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Title
Siglec Signaling in the Tumor Microenvironment
Authors
Keywords
-
Journal
Frontiers in Immunology
Volume 12, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2021-12-13
DOI
10.3389/fimmu.2021.790317
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Note: Only part of the references are listed.- Genome-wide CRISPR screens reveal a specific ligand for the glycan-binding immune checkpoint receptor Siglec-7
- (2021) Simon Wisnovsky et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Modulation of immune cell reactivity with cis-binding Siglec agonists
- (2021) Corleone S. Delaveris et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Sialic acid-binding immunoglobulin-like lectin-15 expression on peritumoral macrophages is a favorable prognostic factor for primary central nervous system lymphoma patients
- (2021) Hirotaka Fudaba et al. Scientific Reports
- Immunopositivity for Siglec-15 in gastric cancer and its association with clinical and pathological parameters
- (2021) Michael Williams Leal Quirino et al. EUROPEAN JOURNAL OF HISTOCHEMISTRY
- First Evidence for a Role of Siglec-8 in Breast Cancer
- (2021) Anna Trebo et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Genetic glycoengineering in mammalian cells
- (2021) Yoshiki Narimatsu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Identification and functional characterization of a Siglec-7 counter-receptor on K562 cells
- (2021) Atsushi Yoshimura et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A CD22–Shp1 phosphatase axis controls integrin β7 display and B cell function in mucosal immunity
- (2021) Romain Ballet et al. NATURE IMMUNOLOGY
- Sialic acids in pancreatic cancer cells drive tumour-associated macrophage differentiation via the Siglec receptors Siglec-7 and Siglec-9
- (2021) Ernesto Rodriguez et al. Nature Communications
- Sialic acid‐binding immunoglobulin‐like lectin (Siglec)‐15 is a rapidly internalised cell‐surface antigen expressed by acute myeloid leukaemia cells
- (2021) Huan Cao et al. BRITISH JOURNAL OF HAEMATOLOGY
- Small RNAs are modified with N-glycans and displayed on the surface of living cells
- (2021) Ryan A. Flynn et al. CELL
- Nanoparticles Displaying Allergen and Siglec-8 Ligands Suppress IgE-FcεRI–Mediated Anaphylaxis and Desensitize Mast Cells to Subsequent Antigen Challenge
- (2021) Shiteng Duan et al. JOURNAL OF IMMUNOLOGY
- Probing the binding specificities of human Siglecs by cell-based glycan arrays
- (2021) Christian Büll et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Siglec-6 is a novel target for CAR T-cell therapy in acute myeloid leukemia (AML)
- (2021) Hardikkumar Jetani et al. BLOOD
- Siglec and anti-Siglec therapies
- (2021) Gavuthami Murugesan et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- Sialic Acid-Siglec Axis in Human Immune Regulation, Involvement in Autoimmunity and Cancer and Potential Therapeutic Treatments
- (2021) Elena Gianchecchi et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Display of the human mucinome with defined O-glycans by gene engineered cells
- (2021) Rebecca Nason et al. Nature Communications
- Sialic Acid Ligands of CD28 Suppress Costimulation of T Cells
- (2021) Landon J. Edgar et al. ACS Central Science
- Modulation of Siglec-7 Signaling Via In Situ-Created High-Affinity cis-Ligands
- (2021) Senlian Hong et al. ACS Central Science
- Siglec Ligands
- (2021) Anabel Gonzalez-Gil et al. Cells
- Siglecs as Immune Cell Checkpoints in Disease
- (2020) Shiteng Duan et al. Annual Review of Immunology
- Siglec-10 expression is up-regulated in activated human CD4+ T cells
- (2020) E. Bandala-Sanchez et al. HUMAN IMMUNOLOGY
- Sialoglycans and Siglecs Can Shape the Tumor Immune Microenvironment
- (2020) Stephanie van de Wall et al. TRENDS IN IMMUNOLOGY
- Glycoengineering of Natural Killer Cells with CD22 Ligands for Enhanced Anticancer Immunotherapy
- (2020) Xianwu Wang et al. ACS Central Science
- Mucins and the Microbiome
- (2020) Gunnar C. Hansson Annual Review of Biochemistry
- α2,3 linkage of sialic acid to a GPI anchor and an unpredicted GPI attachment site in human prion protein
- (2020) Atsushi Kobayashi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Sialic Acid-Siglec Axis as Molecular Checkpoints Targeting of Immune System: Smart Players in Pathology and Conventional Therapy
