Transforming growth factor-β1 requires NADPH oxidase 4 for angiogenesisin vitroandin vivo

The Nox4 Inhibitor GKT137831 Attenuates Hypoxia-Induced Pulmonary Vascular Cell Proliferation

(2012) David E. Green et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

TGF-β signalling and its role in cancer progression and metastasis

(2012) Yvette Drabsch et al.   CANCER AND METASTASIS REVIEWS

Nox4 Is a Protective Reactive Oxygen Species Generating Vascular NADPH Oxidase

(2012) Katrin Schröder et al.   CIRCULATION RESEARCH

Nox4 involvement in TGF-beta and SMAD3-driven induction of the epithelial-to-mesenchymal transition and migration of breast epithelial cells

(2012) Howard E. Boudreau et al.   FREE RADICAL BIOLOGY AND MEDICINE

Endothelial expression of hypoxia-inducible factor 1 protects the murine heart and aorta from pressure overload by suppression of TGF-  signaling

(2012) H. Wei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Key Role for NOX4 in Epithelial Cell Death During Development of Lung Fibrosis

(2011) Stephanie Carnesecchi et al.   ANTIOXIDANTS & REDOX SIGNALING

NOX1, 2, 4, 5: counting out oxidative stress

(2011) K Wingler et al.   BRITISH JOURNAL OF PHARMACOLOGY

NADPH Oxidase 4 Promotes Endothelial Angiogenesis Through Endothelial Nitric Oxide Synthase Activation

(2011) Siobhan M. Craige et al.   CIRCULATION

Nox4 regulates Nrf2 and glutathione redox in cardiomyocytes in vivo

(2011) Alison C. Brewer et al.   FREE RADICAL BIOLOGY AND MEDICINE

The E-loop Is Involved in Hydrogen Peroxide Formation by the NADPH Oxidase Nox4

(2011) Ina Takac et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Targeting Vascular NADPH Oxidase 1 Blocks Tumor Angiogenesis through a PPARα Mediated Mechanism

(2011) Sarah Garrido-Urbani et al.   PLoS One

Hypoxia-inducible factor-1-dependent mechanisms of vascularization and vascular remodelling

(2010) S. Rey et al.   CARDIOVASCULAR RESEARCH

Upregulation of Nox4 by TGFβ1 Oxidizes SERCA and Inhibits NO in Arterial Smooth Muscle of the Prediabetic Zucker Rat

(2010) XiaoYong Tong et al.   CIRCULATION RESEARCH

NADPH oxidase 4 mediates TGF-β-induced smooth muscle α-actin via p38MAPK and serum response factor

(2010) Abel Martin-Garrido et al.   FREE RADICAL BIOLOGY AND MEDICINE

Dissecting the effect of targeting the epidermal growth factor receptor on TGF-β-induced-apoptosis in human hepatocellular carcinoma cells

(2010) Laia Caja et al.   JOURNAL OF HEPATOLOGY

NADPH oxidase-4 mediates protection against chronic load-induced stress in mouse hearts by enhancing angiogenesis

(2010) M. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NADPH oxidase 4 (Nox4) is a major source of oxidative stress in the failing heart

(2010) J. Kuroda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Post-Stroke Inhibition of Induced NADPH Oxidase Type 4 Prevents Oxidative Stress and Neurodegeneration

(2010) Christoph Kleinschnitz et al.   PLOS BIOLOGY

Diagnosis and individual treatment of cardiovascular diseases: targeting vascular oxidative stress

(2010) Melanie E Armitage et al.   Expert Review of Clinical Pharmacology

Translation-Linked mRNA Destabilization Accompanying Serum-Induced Nox4 Expression in Human Endothelial Cells

(2009) Hitesh Peshavariya et al.   ANTIOXIDANTS & REDOX SIGNALING

Novel Role of NADPH Oxidase in Angiogenesis and Stem/Progenitor Cell Function

(2009) Masuko Ushio-Fukai et al.   ANTIOXIDANTS & REDOX SIGNALING

NADPH oxidase-4 mediates myofibroblast activation and fibrogenic responses to lung injury

(2009) Louise Hecker et al.   NATURE MEDICINE

Regulation of cell proliferation by NADPH oxidase-mediated signaling: Potential roles in tissue repair, regenerative medicine and tissue engineering

(2009) Elsa C. Chan et al.   PHARMACOLOGY & THERAPEUTICS

Reactive Oxygen Species and Endothelial Activation

(2008) Sara P. Alom-Ruiz et al.   ANTIOXIDANTS & REDOX SIGNALING

Regulation of ROS signal transduction by NADPH oxidase 4 localization

(2008) Kai Chen et al.   JOURNAL OF CELL BIOLOGY