Development of novel indolin-2-one derivative incorporating thiazole moiety as DHFR and quorum sensing inhibitors: Synthesis, antimicrobial, and antibiofilm activities with molecular modelling study

An Overview of the Synthesis and Antimicrobial, Antiprotozoal, and Antitumor Activity of Thiazole and Bisthiazole Derivatives

(2021) Anca-Maria Borcea et al.   MOLECULES

Novel Structural hybrids of quinolone and thiazole moieties: Synthesis and evaluation of antibacterial and antifungal activities with molecular modeling studies

(2021) Sally I. Eissa et al.   BIOORGANIC CHEMISTRY

Development of adamantane scaffold containing 1,3,4-thiadiazole derivatives: design, synthesis, anti-proliferative activity and molecular docking study targeting EGFR

(2021) Mohammed M. S. Wassel et al.   BIOORGANIC CHEMISTRY

5-Substituted isatin thiosemicarbazones as inhibitors of tyrosinase: Insights of substituent effects

(2021) Run Cheng et al.   SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY

Does Fluoroquinolones and Third-Generation Cephalosporins Restriction Reverse Extended-Spectrum β-Lactamases Klebsiella pneumoniae Resistance Rates?

(2021) Mirjana Stanić Benić et al.   Microbial Drug Resistance

Isatin-derived azoles as new potential antimicrobial agents: Design, synthesis and biological evaluation

(2021) Vijai Kumar Reddy Tangadanchu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Design, synthesis of new magenta dyestuffs based on thiazole azomethine disperse reactive dyes with antibacterial potential on both dyes and gamma-irradiated dyed fabric

(2021) Seham A. Ibrahim et al.   DYES AND PIGMENTS

UPLC-ESI-MS/MS profiling of the underground parts of common Iris species in relation to their anti-virulence activities against Staphylococcus aureus

(2021) Mona M. Okba et al.   JOURNAL OF ETHNOPHARMACOLOGY

Design, synthesis, antiproliferative evaluation, and molecular docking study of new quinoxaline derivatives as apoptotic inducers and EGFR inhibitors

(2021) Eman A. Fayed et al.   JOURNAL OF MOLECULAR STRUCTURE

HPLC-PDA-ESI-MS/MS Profiling and Anti-Biofilm Potential of Eucalyptussideroxylon Flowers

(2021) Mona M. Okba et al.   Antibiotics-Basel

In vivo screening and toxicity studies of indolinone incorporated thiosemicarbazone, thiazole and piperidinosulfonyl moieties as anticonvulsant agents

(2021) Eman A. Fayed et al.   BIOORGANIC CHEMISTRY

Hydrazonoyl bromide precursors as DHFR inhibitors for the synthesis of bis-thiazolyl pyrazole derivatives; antimicrobial activities, antibiofilm, and drug combination studies against MRSA

(2021) Seham A. Ibrahim et al.   BIOORGANIC CHEMISTRY

Novel benzenesulfonamides aryl and arylsulfone conjugates adopting tail/dual tail approaches: Synthesis, carbonic anhydrase inhibitory activity and molecular modeling studies

(2021) Assem H. Eldeeb et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Discovery of metal-based complexes as promising antimicrobial agents

(2021) Jing Liang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Therapeutic strategies for Covid-19 based on molecular docking and dynamic studies to the ACE-2 receptors, Furin, and viral spike proteins

(2021) Essam S. A. E. H. Khattab et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

One-pot strategy for thiazole tethered 7-ethoxy quinoline hybrids: Synthesis and potential antimicrobial agents as dihydrofolate reductase (DHFR) inhibitors with molecular docking study

(2021) Yousry A. Ammar et al.   JOURNAL OF MOLECULAR STRUCTURE

Experimental and theoretical investigation for 6-Morpholinosulfonylquinoxalin-2(1H)-one and its haydrazone derivate: Synthesis, characterization, tautomerization and antimicrobial evaluation

(2021) Doaa M. Elsisi et al.   JOURNAL OF MOLECULAR STRUCTURE

Design, synthesis of new novel quinoxalin-2(1H)-one derivatives incorporating hydrazone, hydrazine, and pyrazole moieties as antimicrobial potential with in-silico ADME and molecular docking simulation

