Competition between members of the tribbles pseudokinase protein family shapes their interactions with mitogen activated protein kinase pathways

Multi-Compartmentalisation in the MAPK Signalling Pathway Contributes to the Emergence of Oscillatory Behaviour and to Ultrasensitivity

(2016) Aban Shuaib et al.   PLoS One

Structural Basis for Substrate Selectivity of the E3 Ligase COP1

(2016) Sacha Uljon et al.   STRUCTURE

The Tribbles 2 (TRB2) pseudokinase binds to ATP and autophosphorylates in a metal-independent manner

(2015) Fiona P. Bailey et al.   BIOCHEMICAL JOURNAL

Tribbles in normal and malignant haematopoiesis

(2015) S. J. Stein et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Tribbles breaking bad: TRIB2 suppresses FOXO and acts as an oncogenic protein in melanoma

(2015) W. Link   BIOCHEMICAL SOCIETY TRANSACTIONS

Tribbles in inflammation

(2015) J. Johnston et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Molecular Mechanism of CCAAT-Enhancer Binding Protein Recruitment by the TRIB1 Pseudokinase

(2015) James M. Murphy et al.   STRUCTURE

TRB3 links insulin/IGF to tumour promotion by interacting with p62 and impeding autophagic/proteasomal degradations

(2015) Fang Hua et al.   Nature Communications

Loss of Tribbles pseudokinase-3 promotes Akt-driven tumorigenesis via FOXO inactivation

(2014) M Salazar et al.   CELL DEATH AND DIFFERENTIATION

TRIB2 inhibits Wnt/β-Catenin/TCF4 signaling through its associated ubiquitin E3 ligases, β-TrCP, COP1 and Smurf1, in liver cancer cells

(2014) Shanshan Xu et al.   FEBS LETTERS

The functionally diverse roles of tribbles

(2013) Fiona Lohan et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Tribbles in acute leukemia

(2013) K. L. Liang et al.   BLOOD

Identification of TRIB1 R107L gain-of-function mutation in human acute megakaryocytic leukemia

(2012) T. Yokoyama et al.   BLOOD

The Tribbles-1 Protein in Humans: Roles and Functions in Health and Disease

(2012) E. Dugast et al.   CURRENT MOLECULAR MEDICINE

The tribbles gene family and lipoprotein metabolism

(2012) Adrienn Angyal et al.   CURRENT OPINION IN LIPIDOLOGY

Tribbles 2 (Trib2) is a novel regulator of toll-like receptor 5 signaling

(2012) Shu-Chen Wei et al.   INFLAMMATORY BOWEL DISEASES

Tribbles: ‘puzzling’ regulators of cell signalling

(2011) Endre Kiss-Toth   BIOCHEMICAL SOCIETY TRANSACTIONS

Anaphase-promoting complex/cyclosome-cdh1 mediates the ubiquitination and degradation of TRB3

(2010) Nobumichi Ohoka et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Trib1 links the MEK1/ERK pathway in myeloid leukemogenesis

(2010) T. Yokoyama et al.   BLOOD

Differential ability of Tribbles family members to promote degradation of C/EBP  and induce acute myelogenous leukemia

(2010) P. H. Dedhia et al.   BLOOD

Tribbles-1 and -2 are tumour suppressors, down-regulated in human acute myeloid leukaemia

(2009) Daniel C. Gilby et al.   IMMUNOLOGY LETTERS

E3 ubiquitin ligase SIAH1 mediates ubiquitination and degradation of TRB3

(2008) Ying Zhou et al.   CELLULAR SIGNALLING

Tribbles-2 is a novel regulator of inflammatory activation of monocytes

(2008) K. Eder et al.   INTERNATIONAL IMMUNOLOGY

Tribbles-1 as a Novel Biomarker of Chronic Antibody-Mediated Rejection

(2008) J. Ashton-Chess et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY