Influence of the Aqueous Environment on Protein Structure—A Plausible Hypothesis Concerning the Mechanism of Amyloidogenesis

Technical performance of a novel, fully automated electrochemiluminescence immunoassay for the quantitation of β-amyloid (1–42) in human cerebrospinal fluid

(2016) Tobias Bittner et al.   Alzheimers & Dementia

Abolishing HIV-1 infectivity using a polypurine tract-specific G-quadruplex-forming oligonucleotide

(2016) Maike Voges et al.   BMC INFECTIOUS DISEASES

Amyloid-like Self-Assembly of a Cellular Compartment

(2016) Elvan Boke et al.   CELL

Role of Disulfide Bonds in Stabilizing the Conformation of Selected Enzymes—An Approach Based on Divergence Entropy Applied to the Structure of Hydrophobic Core in Proteins

(2016) Mateusz Banach et al.   Entropy

Early Postmenopausal Transdermal 17β-Estradiol Therapy and Amyloid-β Deposition

(2016) Kejal Kantarci et al.   JOURNAL OF ALZHEIMERS DISEASE

Immunization Against Specific Fragments of Neurotrophin p75 Receptor Protects Forebrain Cholinergic Neurons in the Olfactory Bulbectomized Mice

(2016) Natalia Bobkova et al.   JOURNAL OF ALZHEIMERS DISEASE

Changes in insulin and insulin signaling in Alzheimer’s disease: cause or consequence?

(2016) Molly Stanley et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Synaptophysin depletion and intraneuronal Aβ in organotypic hippocampal slice cultures from huAPP transgenic mice

(2016) Claire S. Harwell et al.   Molecular Neurodegeneration

Redundant Gs-coupled serotonin receptors regulate amyloid-β metabolism in vivo

(2016) Jonathan R. Fisher et al.   Molecular Neurodegeneration

Impairments of neural circuit function in Alzheimer's disease

(2016) Marc Aurel Busche et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Serum Amyloid P Component Ameliorates Neurological Damage Caused by Expressing a Lysozyme Variant in the Central Nervous System of Drosophila melanogaster

(2016) Linda Helmfors et al.   PLoS One

Atomic-resolution structure of a disease-relevant Aβ(1–42) amyloid fibril

(2016) Marielle Aulikki Wälti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multimodality Review of Amyloid-related Diseases of the Central Nervous System

(2016) Michelle M. Miller-Thomas et al.   RADIOGRAPHICS

A simple two-state protein unfolds mechanically via multiple heterogeneous pathways at single-molecule resolution

(2016) Jörg Schönfelder et al.   Nature Communications

Fenamate NSAIDs inhibit the NLRP3 inflammasome and protect against Alzheimer’s disease in rodent models

(2016) Michael J. D. Daniels et al.   Nature Communications

Amyloid Precursor-Like Protein 2 deletion-induced retinal synaptopathy related to congenital stationary night blindness: structural, functional and molecular characteristics

(2016) Virginie Dinet et al.   Molecular Brain

Flow cytometry-based characterization of underlying clonal B and plasma cells in patients with light chain amyloidosis

(2016) Katharina Lisenko et al.   Cancer Medicine

Stepping closer to treating Alzheimer’s disease patients with BACE1 inhibitor drugs

(2016) Riqiang Yan   Translational Neurodegeneration

Common molecular mechanism of amyloid pore formation by Alzheimer’s β-amyloid peptide and α-synuclein

(2016) Coralie Di Scala et al.   Scientific Reports

Amyloid β oligomers in Alzheimer’s disease pathogenesis, treatment, and diagnosis

(2015) Kirsten L. Viola et al.   ACTA NEUROPATHOLOGICA

Evolving landscape in the management of transthyretin amyloidosis

(2015) Philip N. Hawkins et al.   ANNALS OF MEDICINE

Application of Divergence Entropy to Characterize the Structure of the Hydrophobic Core in DNA Interacting Proteins

(2015) Barbara Kalinowska et al.   Entropy

Bent out of shape: α-Synuclein misfolding and the convergence of pathogenic pathways in Parkinson's disease

(2015) Esteban Luna et al.   FEBS LETTERS

Uncovering the Mechanism of Aggregation of Human Transthyretin

(2015) Lorena Saelices et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Aβ(1–42) fibril structure illuminates self-recognition and replication of amyloid in Alzheimer's disease

(2015) Yiling Xiao et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Modeling an In-Register, Parallel “Iowa” Aβ Fibril Structure Using Solid-State NMR Data from Labeled Samples with Rosetta

(2015) Nikolaos G. Sgourakis et al.   STRUCTURE

Aβ(1–42) fibril structure illuminates self-recognition and replication of amyloid in Alzheimer's disease

(2015) Yiling Xiao et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Atomic-Resolution Three-Dimensional Structure of Amyloid β Fibrils Bearing the Osaka Mutation

(2014) Anne K. Schütz et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Hydrophobic Effect Revisited-Studies with Supramolecular Complexes Imply High-Energy Water as a Noncovalent Driving Force

(2014) Frank Biedermann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Quantification of HDL Proteins, Cardiac Events, and Mortality in Patients with Type 2 Diabetes on Hemodialysis

(2014) C. Kopecky et al.   Clinical Journal of the American Society of Nephrology

The Importance of a Gatekeeper Residue on the Aggregation of Transthyretin

(2014) Ricardo Sant'Anna et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The fuzzy oil drop model, based on hydrophobicity density distribution, generalizes the influence of water environment on protein structure and function

(2014) Mateusz Banach et al.   JOURNAL OF THEORETICAL BIOLOGY

Tensile deformation and failure of amyloid and amyloid-like protein fibrils

(2014) Max Solar et al.   NANOTECHNOLOGY

CATH: comprehensive structural and functional annotations for genome sequences

(2014) Ian Sillitoe et al.   NUCLEIC ACIDS RESEARCH

WeFold: A coopetition for protein structure prediction

(2014) George A. Khoury et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Molecular Structure of β-Amyloid Fibrils in Alzheimer’s Disease Brain Tissue

(2013) Jun-Xia Lu et al.   CELL

Hydrophobic core formation in protein complex of cathepsin

(2013) Monika Piwowar et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

PDBsum additions

(2013) Tjaart A. P. de Beer et al.   NUCLEIC ACIDS RESEARCH

Critical assessment of methods of protein structure prediction (CASP) - round x

(2013) John Moult et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

High-Speed Force Spectroscopy Unfolds Titin at the Velocity of Molecular Dynamics Simulations

(2013) F. Rico et al.   SCIENCE

Quaternary structure, aggregation and cytotoxicity of transthyretin

(2012) Mineyuki Mizuguchi et al.   AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS

Binding of Congo Red to Amyloid Protofibrils of the Alzheimer Aβ9–40 Peptide Probed by Molecular Dynamics Simulations

(2012) Chun Wu et al.   BIOPHYSICAL JOURNAL

The Amyloid State of Proteins in Human Diseases

(2012) David Eisenberg et al.   CELL

Domain swapping and amyloid fibril conformation

(2012) Patrick C.A. van der Wel   Prion

The Protein-Folding Problem, 50 Years On

(2012) K. A. Dill et al.   SCIENCE

The apicomplexan plastid and its evolution

(2011) Shigeharu Sato   CELLULAR AND MOLECULAR LIFE SCIENCES

Fuzzy oil drop model to interpret the structure of antifreeze proteins and their mutants

(2011) Mateusz Banach et al.   JOURNAL OF MOLECULAR MODELING

Structure and assembly-disassembly properties of wild-type transthyretin amyloid protofibrils observed with atomic force microscopy

(2011) Ricardo H. Pires et al.   JOURNAL OF MOLECULAR RECOGNITION

Two-intermediate model to characterize the structure of fast-folding proteins

(2011) I. Roterman et al.   JOURNAL OF THEORETICAL BIOLOGY

Effects of Congo Red on Aβ1−40 Fibril Formation Process and Morphology

(2010) Partha Pratim Bose et al.   ACS Chemical Neuroscience

Characterization of the Interaction of β-Amyloid with Transthyretin Monomers and Tetramers

(2010) Jiali Du et al.   BIOCHEMISTRY

SufD and SufC ATPase Activity Are Required for Iron Acquisition during in Vivo Fe-S Cluster Formation on SufB

(2010) Avneesh Saini et al.   BIOCHEMISTRY

Structural Basis for Acetylated Histone H4 Recognition by the Human BRD2 Bromodomain

(2010) Takashi Umehara et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Catalytic residues in hydrolases: analysis of methods designed for ligand-binding site prediction

(2010) Katarzyna Prymula et al.   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

NMR Reveals Two-Step Association of Congo Red to Amyloid β in Low-Molecular-Weight Aggregates

(2010) Marie Ø. Pedersen et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Building Fe–S proteins: bacterial strategies

(2010) Béatrice Py et al.   NATURE REVIEWS MICROBIOLOGY

Amyloidogenic Potential of Transthyretin Variants

(2009) Laura Cendron et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular Dynamism of Fe–S Cluster Biosynthesis Implicated by the Structure of the SufC2–SufD2 Complex

(2009) Kei Wada et al.   JOURNAL OF MOLECULAR BIOLOGY

Molecular and cellular aspects of protein misfolding and disease

(2008) Eszter Herczenik et al.   FASEB JOURNAL

Amyloid Fibrils of the HET-s(218-289) Prion Form a   Solenoid with a Triangular Hydrophobic Core

(2008) C. Wasmer et al.   SCIENCE