(2021) Ahmed Ragab et al.   Arabian Journal of Chemistry

Design, synthesis, in vitro antimicrobial evaluation and molecular docking studies of indol-2-one tagged with morpholinosulfonyl moiety as DNA gyrase inhibitors

(2020) Mohamed A. Salem et al.   BIOORGANIC CHEMISTRY

The Lancet Infectious Diseases Commission on antimicrobial resistance: 6 years later

(2020) Ramanan Laxminarayan et al.   LANCET INFECTIOUS DISEASES

Design, synthesis, biological evaluation and molecular docking study based on novel fused pyrazolothiazole scaffold

(2020) Hala F. Rizk et al.   Journal of the Iranian Chemical Society

Resisting antimicrobial resistance

(2020) Carl Nathan   NATURE REVIEWS MICROBIOLOGY

The rational design, synthesis, and antimicrobial investigation of 2-Amino-4-Methylthiazole analogues inhibitors of GlcN-6-P synthase

(2020) Abdelsattar M. Omar et al.   BIOORGANIC CHEMISTRY

Antimicrobial evaluation of thiadiazino and thiazolo quinoxaline hybrids as potential DNA gyrase inhibitors; design, synthesis, characterization and morphological studies

(2020) Yousry A. Ammar et al.   BIOORGANIC CHEMISTRY

In vitro cytotoxic activity of thiazole-indenoquinoxaline hybrids as apoptotic agents, design, synthesis, physicochemical and pharmacokinetic studies

(2020) Eman A. Fayed et al.   BIOORGANIC CHEMISTRY

Discovery of New Schiff Bases Tethered Pyrazole Moiety: Design, Synthesis, Biological Evaluation, and Molecular Docking Study as Dual Targeting DHFR/DNA Gyrase Inhibitors with Immunomodulatory Activity

(2020) Ashraf S. Hassan et al.   MOLECULES

Transmission of Antibiotic Resistant Bacteria and Genes: Unveiling the Jigsaw Pieces of a One Health Problem

(2020) Carla Novais et al.   Pathogens

New pyrazole‐4‐carbothioamide‐based metal complexes: Synthesis, spectral characterization, computational, antimicrobial, and antitumor investigations

(2020) Ahmed M. Ramadan et al.   APPLIED ORGANOMETALLIC CHEMISTRY

Determination of potential inhibitors based on isatin derivatives against SARS-CoV-2 main protease (mpro): a molecular docking, molecular dynamics and structure-activity relationship studies

(2020) Vishnu Nayak Badavath et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Thiazole Analogues of the Marine Alkaloid Nortopsentin as Inhibitors of Bacterial Biofilm Formation

(2020) Anna Carbone et al.   MOLECULES

Novel Schiff base-bridged multi-component sulfonamide imidazole hybrids as potentially highly selective DNA-targeting membrane active repressors against methicillin-resistant Staphylococcus aureus

(2020) Yuanyuan Hu et al.   BIOORGANIC CHEMISTRY

First Evidence of the Cysteine and Glutathione Conjugates of 3-Sulfanylpentan-1-ol in Hop (Humulus lupulus L.)

(2019) Cécile Chenot et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Design, synthesis, molecular docking and biological activity evaluation of some novel indole derivatives as potent anticancer active agents and apoptosis inducers

(2019) Ahmed M. Sh. El-Sharief et al.   BIOORGANIC CHEMISTRY

Biofilms: Novel Strategies Based on Antimicrobial Peptides

(2019) Emilia Galdiero et al.   Pharmaceutics

Synthesis, antimicrobial activity, and determination of the lipophilicity of ((cyclohex-3-enylmethylene)hydrazinyl)thiazole derivatives

(2019) Anna Biernasiuk et al.   MEDICINAL CHEMISTRY RESEARCH

Nanoparticle–Biofilm Interactions: The Role of the EPS Matrix

(2019) Stephanie Fulaz et al.   TRENDS IN MICROBIOLOGY

Crisis of Antimicrobial Resistance in China: Now and the Future

(2019) Junyan Qu et al.   Frontiers in Microbiology

A new exploration towards aminothiazolquinolone oximes as potentially multi-targeting antibacterial agents: Design, synthesis and evaluation acting on microbes, DNA, HSA and topoisomerase IV

(2019) Liang-Liang Wang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design, synthesis and biological evaluation of novel diazaspiro[4.5]decan-1-one derivatives as potential chitin synthase inhibitors and antifungal agents

(2019) Bing Li et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Antibacterial, antibiofilm and molecular modeling study of some antitumor thiazole based chalcones as a new class of DHFR inhibitors

(2019) Waad D. Alrohily et al.   MICROBIAL PATHOGENESIS

One-pot synthesis and molecular docking of some new spiropyranindol-2-one derivatives as immunomodulatory agents and in vitro antimicrobial potential with DNA gyrase inhibitor

(2019) Mohamed A. Salem et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Investigation of photophysical behaviours and antimicrobial activity of novel benzo-15-crown-5 substituted coumarin and chromone derivatives

(2019) Duygu Şahin Gül et al.   JOURNAL OF MOLECULAR STRUCTURE

Design, synthesis, antiproliferative activity, molecular docking and cell cycle analysis of some novel (morpholinosulfonyl) isatins with potential EGFR inhibitory activity

(2018) Yousry A. Ammar et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Antimicrobial peptides and their interaction with biofilms of medically relevant bacteria

(2016) Giovanna Batoni et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Antitumor and immunomodulatory activities of thiosemicarbazones and 1,3-Thiazoles in Jurkat and HT-29 cells

(2016) Thiago André R. dos Santos et al.   BIOMEDICINE & PHARMACOTHERAPY

New Imidazolidineiminothione, Imidazolidin-2-one and Imidazoquinoxaline Derivatives: Synthesis and Evaluation of Antibacterial and Antifungal Activities

(2016) Yousry A. Ammar et al.   CURRENT ORGANIC SYNTHESIS

Synthesis and anti-cancer activity evaluation of 5-(2-carboxyethenyl)-isatin derivatives

(2016) Yu-Ou Teng et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

New 1,3-diaryl-5-thioxo-imidazolidin-2,4-dione derivatives: synthesis, reactions and evaluation of antibacterial and antifungal activities

(2016) Marwa A.M.Sh. El-Sharief et al.   ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES

Recent applications of 1,3-thiazole core structure in the identification of new lead compounds and drug discovery

(2015) Adile Ayati et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Discovery of acylurea isosteres of 2-acylaminothiadiazole in the azaxanthene series of glucocorticoid receptor agonists

(2014) Hua Gong et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Recent Progress on Routes to Spirooxindole Systems Derived from Isatin

(2013) Min Xia et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

Enhanced bactericidal action of SnO2 nanostructures having different morphologies under visible light: Influence of surfactant

(2013) Nasrin Talebian et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Isatins As Privileged Molecules in Design and Synthesis of Spiro-Fused Cyclic Frameworks

(2012) Girija S. Singh et al.   CHEMICAL REVIEWS

Design, synthesis and in vitro evaluation of tetrahydropyrimidine–isatin hybrids as potential antitubercular and antimalarial agents

(2012) Tarunkumar Nanjibhai Akhaja et al.   CHINESE CHEMICAL LETTERS

Strategies for the enantioselective synthesis of spirooxindoles

(2012) Nicolas R. Ball-Jones et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Synthesis of mono, bis-2-(2-arylideneaminophenyl) indole azomethines as potential antimicrobial agents

(2011) Rondla Rohini et al.   ARCHIVES OF PHARMACAL RESEARCH

Novel Orally Active Antimalarial Thiazoles

(2011) Diego González Cabrera et al.   JOURNAL OF MEDICINAL CHEMISTRY

Inhibition of monoamine oxidase by selected C5- and C6-substituted isatin analogues

(2010) Clarina I. Manley-King et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis, anti-bacterial and anti-fungal activities of some novel Schiff bases containing 2,4-disubstituted thiazole ring

(2009) S.K. Bharti et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY