- Home
- Publications
- Publication Search
- Publication Details
Title
The Critical Role of TRIB2 in Cancer and Therapy Resistance
Authors
Keywords
-
Journal
Cancers
Volume 13, Issue 11, Pages 2701
Publisher
MDPI AG
Online
2021-05-31
DOI
10.3390/cancers13112701
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Tribbles homolog 2 promotes hepatic fibrosis and hepatocarcinogenesis through phosphatase 1A‐Mediated stabilization of yes‐associated protein
- (2021) Dejuan Xiang et al. LIVER INTERNATIONAL
- TRIB2 modulates proteasome function to reduce ubiquitin stability and protect liver cancer cells against oxidative stress
- (2021) Susu Guo et al. Cell Death & Disease
- Tribbles Pseudokinase 2 (TRIB2) Regulates Expression of Binding Partners in Bovine Granulosa Cells
- (2021) Aly Warma et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Proteolysis-Targeting Chimeras as Therapeutics and Tools for Biological Discovery
- (2020) George M. Burslem et al. CELL
- Cataloguing the dead: breathing new life into pseudokinase research
- (2020) Safal Shrestha et al. FEBS Journal
- Knockdown of circ_0084043 suppresses the development of human melanoma cells through miR-429/tribbles homolog 2 axis and Wnt/β-catenin pathway
- (2020) Zhibing Chen et al. LIFE SCIENCES
- The Drug-Resistance Mechanisms of Five Platinum-Based Antitumor Agents
- (2020) Jiabei Zhou et al. Frontiers in Pharmacology
- Severe metabolic alterations in liver cancer lead to ERK pathway activation and drug resistance
- (2020) Zeribe Chike Nwosu et al. EBioMedicine
- LncRNA ZEB1-AS1 promotes pancreatic cancer progression by regulating miR-505-3p/TRIB2 axis
- (2020) Guohua Wei et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Whole-exome and RNA sequencing of pulmonary carcinoid reveals chromosomal rearrangements associated with recurrence
- (2020) Akihiko Miyanaga et al. LUNG CANCER
- Immunotherapy for Hepatocellular Carcinoma: A 2021 Update
- (2020) Christo Kole et al. Cancers
- Genomic and Functional Regulation of TRIB1 Contributes to Prostate Cancer Pathogenesis
- (2020) Parastoo Shahrouzi et al. Cancers
- Harmine and Piperlongumine Revert TRIB2-Mediated Drug Resistance
- (2020) Susana Machado et al. Cancers
- Combined elevation of TRIB2 and MAP3K1 indicates poor prognosis and chemoresistance to temozolomide in glioblastoma
- (2019) Jia Wang et al. CNS Neuroscience & Therapeutics
- Wnt/β-Catenin Signaling in Liver Cancers
- (2019) Wenhui Wang et al. Cancers
- Pseudokinases: a tribble‐edged sword
- (2019) Laura Richmond et al. FEBS Journal
- miR-509-5p Inhibits the Proliferation and Invasion of Osteosarcoma by Targeting TRIB2
- (2019) Jiekun Guo et al. Biomed Research International
- circRNA_0084043 promote malignant melanoma progression via miR-153-3p/Snail axis
- (2018) Wenkang Luan et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Inverse and correlative relationships between TRIBBLES genes indicate non-redundant functions during normal and malignant haemopoiesis
- (2018) Mara Salomé et al. EXPERIMENTAL HEMATOLOGY
- TRIB2 knockdown as a regulator of chemotherapy resistance and proliferation via the ERK/STAT3 signaling pathway in human chronic myelogenous leukemia K562/ADM cells
- (2018) Xiancheng Ma et al. ONCOLOGY REPORTS
- A Trib2-p38 axis controls myeloid leukaemia cell cycle and stress response signalling
- (2018) Mara Salomé et al. Cell Death & Disease
- Trib2 expression in granulocyte-monocyte progenitors drives a highly drug resistant acute myeloid leukaemia linked to elevated Bcl2
- (2018) Caitriona O'Connor et al. Oncotarget
- Hsa-miR-99b/let-7e/miR-125a Cluster Regulates Pathogen Recognition Receptor-Stimulated Suppressive Antigen-Presenting Cells
- (2018) Dagmar Hildebrand et al. Frontiers in Immunology
- Covalent inhibitors of EGFR family protein kinases induce degradation of human Tribbles 2 (TRIB2) pseudokinase in cancer cells
- (2018) Daniel M. Foulkes et al. Science Signaling
- TRIB2 functions as novel oncogene in colorectal cancer by blocking cellular senescence through AP4/p21 signaling
- (2018) Zhenlin Hou et al. Molecular Cancer
- Tribbles 2 mediates cisplatin sensitivity and DNA damage response in epithelial ovarian cancer
- (2017) Daniel Kritsch et al. INTERNATIONAL JOURNAL OF CANCER
- Tribbles in the 21st Century: The Evolving Roles of Tribbles Pseudokinases in Biology and Disease
- (2017) Patrick A. Eyers et al. TRENDS IN CELL BIOLOGY
- TRIB2 confers resistance to anti-cancer therapy by activating the serine/threonine protein kinase AKT
- (2017) Richard Hill et al. Nature Communications
- TRIB2 contributes to cisplatin resistance in small cell lung cancer
- (2017) Yuanxin Liang et al. Oncotarget
- The Oncogenic Role of Tribbles 1 in Hepatocellular Carcinoma Is Mediated by a Feedback Loop Involving microRNA-23a and p53
- (2017) Ying Ye et al. Frontiers in Physiology
- An adaptive variant of TRIB2, rs1057001, is associated with higher expression levels of thermogenic genes in human subcutaneous and visceral adipose tissues
- (2017) Kazuhiro Nakayama et al. Journal of Physiological Anthropology
- TRIB1 is a positive regulator of hepatocyte nuclear factor 4-alpha
- (2017) Sébastien Soubeyrand et al. Scientific Reports
- Role of Tribbles Pseudokinase 1 (TRIB1) in human hepatocyte metabolism
- (2016) Sébastien Soubeyrand et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Tribbles-Related Protein Family Members as Regulators or Substrates of the Ubiquitin-Proteasome System in Cancer Development
- (2016) Satoshi Sakai et al. CURRENT CANCER DRUG TARGETS
- Deregulation of the HOXA9/MEIS1 axis in acute leukemia
- (2016) Cailin T. Collins et al. CURRENT OPINION IN HEMATOLOGY
- The presence of C/EBPα and its degradation are both required for TRIB2-mediated leukaemia
- (2016) C O'Connor et al. ONCOGENE
- Trib2 Suppresses Tumor Initiation in Notch-Driven T-ALL
- (2016) Sarah J. Stein et al. PLoS One
- Smad3-related miRNAs regulated oncogenic TRIB2 promoter activity to effectively suppress lung adenocarcinoma growth
- (2016) Yan-Xia Zhang et al. Cell Death & Disease
- Murine tribbles homolog 2 deficiency affects erythroid progenitor development and confers macrocytic anemia on mice
- (2016) Kou-Ray Lin et al. Scientific Reports
- TRIB2 regulates normal and stress-induced thymocyte proliferation
- (2016) Kai Ling Liang et al. Cell Discovery
- Competition between members of the tribbles pseudokinase protein family shapes their interactions with mitogen activated protein kinase pathways
- (2016) Hongtao Guan et al. Scientific Reports
- The Tribbles 2 (TRB2) pseudokinase binds to ATP and autophosphorylates in a metal-independent manner
- (2015) Fiona P. Bailey et al. BIOCHEMICAL JOURNAL
- Tribbles pseudokinases: novel targets for chemical biology and drug discovery?
- (2015) D. M. Foulkes et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Tribbles in normal and malignant haematopoiesis
- (2015) S. J. Stein et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Tribbles role in reproduction
- (2015) S. Basatvat et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Tribbles breaking bad: TRIB2 suppresses FOXO and acts as an oncogenic protein in melanoma
- (2015) W. Link BIOCHEMICAL SOCIETY TRANSACTIONS
- The role of TRIB1 in lipid metabolism; from genetics to pathways
- (2015) S. Iwamoto et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Tribbles in inflammation
- (2015) J. Johnston et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- TRIB2 as a biomarker for diagnosis and progression of melanoma
- (2015) Richard Hill et al. CARCINOGENESIS
- TRIBBLES: A Twist in the Pseudokinase Tail
- (2015) Patrick A. Eyers STRUCTURE
- Inhibition of tribbles protein-1 attenuates radioresistance in human glioma cells
- (2015) Bo Tang et al. Scientific Reports
- Regulation of Trib2 by an E2F1-C/EBP feedback loop in AML cell proliferation
- (2014) L. Rishi et al. BLOOD
- Cisplatin in cancer therapy: Molecular mechanisms of action
- (2014) Shaloam Dasari et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- TRIB2 inhibits Wnt/β-Catenin/TCF4 signaling through its associated ubiquitin E3 ligases, β-TrCP, COP1 and Smurf1, in liver cancer cells
- (2014) Shanshan Xu et al. FEBS LETTERS
- Ubiquitin E3 ligase SCFβ-TRCP regulates TRIB2 stability in liver cancer cells
- (2013) Yongxia Qiao et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Tribbles in acute leukemia
- (2013) K. L. Liang et al. BLOOD
- COP1 targets C/EBP for degradation and induces acute myeloid leukemia via Trib1
- (2013) A. Yoshida et al. BLOOD
- Let-7c inhibits A549 cell proliferation through oncogenic TRIB2 related factors
- (2013) Ping-Yu Wang et al. FEBS LETTERS
- Impaired Phosphorylation and Ubiquitination by p70 S6 Kinase (p70S6K) and Smad Ubiquitination Regulatory Factor 1 (Smurf1) Promote Tribbles Homolog 2 (TRIB2) Stability and Carcinogenic Property in Liver Cancer
- (2013) Jiayi Wang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- TRIB2 Acts Downstream of Wnt/TCF in Liver Cancer Cells to Regulate YAP and C/EBPα Function
- (2013) Jiayi Wang et al. MOLECULAR CELL
- Intrinsic and Acquired Drug Resistance in Malignant Tumors
- (2012) Theodor Lippert et al. ARZNEIMITTEL-FORSCHUNG-DRUG RESEARCH
- Elevated TRIB2 with NOTCH1 activation in paediatric/adult T-ALL
- (2012) Maura M. Hannon et al. BRITISH JOURNAL OF HAEMATOLOGY
- Core Transcriptional Regulatory Circuit Controlled by the TAL1 Complex in Human T Cell Acute Lymphoblastic Leukemia
- (2012) Takaomi Sanda et al. CANCER CELL
- Developmental roles of tribbles protein family members
- (2012) Leonard L. Dobens et al. DEVELOPMENTAL DYNAMICS
- The Mammalian Tribbles Homolog TRIB3, Glucose Homeostasis, and Cardiovascular Diseases
- (2012) Sabrina Prudente et al. ENDOCRINE REVIEWS
- Positive natural selection of TRIB2, a novel gene that influences visceral fat accumulation, in East Asia
- (2012) Kazuhiro Nakayama et al. HUMAN GENETICS
- Tribbles 2 (Trib2) is a novel regulator of toll-like receptor 5 signaling
- (2012) Shu-Chen Wei et al. INFLAMMATORY BOWEL DISEASES
- miR-511 and miR-1297 Inhibit Human Lung Adenocarcinoma Cell Proliferation by Targeting Oncogene TRIB2
- (2012) Chao Zhang et al. PLoS One
- Regulation of TRIB3 mRNA and Protein in Breast Cancer
- (2012) Marloes Wennemers et al. PLoS One
- Tribbles in disease: Signaling pathways important for cellular function and neoplastic transformation
- (2011) Takashi Yokoyama et al. CANCER SCIENCE
- FOG-1 and GATA-1 act sequentially to specify definitive megakaryocytic and erythroid progenitors
- (2011) Elena Mancini et al. EMBO JOURNAL
- Small-molecule hydrophobic tagging–induced degradation of HaloTag fusion proteins
- (2011) Taavi K Neklesa et al. Nature Chemical Biology
- Overexpression of TRIB2 in human lung cancers contributes to tumorigenesis through downregulation of C/EBPα
- (2011) K B Grandinetti et al. ONCOGENE
- Trib1 links the MEK1/ERK pathway in myeloid leukemogenesis
- (2010) T. Yokoyama et al. BLOOD
- Differential ability of Tribbles family members to promote degradation of C/EBP and induce acute myelogenous leukemia
- (2010) P. H. Dedhia et al. BLOOD
- Transformation by Tribbles homolog 2 (Trib2) requires both the Trib2 kinase domain and COP1 binding
- (2010) K. Keeshan et al. BLOOD
- MicroRNA-155Regulates Cell Survival, Growth, and Chemosensitivity by TargetingFOXO3ain Breast Cancer
- (2010) William Kong et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- siRNA Nanoparticle Functionalization of Nanostructured Scaffolds Enables Controlled Multilineage Differentiation of Stem Cells
- (2010) Morten Ø Andersen et al. MOLECULAR THERAPY
- Human TRIB2 is a repressor of FOXO that contributes to the malignant phenotype of melanoma cells
- (2010) F Zanella et al. ONCOGENE
- Abnormal expression of TRIB3 in colorectal cancer: a novel marker for prognosis
- (2009) N Miyoshi et al. BRITISH JOURNAL OF CANCER
- Tribbles-1 and -2 are tumour suppressors, down-regulated in human acute myeloid leukaemia
- (2009) Daniel C. Gilby et al. IMMUNOLOGY LETTERS
- Trb2, a mouse homolog of tribbles, is dispensable for kidney and mouse development
- (2008) Minoru Takasato et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Human tribbles homologue 2 is expressed in unstable regions of carotid plaques and regulates macrophage IL-10in vitro
- (2008) Jingti Deng et al. CLINICAL SCIENCE
- Linkage of Meis1 leukemogenic activity to multiple downstream effectors including Trib2 and Ccl3
- (2008) Bob Argiropoulos et al. EXPERIMENTAL HEMATOLOGY
- Tribbles-2 is a novel regulator of inflammatory activation of monocytes
- (2008) K. Eder et al. INTERNATIONAL IMMUNOLOGY
- Tribbles homolog 2 (Trib2) and HoxA9 cooperate to accelerate acute myelogenous leukemia
- (2007) Karen Keeshan et al. BLOOD CELLS MOLECULES AND DISEASES
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started