NADPH Oxidase-Related Pathophysiology in Experimental Models of Stroke

Organizers and activators: Cytosolic Nox proteins impacting on vascular function

(2017) Katrin Schröder et al.   FREE RADICAL BIOLOGY AND MEDICINE

NADPH oxidases as drug targets and biomarkers in neurodegenerative diseases: What is the evidence?

(2017) Silvia Sorce et al.   FREE RADICAL BIOLOGY AND MEDICINE

The Role of Neurogenic Inflammation in Blood-Brain Barrier Disruption and Development of Cerebral Oedema Following Acute Central Nervous System (CNS) Injury

(2017) et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

NADPH oxidase in brain injury and neurodegenerative disorders

(2017) Merry W. Ma et al.   Molecular Neurodegeneration

Early Reperfusion After Brain Ischemia Has Beneficial Effects Beyond Rescuing Neurons

(2017) Masaki Tachibana et al.   STROKE

Acute Stroke Imaging Research Roadmap III Imaging Selection and Outcomes in Acute Stroke Reperfusion Clinical Trials

(2016) Steven J. Warach et al.   STROKE

Effect of p22phox depletion on sympathetic regulation of blood pressure in SHRSP: evaluation in a new congenic strain

(2016) Hasan M. Zahid et al.   Scientific Reports

Involvement of platelet-derived growth factor receptor β in fibrosis through extracellular matrix protein production after ischemic stroke

(2015) Noriko Makihara et al.   EXPERIMENTAL NEUROLOGY

Detrimental role of pericyte Nox4 in the acute phase of brain ischemia

(2015) Ataru Nishimura et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

What is a pericyte?

(2015) David Attwell et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Nox4 Is a Major Source of Superoxide Production in Human Brain Pericytes

(2015) Junya Kuroda et al.   JOURNAL OF VASCULAR RESEARCH

Role of Neuronal NADPH Oxidase 1 in the Peri-Infarct Regions after Stroke

(2015) Dong-Hee Choi et al.   PLoS One

Focal Ischemic Injury with Complex Middle Cerebral Artery in Stroke-Prone Spontaneously Hypertensive Rats with Loss-Of-Function in NADPH Oxidases

(2015) Hiroshi Yao et al.   PLoS One

Nox2 Knockout Delays Infarct Progression and Increases Vascular Recovery through Angiogenesis in Mice following Ischaemic Stroke with Reperfusion

(2014) Sarah K. McCann et al.   PLoS One

Hemorrhagic Transformation after Ischemic Stroke in Animals and Humans

(2013) Glen C Jickling et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The role of extracellular matrix in vascular branching morphogenesis

(2013) Amel Mettouchi   Cell Adhesion & Migration

Brain infarct volume after permanent focal ischemia is not dependent on Nox2 expression

(2012) Hyun Ah Kim et al.   BRAIN RESEARCH

Nox4 Is a Protective Reactive Oxygen Species Generating Vascular NADPH Oxidase

(2012) Katrin Schröder et al.   CIRCULATION RESEARCH

Biochemistry, Physiology, and Pathophysiology of NADPH Oxidases in the Cardiovascular System

(2012) Bernard Lassègue et al.   CIRCULATION RESEARCH

Penumbral Imaging by Using Perfusion Computed Tomography and Perfusion-Weighted Magnetic Resonance Imaging: Current Concepts

(2012) Makoto Sasaki et al.   Journal of Stroke & Cerebrovascular Diseases

Standards and pitfalls of focal ischemia models in spontaneously hypertensive rats: With a systematic review of recent articles

(2012) Hiroshi Yao et al.   Journal of Translational Medicine

Endothelial Nox4 NADPH Oxidase Enhances Vasodilatation and Reduces Blood Pressure In Vivo

(2011) Robin Ray et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

NADPH Oxidase 4 Promotes Endothelial Angiogenesis Through Endothelial Nitric Oxide Synthase Activation

