BJ-1108, a 6-Amino-2,4,5-Trimethylpyridin-3-ol Analog, Inhibits Serotonin-Induced Angiogenesis and Tumor Growth through PI3K/NOX Pathway

Inhibitory effect of Samul-tang on retinal neovascularization in oxygen-induced retinopathy

(2015) Yun Mi Lee et al.   BMC Complementary and Alternative Medicine

NOX1 to NOX2 switch deactivates AMPK and induces invasive phenotype in colon cancer cells through overexpression of MMP-7

(2015) Suhrid Banskota et al.   Molecular Cancer

Depletion of Serotonin and Selective Inhibition of 2B Receptor Suppressed Tumor Angiogenesis by Inhibiting Endothelial Nitric Oxide Synthase and Extracellular Signal-Regulated Kinase 1/2 Phosphorylation

(2015) Masanori Asada et al.   NEOPLASIA

Anti-angiogenic activity of macrolactin A and its succinyl derivative is mediated through inhibition of class I PI3K activity and its signaling

(2014) Youra Kang et al.   ARCHIVES OF PHARMACAL RESEARCH

Synthesis and antiangiogenic activity of 6-amido-2,4,5-trimethylpyridin-3-ols

(2014) Hyunji Lee et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

6-Amino-2,4,5-trimethylpyridin-3-ols: A new general synthetic route and antiangiogenic activity

(2014) Dong-Guk Kim et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Serotonin regulates innate immune responses of colon epithelial cells through Nox2-derived reactive oxygen species

(2014) Sushil Chandra Regmi et al.   FREE RADICAL BIOLOGY AND MEDICINE

The vascular permeabilizing factors histamine and serotonin induce angiogenesis through TR3/Nur77 and subsequently truncate it through thrombospondin-1

(2013) L. Qin et al.   BLOOD

Phosphatidylinositol 3-kinase (PI3K) inhibitors as cancer therapeutics

(2013) Akintunde Akinleye et al.   Journal of Hematology & Oncology

Serotonin activates angiogenic phosphorylation signaling in human endothelial cells

(2012) Ali Zamani et al.   FEBS LETTERS

Role of serotonin in angiogenesis: Induction of angiogenesis by sarpogrelate via endothelial 5-HT1B/Akt/eNOS pathway in diabetic mice

(2011) Masaaki Iwabayashi et al.   ATHEROSCLEROSIS

PI3K/AKT/mTOR Pathway in Angiogenesis

(2011) Jayashree Karar et al.   Frontiers in Molecular Neuroscience

Preparation and Investigation of Vitamin B6-Derived Aminopyridinol Antioxidants

(2010) Remigiusz Serwa et al.   CHEMISTRY-A EUROPEAN JOURNAL

Action of 6-amino-3-pyridinols as novel antioxidants against free radicals and oxidative stress in solution, plasma, and cultured cells

(2010) Yo Omata et al.   FREE RADICAL BIOLOGY AND MEDICINE

The platelet contribution to cancer progression

(2010) N. M. BAMBACE et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Serotonin promotes tumor growth in human hepatocellular cancer

(2009) Christopher Soll et al.   HEPATOLOGY

Troglitazone Inhibits Vascular Endothelial Growth Factor–Induced Angiogenic Signaling via Suppression of Reactive Oxygen Species Production and Extracellular Signal–Regulated Kinase Phosphorylation in Endothelial Cells

(2009) Byung Chul Park et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Inhibitory effect of simvastatin on the TNF-α- and angiotensin II-induced monocyte adhesion to endothelial cells is mediated through the suppression of geranylgeranyl isoprenoid-dependent ROS generation

(2008) Su-Young Park et al.   ARCHIVES OF PHARMACAL RESEARCH

Reactive oxygen species and angiogenesis: NADPH oxidase as target for cancer therapy

(2008) Masuko Ushio-Fukai et al.   CANCER LETTERS

Serotonin Regulates Macrophage-Mediated Angiogenesis in a Mouse Model of Colon Cancer Allografts

(2008) A. Nocito et al.   CANCER RESEARCH

Clotrimazole Ameliorates Intestinal Inflammation and Abnormal Angiogenesis by Inhibiting Interleukin-8 Expression through a Nuclear Factor- B-Dependent Manner

(2008) D. Thapa et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Correlation between antiangiogenic activity and antioxidant activity of various components from propolis

(2008) Mok-Ryeon Ahn et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Angiogenesis selectively requires the p110α isoform of PI3K to control endothelial cell migration

(2008) Mariona Graupera et al.   NATURE

The p110  isoform of phosphoinositide 3-kinase signals downstream of G protein-coupled receptors and is functionally redundant with p110 

(2008) J. Guillermet-Guibert et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA