Fluorescent probes for the simultaneous detection of multiple analytes in biology

A fluorescent turn on nanoprobe for simultaneous visualization of dual-targets involved in cell apoptosis and drug screening in living cells

(2017) Xiaolong Zhang et al.   Nanoscale

Usage of cancer associated autoantibodies in the detection of disease

(2017) Steven P. Dudas et al.   Cancer Biomarkers

Near-Infrared Fluorescence Probe for in Situ Detection of Superoxide Anion and Hydrogen Polysulfides in Mitochondrial Oxidative Stress

(2016) Yan Huang et al.   ANALYTICAL CHEMISTRY

Selective and Reversible Approaches Toward Imaging Redox Signaling Using Small-Molecule Probes

(2016) Jacek L. Kolanowski et al.   ANTIOXIDANTS & REDOX SIGNALING

A novel dual-emission fluorescent probe for the simultaneous detection of H2S and GSH

(2016) H. Li et al.   CHEMICAL COMMUNICATIONS

A dual-site two-photon fluorescent probe for visualizing lysosomes and tracking lysosomal hydrogen sulfide with two different sets of fluorescence signals in the living cells and mouse liver tissues

(2016) Yong Liu et al.   CHEMICAL COMMUNICATIONS

A fluorescent probe for relay recognition of homocysteine and Group IIIA ions including Ga(iii)

(2016) Ya-Wen Wang et al.   CHEMICAL COMMUNICATIONS

Gallium as a Therapeutic Agent: A Thermodynamic Evaluation of the Competition between Ga3+ and Fe3+ Ions in Metalloproteins

(2016) Valia Nikolova et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Real-Time Discrimination and Versatile Profiling of Spontaneous Reactive Oxygen Species in Living Organisms with a Single Fluorescent Probe

(2016) Ruilong Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Self-immolative versatile fluorogenic probes for screening of hydrolytic enzyme activity

(2016) Anna Żądło-Dobrowolska et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Monomolecular pyrenol-derivatives as multi-emissive probes for orthogonal reactivities

(2016) Björn Finkler et al.   PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

Harnessing the Potential of Small Molecule Intracellular Fluorescent Sensors

(2016) Elizabeth J. New   ACS Sensors

Recognition- and Reactivity-Based Fluorescent Probes for Studying Transition Metal Signaling in Living Systems

(2015) Allegra T. Aron et al.   ACCOUNTS OF CHEMICAL RESEARCH

A colorimetric, ratiometric and water-soluble fluorescent probe for simultaneously sensing glutathione and cysteine/homocysteine

(2015) Xi Dai et al.   ANALYTICA CHIMICA ACTA

Virginia Orange: A Versatile, Red-Shifted Fluorescein Scaffold for Single- and Dual-Input Fluorogenic Probes

(2015) Jonathan B. Grimm et al.   BIOCONJUGATE CHEMISTRY

A dual response near-infrared fluorescent probe for hydrogen polysulfides and superoxide anion detection in cells and in vivo

(2015) Fabiao Yu et al.   BIOMATERIALS

A dual-FRET-based fluorescence probe for the sequential detection of MMP-2 and caspase-3

(2015) Shi-Ying Li et al.   CHEMICAL COMMUNICATIONS

A dual FRET based fluorescent probe as a multiple logic system

(2015) Xin Zhou et al.   CHEMICAL COMMUNICATIONS

A logic gate-based fluorescent sensor for detecting H2S and NO in aqueous media and inside live cells

(2015) Peisheng Zhang et al.   CHEMICAL COMMUNICATIONS

Imaging metals in biology: balancing sensitivity, selectivity and spatial resolution

(2015) Dominic J. Hare et al.   CHEMICAL SOCIETY REVIEWS

Luminescent probes for the bioimaging of small anionic species in vitro and in vivo

(2015) Trent D. Ashton et al.   CHEMICAL SOCIETY REVIEWS

Tunable Molecular Logic Gates Designed for Imaging Released Neurotransmitters

(2015) Jessica L. Klockow et al.   CHEMISTRY-A EUROPEAN JOURNAL

Multifunctional Logic in a Photosensitizer with Triple-Mode Fluorescent and Photodynamic Activity

(2015) Eveline van de Winckel et al.   CHEMISTRY-A EUROPEAN JOURNAL

New Dual Fluorescent Probe for Simultaneous Biothiol and Phosphate Bioimaging

(2015) Sandra Resa et al.   CHEMISTRY-A EUROPEAN JOURNAL

A two fluorophore embedded probe for collective and ratiometric detection of Hg2+ and F− ions

(2015) Narendra Reddy Chereddy et al.   DYES AND PIGMENTS

“AND” luminescent “reactive” molecular logic gates: a gateway to multi-analyte bioimaging and biosensing

(2015) Anthony Romieu   ORGANIC & BIOMOLECULAR CHEMISTRY

“Double gating” – a concept for enzyme-responsive imaging probes aiming at high tissue specificity

(2014) Maxime Prost et al.   CHEMICAL COMMUNICATIONS

Redox chemistry and chemical biology of H2S, hydropersulfides, and derived species: Implications of their possible biological activity and utility

