In Silico Modeling of the Influence of Environment on Amyloid Folding Using FOD-M Model

AA amyloid fibrils from diseased tissue are structurally different from in vitro formed SAA fibrils

(2021) Akanksha Bansal et al.   Nature Communications

Divergence Entropy-Based Evaluation of Hydrophobic Core in Aggressive and Resistant Forms of Transthyretin

(2021) Mateusz Banach et al.   Entropy

Model of Environmental Membrane Field for Transmembrane Proteins

(2021) Irena Roterman et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Solubility and Aggregation of Selected Proteins Interpreted on the Basis of Hydrophobicity Distribution

(2021) Magdalena Ptak-Kaczor et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Functional Significance of Hydrophobic Residue Distribution in Bacterial Beta-Barrel Transmembrane Proteins

(2021) Irena Roterman et al.   Membranes

Intrinsically disordered proteins in biology: one for all, all for one

(2020) Inmaculada Yruela et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Water as a Good Solvent for Unfolded Proteins: Folding and Collapse are Fundamentally Different

(2020) Patricia L. Clark et al.   JOURNAL OF MOLECULAR BIOLOGY

Intrinsic Disorder-Based Design of Stable Globular Proteins

(2020) Galina S. Nagibina et al.   Biomolecules

Cryo-EM structure of a human prion fibril with a hydrophobic, protease-resistant core

(2020) Calina Glynn et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Cryo-EM structure of a neuronal functional amyloid implicated in memory persistence in Drosophila

(2020) Ruben Hervas et al.   SCIENCE

Role of aromatic amino acids in amyloid self-assembly

(2020) Ivana M. Stanković et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Cryo-EM structure of an amyloid fibril formed by full-length human prion protein

(2020) Li-Qiang Wang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Downhill, Ultrafast and Fast Folding Proteins Revised

(2020) Mateusz Banach et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A β-barrel for oil transport through lipid membranes: Dynamic NMR structures of AlkL

(2020) Tobias Schubeis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cryo-EM structure of cardiac amyloid fibrils from an immunoglobulin light chain AL amyloidosis patient

(2019) Paolo Swuec et al.   Nature Communications

Impact of Amyloid Polymorphism on Prion-Chaperone Interactions in Yeast

(2019) Andrea N. Killian et al.   Viruses-Basel

Functional Amyloids

(2019) Daniel Otzen et al.   Cold Spring Harbor Perspectives in Biology

Cryo-EM structures of four polymorphic TDP-43 amyloid cores

(2019) Qin Cao et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Intrinsically Disordered Proteins in Chronic Diseases

(2019) Kulkarni et al.   Biomolecules

Adsorption of Phospholipids at the Air-Water Surface

(2019) Xuan Bai et al.   BIOPHYSICAL JOURNAL

Emerging links between cerebrovascular and neurodegenerative diseases—a special role for pericytes

(2019) Urban Lendahl et al.   EMBO REPORTS

DisProt: intrinsic protein disorder annotation in 2020

(2019) András Hatos et al.   NUCLEIC ACIDS RESEARCH

Cryo-EM structure of a transthyretin-derived amyloid fibril from a patient with hereditary ATTR amyloidosis

(2019) Matthias Schmidt et al.   Nature Communications

The Amyloid as a Ribbon-Like Micelle in Contrast to Spherical Micelles Represented by Globular Proteins

(2019) Mateusz Banach et al.   MOLECULES

Structural evidence for the critical role of the prion protein hydrophobic region in forming an infectious prion

(2019) Romany Abskharon et al.   PLoS Pathogens

Amyloid Polymorphism in the Protein Folding and Aggregation Energy Landscape

(2018) Jozef Adamcik et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Amyloid assembly and disassembly

(2018) Edward Chuang et al.   JOURNAL OF CELL SCIENCE

Analysis of Global and Site-Specific Radiation Damage in Cryo-EM

(2018) Johan Hattne et al.   STRUCTURE

Immunoglobulin light chain amyloid aggregation

(2018) Luis M. Blancas-Mejia et al.   CHEMICAL COMMUNICATIONS

Cryo-EM of full-length α-synuclein reveals fibril polymorphs with a common structural kernel

(2018) Binsen Li et al.   Nature Communications

Structural basis for the complete resistance of the human prion protein mutant G127V to prion disease

(2018) Zhen Zheng et al.   Scientific Reports

Dimerization of Tyr136Cys alpha-synuclein prevents amyloid transformation of wild type alpha-synuclein

(2017) K.V. Barinova et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Cryo-EM structures of tau filaments from Alzheimer’s disease

(2017) Anthony W. P. Fitzpatrick et al.   NATURE

Innovative scattering analysis shows that hydrophobic disordered proteins are expanded in water

(2017) Joshua A. Riback et al.   SCIENCE

When fast is better: protein folding fundamentals and mechanisms from ultrafast approaches

(2016) V. Munoz et al.   BIOCHEMICAL JOURNAL

Limited cooperativity in protein folding

(2016) Victor Muñoz et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Role of Disulfide Bonds in Stabilizing the Conformation of Selected Enzymes—An Approach Based on Divergence Entropy Applied to the Structure of Hydrophobic Core in Proteins

(2016) Mateusz Banach et al.   Entropy

Influence of the Aqueous Environment on Protein Structure—A Plausible Hypothesis Concerning the Mechanism of Amyloidogenesis

(2016) Irena Roterman et al.   Entropy

Atomic Resolution Structure of Monomorphic Aβ42 Amyloid Fibrils

(2016) Michael T. Colvin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Neurodegenerative diseases

(2016) Marie-Thérèse Heemels   NATURE

The activities of amyloids from a structural perspective

(2016) Roland Riek et al.   NATURE

Solid-state NMR structure of a pathogenic fibril of full-length human α-synuclein

(2016) Marcus D Tuttle et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Ab initio structure determination from prion nanocrystals at atomic resolution by MicroED

(2016) Michael R. Sawaya et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Solid-state NMR structure of a pathogenic fibril of full-length human α-synuclein

(2016) Marcus D Tuttle et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Crystal Structures of Polymorphic Prion Protein β1 Peptides Reveal Variable Steric Zipper Conformations

(2015) Lu Yu et al.   BIOCHEMISTRY

Application of Divergence Entropy to Characterize the Structure of the Hydrophobic Core in DNA Interacting Proteins

(2015) Barbara Kalinowska et al.   Entropy

Aβ(1–42) fibril structure illuminates self-recognition and replication of amyloid in Alzheimer's disease

(2015) Yiling Xiao et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structure-based drug design identifies polythiophenes as antiprion compounds

(2015) Uli S. Herrmann et al.   Science Translational Medicine

Modeling an In-Register, Parallel “Iowa” Aβ Fibril Structure Using Solid-State NMR Data from Labeled Samples with Rosetta

(2015) Nikolaos G. Sgourakis et al.   STRUCTURE

Aβ(1–42) fibril structure illuminates self-recognition and replication of amyloid in Alzheimer's disease

(2015) Yiling Xiao et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Atomic-Resolution Three-Dimensional Structure of Amyloid β Fibrils Bearing the Osaka Mutation

(2014) Anne K. Schütz et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Classification of Intrinsically Disordered Regions and Proteins

(2014) Robin van der Lee et al.   CHEMICAL REVIEWS

The physical chemistry of the amyloid phenomenon: thermodynamics and kinetics of filamentous protein aggregation

(2014) Alexander K. Buell et al.   Essays in Biochemistry

The fuzzy oil drop model, based on hydrophobicity density distribution, generalizes the influence of water environment on protein structure and function

(2014) Mateusz Banach et al.   JOURNAL OF THEORETICAL BIOLOGY

Shaking Alone Induces De Novo Conversion of Recombinant Prion Proteins to β-Sheet Rich Oligomers and Fibrils

(2014) Carol L. Ladner-Keay et al.   PLoS One

Insulin, IGF-1 and GLP-1 signaling in neurodegenerative disorders: Targets for disease modification?

(2014) Fares Bassil et al.   PROGRESS IN NEUROBIOLOGY

Crystal Structure of a Human Prion Protein Fragment Reveals a Motif for Oligomer Formation

(2013) Marcin I. Apostol et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Neurodegenerative diseases: challenges and opportunities

(2012) Gregory D Cuny   Future Medicinal Chemistry

The Amyloid-Congo Red Interface at Atomic Resolution

(2011) Anne K. Schütz et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Amyloid Structure: Conformational Diversity and Consequences

(2011) Brandon H. Toyama et al.   Annual Review of Biochemistry

Monolayers at air-water interfaces: from origins-of-life to nanotechnology

(2011) Katsuhiko Ariga et al.   CHEMICAL RECORD

The Acidic Transcription Activator Gcn4 Binds the Mediator Subunit Gal11/Med15 Using a Simple Protein Interface Forming a Fuzzy Complex

(2011) Peter S. Brzovic et al.   MOLECULAR CELL

Conformational Conversion during Amyloid Formation at Atomic Resolution

(2011) Timo Eichner et al.   MOLECULAR CELL

Solution structure of Rap1 BRCT domain from Saccharomyces cerevisiae reveals a novel fold

(2010) Wen Zhang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Neurodegenerative Diseases: A Growing Challenge

(2010) S L Miksys et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Crystallographic Studies of Prion Protein (PrP) Segments Suggest How Structural Changes Encoded by Polymorphism at Residue 129 Modulate Susceptibility to Human Prion Disease

(2010) Marcin I. Apostol et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Aminopyrazine Inhibitors Binding to an Unusual Inactive Conformation of the Mitotic Kinase Nek2: SAR and Structural Characterization

(2010) Daniel K. Whelligan et al.   JOURNAL OF MEDICINAL CHEMISTRY

Atomic-Resolution Three-Dimensional Structure of HET-s(218−289) Amyloid Fibrils by Solid-State NMR Spectroscopy

(2010) Hélène Van Melckebeke et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Conformational diversity in prion protein variants influences intermolecular β-sheet formation

(2009) Seungjoo Lee et al.   EMBO JOURNAL

On the Structure of Water at the Aqueous/Air Interface

(2009) Yubo Fan et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Intrinsically Disordered Proteins in Human Diseases: Introducing the D2 Concept

(2008) Vladimir N. Uversky et al.   Annual Review of Biophysics

Possible role of region 152-156 in the structural duality of a peptide fragment from sheep prion protein

(2004) Simon Megy et al.   PROTEIN SCIENCE