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Title
Deciphering functional tumor states at single‐cell resolution
Authors
Keywords
-
Journal
EMBO JOURNAL
Volume 41, Issue 2, Pages -
Publisher
EMBO
Online
2021-12-17
DOI
10.15252/embj.2021109221
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- (2021) Eduardo A. Torre et al. NATURE GENETICS
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- (2021) Kamen P. Simeonov et al. CANCER CELL
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- (2021) Simone Brabletz et al. EMBO JOURNAL
- Cancer evolution: Darwin and beyond
- (2021) Roberto Vendramin et al. EMBO JOURNAL
- Integrating single-cell and spatial transcriptomics to elucidate intercellular tissue dynamics
- (2021) Sophia K. Longo et al. NATURE REVIEWS GENETICS
- The Repertoire of Serous Ovarian Cancer Non-genetic Heterogeneity Revealed by Single-Cell Sequencing of Normal Fallopian Tube Epithelial Cells
- (2020) Zhiyuan Hu et al. CANCER CELL
- Cancer Genome Evolutionary Trajectories in Metastasis
- (2020) Nicolai J. Birkbak et al. CANCER CELL
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- (2020) Jin Zhao et al. CANCER LETTERS
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- (2020) Reuben Moncada et al. NATURE BIOTECHNOLOGY
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- (2020) Ryan T. Davis et al. NATURE CELL BIOLOGY
- Regenerative lineages and immune-mediated pruning in lung cancer metastasis
- (2020) Ashley M. Laughney et al. NATURE MEDICINE
- CellPhoneDB: inferring cell–cell communication from combined expression of multi-subunit ligand–receptor complexes
- (2020) Mirjana Efremova et al. Nature Protocols
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- Integrative Methods and Practical Challenges for Single-Cell Multi-omics
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- (2020) David P. Cook et al. Nature Communications
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- (2020) Nayoung Kim et al. Nature Communications
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- (2020) Allison R Pine et al. Cancer Discovery
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- (2020) Jasper Wouters et al. NATURE CELL BIOLOGY
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- (2020) Charles P. Couturier et al. Nature Communications
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- (2020) Austin E. Gillen et al. Cell Reports
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- (2020) Pauline Vieugué et al. DEVELOPMENTAL CELL
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- (2020) Yutong Sha et al. NUCLEIC ACIDS RESEARCH
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- (2013) Jeremy L. Norris et al. CHEMICAL REVIEWS
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- (2013) H. Guo et al. GENOME RESEARCH
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- In situ sequencing for RNA analysis in preserved tissue and cells
- (2013) Rongqin Ke et al. NATURE METHODS
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- (2013) M. Yu et al. SCIENCE
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- (2012) Daniel C. Koboldt et al. NATURE
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- (2012) Yuchun Luo et al. STEM CELLS
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- (2011) Benjamin Beck et al. NATURE
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- (2011) M. Schober et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2011) S. C. Bendall et al. SCIENCE
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- (2010) Salvatore Pece et al. CELL
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- (2009) Elgene Lim et al. NATURE MEDICINE
- Aldehyde Dehydrogenase as a Marker for Stem Cells
- (2008) Jan Moreb Current Stem Cell Research & Therapy
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