Mechanisms of drug-induced liver injury: from bedside to bench

Important Elements for the Diagnosis of Drug-Induced Liver Injury

(2010) Vijay K. Agarwal et al.   Clinical Gastroenterology and Hepatology

Mitochondrial superoxide dismutase and glutathione peroxidase in idiosyncratic drug-induced liver injury

(2010) M. Isabel Lucena et al.   HEPATOLOGY

Mitochondrial and immunoallergic injury increase risk of positive drug rechallenge after drug-induced liver injury: A systematic review

(2010) Christine M. Hunt   HEPATOLOGY

Standardization of nomenclature and causality assessment in drug-induced liver injury: Summary of a clinical research workshop

(2010) Robert J. Fontana et al.   HEPATOLOGY

A role for the pregnane X receptor in flucloxacillin-induced liver injury

(2010) Elise Andrews et al.   HEPATOLOGY

Polymerase γ Gene POLG determines the risk of sodium valproate-induced liver toxicity

(2010) Joanna D. Stewart et al.   HEPATOLOGY

A genome-wide study identifies HLA alleles associated with lumiracoxib-related liver injury

(2010) Jonathan B Singer et al.   NATURE GENETICS

Cheminformatics Analysis of Assertions Mined from Literature That Describe Drug-Induced Liver Injury in Different Species

(2009) Denis Fourches et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Pharmacokinetics of Acetaminophen-Protein Adducts in Adults with Acetaminophen Overdose and Acute Liver Failure

(2009) L. P. James et al.   DRUG METABOLISM AND DISPOSITION

S1590 Immuno-Allergic (I-a) Manifestations of Drug-Induced Liver Injury (DILI) in the USA. Results from the Prospective Study of the DILI Network

(2009) Herbert L. Bonkovsky et al.   GASTROENTEROLOGY

Mouse population-guided resequencing reveals that variants in CD44 contribute to acetaminophen-induced liver injury in humans

(2009) A. H. Harrill et al.   GENOME RESEARCH

Expression of organic cation transporters OCT1 (SLC22A1) and OCT3 (SLC22A3) is affected by genetic factors and cholestasis in human liver

(2009) Anne T. Nies et al.   HEPATOLOGY

Acetaminophen dosing of humans results in blood transcriptome and metabolome changes consistent with impaired oxidative phosphorylation

(2009) Rick D. Fannin et al.   HEPATOLOGY

Liver disease associated with canalicular transport defects: Current and future therapies

(2009) Janneke M. Stapelbroek et al.   JOURNAL OF HEPATOLOGY

HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin

(2009) Ann K Daly et al.   NATURE GENETICS

Case series of liver failure associated with rosiglitazone and pioglitazone

(2009) James S. Floyd et al.   PHARMACOEPIDEMIOLOGY AND DRUG SAFETY

Drug-induced liver injury following positive drug rechallenge

(2009) Julie I. Papay et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Identification of structure–activity relationships for adverse effects of pharmaceuticals in humans: Part C: Use of QSAR and an expert system for the estimation of the mechanism of action of drug-induced hepatobiliary and urinary tract toxicities

(2009) Edwin J. Matthews et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Biomarkers for the Diagnosis and Management of Drug-Induced Liver Injury

(2009) Paul Watkins   SEMINARS IN LIVER DISEASE

Immunoallergic Drug-Induced Liver Injury in Humans

(2009) Jack Uetrecht   SEMINARS IN LIVER DISEASE

Role of Mitochondria in Drug-Induced Cholestatic Injury

(2008) George E.N. Kass et al.   Clinics in Liver Disease

Causes, Clinical Features, and Outcomes From a Prospective Study of Drug-Induced Liver Injury in the United States

(2008) Naga Chalasani et al.   GASTROENTEROLOGY

Relationship between daily dose of oral medications and idiosyncratic drug-induced liver injury: Search for signals

(2008) Craig Lammert et al.   HEPATOLOGY

Critical role of CD44 in hepatotoxin-mediated liver injury

(2008) Kiminori Kimura et al.   JOURNAL OF HEPATOLOGY