- (2020) Przemyslaw Wielgat et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Sialylation of Human Natural Killer (NK) Cells Is Regulated by IL-2
- (2020) Philip Rosenstock et al. Journal of Clinical Medicine
- Siglec-15 as an emerging target for next-generation cancer immunotherapy
- (2020) Jingwei Sun et al. CLINICAL CANCER RESEARCH
- Global view of human protein glycosylation pathways and functions
- (2020) Katrine T. Schjoldager et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Tools to study and target the Siglec–sialic acid axis in cancer
- (2020) Heinz Läubli et al. FEBS Journal
- Behavior of glycolylated sialoglycans in the binding pockets of murine and human CD22
- (2020) Cristina Di Carluccio et al. iScience
- Activation of CD8+ T Cell Responses after Melanoma Antigen Targeting to CD169+ Antigen Presenting Cells in Mice and Humans
- (2019) Dieke van Dinther et al. Cancers
- Siglec-15 as an immune suppressor and potential target for normalization cancer immunotherapy
- (2019) Jun Wang et al. NATURE MEDICINE
- Human Tumor-Associated Macrophage and Monocyte Transcriptional Landscapes Reveal Cancer-Specific Reprogramming, Biomarkers, and Therapeutic Targets
- (2019) Luca Cassetta et al. CANCER CELL
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- (2019) Kyle J. Bednar et al. ACS Chemical Biology
- Expression profiling of immune inhibitory Siglecs and their ligands in patients with glioma
- (2019) Kim C. M. Santegoets et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- The ceramide moiety of disialoganglioside (GD3) is essential for GD3 recognition by the sialic acid-binding lectin SIGLEC7 on the cell surface
- (2019) Noboru Hashimoto et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Siglec-9 Regulates an Effector Memory CD8+ T-cell Subset That Congregates in the Melanoma Tumor Microenvironment
- (2019) Quentin Haas et al. Cancer Immunology Research
- Protein Glycosylation and Tumor Microenvironment Alterations Driving Cancer Hallmarks
- (2019) Andreia Peixoto et al. Frontiers in Oncology
- An Atlas of Human Glycosylation Pathways Enables Display of the Human Glycome by Gene Engineered Cells
- (2019) Yoshiki Narimatsu et al. MOLECULAR CELL
- CD24 signalling through macrophage Siglec-10 is a target for cancer immunotherapy
- (2019) Amira A. Barkal et al. NATURE
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- (2019) Yujuan Li et al. Cancer Management and Research
- The sialoglycan-Siglec glyco-immune checkpoint – a target for improving innate and adaptive anti-cancer immunity
- (2019) Anne Bärenwaldt et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- A Sulfonamide Sialoside Analogue for Targeting Siglec-8 and -F on Immune Cells
- (2019) Corwin M. Nycholat et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Glycan modification of glioblastoma-derived extracellular vesicles enhances receptor-mediated targeting of dendritic cells
- (2019) Sophie A. Dusoswa et al. Journal of Extracellular Vesicles
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- (2019) Rie Suematsu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2018) Esther Bandala-Sanchez et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- GM3(Neu5Gc) ganglioside: an evolution fixed neoantigen for cancer immunotherapy
- (2018) Mayrel Labrada et al. SEMINARS IN ONCOLOGY
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- (2018) Dieke van Dinther et al. Cell Reports
- Self-associated molecular patterns mediate cancer immune evasion by engaging Siglecs on T cells
- (2018) Michal A. Stanczak et al. JOURNAL OF CLINICAL INVESTIGATION
- Comparison of Protein and Peptide Targeting for the Development of a CD169-Based Vaccination Strategy Against Melanoma
- (2018) Dieke van Dinther et al. Frontiers in Immunology
- Disruption of sialic acid metabolism drives tumor growth by augmenting CD8+ T cell apoptosis
- (2018) Lenneke A.M. Cornelissen et al. INTERNATIONAL JOURNAL OF CANCER
- Sialic Acid–Dependent Inhibition of T Cells by Exosomal Ganglioside GD3 in Ovarian Tumor Microenvironments
- (2018) Gautam N. Shenoy et al. JOURNAL OF IMMUNOLOGY
- Possible Influences of Endogenous and Exogenous Ligands on the Evolution of Human Siglecs
- (2018) Takashi Angata Frontiers in Immunology
- Identification of lectin counter-receptors on cell membranes by proximity labeling
- (2017) Gang Wu et al. GLYCOBIOLOGY
- Siglec-8 and Siglec-9 binding specificities and endogenous airway ligand distributions and properties
