Identification of EMT signaling cross-talk and gene regulatory networks by single-cell RNA sequencing

Comparative Study of Transcriptomics-Based Scoring Metrics for the Epithelial-Hybrid-Mesenchymal Spectrum

(2020) Priyanka Chakraborty et al.   Frontiers in Bioengineering and Biotechnology

Decoding the mechanisms underlying cell-fate decision-making during stem cell differentiation by random circuit perturbation

(2020) Bin Huang et al.   Journal of the Royal Society Interface

Biological Networks Regulating Cell Fate Choice are Minimally Frustrated

(2020) Shubham Tripathi et al.   PHYSICAL REVIEW LETTERS

EMTome: a resource for pan-cancer analysis of epithelial-mesenchymal transition genes and signatures

(2020) Suhas V. Vasaikar et al.   BRITISH JOURNAL OF CANCER

Fat1 deletion promotes hybrid EMT state, tumour stemness and metastasis

(2020) Ievgenia Pastushenko et al.   NATURE

ZEB1 and IL-6/11-STAT3 signalling cooperate to define invasive potential of pancreatic cancer cells via differential regulation of the expression of S100 proteins

(2019) Qais Al-Ismaeel et al.   BRITISH JOURNAL OF CANCER

A pooled single-cell genetic screen identifies regulatory checkpoints in the continuum of the epithelial-to-mesenchymal transition

(2019) José L. McFaline-Figueroa et al.   NATURE GENETICS

Metabolic Regulation of Epithelial to Mesenchymal Transition: Implications for Endocrine Cancer

(2019) Debasmita Bhattacharya et al.   Frontiers in Endocrinology

Hybrid epithelial/mesenchymal phenotype(s): The ‘fittest’ for metastasis?

(2018) Mohit Kumar Jolly et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

RACIPE: a computational tool for modeling gene regulatory circuits using randomization

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An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics

(2018) Jianfang Liu et al.   CELL

S100A6 promotes the proliferation and migration of cervical cancer cells via the PI3K/Akt signaling pathway

(2018) Aifang Li et al.   Oncology Letters

The Epithelial-to-Mesenchymal Transition in Cancer

(2018) Joëlle Roche   Cancers

Identification of the tumour transition states occurring during EMT

(2018) Ievgenia Pastushenko et al.   NATURE

Hybrid epithelial/mesenchymal phenotypes promote metastasis and therapy resistance across carcinomas

(2018) Mohit Kumar Jolly et al.   PHARMACOLOGY & THERAPEUTICS

Myc mediates cancer stem-like cells and EMT changes in triple negative breast cancers cells

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Interrogating the topological robustness of gene regulatory circuits by randomization

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Snail collaborates with EGR-1 and SP-1 to directly activate transcription of MMP 9 and ZEB1

(2017) Wen-Sheng Wu et al.   Scientific Reports

Notch-Jagged signalling can give rise to clusters of cells exhibiting a hybrid epithelial/mesenchymal phenotype

(2016) Marcelo Boareto et al.   Journal of the Royal Society Interface

Early dissemination seeds metastasis in breast cancer

(2016) Hedayatollah Hosseini et al.   NATURE

Epithelial–mesenchymal transition: a new target in anticancer drug discovery

(2016) Fabrizio Marcucci et al.   NATURE REVIEWS DRUG DISCOVERY

Epithelial-to-mesenchymal transition leads to loss of EpCAM and different physical properties in circulating tumor cells from metastatic breast cancer

(2016) Kyung-A Hyun et al.   Oncotarget

DNMT1 Regulates Epithelial-Mesenchymal Transition and Cancer Stem Cells, Which Promotes Prostate Cancer Metastasis

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Recent discoveries concerning the involvement of transcription factors from the Grainyhead-like family in cancer

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Regularization Paths for Generalized Linear Models via Coordinate Descent

(2015) Jerome Friedman et al.   Journal of Statistical Software

IRF6 is the mediator of TGFβ3 during regulation of the epithelial mesenchymal transition and palatal fusion

(2015) Chen-Yeh Ke et al.   Scientific Reports

Inflammation and pancreatic cancer: molecular and functional interactions between S100A8, S100A9, NT-S100A8 and TGFβ1

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Fra-1/AP-1 induces EMT in mammary epithelial cells by modulating Zeb1/2 and TGFβ expression

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Epithelial-mesenchymal transition spectrum quantification and its efficacy in deciphering survival and drug responses of cancer patients

(2014) T. Z. Tan et al.   EMBO Molecular Medicine

Towards elucidating the connection between epithelial-mesenchymal transitions and stemness

(2014) M. K. Jolly et al.   Journal of the Royal Society Interface

Comparison of RNA-Seq and Microarray in Transcriptome Profiling of Activated T Cells

(2014) Shanrong Zhao et al.   PLoS One

ForceAtlas2, a Continuous Graph Layout Algorithm for Handy Network Visualization Designed for the Gephi Software

(2014) Mathieu Jacomy et al.   PLoS One

TGF- -induced epithelial-to-mesenchymal transition proceeds through stepwise activation of multiple feedback loops

(2014) J. Zhang et al.   Science Signaling

Sox4 Is a Master Regulator of Epithelial-Mesenchymal Transition by Controlling Ezh2 Expression and Epigenetic Reprogramming

(2013) Neha Tiwari et al.   CANCER CELL

Deadly crosstalk: Notch signaling at the intersection of EMT and cancer stem cells

(2013) Ingrid Espinoza et al.   CANCER LETTERS

Regulation of epithelial to mesenchymal transition by bone morphogenetic proteins

(2013) Natasha McCormack et al.   CELLULAR SIGNALLING

Pathway-based personalized analysis of cancer

(2013) Y. Drier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of EMT by TGFβ in cancer

(2012) Carl-Henrik Heldin et al.   FEBS LETTERS

G9a interacts with Snail and is critical for Snail-mediated E-cadherin repression in human breast cancer

(2012) Chenfang Dong et al.   JOURNAL OF CLINICAL INVESTIGATION

Lack of microRNA-101 causes E-cadherin functional deregulation through EZH2 up-regulation in intestinal gastric cancer

(2012) Joana Carvalho et al.   JOURNAL OF PATHOLOGY

E/N-cadherin switch mediates cancer progression via TGF-β-induced epithelial-to-mesenchymal transition in extrahepatic cholangiocarcinoma

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miRWalk – Database: Prediction of possible miRNA binding sites by “walking” the genes of three genomes

(2011) Harsh Dweep et al.   JOURNAL OF BIOMEDICAL INFORMATICS

Down-regulation of epithelial cadherin is required to initiate metastatic outgrowth of breast cancer

(2011) Michael K. Wendt et al.   MOLECULAR BIOLOGY OF THE CELL

TGF-β-induced epithelial to mesenchymal transition

(2009) Jian Xu et al.   CELL RESEARCH

FGFR2-related pathogenesis and FGFR2-targeted therapeutics (Review)

(2009) Katoh   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features

(2009) C. J. Creighton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epithelial-Mesenchymal Transition in Breast Cancer Relates to the Basal-like Phenotype

(2008) D. Sarrio et al.   CANCER RESEARCH

The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

(2008) Sendurai A. Mani et al.   CELL

Back and forth between cell fate specification and movement during vertebrate gastrulation

(2008) Carl-Philipp Heisenberg et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Epithelial-Mesenchymal Transition: At the Crossroads of Development and Tumor Metastasis

(2008) Jing Yang et al.   DEVELOPMENTAL CELL

The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1

(2008) Philip A. Gregory et al.   NATURE CELL BIOLOGY

A gene regulatory network orchestrates neural crest formation

(2008) Tatjana Sauka-Spengler et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY