The physical chemistry of the amyloid phenomenon: thermodynamics and kinetics of filamentous protein aggregation

The Role of Stable α-Synuclein Oligomers in the Molecular Events Underlying Amyloid Formation

(2014) Nikolai Lorenzen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Presence of an Air–Water Interface Affects Formation and Elongation of α-Synuclein Fibrils

(2014) Silvia Campioni et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nucleation-conversion-polymerization reactions of biological macromolecules with prenucleation clusters

(2014) Gonzalo A. Garcia et al.   PHYSICAL REVIEW E

Spatial Propagation of Protein Polymerization

(2014) S. I. A. Cohen et al.   PHYSICAL REVIEW LETTERS

Solution conditions determine the relative importance of nucleation and growth processes in  -synuclein aggregation

(2014) A. K. Buell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The BRICHOS Domain, Amyloid Fibril Formation, and Their Relationship

(2013) Stefan D. Knight et al.   BIOCHEMISTRY

An Imaging and Systems Modeling Approach to Fibril Breakage Enables Prediction of Amyloid Behavior

(2013) Wei-Feng Xue et al.   BIOPHYSICAL JOURNAL

Electrostatic Effects in Filamentous Protein Aggregation

(2013) Alexander K. Buell et al.   BIOPHYSICAL JOURNAL

Nanobodies Raised against Monomeric α-Synuclein Distinguish between Fibrils at Different Maturation Stages

(2013) Tim Guilliams et al.   JOURNAL OF MOLECULAR BIOLOGY

Polymorph-Specific Kinetics and Thermodynamics of β-Amyloid Fibril Growth

(2013) Wei Qiang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Direct Observation of Heterogeneous Amyloid Fibril Growth Kinetics via Two-Color Super-Resolution Microscopy

(2013) Dorothea Pinotsi et al.   NANO LETTERS

Influence of specific HSP70 domains on fibril formation of the yeast prion protein Ure2

(2013) L.-Q. Xu et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Macromolecular Crowding as a Suppressor of Human IAPP Fibril Formation and Cytotoxicity

(2013) Janine Seeliger et al.   PLoS One

Atomic structure and hierarchical assembly of a cross-  amyloid fibril

(2013) A. W. P. Fitzpatrick et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proliferation of amyloid- 42 aggregates occurs through a secondary nucleation mechanism

(2013) S. I. A. Cohen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Detailed Analysis of the Energy Barriers for Amyloid Fibril Growth

(2012) Alexander K. Buell et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ionic Strength Effects on Amyloid Formation by Amylin Are a Complicated Interplay among Debye Screening, Ion Selectivity, and Hofmeister Effects

(2012) Peter J. Marek et al.   BIOCHEMISTRY

Role of Elongation and Secondary Pathways in S6 Amyloid Fibril Growth

(2012) Nikolai Lorenzen et al.   BIOPHYSICAL JOURNAL

Direct Observation of the Interconversion of Normal and Toxic Forms of α-Synuclein

(2012) Nunilo Cremades et al.   CELL

Twisting Transition between Crystalline and Fibrillar Phases of Aggregated Peptides

(2012) Tuomas P. J. Knowles et al.   PHYSICAL REVIEW LETTERS

Failure of Aβ(1-40) amyloid fibrils under tensile loading

(2011) Raffaella Paparcone et al.   BIOMATERIALS

Perturbation of the Stability of Amyloid Fibrils through Alteration of Electrostatic Interactions

(2011) Sarah L. Shammas et al.   BIOPHYSICAL JOURNAL

Binding of the Molecular Chaperone αB-Crystallin to Aβ Amyloid Fibrils Inhibits Fibril Elongation

(2011) Sarah L. Shammas et al.   BIOPHYSICAL JOURNAL

Relationship between Prion Propensity and the Rates of Individual Molecular Steps of Fibril Assembly

(2011) Yi-Qian Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nucleated polymerization with secondary pathways. I. Time evolution of the principal moments

(2011) Samuel I. A. Cohen et al.   JOURNAL OF CHEMICAL PHYSICS

Metastability of Native Proteins and the Phenomenon of Amyloid Formation

(2011) Andrew J. Baldwin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The extracellular chaperone clusterin sequesters oligomeric forms of the amyloid-β1−40 peptide

(2011) Priyanka Narayan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Probing small molecule binding to amyloid fibrils

(2011) Alexander K. Buell et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Spatial Extent of Charge Repulsion Regulates Assembly Pathways for Lysozyme Amyloid Fibrils

(2011) Shannon E. Hill et al.   PLoS One

Observation of spatial propagation of amyloid assembly from single nuclei

(2011) T. P. J. Knowles et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Low-resolution structure of a vesicle disrupting  -synuclein oligomer that accumulates during fibrillation

(2011) L. Giehm et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A thermodynamic analysis of fibrillar polymorphism

(2010) Martin D. Jeppesen et al.   BIOPHYSICAL CHEMISTRY

Characterizing the Assembly of the Sup35 Yeast Prion Fragment, GNNQQNY: Structural Changes Accompany a Fiber-to-Crystal Switch

(2010) Karen E. Marshall et al.   BIOPHYSICAL JOURNAL

Nucleation of amyloid fibrils

(2010) Dimo Kashchiev et al.   JOURNAL OF CHEMICAL PHYSICS

The Thermodynamic Stability of Amyloid Fibrils Studied by Differential Scanning Calorimetry

(2010) Bertrand Morel et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Surface Attachment of Protein Fibrils via Covalent Modification Strategies

(2010) Alexander K. Buell et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Protein Aggregation in Crowded Environments

(2010) Duncan A. White et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stop-and-go kinetics in amyloid fibrillation

(2010) Jesper Ferkinghoff-Borg et al.   PHYSICAL REVIEW E

Frequency Factors in a Landscape Model of Filamentous Protein Aggregation

(2010) Alexander K. Buell et al.   PHYSICAL REVIEW LETTERS

Identifying the amylome, proteins capable of forming amyloid-like fibrils

(2010) Lukasz Goldschmidt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Thioflavine T interaction with synthetic Alzheimer's disease β-amyloid peptides: Detection of amyloid aggregation in solution

(2010) Harry Levine   PROTEIN SCIENCE

Amyloid β-Protein Aggregation Produces Highly Reproducible Kinetic Data and Occurs by a Two-Phase Process

(2009) Erik Hellstrand et al.   ACS Chemical Neuroscience

The thioflavin T fluorescence assay for amyloid fibril detection can be biased by the presence of exogenous compounds

(2009) Sean A. Hudson et al.   FEBS Journal

Crowded Cell-like Environment Accelerates the Nucleation Step of Amyloidogenic Protein Misfolding

(2009) Zheng Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An Analytical Solution to the Kinetics of Breakable Filament Assembly

(2009) T. P. J. Knowles et al.   SCIENCE

Systematic analysis of nucleation-dependent polymerization reveals new insights into the mechanism of amyloid self-assembly

(2008) Wei-Feng Xue et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Direct characterization of amyloidogenic oligomers by single-molecule fluorescence

(2008) A. Orte et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA