The entry of nanoparticles into solid tumours

Extravasating Neutrophils Open Vascular Barrier and Improve Liposomes Delivery to Tumors

(2019) Victor A. Naumenko et al.   ACS Nano

Quantifying the Ligand-Coated Nanoparticle Delivery to Cancer Cells in Solid Tumours

(2018) Qin Dai et al.   ACS Nano

Progress and challenges towards targeted delivery of cancer therapeutics

(2018) Daniel Rosenblum et al.   Nature Communications

Influence of protein corona and caveolae-mediated endocytosis on nanoparticle uptake and transcytosis

(2018) Yan Teck Ho et al.   Nanoscale

Overcoming key biological barriers to cancer drug delivery and efficacy

(2017) Susy M. Kim et al.   JOURNAL OF CONTROLLED RELEASE

Three-Dimensional Imaging of Transparent Tissues via Metal Nanoparticle Labeling

(2017) Abdullah Muhammad Syed et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Effect of removing Kupffer cells on nanoparticle tumor delivery

(2017) Anthony J. Tavares et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Three-Dimensional Optical Mapping of Nanoparticle Distribution in Intact Tissues

(2016) Shrey Sindhwani et al.   ACS Nano

Exploring Passive Clearing for 3D Optical Imaging of Nanoparticles in Intact Tissues

(2016) Shrey Sindhwani et al.   BIOCONJUGATE CHEMISTRY

Nanodrug Delivery: Is the Enhanced Permeability and Retention Effect Sufficient for Curing Cancer?

(2016) Yuko Nakamura et al.   BIOCONJUGATE CHEMISTRY

To exploit the tumor microenvironment: Since the EPR effect fails in the clinic, what is the future of nanomedicine?

(2016) F. Danhier   JOURNAL OF CONTROLLED RELEASE

Vascular bursts enhance permeability of tumour blood vessels and improve nanoparticle delivery

(2016) Yu Matsumoto et al.   Nature Nanotechnology

Tailoring nanoparticle designs to target cancer based on tumor pathophysiology

(2016) Edward A. Sykes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Analysis of nanoparticle delivery to tumours

(2016) Stefan Wilhelm et al.   Nature Reviews Materials

Cancer nanomedicine: addressing the dark side of the enhanced permeability and retention effect

(2015) Elizabeth Huynh et al.   Nanomedicine

Real-Time Imaging Reveals Local, Transient Vascular Permeability, and Tumor Cell Intravasation Stimulated by TIE2hi Macrophage-Derived VEGFA

(2015) A. S. Harney et al.   Cancer Discovery

Investigating the Impact of Nanoparticle Size on Active and Passive Tumor Targeting Efficiency

(2014) Edward A. Sykes et al.   ACS Nano

Development of next-generation macromolecular drugs based on the EPR effect: challenges and pitfalls

(2014) Hideaki Nakamura et al.   Expert Opinion on Drug Delivery

EPR: Evidence and fallacy

(2014) Joseph W. Nichols et al.   JOURNAL OF CONTROLLED RELEASE

In vivo proteomic imaging analysis of caveolae reveals pumping system to penetrate solid tumors

(2014) Phil Oh et al.   NATURE MEDICINE

Differential uptake of nanoparticles by endothelial cells through polyelectrolytes with affinity for caveolae

(2014) J. Voigt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Imaging Tumor-Stroma Interactions during Chemotherapy Reveals Contributions of the Microenvironment to Resistance

(2012) Elizabeth S. Nakasone et al.   CANCER CELL

The Diaphragms of Fenestrated Endothelia: Gatekeepers of Vascular Permeability and Blood Composition

(2012) Radu V. Stan et al.   DEVELOPMENTAL CELL

Normalization of tumour blood vessels improves the delivery of nanomedicines in a size-dependent manner

(2012) Vikash P. Chauhan et al.   Nature Nanotechnology

Caveolae, Fenestrae and Transendothelial Channels Retain PV1 on the Surface of Endothelial Cells

(2012) Eugene Tkachenko et al.   PLoS One

Fluorescence-Tagged Gold Nanoparticles for Rapidly Characterizing the Size-Dependent Biodistribution in Tumor Models

(2012) Leo Y. T. Chou et al.   Advanced Healthcare Materials

Delivering nanomedicine to solid tumors

(2010) Rakesh K. Jain et al.   Nature Reviews Clinical Oncology

Synthesis and Surface Modification of Highly Monodispersed, Spherical Gold Nanoparticles of 50−200 nm

(2009) Steven D. Perrault et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Visualizing stromal cell dynamics in different tumor microenvironments by spinning disk confocal microscopy

(2008) M. Egeblad et al.   Disease Models & Mechanisms