Alcoholic liver disease: mechanisms of injury and targeted treatment
Published 2015 View Full Article
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Title
Alcoholic liver disease: mechanisms of injury and targeted treatment
Authors
Keywords
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Journal
Nature Reviews Gastroenterology & Hepatology
Volume 12, Issue 4, Pages 231-242
Publisher
Springer Nature
Online
2015-03-17
DOI
10.1038/nrgastro.2015.35
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Note: Only part of the references are listed.- Supplementation of Saturated Long-Chain Fatty Acids Maintains Intestinal Eubiosis and Reduces Ethanol-induced Liver Injury in Mice
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- (2014) Bernd Schnabl et al. GASTROENTEROLOGY
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- (2014) Silvia Affò et al. GUT
- Pentoxifylline vs. corticosteroid to treat severe alcoholic hepatitis: A randomised, non-inferiority, open trial
- (2014) Seung Ha Park et al. JOURNAL OF HEPATOLOGY
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- (2014) Giulia Malaguarnera WORLD JOURNAL OF GASTROENTEROLOGY
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- (2013) Timothy Hardy et al. BMC GASTROENTEROLOGY
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- (2013) Huquan Yin et al. GASTROENTEROLOGY
- Human and experimental evidence supporting a role for osteopontin in alcoholic hepatitis
- (2013) Oriol Morales-Ibanez et al. HEPATOLOGY
- Loss of caspase-8 in hepatocytes accelerates the onset of liver regeneration in mice through premature nuclear factor kappa B activation
- (2013) Julia Freimuth et al. HEPATOLOGY
- M2 Kupffer cells promote M1 Kupffer cell apoptosis: A protective mechanism against alcoholic and nonalcoholic fatty liver disease
- (2013) Jinghong Wan et al. HEPATOLOGY
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- (2013) Philippe Mathurin et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
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- (2012) Rachael P. Dippold et al. ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH
- Autophagy in Alcohol-Induced Liver Diseases
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- Alcohol Metabolism
- (2012) Arthur I. Cederbaum Clinics in Liver Disease
- Corticosteroid Plus Pentoxifylline Is Not Better than Corticosteroid Alone for Improving Survival in Severe Alcoholic Hepatitis (COPE Trial)
- (2012) Sandeep Singh Sidhu et al. DIGESTIVE DISEASES AND SCIENCES
- Transcriptome analysis identifies TNF superfamily receptors as potential therapeutic targets in alcoholic hepatitis
- (2012) Silvia Affò et al. GUT
- Interstrain differences in liver injury and one-carbon metabolism in alcohol-fed mice
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- (2012) Pau Sancho-Bru et al. HEPATOLOGY
- Macrophage migration inhibitory factor contributes to ethanol-induced liver injury by mediating cell injury, steatohepatitis, and steatosis
- (2012) Mark A. Barnes et al. HEPATOLOGY
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- (2012) Winston Dunn et al. JOURNAL OF HEPATOLOGY
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- (2011) Rajeshwar P. Mookerjee et al. JOURNAL OF HEPATOLOGY
- Targeting gut microbiota in obesity: effects of prebiotics and probiotics
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- Alcoholic Liver Disease
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- (2009) Marlene Dominguez et al. GASTROENTEROLOGY
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- (2009) Thierry Gustot et al. HEPATOLOGY
- Liver regeneration: Alternative epithelial pathways
- (2009) George K. Michalopoulos INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Alcoholic Hepatitis
- (2009) Michael R. Lucey et al. NEW ENGLAND JOURNAL OF MEDICINE
- Pentoxifylline versus prednisolone for severe alcoholic hepatitis: A randomized controlled trial
- (2009) Binay Krishna De et al. WORLD JOURNAL OF GASTROENTEROLOGY
- Probiotics restore bowel flora and improve liver enzymes in human alcohol-induced liver injury: a pilot study
- (2008) Irina A. Kirpich et al. ALCOHOL
- A Recent Perspective on Alcohol, Immunity, and Host Defense
- (2008) Gyongyi Szabo et al. ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH
- A New Scoring System for Prognostic Stratification of Patients With Alcoholic Hepatitis
- (2008) Marlene Dominguez et al. AMERICAN JOURNAL OF GASTROENTEROLOGY
- H9c2 cardiomyoblasts produce thyroid hormone
- (2008) Christof Meischl et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Alcohol—intoxicating roadblocks and bottlenecks in hepatic protein and lipid metabolism
- (2008) Patricia E. Molina AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Paracrine Activation of Hepatic CB1 Receptors by Stellate Cell-Derived Endocannabinoids Mediates Alcoholic Fatty Liver
- (2008) Won-il Jeong et al. Cell Metabolism
- A Randomized, Double-Blinded, Placebo-Controlled Multicenter Trial of Etanercept in the Treatment of Alcoholic Hepatitis
- (2008) Nicholas C. Boetticher et al. GASTROENTEROLOGY
- Accumulation of Hedgehog-Responsive Progenitors Parallels Alcoholic Liver Disease Severity in Mice and Humans
- (2008) Youngmi Jung et al. GASTROENTEROLOGY
- An inducible autocrine cascade regulates rat hepatocyte proliferation and apoptosis responses to tumor necrosis factor-α
- (2008) Benjamin D. Cosgrove et al. HEPATOLOGY
- The critical role of toll-like receptor (TLR) 4 in alcoholic liver disease is independent of the common TLR adapter MyD88
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- Dissection of endoplasmic reticulum stress signaling in alcoholic and non-alcoholic liver injury
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- Effect of probiotic treatment on deranged neutrophil function and cytokine responses in patients with compensated alcoholic cirrhosis
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- Infliximab monotherapy for severe alcoholic hepatitis and predictors of survival: An open label trial
- (2008) Praveen Sharma et al. JOURNAL OF HEPATOLOGY
- Discovery and Development of Toll-Like Receptor 4 (TLR4) Antagonists: A New Paradigm for Treating Sepsis and Other Diseases
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- Ethanol consumption impairs regulation of fatty acid metabolism by decreasing the activity of AMP-activated protein kinase in rat liver
- (2007) Javier García-Villafranca et al. BIOCHIMIE
- CYP2E1 and oxidative liver injury by alcohol
- (2007) Yongke Lu et al. FREE RADICAL BIOLOGY AND MEDICINE
- Early switch to pentoxifylline in patients with severe alcoholic hepatitis is inefficient in non-responders to corticosteroids
- (2007) Alexandre Louvet et al. JOURNAL OF HEPATOLOGY
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