Siglec-8 and Siglec-9 binding specificities and endogenous airway ligand distributions and properties

Regulation of airway inflammation by Siglec-8 and Siglec-9 sialoglycan ligand expression

(2016) Robert P. Schleimer et al.   Current Opinion in Allergy and Clinical Immunology

“Siglec”ting the allergic response for therapeutic targeting

(2016) Bruce S Bochner   GLYCOBIOLOGY

Studies on the Detection, Expression, Glycosylation, Dimerization, and Ligand Binding Properties of Mouse Siglec-E

(2016) Shoib Siddiqui et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glycobiology simplified: diverse roles of glycan recognition in inflammation

(2016) Ronald L. Schnaar   JOURNAL OF LEUKOCYTE BIOLOGY

Structural basis for sulfation-dependent self-glycan recognition by the human immune-inhibitory receptor Siglec-8

(2016) Johannes M. Pröpster et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sialic Acid Mimetics to Target the Sialic Acid–Siglec Axis

(2016) Christian Büll et al.   TRENDS IN BIOCHEMICAL SCIENCES

Efficient Mapping of Sulfated Glycotopes by Negative Ion Mode nanoLC–MS/MS-Based Sulfoglycomic Analysis of Permethylated Glycans

(2015) Chu-Wen Cheng et al.   ANALYTICAL CHEMISTRY

Endogenous airway mucins carry glycans that bind Siglec-F and induce eosinophil apoptosis

(2015) Takumi Kiwamoto et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Expression of ligands for Siglec-8 and Siglec-9 in human airways and airway cells

(2015) Yi Jia et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Host and pathogen hyaluronan signal through human siglec-9 to suppress neutrophil activation

(2015) Ismael Secundino et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Neutrophils in asthma—A review

(2015) Olga Ciepiela et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Therapeutic Targeting of Siglecs using Antibody- and Glycan-Based Approaches

(2015) Takashi Angata et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Siglec receptors impact mammalian lifespan by modulating oxidative stress

(2015) Flavio Schwarz et al.   eLife

Asthma and chronic obstructive pulmonary disease overlap: asthmatic chronic obstructive pulmonary disease or chronic obstructive asthma?

(2015) Annelies Slats et al.   Therapeutic Advances in Respiratory Disease

Role of alveolar macrophages in chronic obstructive pulmonary disease

(2014) Ross Vlahos   Frontiers in Immunology

Siglec-E is a negative regulator of acute pulmonary neutrophil inflammation and suppresses CD11b  2-integrin-dependent signaling

(2013) S. J. McMillan et al.   BLOOD

Asthma and Chronic Obstructive Pulmonary Disease

(2013) Dirkje S. Postma et al.   CLINICS IN CHEST MEDICINE

Neutrophils and emerging targets for treatment in chronic obstructive pulmonary disease

(2013) Mariska Meijer et al.   Expert Review of Clinical Immunology

Rapid evolution of binding specificities and expression patterns of inhibitory CD33-related Siglecs in primates

(2013) Vered Padler-Karavani et al.   FASEB JOURNAL

Mice deficient in the St3gal3 gene product α2,3 sialyltransferase (ST3Gal-III) exhibit enhanced allergic eosinophilic airway inflammation

(2013) Takumi Kiwamoto et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Galactose 6-O-Sulfotransferases Are Not Required for the Generation of Siglec-F Ligands in Leukocytes or Lung Tissue

(2013) Michael L. Patnode et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Siglecs as sensors of self in innate and adaptive immune responses

(2012) James C. Paulson et al.   Annals of the New York Academy of Sciences

Global metabolic inhibitors of sialyl- and fucosyltransferases remodel the glycome

(2012) Cory D Rillahan et al.   Nature Chemical Biology

Analysis of mucosal mucins separated by SDS-urea agarose polyacrylamide composite gel electrophoresis

(2011) Samah M. A. Issa et al.   ELECTROPHORESIS

Early Murine T-lymphocyte Activation Is Accompanied by a Switch fromN-Glycolyl- toN-Acetyl-neuraminic Acid and Generation of Ligands for Siglec-E

(2011) Pierre Redelinghuys et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Polymorphisms in the sialic acid-binding immunoglobulin-like lectin-8 (Siglec-8) gene are associated with susceptibility to asthma

(2010) Pei-Song Gao et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Sialidase enhances recovery from spinal cord contusion injury

(2010) A. Mountney et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Eosinophil-Selective Binding and Proapoptotic Effect in Vitro of a Synthetic Siglec-8 Ligand, Polymeric 6'-Sulfated Sialyl Lewis X

(2009) S. A. Hudson et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Interleukin-5 Priming of Human Eosinophils Alters Siglec-8–Mediated Apoptosis Pathways

(2007) Esra Nutku-Bilir et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY