The mucin MUC1 modulates the tumor immunological microenvironment through engagement of the lectin Siglec-9

MYC regulates the antitumor immune response through CD47 and PD-L1

(2016) S. C. Casey et al.   SCIENCE

Environmental immune disruptors, inflammation and cancer risk

(2015) Patricia A. Thompson et al.   CARCINOGENESIS

The functional contribution of calcium ion flux heterogeneity in T cells

(2015) Susan N Christo et al.   IMMUNOLOGY AND CELL BIOLOGY

Pembrolizumab for the Treatment of Non–Small-Cell Lung Cancer

(2015) Edward B. Garon et al.   NEW ENGLAND JOURNAL OF MEDICINE

Silencing of plasminogen activator inhibitor-1 suppresses colorectal cancer progression and liver metastasis

(2015) Han Chen et al.   SURGERY

Nitric oxide synthase in innate and adaptive immunity: an update

(2015) Christian Bogdan   TRENDS IN IMMUNOLOGY

The Breast Cancer-Associated Glycoforms of MUC1, MUC1-Tn and sialyl-Tn, Are Expressed in COSMC Wild-Type Cells and Bind the C-Type Lectin MGL

(2015) Richard Beatson et al.   PLoS One

Plasminogen activator inhibitor-1 regulates infiltration of macrophages into melanoma via phosphorylation of FAK-Tyr925

(2014) Bikash Thapa et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines

(2014) Peter J. Murray et al.   IMMUNITY

Tumor-Associated Macrophages: From Mechanisms to Therapy

(2014) Roy Noy et al.   IMMUNITY

Nuclear Factor κB–Dependent Regulation of Angiogenesis, and Metastasis in an In Vivo Model of Thyroid Cancer Is Associated With Secreted Interleukin-8

(2014) Kevin T. Bauerle et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Interactions between Siglec-7/9 receptors and ligands influence NK cell–dependent tumor immunosurveillance

(2014) Camilla Jandus et al.   JOURNAL OF CLINICAL INVESTIGATION

Tumor-Associated Macrophages are Correlated with Tamoxifen Resistance in the Postmenopausal Breast Cancer Patients

(2014) Qi-jia Xuan et al.   PATHOLOGY & ONCOLOGY RESEARCH

Engagement of myelomonocytic Siglecs by tumor-associated ligands modulates the innate immune response to cancer

(2014) Heinz Läubli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recent insights into the role of the PD-1/PD-L1 pathway in immunological tolerance and autoimmunity

(2013) Elena Gianchecchi et al.   AUTOIMMUNITY REVIEWS

Binding of the Sialic Acid-binding Lectin, Siglec-9, to the Membrane Mucin, MUC1, Induces Recruitment of β-Catenin and Subsequent Cell Growth

(2013) Shuhei Tanida et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glycocalyx engineering reveals a Siglec-based mechanism for NK cell immunoevasion

(2013) Jason E Hudak et al.   Nature Chemical Biology

Microenvironmental regulation of tumor progression and metastasis

(2013) Daniela F Quail et al.   NATURE MEDICINE

Cyclooxygenase-2 Enzyme Induces the Expression of the α-2,3-Sialyltransferase-3 (ST3Gal-I) in Breast Cancer

(2012) Daisy Sproviero et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tumor-mediated inhibition of human dendritic cell differentiation and function is consistently counteracted by combined p38 MAPK and STAT3 inhibition

(2012) Dinja Oosterhoff et al.   OncoImmunology

Immunology in the clinic review series; focus on cancer: tumour-associated macrophages: undisputed stars of the inflammatory tumour microenvironment

(2011) P. Allavena et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis

(2011) Bin-Zhi Qian et al.   NATURE

Immunomodulation of monocyte-derived dendritic cells through ligation of tumor-produced mucins to Siglec-9

(2010) Mariko Ohta et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Macrophage Diversity Enhances Tumor Progression and Metastasis

(2010) Bin-Zhi Qian et al.   CELL

Over-expression of ST3Gal-I promotes mammary tumorigenesis

(2010) Gianfranco Picco et al.   GLYCOBIOLOGY

Identification of Siglec-9 as the receptor for MUC16 on human NK cells, B cells, and monocytes

(2010) Jennifer A. Belisle et al.   Molecular Cancer

Molecular mimicry of host sialylated glycans allows a bacterial pathogen to engage neutrophil Siglec-9 and dampen the innate immune response

(2009) A. F. Carlin et al.   BLOOD