The Role of RBC Oxidative Stress in Sickle Cell Disease: From the Molecular Basis to Pathologic Implications

Mn porphyrins as a novel treatment targeting sickle cell NOXs to reverse and prevent acute vaso-occlusion in vivo

(2020) Madhan Thamilarasan et al.   Blood Advances

Disrupting the vicious cycle created by NOX activation in sickle erythrocytes exposed to hypoxia/reoxygenation prevents adhesion and vasoocclusion

(2019) Anson MacKinney et al.   Redox Biology

Thiol regulation by Mn porphyrins, commonly known as SOD mimics

(2019) Ines Batinic-Haberle et al.   Redox Biology

P-selectin drives complement attack on endothelium during intravascular hemolysis in TLR-4/heme-dependent manner

(2019) Nicolas S. Merle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hydroxyurea Reverses Dysfunctional Ubiquitin-Proteasomal System in Sickle CELL Disease and Suppresses Posttranslational Alterations in Hemoglobin and CELL Membranes

(2019) Swee Lay Thein et al.   BLOOD

BMX-001, a novel redox-active metalloporphyrin, improves islet function and engraftment in a murine transplant model

(2018) Antonio Bruni et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Mn porphyrin-based redox-active drugs – Differential effects as cancer therapeutics and protectors of normal tissue against oxidative injury

(2018) Ines Batinic-Haberle et al.   ANTIOXIDANTS & REDOX SIGNALING

Radiation-Mediated Tumor Growth Inhibition Is Significantly Enhanced with Redox-Active Compounds That Cycle with Ascorbate

(2018) Artak Tovmasyan et al.   ANTIOXIDANTS & REDOX SIGNALING

Oxidative pathways in the sickle cell and beyond

(2018) Abdu I. Alayash   BLOOD CELLS MOLECULES AND DISEASES

Oxidative stress, eryptosis and anemia: A pivotal mechanistic nexus in systemic diseases

(2018) Rosi Bissinger et al.   FEBS Journal

A Phase 3 Trial of l-Glutamine in Sickle Cell Disease

(2018) Yutaka Niihara et al.   NEW ENGLAND JOURNAL OF MEDICINE

Role of l -amino acid oxidase isolated from Calloselasma rhodostoma venom on neutrophil NADPH oxidase complex activation

(2018) Mauro Valentino Paloschi et al.   TOXICON

Platelet-RBC interaction mediated by FasL/FasR induces procoagulant activity important for thrombosis

(2018) Christoph Klatt et al.   JOURNAL OF CLINICAL INVESTIGATION

Simultaneous polymerization and adhesion under hypoxia in sickle cell disease

(2018) Dimitrios P. Papageorgiou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Critical role of C5a in sickle cell disease

(2018) Gregory M. Vercellotti et al.   AMERICAN JOURNAL OF HEMATOLOGY

Advances in the Treatment of Sickle Cell Disease

(2018) Sargam Kapoor et al.   MAYO CLINIC PROCEEDINGS

Therapeutic strategies for sickle cell disease: towards a multi-agent approach

(2018) Marilyn J. Telen et al.   NATURE REVIEWS DRUG DISCOVERY

Hydroxyurea therapy modulates sickle cell anemia red blood cell physiology: Impact on RBC deformability, oxidative stress, nitrite levels and nitric oxide synthase signalling pathway

(2018) Elie Nader et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Pharmacological inhibition of LSD1 and mTOR reduces mitochondrial retention and associated ROS levels in the red blood cells of sickle cell disease

(2017) Ramasamy Jagadeeswaran et al.   EXPERIMENTAL HEMATOLOGY

Brain neurochemical and hemodynamic findings in the NY1DD mouse model of mild sickle cell disease

(2017) Min-Hui Cui et al.   NMR IN BIOMEDICINE

A novel redox regulator, MnTnBuOE-2-PyP 5+ , enhances normal hematopoietic stem/progenitor cell function

(2017) Y. Zhao et al.   Redox Biology

The ins and outs of reticulocyte maturation revisited: The role of autophagy in sickle cell disease

(2016) Tosti J. Mankelow et al.   Autophagy

Deoxygenation Reduces Sickle Cell Blood Flow at Arterial Oxygen Tension

(2016) Xinran Lu et al.   BIOPHYSICAL JOURNAL

Coagulation abnormalities of sickle cell disease: Relationship with clinical outcomes and the effect of disease modifying therapies

(2016) Denis Noubouossie et al.   BLOOD REVIEWS

Exacerbation of oxidative stress during sickle vaso-occlusive crisis is associated with decreased anti-band 3 autoantibodies rate and increased red blood cell-derived microparticle level: a prospective study

(2016) Régine Hierso et al.   BRITISH JOURNAL OF HAEMATOLOGY

The role of complement activation in thrombosis and hemolytic anemias

(2016) John Chapin et al.   TRANSFUSION AND APHERESIS SCIENCE

A novel redox-active metalloporphyrin reduces reactive oxygen species and inflammatory markers but does not improve marginal mass engraftment in a murine donation after circulatory death islet transplantation model

(2016) Antonio Bruni et al.   Islets

The delay time in sickle cell disease after 40 years: A paradigm assessed

(2015) Frank A. Ferrone   AMERICAN JOURNAL OF HEMATOLOGY

Circulating cell membrane microparticles transfer heme to endothelial cells and trigger vasoocclusions in sickle cell disease

(2015) S. M. Camus et al.   BLOOD

Glutathione peroxidase 4 prevents necroptosis in mouse erythroid precursors

(2015) O. Canli et al.   BLOOD

Anticancer therapeutic potential of Mn porphyrin/ascorbate system

(2015) Artak Tovmasyan et al.   FREE RADICAL BIOLOGY AND MEDICINE

Manganese (III) meso-tetrakis N-ethylpyridinium-2-yl porphyrin acts as a pro-oxidant to inhibit electron transport chain proteins, modulate bioenergetics, and enhance the response to chemotherapy in lymphoma cells

(2015) Melba C. Jaramillo et al.   FREE RADICAL BIOLOGY AND MEDICINE

Gαs proteins activate p72Syk and p60-c-Src tyrosine kinases to mediate sickle red blood cell adhesion to endothelium via LW-αvβ3 and CD44–CD44 interactions

(2015) Edward Chiou et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Hemolysate-mediated platelet aggregation: an additional risk mechanism contributing to thrombosis of continuous flow ventricular assist devices

(2015) Phat L Tran et al.   PERFUSION-UK

The pathophysiology of extracellular hemoglobin associated with enhanced oxidative reactions

(2015) Joseph M. Rifkind et al.   Frontiers in Physiology

Complement-Coagulation Cross-Talk: A Potential Mediator of the Physiological Activation of Complement by Low pH

(2015) Hany Ibrahim Kenawy et al.   Frontiers in Immunology

Calcium and ROS: A mutual interplay

(2015) Agnes Görlach et al.   Redox Biology

Toll-like receptor 2/4 heterodimer mediates inflammatory injury in intracerebral hemorrhage

(2014) Yan-Chun Wang et al.   ANNALS OF NEUROLOGY

Molecular mechanisms underlying synergistic adhesion of sickle red blood cells by hypoxia and low nitric oxide bioavailability

(2014) D. R. Gutsaeva et al.   BLOOD

Sickle cell disease increases high mobility group box 1: a novel mechanism of inflammation

(2014) H. Xu et al.   BLOOD

Hemolysis is a primary ATP-release mechanism in human erythrocytes

(2014) J. Sikora et al.   BLOOD

Extracellular nucleotide and nucleoside signaling in vascular and blood disease

(2014) M. Idzko et al.   BLOOD

Heme-induced neutrophil extracellular traps contribute to the pathogenesis of sickle cell disease

(2014) G. Chen et al.   BLOOD

Role of the Hemostatic System on Sickle Cell Disease Pathophysiology and Potential Therapeutics

(2014) Zahra Pakbaz et al.   HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA

Factor XIII activity mediates red blood cell retention in venous thrombi

(2014) Maria M. Aleman et al.   JOURNAL OF CLINICAL INVESTIGATION

Histones induce phosphatidylserine exposure and a procoagulant phenotype in human red blood cells

(2014) F. Semeraro et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Red blood cell oxidative stress impairs oxygen delivery and induces red blood cell aging

(2014) Joy G. Mohanty et al.   Frontiers in Physiology

N-methyl-d-aspartate receptors in human erythroid precursor cells and in circulating red blood cells contribute to the intracellular calcium regulation

(2013) Asya Makhro et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

HMGB1 promotes neutrophil extracellular trap formation through interactions with Toll-like receptor 4

(2013) Jean-Marc Tadie et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

SOD Therapeutics: Latest Insights into Their Structure-Activity Relationships and Impact on the Cellular Redox-Based Signaling Pathways

(2013) Ines Batinic-Haberle et al.   ANTIOXIDANTS & REDOX SIGNALING

Biomarkers of lipid peroxidation in clinical material

(2013) Etsuo Niki   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Erythrocyte NADPH oxidase activity modulated by Rac GTPases, PKC, and plasma cytokines contributes to oxidative stress in sickle cell disease

(2013) A. George et al.   BLOOD

Red blood cells mediate the onset of thrombosis in the ferric chloride murine model

(2013) J. D. Barr et al.   BLOOD

Sickle cell vaso-occlusion causes activation of iNKT cells that is decreased by the adenosine A2A receptor agonist regadenoson

(2013) J. J. Field et al.   BLOOD

Complement activation by heme as a secondary hit for atypical hemolytic uremic syndrome

(2013) M. Frimat et al.   BLOOD

Heme triggers TLR4 signaling leading to endothelial cell activation and vaso-occlusion in murine sickle cell disease

(2013) J. D. Belcher et al.   BLOOD

New insights provided by a comparison of impaired deformability with erythrocyte oxidative stress for sickle cell disease

(2013) Viachaslau M. Barodka et al.   BLOOD CELLS MOLECULES AND DISEASES

Oxidative stress in sickle cell disease: An overview of erythrocyte redox metabolism and current antioxidant therapeutic strategies

(2013) Danilo Grunig Humberto Silva et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mn porphyrin in combination with ascorbate acts as a pro-oxidant and mediates caspase-independent cancer cell death

(2013) Myron K. Evans et al.   FREE RADICAL BIOLOGY AND MEDICINE

Inborn defects in the antioxidant systems of human red blood cells

(2013) Rob van Zwieten et al.   FREE RADICAL BIOLOGY AND MEDICINE

Large scale simulation of red blood cell aggregation in shear flows

(2013) Dong Xu et al.   JOURNAL OF BIOMECHANICS

Extracellular hemin crisis triggers acute chest syndrome in sickle mice

(2013) Samit Ghosh et al.   JOURNAL OF CLINICAL INVESTIGATION

Whey Protein Inhibits Iron Overload-Induced Oxidative Stress in Rats

(2013) Jungmi KIM et al.   JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY

Oxidative Stress andβ-Thalassemic Erythroid Cells behind the Molecular Defect

(2013) Lucia De Franceschi et al.   Oxidative Medicine and Cellular Longevity

Identification of the Ca2+ entry pathway involved in deoxygenation-induced phosphatidylserine exposure in red blood cells from patients with sickle cell disease

(2013) U. M. Cytlak et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Increased Reticulocytosis during Infancy Is Associated with Increased Hospitalizations in Sickle Cell Anemia Patients during the First Three Years of Life

(2013) Emily Riehm Meier et al.   PLoS One

Sildenafil Citrate-Restored eNOS and PDE5 Regulation in Sickle Cell Mouse Penis Prevents Priapism Via Control of Oxidative/Nitrosative Stress

(2013) Trinity J. Bivalacqua et al.   PLoS One

Extracellular haemoglobin upregulates and binds to tissue factor on macrophages: Implications for coagulation and oxidative stress

(2013) N. Bahl et al.   THROMBOSIS AND HAEMOSTASIS

Nitroprusside inhibits calcium-induced impairment of red blood cell deformability

(2013) Viachaslau Barodka et al.   TRANSFUSION

Interaction of aldehydes derived from lipid peroxidation and membrane proteins

(2013) Stefania Pizzimenti et al.   Frontiers in Physiology

N-acetylcysteine reduces oxidative stress in sickle cell patients

(2012) Erfan Nur et al.   ANNALS OF HEMATOLOGY

Peroxiredoxin II is essential for preventing hemolytic anemia from oxidative stress through maintaining hemoglobin stability

(2012) Ying-Hao Han et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Identification of Contact Sites between Ankyrin and Band 3 in the Human Erythrocyte Membrane

(2012) Jesse L. Grey et al.   BIOCHEMISTRY

Erythrocyte microparticles can induce kidney vaso-occlusions in a murine model of sickle cell disease

(2012) S. M. Camus et al.   BLOOD

Prothrombin activation in blood coagulation: the erythrocyte contribution to thrombin generation

(2012) M. F. Whelihan et al.   BLOOD

Hemolysis and free hemoglobin revisited: exploring hemoglobin and hemin scavengers as a novel class of therapeutic proteins

(2012) D. J. Schaer et al.   BLOOD

Mitochondrial dysfunction and oxidative stress activate inflammasomes: impact on the aging process and age-related diseases

(2012) Antero Salminen et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Effect of Propranolol as Antiadhesive Therapy in Sickle Cell Disease

(2012) Laura M. De Castro et al.   CTS-Clinical and Translational Science

Manganese Porphyrin, MnTE-2-PyP5+, Acts as a Pro-Oxidant to Potentiate Glucocorticoid-Induced Apoptosis in Lymphoma Cells

(2012) Melba C. Jaramillo et al.   FREE RADICAL BIOLOGY AND MEDICINE

Role of peroxiredoxin-2 in protecting RBCs from hydrogen peroxide-induced oxidative stress

(2012) E. Nagababu et al.   FREE RADICAL RESEARCH

Reactive Oxygen Species in Health and Disease

(2012) Assim A. Alfadda et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Monocytes, neutrophils, and platelets cooperate to initiate and propagate venous thrombosis in mice in vivo

(2012) Marie-Luise von Brühl et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Targeting NADPH Oxidase Decreases Oxidative Stress in the Transgenic Sickle Cell Mouse Penis

(2012) Biljana Musicki et al.   Journal of Sexual Medicine

Platelet- and erythrocyte-derived microparticles trigger thrombin generation via factor XIIa

(2012) P. E. J. VAN DER MEIJDEN et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Global epidemiology of sickle haemoglobin in neonates: a contemporary geostatistical model-based map and population estimates

(2012) Frédéric B Piel et al.   LANCET

Citrulline and arginine utility in treating nitric oxide deficiency in mitochondrial disorders

(2012) Ayman W. El-Hattab et al.   MOLECULAR GENETICS AND METABOLISM

Procoagulant activity of erythrocytes and platelets through phosphatidylserine exposure and microparticles release in patients with nephrotic syndrome

(2012) Chunyan Gao et al.   THROMBOSIS AND HAEMOSTASIS

Red blood cell-derived microparticles isolated from blood units initiate and propagate thrombin generation

(2012) Olivier Rubin et al.   TRANSFUSION

Low-shear red blood cell oxygen transport effectiveness is adversely affected by transfusion and further worsened by deoxygenation in sickle cell disease patients on chronic transfusion therapy

(2012) Jon Detterich et al.   TRANSFUSION

Oxidative stress in sickle cell disease; pathophysiology and potential implications for disease management

(2011) Erfan Nur et al.   AMERICAN JOURNAL OF HEMATOLOGY

Leukocytes and the Natural History of Deep Vein Thrombosis

(2011) Prakash Saha et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Integrin-associated protein (CD47) is a putative mediator for soluble fibrinogen interaction with human red blood cells membrane

(2011) S. De Oliveira et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Lysophosphatidic acid induced red blood cell aggregation in vitro

(2011) Lars Kaestner et al.   BIOELECTROCHEMISTRY

Platelet Adhesion from Shear Blood Flow Is Controlled by Near-Wall Rebounding Collisions with Erythrocytes

(2011) A.A. Tokarev et al.   BIOPHYSICAL JOURNAL

Erythrocyte plasma membrane-bound ERK1/2 activation promotes ICAM-4-mediated sickle red cell adhesion to endothelium

(2011) R. Zennadi et al.   BLOOD

Regulation of membrane-cytoskeletal interactions by tyrosine phosphorylation of erythrocyte band 3

(2011) E. Ferru et al.   BLOOD

Relationship between oxidative stress, glutathione S-transferase polymorphisms and hydroxyurea treatment in sickle cell anemia

(2011) Danilo Grünig Humberto Silva et al.   BLOOD CELLS MOLECULES AND DISEASES

Assessment of oxidative stress in patients with sickle cell disease: The glutathione system and the oxidant–antioxidant status

(2011) Anna Gizi et al.   BLOOD CELLS MOLECULES AND DISEASES

Nitric oxide/cGMP pathway signaling actively down-regulates α4β1-integrin affinity: an unexpected mechanism for inducing cell de-adhesion

(2011) Alexandre Chigaev et al.   BMC IMMUNOLOGY

Stimulation of human red blood cells leads to Ca2+-mediated intercellular adhesion

(2011) Patrick Steffen et al.   CELL CALCIUM

Mitochondrial ROS fuel the inflammasome

(2011) Matthew T Sorbara et al.   CELL RESEARCH

Biomarkers of Inflammation, Growth Factor, and Coagulation Activation in Patients With Sickle Cell Disease

(2011) M. H. Qari et al.   CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS

Neuroprotective Efficacy from a Lipophilic Redox-Modulating Mn(III) N-Hexylpyridylporphyrin, MnTnHex-2-PyP: Rodent Models of Ischemic Stroke and Subarachnoid Hemorrhage

(2011) H. Sheng et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Red blood cell phosphatidylserine exposure is responsible for increased erythrocyte adhesion to endothelium in central retinal vein occlusion

(2011) M.-P. WAUTIER et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

NADPH oxidase inhibition attenuates total body irradiation-induced haematopoietic genomic instability

(2011) S. K. Pazhanisamy et al.   MUTAGENESIS

Microvesicles are messengers

(2011) Jürg A. Schifferli   Seminars in Immunopathology

Atomic Force Microscopy-Based Molecular Recognition of a Fibrinogen Receptor on Human Erythrocytes

(2010) Filomena A. Carvalho et al.   ACS Nano

Severe sickle cell anemia is associated with increased plasma levels of TNF-R1 and VCAM-1

(2010) Daniel A. Dworkis et al.   AMERICAN JOURNAL OF HEMATOLOGY

Superoxide Dismutase Mimics: Chemistry, Pharmacology, and Therapeutic Potential

(2010) Ines Batinić-Haberle et al.   ANTIOXIDANTS & REDOX SIGNALING

Adenosine A2A receptors induced on iNKT and NK cells reduce pulmonary inflammation and injury in mice with sickle cell disease

(2010) K. L. Wallace et al.   BLOOD

Altered phosphorylation of cytoskeleton proteins in sickle red blood cells: The role of protein kinase C, Rac GTPases, and reactive oxygen species

(2010) Alex George et al.   BLOOD CELLS MOLECULES AND DISEASES

Oxidative stress status, clinical outcome, and β-globin gene cluster haplotypes in pediatric patients with sickle cell disease

(2010) Iryna Rusanova et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

Aggregation of mononuclear and red blood cells through an  4 1-Lu/basal cell adhesion molecule interaction in sickle cell disease

(2010) V. Chaar et al.   HAEMATOLOGICA

Sickle cell disease serum induces NADPH enzyme subunit expression and oxidant production in leukocytes

(2010) Camila B. Almeida et al.   Hematology

Sickle-cell disease

(2010) David C Rees et al.   LANCET

A role for mitochondria in NLRP3 inflammasome activation

(2010) Rongbin Zhou et al.   NATURE

Extracellular DNA traps promote thrombosis

(2010) T. A. Fuchs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Global distribution of the sickle cell gene and geographical confirmation of the malaria hypothesis

(2010) Frédéric B. Piel et al.   Nature Communications

Plasma annexin A5 and microparticle phosphatidylserine levels are elevated in sickle cell disease and increase further during painful crisis

(2009) L.J. van Tits et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

NKT cells mediate pulmonary inflammation and dysfunction in murine sickle cell disease through production of IFN-  and CXCR3 chemokines

(2009) K. L. Wallace et al.   BLOOD

Long-term neuroprotection from a potent redox-modulating metalloporphyrin in the rat

(2009) Huaxin Sheng et al.   FREE RADICAL BIOLOGY AND MEDICINE

Red blood cell aggregation, aggregate strength and oxygen transport potential of blood are abnormal in both homozygous sickle cell anemia and sickle-hemoglobin C disease

(2009) J. Tripette et al.   HAEMATOLOGICA

Circulating erythrocyte-derived microparticles are associated with coagulation activation in sickle cell disease

(2009) E. J. van Beers et al.   HAEMATOLOGICA

Newer Aspects of the Pathophysiology of Sickle Cell Disease Vaso-Occlusion

(2009) Nicola Conran et al.   HEMOGLOBIN

Erythrocyte Hemolysis and Hemoglobin Oxidation Promote Ferric Chloride-induced Vascular Injury

(2009) Kevin J. Woollard et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Modulation of Erythrocyte Acetylcholinesterase Activity and Its Association with G Protein-Band 3 Interactions

(2009) F. A. Carvalho et al.   JOURNAL OF MEMBRANE BIOLOGY

Loss of autophagy in erythroid cells leads to defective removal of mitochondria and severe anemia in vivo

(2009) M. Mortensen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Induction of Heme Oxygenase-1 is a Beneficial Response in a Murine Model of Venous Thrombosis

(2008) Michal J. Tracz et al.   AMERICAN JOURNAL OF PATHOLOGY

Sickle red cells induce adhesion of lymphocytes and monocytes to endothelium

(2008) R. Zennadi et al.   BLOOD

Fibronectin bridges monocytes and reticulocytes via integrin α4β1

(2008) Julia E. Brittain et al.   BRITISH JOURNAL OF HAEMATOLOGY

Microvesicles in haemoglobinopathies offer insights into mechanisms of hypercoagulability, haemolysis and the effects of therapy

(2008) Maxwell Westerman et al.   BRITISH JOURNAL OF HAEMATOLOGY

Erythrocyte vesiculation: a self-protective mechanism?

(2008) Frans L. A. Willekens et al.   BRITISH JOURNAL OF HAEMATOLOGY

Modulation of redox pathways in neutrophils from sickle cell disease patients

(2008) Mutay Aslan et al.   EXPERIMENTAL HEMATOLOGY

Patients with Sickle Cell Disease have Reduced Blood Antioxidant Protection

(2008) Ren et al.   INTERNATIONAL JOURNAL FOR VITAMIN AND NUTRITION RESEARCH

Genetic variation in heme oxygenase 1 (HMOX1) and the risk of recurrent venous thromboembolism

(2008) Stefan Mustafa et al.   JOURNAL OF VASCULAR SURGERY

Microglial clearance function in health and disease

(2008) I. Napoli et al.   NEUROSCIENCE

Lipoic acid and acetyl-carnitine reverse iron-induced oxidative stress in human fibroblasts

(2008) Ashutosh Lal et al.   REDOX REPORT

Possible mechanisms contributing to oxidative inactivation of activated protein C: Molecular dynamics study

(2008) Armen Nalian et al.   THROMBOSIS AND HAEMOSTASIS

Phosphatidylserine-positive erythrocytes bind to immobilized and soluble thrombospondin-1 via its heparin-binding domain

(2008) Suhita Gayen Betal et al.   Translational Research