- (2017) Huifeng Yu et al. GLYCOBIOLOGY
- Human CD22 Inhibits Murine B Cell Receptor Activation in a Human CD22 Transgenic Mouse Model
- (2017) Kyle J. Bednar et al. JOURNAL OF IMMUNOLOGY
- CD22 Ligands on a Natural N-Glycan Scaffold Efficiently Deliver Toxins to B-Lymphoma Cells
- (2017) Wenjie Peng et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Secreted Ectodomain of SIGLEC-9 and MCP-1 Synergistically Improve Acute Liver Failure in Rats by Altering Macrophage Polarity
- (2017) Takanori Ito et al. Scientific Reports
- Protein Sialylation Regulates a Gene Expression Signature that Promotes Breast Cancer Cell Pathogenicity
- (2016) Rebecca A. Kohnz et al. ACS Chemical Biology
- The CD169 sialoadhesin molecule mediates cytotoxic T-cell responses to tumour apoptotic vesicles
- (2016) Lane VC Black et al. IMMUNOLOGY AND CELL BIOLOGY
- CD169 identifies an anti-tumour macrophage subpopulation in human hepatocellular carcinoma
- (2016) Yi Zhang et al. JOURNAL OF PATHOLOGY
- The mucin MUC1 modulates the tumor immunological microenvironment through engagement of the lectin Siglec-9
- (2016) Richard Beatson et al. NATURE IMMUNOLOGY
- Structural basis for sulfation-dependent self-glycan recognition by the human immune-inhibitory receptor Siglec-8
- (2016) Johannes M. Pröpster et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- SCS macrophages suppress melanoma by restricting tumor-derived vesicle-B cell interactions
- (2016) F. Pucci et al. SCIENCE
- Sialic Acid Mimetics to Target the Sialic Acid–Siglec Axis
- (2016) Christian Büll et al. TRENDS IN BIOCHEMICAL SCIENCES
- Besides an ITIM/SHP-1-dependent pathway, CD22 collaborates with Grb2 and plasma membrane calcium-ATPase in an ITIM/SHP-1-independent pathway of attenuation of Ca2+i signal in B cells
- (2016) Jie Chen et al. Oncotarget
- Tumor sialylation impedes T cell mediated anti-tumor responses while promoting tumor associated-regulatory T cells
- (2016) Maurizio Perdicchio et al. Oncotarget
- Protein Glycosylation in Cancer
- (2015) Sean R. Stowell et al. Annual Review of Pathology-Mechanisms of Disease
- Pathobiological implications of mucin glycans in cancer: Sweet poison and novel targets
- (2015) Seema Chugh et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
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- (2015) F. Gasparrini et al. EMBO JOURNAL
- Antigen targeting reveals splenic CD169+macrophages as promoters of germinal center B-cell responses
- (2015) Henrike Veninga et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Sialic acids in cancer biology and immunity
- (2015) Oliver M T Pearce et al. GLYCOBIOLOGY
- Unmasking of CD22 Co-receptor on Germinal Center B-cells Occurs by Alternative Mechanisms in Mouse and Man
- (2015) Matthew S. Macauley et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Siglec-10 is associated with survival and natural killer cell dysfunction in hepatocellular carcinoma
- (2015) Pei Zhang et al. JOURNAL OF SURGICAL RESEARCH
- Transforming growth factor beta 1 up-regulates CD169 (sialoadhesin) expression on monocyte-derived dendritic cells
- (2014) Amélie De Saint Jean et al. AIDS
- Sweet escape: Sialic acids in tumor immune evasion
- (2014) Christian Büll et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Biochemical Signaling of PD-1 on T Cells and Its Functional Implications
- (2014) Vassiliki A. Boussiotis et al. CANCER JOURNAL
- Sialic Acids Sweeten a Tumor's Life
- (2014) C. Bull et al. CANCER RESEARCH
- Cancer intelligence acquired (CIA): tumor glycosylation and sialylation codes dismantling antitumor defense
- (2014) Kayluz Frias Boligan et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Lectin Galactoside-binding Soluble 3 Binding Protein (LGALS3BP) Is a Tumor-associated Immunomodulatory Ligand for CD33-related Siglecs
- (2014) Heinz Läubli et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Interactions between Siglec-7/9 receptors and ligands influence NK cell–dependent tumor immunosurveillance
- (2014) Camilla Jandus et al. JOURNAL OF CLINICAL INVESTIGATION
- Siglecs Induce Tolerance to Cell Surface Antigens by BIM-Dependent Deletion of the Antigen-Reactive B Cells
- (2014) Matthew S. Macauley et al. JOURNAL OF IMMUNOLOGY
- Engagement of myelomonocytic Siglecs by tumor-associated ligands modulates the innate immune response to cancer
- (2014) Heinz Läubli et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Siglec-E is a negative regulator of acute pulmonary neutrophil inflammation and suppresses CD11b 2-integrin-dependent signaling
- (2013) S. J. McMillan et al. BLOOD
- Rapid evolution of binding specificities and expression patterns of inhibitory CD33-related Siglecs in primates
- (2013) Vered Padler-Karavani et al. FASEB JOURNAL
- Binding of the Sialic Acid-binding Lectin, Siglec-9, to the Membrane Mucin, MUC1, Induces Recruitment of β-Catenin and Subsequent Cell Growth
- (2013) Shuhei Tanida et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cancer-Associated CD43 Glycoforms as Target of Immunotherapy
- (2013) F. M. Tuccillo et al. MOLECULAR CANCER THERAPEUTICS
- Glycocalyx engineering reveals a Siglec-based mechanism for NK cell immunoevasion
- (2013) Jason E Hudak et al. Nature Chemical Biology
- T cell regulation mediated by interaction of soluble CD52 with the inhibitory receptor Siglec-10
- (2013) Esther Bandala-Sanchez et al. NATURE IMMUNOLOGY
- CD22 ligand-binding and signaling domains reciprocally regulate B-cell Ca2+ signaling
- (2013) J. Muller et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Phenotypic change of macrophages in the progression of diabetic nephropathy; sialoadhesin-positive activated macrophages are increased in diabetic kidney
- (2012) Ryo Nagase et al. Clinical and Experimental Nephrology
- The interaction between Siglec-15 and tumor-associated sialyl-Tn antigen enhances TGF- secretion from monocytes/macrophages through the DAP12-Syk pathway
- (2012) R. Takamiya et al. GLYCOBIOLOGY
- Programmed cell death 1 forms negative costimulatory microclusters that directly inhibit T cell receptor signaling by recruiting phosphatase SHP2
- (2012) Tadashi Yokosuka et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Biomarkers of eosinophil involvement in allergic and eosinophilic diseases: Review of phenotypic and serum markers including a novel assay to quantify levels of soluble Siglec-8
- (2012) Ho Jeong Na et al. JOURNAL OF IMMUNOLOGICAL METHODS
- Colonic Epithelial Cells Express Specific Ligands for Mucosal Macrophage Immunosuppressive Receptors Siglec-7 and -9
- (2012) K. Miyazaki et al. JOURNAL OF IMMUNOLOGY
- Engagement of Siglec-7 Receptor Induces a Pro-Inflammatory Response Selectively in Monocytes
- (2012) Stefania Varchetta et al. PLoS One
- Expression of Siglec-11 by human and chimpanzee ovarian stromal cells, with uniquely human ligands: implications for human ovarian physiology and pathology
- (2011) X. Wang et al. GLYCOBIOLOGY
- Epitope mapping, expression and post-translational modifications of two isoforms of CD33 (CD33M and CD33m) on lymphoid and myeloid human cells
- (2011) A. B. Perez-Oliva et al. GLYCOBIOLOGY
- Flow cytometric study of potential target antigens (CD19, CD20, CD22, CD33) for antibody-based immunotherapy in acute lymphoblastic leukemia: analysis of 552 cases
- (2011) Sara Raponi et al. LEUKEMIA & LYMPHOMA
- Epigenetic Silencing of the Sulfate Transporter Gene DTDST Induces Sialyl Lewisx Expression and Accelerates Proliferation of Colon Cancer Cells
- (2010) A. Yusa et al. CANCER RESEARCH
- Ganglioside DSGb5, preferred ligand for Siglec-7, inhibits NK cell cytotoxicity against renal cell carcinoma cells
- (2010) Y. Kawasaki et al. GLYCOBIOLOGY
- CD169-Positive Macrophages Dominate Antitumor Immunity by Crosspresenting Dead Cell-Associated Antigens
- (2010) Kenichi Asano et al. IMMUNITY
- Surface antigens analysis reveals significant expression of candidate targets for immunotherapy in adult acute lymphoid leukemia
- (2010) Pier Paolo Piccaluga et al. LEUKEMIA & LYMPHOMA
- Human Siglec-10 can bind to vascular adhesion protein-1 and serves as its substrate
- (2009) E. Kivi et al. BLOOD
- Gangliosides in cell recognition and membrane protein regulation
- (2009) Pablo HH Lopez et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- Analysis of sialoadhesin expression on mouse alveolar macrophages
- (2009) Julie Ducreux et al. IMMUNOLOGY LETTERS
- CD24 and Siglec-10 Selectively Repress Tissue Damage-Induced Immune Responses
- (2009) G.-Y. Chen et al. SCIENCE
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- (2008) Margot G. Paulick et al. BIOCHEMISTRY
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- (2008) Ri-Yao Yang et al. EXPERT REVIEWS IN MOLECULAR MEDICINE
- Sialoadhesin Expressed on IFN-Induced Monocytes Binds HIV-1 and Enhances Infectivity
- (2008) Hans Rempel et al. PLoS One
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