Transcriptional diversity and bioenergetic shift in human breast cancer metastasis revealed by single-cell RNA sequencing
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Transcriptional diversity and bioenergetic shift in human breast cancer metastasis revealed by single-cell RNA sequencing
Authors
Keywords
-
Journal
NATURE CELL BIOLOGY
Volume 22, Issue 3, Pages 310-320
Publisher
Springer Science and Business Media LLC
Online
2020-03-07
DOI
10.1038/s41556-020-0477-0
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Phase I trial of IACS-010759 (IACS), a potent, selective inhibitor of complex I of the mitochondrial electron transport chain, in patients (pts) with advanced solid tumors.
- (2019) Timothy A Yap et al. JOURNAL OF CLINICAL ONCOLOGY
- Flura-seq identifies organ-specific metabolic adaptations during early metastatic colonization
- (2019) Harihar Basnet et al. eLife
- Atovaquone enhances doxorubicin’s efficacy via inhibiting mitochondrial respiration and STAT3 in aggressive thyroid cancer
- (2018) Zhuo Lv et al. JOURNAL OF BIOENERGETICS AND BIOMEMBRANES
- Integrating single-cell transcriptomic data across different conditions, technologies, and species
- (2018) Andrew Butler et al. NATURE BIOTECHNOLOGY
- Metabolic Hallmarks of Metastasis Formation
- (2018) Ilaria Elia et al. TRENDS IN CELL BIOLOGY
- Tumour heterogeneity and metastasis at single-cell resolution
- (2018) Devon A. Lawson et al. NATURE CELL BIOLOGY
- Enhancement of Aqueous Solubility and Dissolution of Celecoxib through Phosphatidylcholine-Based Dispersion Systems Solidified with Adsorbent Carriers
- (2018) Kanghee Jo et al. Pharmaceutics
- Comparative Analysis of Single-Cell RNA Sequencing Methods
- (2017) Christoph Ziegenhain et al. MOLECULAR CELL
- Decoupling genetics, lineages, and microenvironment in IDH-mutant gliomas by single-cell RNA-seq
- (2017) Andrew S. Venteicher et al. SCIENCE
- Metabolism in cancer metastasis: bioenergetics, biosynthesis, and beyond
- (2017) Shao Thing Teoh et al. Wiley Interdisciplinary Reviews-Systems Biology and Medicine
- Proline metabolism supports metastasis formation and could be inhibited to selectively target metastasizing cancer cells
- (2017) Ilaria Elia et al. Nature Communications
- Glutaminolysis drives membrane trafficking to promote invasiveness of breast cancer cells
- (2017) Emmanuel Dornier et al. Nature Communications
- mixOmics: An R package for ‘omics feature selection and multiple data integration
- (2017) Florian Rohart et al. PLoS Computational Biology
- A Biobank of Breast Cancer Explants with Preserved Intra-tumor Heterogeneity to Screen Anticancer Compounds
- (2016) Alejandra Bruna et al. CELL
- The imprinted Phlda2 gene modulates a major endocrine compartment of the placenta to regulate placental demands for maternal resources
- (2016) S.J. Tunster et al. DEVELOPMENTAL BIOLOGY
- Inhibition of fatty acid oxidation as a therapy for MYC-overexpressing triple-negative breast cancer
- (2016) Roman Camarda et al. NATURE MEDICINE
- Triple-negative breast cancer: challenges and opportunities of a heterogeneous disease
- (2016) Giampaolo Bianchini et al. Nature Reviews Clinical Oncology
- Enrichr: a comprehensive gene set enrichment analysis web server 2016 update
- (2016) Maxim V. Kuleshov et al. NUCLEIC ACIDS RESEARCH
- Expansion of the Gene Ontology knowledgebase and resources
- (2016) NUCLEIC ACIDS RESEARCH
- Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq
- (2016) I. Tirosh et al. SCIENCE
- Repurposing atovaquone: Targeting mitochondrial complex III and OXPHOS to eradicate cancer stem cells
- (2016) Marco Fiorillo et al. Oncotarget
- Breast Cancer-Derived Lung Metastases Show Increased Pyruvate Carboxylase-Dependent Anaplerosis
- (2016) Stefan Christen et al. Cell Reports
- The phasor-FLIM fingerprints reveal shifts from OXPHOS to enhanced glycolysis in Huntington Disease
- (2016) Sara Sameni et al. Scientific Reports
- Enhanced OXPHOS, glutaminolysis and -oxidation constitute the metastatic phenotype of melanoma cells
- (2015) M. F. Rodrigues et al. BIOCHEMICAL JOURNAL
- Prognostic and functional importance of the engraftment-associated genes in the patient-derived xenograft models of triple-negative breast cancers
- (2015) Hyeong-Gon Moon et al. BREAST CANCER RESEARCH AND TREATMENT
- Plumbagin Inhibits Prostate Carcinogenesis in Intact and Castrated PTEN Knockout Mice via Targeting PKC , Stat3, and Epithelial-to-Mesenchymal Transition Markers
- (2015) B. B. Hafeez et al. Cancer Prevention Research
- High-Resolution Metabolomics with Acyl-CoA Profiling Reveals Widespread Remodeling in Response to Diet
- (2015) Xiaojing Liu et al. MOLECULAR & CELLULAR PROTEOMICS
- Single-cell analysis reveals a stem-cell program in human metastatic breast cancer cells
- (2015) Devon A. Lawson et al. NATURE
- Spatial reconstruction of single-cell gene expression data
- (2015) Rahul Satija et al. NATURE BIOTECHNOLOGY
- Metastatic Stem Cells: Sources, Niches, and Vital Pathways
- (2014) Thordur Oskarsson et al. Cell Stem Cell
- Metabolic shifts toward glutamine regulate tumor growth, invasion and bioenergetics in ovarian cancer
- (2014) L. Yang et al. Molecular Systems Biology
- The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells
- (2014) Cole Trapnell et al. NATURE BIOTECHNOLOGY
- PGC-1α mediates mitochondrial biogenesis and oxidative phosphorylation in cancer cells to promote metastasis
- (2014) Valerie S. LeBleu et al. NATURE CELL BIOLOGY
- Elevation of circulating branched-chain amino acids is an early event in human pancreatic adenocarcinoma development
- (2014) Jared R Mayers et al. NATURE MEDICINE
- Full-length RNA-seq from single cells using Smart-seq2
- (2014) Simone Picelli et al. Nature Protocols
- Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma
- (2014) A. P. Patel et al. SCIENCE
- A Mitochondrial Switch Promotes Tumor Metastasis
- (2014) Paolo E. Porporato et al. Cell Reports
- Mitochondrial c-Src regulates cell survival through phosphorylation of respiratory chain components
- (2012) Masato Ogura et al. BIOCHEMICAL JOURNAL
- Metformin and breast cancer risk: a meta-analysis and critical literature review
- (2012) Nananda F. Col et al. BREAST CANCER RESEARCH AND TREATMENT
- Metformin intake is associated with better survival in ovarian cancer
- (2012) Sanjeev Kumar et al. CANCER
- Plumbagin inhibits prostate cancer development in TRAMP mice via targeting PKC , Stat3 and neuroendocrine markers
- (2012) B. B. Hafeez et al. CARCINOGENESIS
- Migration of MDA-MB-231 breast cancer cells depends on the availability of exogenous lipids and cholesterol esterification
- (2011) Caryl J. Antalis et al. CLINICAL & EXPERIMENTAL METASTASIS
- Use of metformin and the risk of ovarian cancer: A case–control analysis
- (2011) Michael Bodmer et al. GYNECOLOGIC ONCOLOGY
- Tumor grafts derived from women with breast cancer authentically reflect tumor pathology, growth, metastasis and disease outcomes
- (2011) Yoko S DeRose et al. NATURE MEDICINE
- Relationship of Type II Diabetes and Metformin Use to Ovarian Cancer Progression, Survival, and Chemosensitivity
- (2011) Iris L. Romero et al. OBSTETRICS AND GYNECOLOGY
- Oligomycin-induced Bioenergetic Adaptation in Cancer Cells with Heterogeneous Bioenergetic Organization
- (2010) Wenshan Hao et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients
- (2009) Balazs Györffy et al. BREAST CANCER RESEARCH AND TREATMENT
- Bioenergetic analysis of isolated cerebrocortical nerve terminals on a microgram scale: spare respiratory capacity and stochastic mitochondrial failure
- (2009) Sung W. Choi et al. JOURNAL OF NEUROCHEMISTRY
- Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment
- (2009) Zachary T. Schafer et al. NATURE
- Redox regulation of anoikis: reactive oxygen species as essential mediators of cell survival
- (2008) E Giannoni et al. CELL DEATH AND DIFFERENTIATION
- “ROS-generating mitochondrial DNA mutations can regulate tumor cell metastasis”—a critical commentary
- (2008) J ZIELONKA et al. FREE RADICAL BIOLOGY AND MEDICINE
- Activation of HIF-1α in exponentially growing cells via hypoxic stimulation is independent of the Akt/mTOR pathway
- (2008) Frédéric Dayan et al. JOURNAL OF CELLULAR PHYSIOLOGY
- The Phasor Approach to Fluorescence Lifetime Imaging Analysis
- (2007) Michelle A. Digman et al. BIOPHYSICAL JOURNAL
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now