Developmental roles of tribbles protein family members

The tribbles gene family and lipoprotein metabolism

(2012) Adrienn Angyal et al.   CURRENT OPINION IN LIPIDOLOGY

The Mammalian Tribbles Homolog TRIB3, Glucose Homeostasis, and Cardiovascular Diseases

(2012) Sabrina Prudente et al.   ENDOCRINE REVIEWS

Tribbles: ‘puzzling’ regulators of cell signalling

(2011) Endre Kiss-Toth   BIOCHEMICAL SOCIETY TRANSACTIONS

Tribbles in disease: Signaling pathways important for cellular function and neoplastic transformation

(2011) Takashi Yokoyama et al.   CANCER SCIENCE

Anti-tumoral action of cannabinoids on hepatocellular carcinoma: role of AMPK-dependent activation of autophagy

(2011) D Vara et al.   CELL DEATH AND DIFFERENTIATION

APPL1 Counteracts Obesity-Induced Vascular Insulin Resistance and Endothelial Dysfunction by Modulating the Endothelial Production of Nitric Oxide and Endothelin-1 in Mice

(2011) Yi Wang et al.   DIABETES

TRB3 interacts with SMAD3 promoting tumor cell migration and invasion

(2011) F. Hua et al.   JOURNAL OF CELL SCIENCE

Tetradecylthioacetic acid inhibits proliferation of human SW620 colon cancer cells - gene expression profiling implies endoplasmic reticulum stress

(2011) Anne G Lundemo et al.   Lipids in Health and Disease

Overexpression of TRIB2 in human lung cancers contributes to tumorigenesis through downregulation of C/EBPα

(2011) K B Grandinetti et al.   ONCOGENE

TRIB3 protein denotes a good prognosis in breast cancer patients and is associated with hypoxia sensitivity

(2011) Marloes Wennemers et al.   RADIOTHERAPY AND ONCOLOGY

Trib1 links the MEK1/ERK pathway in myeloid leukemogenesis

(2010) T. Yokoyama et al.   BLOOD

Differential ability of Tribbles family members to promote degradation of C/EBP  and induce acute myelogenous leukemia

(2010) P. H. Dedhia et al.   BLOOD

Transformation by Tribbles homolog 2 (Trib2) requires both the Trib2 kinase domain and COP1 binding

(2010) K. Keeshan et al.   BLOOD

The TRIB3 R84 variant is associated with increased carotid intima–media thickness in vivo and with enhanced MAPK signalling in human endothelial cells

(2010) Gloria Formoso et al.   CARDIOVASCULAR RESEARCH

Control of Adipose Tissue Inflammation Through TRB1

(2010) Anke Ostertag et al.   DIABETES

Human Tribbles homolog 1 functions as a negative regulator of retinoic acid receptor

(2010) Masamichi Imajo et al.   GENES TO CELLS

Mixed Lineage Kinase-3 Stabilizes and Functionally Cooperates with TRIBBLES-3 to Compromise Mitochondrial Integrity in Cytokine-induced Death of Pancreatic Beta Cells

(2010) Rohan K. Humphrey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The pseudokinase tribbles homolog 3 interacts with ATF4 to negatively regulate insulin exocytosis in human and mouse β cells

(2010) Chong Wee Liew et al.   JOURNAL OF CLINICAL INVESTIGATION

Percentage of smudge cells determined on routine blood smears is a novel prognostic factor in chronic lymphocytic leukemia

(2010) P. Johansson et al.   LEUKEMIA RESEARCH

Human TRIB2 is a repressor of FOXO that contributes to the malignant phenotype of melanoma cells

(2010) F Zanella et al.   ONCOGENE

The emerging role of TRIB3 as a gene affecting human insulin resistance and related clinical outcomes

(2009) Sabrina Prudente et al.   ACTA DIABETOLOGICA

Mammalian Tribbles homolog 3 impairs insulin action in skeletal muscle: role in glucose-induced insulin resistance

(2009) Jiarong Liu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Increased expression of the Akt/PKB inhibitor TRB3 in osteoarthritic chondrocytes inhibits insulin-like growth factor 1-mediated cell survival and proteoglycan synthesis

(2009) John D. Cravero et al.   ARTHRITIS AND RHEUMATISM

Abnormal expression of TRIB3 in colorectal cancer: a novel marker for prognosis

(2009) N Miyoshi et al.   BRITISH JOURNAL OF CANCER

Molecular basis for antagonism between PDGF and the TGFβ family of signalling pathways by control of miR-24 expression

(2009) Mun Chun Chan et al.   EMBO JOURNAL

TRB3, upregulated by ox-LDL, mediates human monocyte-derived macrophage apoptosis

(2009) Yuan-yuan Shang et al.   FEBS Journal

Human TRB3 is upregulated in stressed cells by the induction of translationally efficient mRNA containing a truncated 5′-UTR

(2009) Tiit Örd et al.   GENE

Tribbles-1 and -2 are tumour suppressors, down-regulated in human acute myeloid leukaemia

(2009) Daniel C. Gilby et al.   IMMUNOLOGY LETTERS

Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells

(2009) María Salazar et al.   JOURNAL OF CLINICAL INVESTIGATION

Antitumor Effects of Dehydroxymethylepoxyquinomicin, a Novel Nuclear Factor- B Inhibitor, in Human Liver Cancer Cells Are Mediated through a Reactive Oxygen Species-Dependent Mechanism

(2009) N. Lampiasi et al.   MOLECULAR PHARMACOLOGY

Trb2, a mouse homolog of tribbles, is dispensable for kidney and mouse development

(2008) Minoru Takasato et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

EPO receptor circuits for primary erythroblast survival

(2008) P. Sathyanarayana et al.   BLOOD

The Molecular Mechanism of Endoplasmic Reticulum Stress-Induced Apoptosis in PC-12 Neuronal Cells: The Protective Effect of Insulin-Like Growth Factor I

(2008) Cheng-Gang Zou et al.   ENDOCRINOLOGY

Genetic Dissociation of Ethanol Sensitivity and Memory Formation in Drosophila melanogaster

(2008) H. LaFerriere et al.   GENETICS

LDL uptake by monocytes in response to inflammation is MAPK dependent but independent of tribbles protein expression

(2008) Katalin Eder et al.   IMMUNOLOGY LETTERS

TRB3 suppresses adipocyte differentiation by negatively regulating PPARγ transcriptional activity

(2008) Yu Takahashi et al.   JOURNAL OF LIPID RESEARCH

PhosphoPep—a database of protein phosphorylation sites in model organisms

(2008) Bernd Bodenmiller et al.   NATURE BIOTECHNOLOGY

Tribbles homolog 2 (Trib2) and HoxA9 cooperate to accelerate acute myelogenous leukemia

(2007) Karen Keeshan et al.   BLOOD CELLS MOLECULES AND DISEASES