecule Fluorescent Chemosensors

(2019) Duxia Cao et al.   CHEMICAL REVIEWS

Inflammation and Cancer: Triggers, Mechanisms, and Consequences

(2019) Florian R. Greten et al.   IMMUNITY

Inorganic Chemistry Approaches to Activity-Based Sensing: From Metal Sensors to Bioorthogonal Metal Chemistry

(2019) Diana A. Iovan et al.   INORGANIC CHEMISTRY

Imaging Dynamic Peroxynitrite Fluxes in Epileptic Brains with a Near‐Infrared Fluorescent Probe

(2019) Jiong‐sheng Hu et al.   Advanced Science

Activity-Based Sensing and Theranostic Probes Based on Photoinduced Electron Transfer

(2019) Wen Sun et al.   ACCOUNTS OF CHEMICAL RESEARCH

Aggregation-Induced Emission Luminogens for Activity-Based Sensing

(2019) Dong Wang et al.   ACCOUNTS OF CHEMICAL RESEARCH

A near-infrared fluorescence probe for ultrafast and selective detection of peroxynitrite with large Stokes shift in inflamed mouse models

(2019) Mengyao Zhu et al.   DYES AND PIGMENTS

Reaction-Based Luminescent Probes for Reactive Sulfur, Oxygen, and Nitrogen Species: Analytical Techniques and Recent Progress

(2019) Briley J. Bezner et al.   ANALYTICAL CHEMISTRY

Activity-Based Sensing: A Synthetic Methods Approach for Selective Molecular Imaging and Beyond

(2019) Kevin J Bruemmer et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ischaemic stroke

(2019) Bruce C. V. Campbell et al.   Nature Reviews Disease Primers

In situ and real-time imaging of superoxide anion and peroxynitrite elucidating arginase 1 nitration aggravating hepatic ischemia-reperfusion injury

(2019) Wen Zhang et al.   BIOMATERIALS

Near-infrared fluorescent probe with rapid response and large Stokes shift for imaging peroxynitrite in living cells, zebrafish and mice

(2019) Xinyu Yin et al.   DYES AND PIGMENTS

Chronic inflammation in the etiology of disease across the life span

(2019) David Furman et al.   NATURE MEDICINE

A Dual-Modal Molecular Probe for Near-Infrared Fluorescence and Photoacoustic Imaging of Peroxynitrite

(2018) Jianjian Zhang et al.   ANALYTICAL CHEMISTRY

A Bioluminescent Probe for Imaging Endogenous Peroxynitrite in Living Cells and Mice

(2018) Jun-Bin Li et al.   ANALYTICAL CHEMISTRY

A Two-Photon Fluorescent Probe for Imaging Endogenous ONOO– near NMDA Receptors in Neuronal Cells and Hippocampal Tissues

(2018) Dayoung Lee et al.   ANALYTICAL CHEMISTRY

A Ratiometric Two-Photon Fluorescent Probe for Tracking Lysosomal ATP: Direct In Cellulo Observation of Lysosomal Membrane Fusion Processes

(2018) Yong Woong Jun et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Biochemistry of Peroxynitrite and Protein Tyrosine Nitration

(2018) Gerardo Ferrer-Sueta et al.   CHEMICAL REVIEWS

Crucial breakthrough of second near-infrared biological window fluorophores: design and synthesis toward multimodal imaging and theranostics

(2018) Shuqing He et al.   CHEMICAL SOCIETY REVIEWS

Fluorogenic reaction-based prodrug conjugates as targeted cancer theranostics

(2018) Min Hee Lee et al.   CHEMICAL SOCIETY REVIEWS

Fluorescent probes for the simultaneous detection of multiple analytes in biology

(2018) Jacek L. Kolanowski et al.   CHEMICAL SOCIETY REVIEWS

Design and applications of fluorescent detectors for peroxynitrite

(2018) Shan Wang et al.   COORDINATION CHEMISTRY REVIEWS

Fluorescence and chemiluminescence approaches for peroxynitrite detection

(2018) Carolina Prolo et al.   FREE RADICAL BIOLOGY AND MEDICINE

A chemiluminescent probe for cellular peroxynitrite using a self-immolative oxidative decarbonylation reaction

(2018) Jian Cao et al.   Chemical Science

A Si-rhodamine-based near-infrared fluorescent probe for visualizing endogenous peroxynitrite in living cells, tissues, and animals

(2018) Junfeng Miao et al.   Journal of Materials Chemistry B

Multimodal Biophotonics of Semiconducting Polymer Nanoparticles

(2018) Yuyan Jiang et al.   ACCOUNTS OF CHEMICAL RESEARCH

Targeting Fluorescent Sensors to Endoplasmic Reticulum Membranes Enables Detection of Peroxynitrite During Cellular Phagocytosis

(2018) Kelsey E. Knewtson et al.   ACS Chemical Biology

Mitochondrial Peroxynitrite Mediation of Anthracycline-Induced Cardiotoxicity as Visualized by a Two-Photon Near-Infrared Fluorescent Probe

(2018) Xilei Xie et al.   ANALYTICAL CHEMISTRY

A ratiometric fluorescent probe for peroxynitrite prepared by de novo synthesis and its application in assessing the mitochondrial oxidative stress status in cells and in vivo

(2018) Dong-Ye Zhou et al.   CHEMICAL COMMUNICATIONS

Lysosomal membrane permeabilization and cell death

(2018) Fengjuan Wang et al.   TRAFFIC

Alcoholic liver disease

(2018) Helmut K. Seitz et al.   Nature Reviews Disease Primers

An ESIPT Probe for the Ratiometric Imaging of Peroxynitrite Facilitated by Binding to Aβ-Aggregates

(2018) Adam C. Sedgwick et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Small-Molecule Fluorescent Probes for Live-Cell Super-Resolution Microscopy

(2018) Lu Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Photostable Ratiometric Pdot Probe for in Vitro and in Vivo Imaging of Hypochlorous Acid

(2017) Li Wu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Two-photon fluorescent probe for revealing drug-induced hepatotoxicity via mapping fluctuation of peroxynitrite

(2017) Yong Li et al.   Chemical Science

Novel bright-emission small-molecule NIR-II fluorophores for in vivo tumor imaging and image-guided surgery

(2017) Yao Sun et al.   Chemical Science

Aromatization of 9,10-Dihydroacridine Derivatives: Discovering a Highly Selective and Rapid-Responding Fluorescent Probe for Peroxynitrite

(2017) Zhi-heng Li et al.   ACS Sensors

Activatable Fluorescent Nanoprobe with Aggregation-Induced Emission Characteristics for Selective In Vivo Imaging of Elevated Peroxynitrite Generation

(2016) Zhegang Song et al.   ADVANCED MATERIALS

Rational Design of an α-Ketoamide-Based Near-Infrared Fluorescent Probe Specific for Hydrogen Peroxide in Living Systems

(2016) Xilei Xie et al.   ANALYTICAL CHEMISTRY

Boronate based fluorescence (ESIPT) probe for peroxynitrite

(2016) Adam C. Sedgwick et al.   CHEMICAL COMMUNICATIONS

Recent progress in the development of fluorescent, luminescent and colorimetric probes for detection of reactive oxygen and nitrogen species

(2016) Xiaoqiang Chen et al.   CHEMICAL SOCIETY REVIEWS

Selective Visualization of the Endogenous Peroxynitrite in an Inflamed Mouse Model by a Mitochondria-Targetable Two-Photon Ratiometric Fluorescent Probe

(2016) Dan Cheng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

FRET-Based Mito-Specific Fluorescent Probe for Ratiometric Detection and Imaging of Endogenous Peroxynitrite: Dyad of Cy3 and Cy5

(2016) Xiaotong Jia et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rational design of reversible fluorescent probes for live-cell imaging and quantification of fast glutathione dynamics

(2016) Keitaro Umezawa et al.   Nature Chemistry

Resolution of inflammation: a new therapeutic frontier

(2016) James N. Fullerton et al.   NATURE REVIEWS DRUG DISCOVERY

A rationally designed rhodamine-based fluorescent probe for molecular imaging of peroxynitrite in live cells and tissues

(2016) Tao Peng et al.   Chemical Science

ROS homeostasis and metabolism: a dangerous liason in cancer cells

(2016) E Panieri et al.   Cell Death & Disease

Small-Molecule Two-Photon Probes for Bioimaging Applications

(2015) Hwan Myung Kim et al.   CHEMICAL REVIEWS

Rapid mitochondrial dysfunction mediates TNF-alpha-induced neurotoxicity

(2015) Danielle N. Doll et al.   JOURNAL OF NEUROCHEMISTRY

Visualizing Peroxynitrite Fluxes in Endothelial Cells Reveals the Dynamic Progression of Brain Vascular Injury

(2015) Xin Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Inflammation and cancer: advances and new agents

(2015) Shanthini M. Crusz et al.   Nature Reviews Clinical Oncology

Alcoholic liver disease: mechanisms of injury and targeted treatment

(2015) Alexandre Louvet et al.   Nature Reviews Gastroenterology & Hepatology

Immune attack: the role of inflammation in Alzheimer disease

(2015) Frank L. Heppner et al.   NATURE REVIEWS NEUROSCIENCE

Nonalcoholic fatty liver disease

(2015) Elizabeth M. Brunt et al.   Nature Reviews Disease Primers

G1-4A, a polysaccharide from Tinospora cordifolia induces peroxynitrite dependent killer dendritic cell (KDC) activity against tumor cells

(2014) Vipul K. Pandey et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Selective and Ratiometric Fluorescent Trapping and Quantification of Protein Vicinal Dithiols and in Situ Dynamic Tracing in Living Cells

(2014) Chusen Huang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Molecular Imaging of Peroxynitrite with HKGreen-4 in Live Cells and Tissues

(2014) Tao Peng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Real-time imaging of oxidative and nitrosative stress in the liver of live animals for drug-toxicity testing

(2014) Adam J Shuhendler et al.   NATURE BIOTECHNOLOGY

Mitochondrial Reactive Oxygen Species (ROS) and ROS-Induced ROS Release

(2014) Dmitry B. Zorov et al.   PHYSIOLOGICAL REVIEWS

A Ratiometric Fluorescent Probe for Rapid Detection of Hydrogen Sulfide in Mitochondria

(2013) Yuncong Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Design Strategies for Water-Soluble Small Molecular Chromogenic and Fluorogenic Probes

(2013) Xiaohua Li et al.   CHEMICAL REVIEWS

Genetically Encoded Fluorescent Probe for the Selective Detection of Peroxynitrite

(2013) Zhi-jie Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Reversible Near-Infrared Fluorescent Probe Introducing Tellurium to Mimetic Glutathione Peroxidase for Monitoring the Redox Cycles between Peroxynitrite and Glutathione in Vivo

(2013) Fabiao Yu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A nanoparticle-based strategy for the imaging of a broad range of tumours by nonlinear amplification of microenvironment signals

(2013) Yiguang Wang et al.   NATURE MATERIALS

Modulation of oxidative stress as an anticancer strategy

(2013) Chiara Gorrini et al.   NATURE REVIEWS DRUG DISCOVERY

Luminescent Chemodosimeters for Bioimaging

(2012) Yuming Yang et al.   CHEMICAL REVIEWS

A Three-Channel Fluorescent Probe That Distinguishes Peroxynitrite from Hypochlorite

(2012) Quanjuan Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mechanism of Oxidative Stress in Neurodegeneration

(2012) Sonia Gandhi et al.   Oxidative Medicine and Cellular Longevity

Peroxynitrite-Induced Nitrative and Oxidative Modifications Alter Tau Filament Formation

(2011) Laurel Vana et al.   BIOCHEMISTRY

Fluorescent and luminescent probes for detection of reactive oxygen and nitrogen species

(2011) Xiaoqiang Chen et al.   CHEMICAL SOCIETY REVIEWS

A Near-IR Reversible Fluorescent Probe Modulated by Selenium for Monitoring Peroxynitrite and Imaging in Living Cells

(2011) Fabiao Yu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Hepatocyte-Targeting Single Galactose-Appended Naphthalimide: A Tool for Intracellular Thiol Imaging in Vivo

(2011) Min Hee Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chemistry and biology of reactive oxygen species in signaling or stress responses

(2011) Bryan C Dickinson et al.   Nature Chemical Biology

The immunology of stroke: from mechanisms to translation

(2011) Costantino Iadecola et al.   NATURE MEDICINE

Mechanisms of drug-induced liver injury: from bedside to bench

(2011) Shannan Tujios et al.   Nature Reviews Gastroenterology & Hepatology

In Vivo Photoacoustic Tomography of Chemicals: High-Resolution Functional and Molecular Optical Imaging at New Depths

(2010) Chulhong Kim et al.   CHEMICAL REVIEWS

Oxidative stress in early diabetic nephropathy: fueling the fire

(2010) Dhruv K. Singh et al.   Nature Reviews Endocrinology

HKGreen-3: A Rhodol-Based Fluorescent Probe for Peroxynitrite

(2010) Tao Peng et al.   ORGANIC LETTERS

Chemical Biology of Peroxynitrite: Kinetics, Diffusion, and Radicals

(2009) Gerardo Ferrer-Sueta et al.   ACS Chemical Biology

Two-Photon Absorption and the Design of Two-Photon Dyes

(2009) Miłosz Pawlicki et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Molecular Regulation of Tumor Angiogenesis and Perfusion via Redox Signaling

(2009) Thomas W. Miller et al.   CHEMICAL REVIEWS

New Strategies for Fluorescent Probe Design in Medical Diagnostic Imaging

(2009) Hisataka Kobayashi et al.   CHEMICAL REVIEWS

Current Concepts of Mechanisms in Drug-Induced Hepatotoxicity

(2009) Stefan Russmann et al.   CURRENT MEDICINAL CHEMISTRY

Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?

(2009) Dunyaporn Trachootham et al.   NATURE REVIEWS DRUG DISCOVERY

Reconciling the chemistry and biology of reactive oxygen species

(2008) Christine C Winterbourn   Nature Chemical Biology