(2011) Siobhan M. Craige et al.   CIRCULATION

Pathophysiological Roles of NADPH Oxidase/Nox Family Proteins in the Vascular System

(2011) Tetsuro Ago et al.   CIRCULATION JOURNAL

Pericytes: Developmental, Physiological, and Pathological Perspectives, Problems, and Promises

(2011) Annika Armulik et al.   DEVELOPMENTAL CELL

The Infarct Core is Well Represented by the Acute Diffusion Lesion: Sustained Reversal is Infrequent

(2011) Bruce CV Campbell et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

NADPH oxidase is involved in post-ischemic brain inflammation

(2011) Hai Chen et al.   NEUROBIOLOGY OF DISEASE

Nox2 Oxidase Activity Accounts for the Oxidative Stress and Vasomotor Dysfunction in Mouse Cerebral Arteries following Ischemic Stroke

(2011) T. Michael De Silva et al.   PLoS One

A Pericyte Origin of Spinal Cord Scar Tissue

(2011) C. Goritz et al.   SCIENCE

Zinc-finger nucleases: new strategies to target the rat genome

(2010) Aron M. Geurts et al.   CLINICAL SCIENCE

Different Strokes for Different Folks: The Rich Diversity of Animal Models of Focal Cerebral Ischemia

(2010) David W Howells et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Mechanisms Contributing to Cerebral Infarct Size after Stroke: Gender, Reperfusion, T Lymphocytes, and Nox2-Derived Superoxide

(2010) Vanessa H Brait et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The NADPH Oxidase Subunit NOX4 Is a New Target Gene of the Hypoxia-inducible Factor-1

(2010) Isabel Diebold et al.   MOLECULAR BIOLOGY OF THE CELL

NADPH oxidase Nox1 contributes to ischemic injury in experimental stroke in mice

(2010) Timo Kahles et al.   NEUROBIOLOGY OF DISEASE

Fractal analysis of retinal vessels suggests that a distinct vasculopathy causes lacunar stroke

(2010) F. N. Doubal et al.   NEUROLOGY

The Benefits of Intravenous Thrombolysis Relate to the Site of Baseline Arterial Occlusion in the Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET)

(2010) Deidre A. De Silva et al.   STROKE

Post-Stroke Inhibition of Induced NADPH Oxidase Type 4 Prevents Oxidative Stress and Neurodegeneration

(2010) Christoph Kleinschnitz et al.   PLOS BIOLOGY

Importance of NOX1 for angiotensin II-induced cerebrovascular superoxide production and cortical infarct volume following ischemic stroke

(2009) Katherine A. Jackman et al.   BRAIN RESEARCH

Reduction of cerebral infarct volume by apocynin requires pretreatment and is absent in Nox2-deficient mice

(2009) KA Jackman et al.   BRITISH JOURNAL OF PHARMACOLOGY

Branching Morphogenesis

(2009) Arie Horowitz et al.   CIRCULATION RESEARCH

Inhibition of NADPH Oxidase is Neuroprotective after Ischemia—Reperfusion

(2009) Hai Chen et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Pivotal Advance: Eosinophilia in the MES rat strain is caused by a loss-of-function mutation in the gene for cytochrome b (-245), alpha polypeptide (Cyba )

(2009) Masayuki Mori et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Inflammatory mechanisms in ischemic stroke: therapeutic approaches

(2009) Shaheen E Lakhan et al.   Journal of Translational Medicine

Pericyte contraction induced by oxidative-nitrative stress impairs capillary reflow despite successful opening of an occluded cerebral artery

(2009) Muge Yemisci et al.   NATURE MEDICINE

NADPH oxidase-4 mediates myofibroblast activation and fibrogenic responses to lung injury

(2009) Louise Hecker et al.   NATURE MEDICINE

Reperfusion-Induced Temporary Appearance of Therapeutic Window in Penumbra after 2 h of Photothrombotic Middle Cerebral Artery Occlusion in Rats

(2008) Hiroshi Yao et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM