Evolution of the Ferric Reductase Domain (FRD) Superfamily: Modularity, Functional Diversification, and Signature Motifs

Mice Deficient in Dual Oxidase Maturation Factors Are Severely Hypothyroid

(2012) Helmut Grasberger et al.   MOLECULAR ENDOCRINOLOGY

Transcriptome Sequencing Identifies SPL7-Regulated Copper Acquisition Genes FRO4/FRO5 and the Copper Dependence of Iron Homeostasis in Arabidopsis

(2012) M. Bernal et al.   PLANT CELL

Yno1p/Aim14p, a NADPH-oxidase ortholog, controls extramitochondrial reactive oxygen species generation, apoptosis, and actin cable formation in yeast

(2012) M. Rinnerthaler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epithelial Nitration by a Peroxidase/NOX5 System Mediates Mosquito Antiplasmodial Immunity

(2012) G. d. A. Oliveira et al.   SCIENCE

Innate Antifungal Immunity: The Key Role of Phagocytes

(2011) Gordon D. Brown   Annual Review of Immunology

Conceptual framework and pilot study to benchmark phylogenomic databases based on reference gene trees

(2011) B. Boeckmann et al.   BRIEFINGS IN BIOINFORMATICS

Essential Role of Duox in Stabilization ofDrosophilaWing

(2011) Nguyen Thi Tu Anh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NOX Isoforms and Reactive Oxygen Species in Vascular Health

(2011) R. M. Touyz et al.   MOLECULAR INTERVENTIONS

Germline CYBB mutations that selectively affect macrophages in kindreds with X-linked predisposition to tuberculous mycobacterial disease

(2011) Jacinta Bustamante et al.   NATURE IMMUNOLOGY

SignalP 4.0: discriminating signal peptides from transmembrane regions

(2011) Thomas Nordahl Petersen et al.   NATURE METHODS

InterPro in 2011: new developments in the family and domain prediction database

(2011) S. Hunter et al.   NUCLEIC ACIDS RESEARCH

The Pfam protein families database

(2011) M. Punta et al.   NUCLEIC ACIDS RESEARCH

Targeting Vascular NADPH Oxidase 1 Blocks Tumor Angiogenesis through a PPARα Mediated Mechanism

(2011) Sarah Garrido-Urbani et al.   PLoS One

NADPH Oxidase-2 Derived ROS Dictates Murine DC Cytokine-Mediated Cell Fate Decisions during CD4 T Helper-Cell Commitment

(2011) Meghan A. Jendrysik et al.   PLoS One

UniProt Knowledgebase: a hub of integrated protein data

(2011) M. Magrane et al.   Database-The Journal of Biological Databases and Curation

Duox, Flotillin-2, and Src42A Are Required to Activate or Delimit the Spread of the Transcriptional Response to Epidermal Wounds in Drosophila

(2011) Michelle T. Juarez et al.   PLoS Genetics

BLAST-EXPLORER helps you building datasets for phylogenetic analysis

(2010) Alexis Dereeper et al.   BMC EVOLUTIONARY BIOLOGY

Bile Acid Reflux Contributes to Development of Esophageal Adenocarcinoma via Activation of Phosphatidylinositol-Specific Phospholipase C 2 and NADPH Oxidase NOX5-S

(2010) J. Hong et al.   CANCER RESEARCH

Dual oxidase, hydrogen peroxide and thyroid diseases

(2010) Hidemi Ohye et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Nox enzymes from fungus to fly to fish and what they tell us about Nox function in mammals

(2010) Jesús Aguirre et al.   FREE RADICAL BIOLOGY AND MEDICINE

Urothelial cells produce hydrogen peroxide through the activation of Duox1

(2010) Ágnes Donkó et al.   FREE RADICAL BIOLOGY AND MEDICINE

The Nox/Ferric reductase/Ferric reductase-like families of Eumycetes

(2010) Ibtissem Grissa et al.   Fungal Biology

Reactive Oxygen Species Generated by NADPH Oxidase 2 and 4 Are Required for Chondrogenic Differentiation

(2010) Ki Soon Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Redox Cycling in Iron Uptake, Efflux, and Trafficking

(2010) Daniel J. Kosman   JOURNAL OF BIOLOGICAL CHEMISTRY

Perturbed Heme Binding Is Responsible for the Blistering Phenotype Associated with Mutations in theCaenorhabditis elegansDual Oxidase 1 (DUOX1) Peroxidase Domain

(2010) Jennifer L. Meitzler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

GUIDANCE: a web server for assessing alignment confidence scores

(2010) O. Penn et al.   NUCLEIC ACIDS RESEARCH

A Peroxidase/Dual Oxidase System Modulates Midgut Epithelial Immunity in Anopheles gambiae

(2010) S. Kumar et al.   SCIENCE

Hydrogen Peroxide as a Cell-Survival Signaling Molecule

(2009) Gillian Groeger et al.   ANTIOXIDANTS & REDOX SIGNALING

Jalview Version 2--a multiple sequence alignment editor and analysis workbench

(2009) A. M. Waterhouse et al.   BIOINFORMATICS

Ce-Duox1/BLI-3 Generates Reactive Oxygen Species as a Protective Innate Immune Mechanism in Caenorhabditis elegans

(2009) V. Chavez et al.   INFECTION AND IMMUNITY

Understanding the Functional Roles of Amino Acid Residues in Enzyme Catalysis

(2009) Gemma L. Holliday et al.   JOURNAL OF MOLECULAR BIOLOGY

Functions and regulation of the Nox family in the filamentous fungusPodospora anserina: a new role in cellulose degradation

(2009) Sylvain Brun et al.   MOLECULAR MICROBIOLOGY

A tissue-scale gradient of hydrogen peroxide mediates rapid wound detection in zebrafish

(2009) Philipp Niethammer et al.   NATURE

The Pfam protein families database

(2009) Robert D. Finn et al.   NUCLEIC ACIDS RESEARCH

Iron uptake mechanisms in plants: Functions of the FRO family of ferric reductases

(2009) Jeeyon Jeong et al.   PLANT SCIENCE

Recent developments in the MAFFT multiple sequence alignment program

(2008) K. Katoh et al.   BRIEFINGS IN BIOINFORMATICS

NADPH Oxidases NOX-1 and NOX-2 Require the Regulatory Subunit NOR-1 To Control Cell Differentiation and Growth inNeurospora crassa

(2008) Nallely Cano-Domínguez et al.   EUKARYOTIC CELL

Structure, regulation and evolution of Nox-family NADPH oxidases that produce reactive oxygen species

(2008) Hideki Sumimoto   FEBS Journal

Inherent flexibility and protein function: The open/closed conformational transition in the N-terminal domain of calmodulin

(2008) Swarnendu Tripathi et al.   JOURNAL OF CHEMICAL PHYSICS

The Deep Archaeal Roots of Eukaryotes

(2008) N. Yutin et al.   MOLECULAR BIOLOGY AND EVOLUTION

An Improved General Amino Acid Replacement Matrix

(2008) S. Q. Le et al.   MOLECULAR BIOLOGY AND EVOLUTION

NADPH Oxidases Are Involved in Differentiation and Pathogenicity in Botrytis cinerea

(2008) Nadja Segmüller et al.   MOLECULAR PLANT-MICROBE INTERACTIONS

Phylogeny.fr: robust phylogenetic analysis for the non-specialist

(2008) A. Dereeper et al.   NUCLEIC ACIDS RESEARCH

NCBI BLAST: a better web interface

(2008) M. Johnson et al.   NUCLEIC ACIDS RESEARCH

The FRO2 ferric reductase is required for glycine betaine’s effect on chilling tolerance inArabidopsisroots

(2008) John Einset et al.   PHYSIOLOGIA PLANTARUM

Chloroplast Fe(III) chelate reductase activity is essential for seedling viability under iron limiting conditions

(2008) J. Jeong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA