Small-molecule hydrophobic tagging–induced degradation of HaloTag fusion proteins

Making It Easier to Regulate Protein Stability

(2010) Erin K. Schrader et al.   CHEMISTRY & BIOLOGY

Targeting the Undruggable Proteome: The Small Molecules of My Dreams

(2010) Craig M. Crews   CHEMISTRY & BIOLOGY

A General Chemical Method to Regulate Protein Stability in the Mammalian Central Nervous System

(2010) Mari Iwamoto et al.   CHEMISTRY & BIOLOGY

Rapid Inactivation of Proteins by Rapamycin-Induced Rerouting to Mitochondria

(2010) Margaret S. Robinson et al.   DEVELOPMENTAL CELL

Genome-wide RNAi screen identifies human host factors crucial for influenza virus replication

(2010) Alexander Karlas et al.   NATURE

Niclosamide Prevents the Formation of Large Ubiquitin-Containing Aggregates Caused by Proteasome Inhibition

(2010) Esther Gies et al.   PLoS One

A Plant-Like Kinase in Plasmodium falciparum Regulates Parasite Egress from Erythrocytes

(2010) J. D. Dvorin et al.   SCIENCE

A Genome-wide RNAi Screen Identifies Multiple Synthetic Lethal Interactions with the Ras Oncogene

(2009) Ji Luo et al.   CELL

Identifying druggable disease-modifying gene products

(2009) Scott J Dixon et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Quality Control Against Misfolded Proteins in the Cytosol: A Network for Cell Survival

(2009) H. Kubota   JOURNAL OF BIOCHEMISTRY

An auxin-based degron system for the rapid depletion of proteins in nonplant cells

(2009) Kohei Nishimura et al.   NATURE METHODS

Knocking down barriers: advances in siRNA delivery

(2009) Kathryn A. Whitehead et al.   NATURE REVIEWS DRUG DISCOVERY

Attenuation of Zinc Finger Nuclease Toxicity by Small-Molecule Regulation of Protein Levels

(2009) Shondra M. Pruett-Miller et al.   PLoS Genetics

HaloTag: A Novel Protein Labeling Technology for Cell Imaging and Protein Analysis

(2008) Georgyi V. Los et al.   ACS Chemical Biology

RNA interference screen for human genes associated with West Nile virus infection

(2008) Manoj N. Krishnan et al.   NATURE

Chemical control of protein stability and function in living mice

(2008) Laura A Banaszynski et al.   NATURE MEDICINE