(2014) Katsuhiko Ono et al.   FREE RADICAL BIOLOGY AND MEDICINE

Principles of genetic circuit design

(2014) Jennifer A N Brophy et al.   NATURE METHODS

Hydrogen sulfide and nitric oxide interactions in inflammation

(2014) Maria Letizia Lo Faro et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

A novel rhodamine chromone-based “Off–On” chemosensor for the differential detection of Al(III) and Zn(II) in aqueous solutions

(2014) Long Fan et al.   SENSORS AND ACTUATORS B-CHEMICAL

A dual emission fluorescent probe enables simultaneous detection of glutathione and cysteine/homocysteine

(2014) Xiao-Feng Yang et al.   Chemical Science

Carbofluoresceins and Carborhodamines as Scaffolds for High-Contrast Fluorogenic Probes

(2013) Jonathan B. Grimm et al.   ACS Chemical Biology

Multi-functional fluorescent probe for Hg2+, Cu2+ and ClO− based on a pyrimidin-4-yl phenothiazine derivative

(2013) Jiena Weng et al.   ANALYST

The Power of Fluorogenic Probes

(2013) André Nadler et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Simultaneous detection of mercury(ii) and silver(i) ions with picomolar sensitivity

(2013) Guichi Zhu et al.   CHEMICAL COMMUNICATIONS

Systemic Oxidative Stress Is Associated With Lower Aerobic Capacity and Impaired Skeletal Muscle Energy Metabolism in Patients With Metabolic Syndrome

(2013) T. Yokota et al.   DIABETES CARE

Beyond H2S and NO Interplay: Hydrogen Sulfide and Nitroprusside React Directly to Give Nitroxyl (HNO). A New Pharmacological Source of HNO

(2013) Milos R. Filipovic et al.   JOURNAL OF MEDICINAL CHEMISTRY

Real-Time Phosphate Sensing in Living Cells using Fluorescence Lifetime Imaging Microscopy (FLIM)

(2013) Jose M. Paredes et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Simultaneous Fluorescence Sensing of Cys and GSH from Different Emission Channels

(2013) Jing Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chemical foundations of hydrogen sulfide biology

(2013) Qian Li et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Amplifying Genetic Logic Gates

(2013) J. Bonnet et al.   SCIENCE

A dual-responsive chromo-fluorescent probe for detection of Zn2+ and Fe3+via two different approaches

(2013) Vijay Luxami et al.   RSC Advances

Oligonucleotide-based fluorogenic sensor for simultaneous detection of heavy metal ions

(2012) Changlong Hao et al.   BIOSENSORS & BIOELECTRONICS

A robust, high-sensitivity stealth probe for peptidases

(2012) Oliver Thorn-Seshold et al.   CHEMICAL COMMUNICATIONS

Tools to study distinct metal pools in biology

(2012) Elizabeth J. New   DALTON TRANSACTIONS

Dual Targeting of Hypoxic and Acidic Tumor Environments with a Cobalt(III) Chaperone Complex

(2012) Natsuho Yamamoto et al.   JOURNAL OF MEDICINAL CHEMISTRY

Genetic programs constructed from layered logic gates in single cells

(2012) Tae Seok Moon et al.   NATURE

H2S signalling through protein sulfhydration and beyond

(2012) Bindu D. Paul et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Thiol Reactive Probes and Chemosensors

(2012) Hanjing Peng et al.   SENSORS

Simultaneous Intracellular β-d-Glucosidase and Phosphodiesterase I Activities Measurements Based on A Triple-Signaling Fluorescent Probe

(2011) Yinhui Li et al.   ANALYTICAL CHEMISTRY

Conjugate Addition/Cyclization Sequence Enables Selective and Simultaneous Fluorescence Detection of Cysteine and Homocysteine

(2011) Xiaofeng Yang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Multicolor Fluorescence of a Styrylquinoline Dye Tuned by Metal Cations

(2011) Yasuhiro Shiraishi et al.   CHEMISTRY-A EUROPEAN JOURNAL

Molecular Logic Gate Arrays

(2011) A. Prasanna de Silva   Chemistry-An Asian Journal

Single Fluorescent Probe Responds to H2O2, NO, and H2O2/NO with Three Different Sets of Fluorescence Signals

(2011) Lin Yuan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Selective, Colorimetric, and Fluorescent Chemodosimeter for Relay Recognition of Fluoride and Cyanide Anions Based on 1,1′-Binaphthyl Scaffold

(2011) Ming Dong et al.   ORGANIC LETTERS

Enzyme-mediated hydrolytic activation of prodrugs

(2011) Yan-hui Yang et al.   Acta Pharmaceutica Sinica B

Supramolecular logic with macrocyclic input and competitive reset

(2010) Uwe Pischel et al.   CHEMICAL COMMUNICATIONS

A Molecular Keypad Lock Based on the Thiacalix[4]arene of 1,3-AlternateConformation

(2009) Manoj Kumar et al.   ORGANIC LETTERS

A Multianalyte Chemosensor on a Single Molecule: Promising Structure for an Integrated Logic Gate

(2008) Mingjian Yuan et al.   JOURNAL OF ORGANIC CHEMISTRY

Prodrugs: design and clinical applications

(2008) Jarkko Rautio et al.   NATURE REVIEWS DRUG DISCOVERY