Lactate as Potential Mediators for Exercise-Induced Positive Effects on Neuroplasticity and Cerebrovascular Plasticity
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Lactate as Potential Mediators for Exercise-Induced Positive Effects on Neuroplasticity and Cerebrovascular Plasticity
Authors
Keywords
-
Journal
Frontiers in Physiology
Volume 12, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2021-07-05
DOI
10.3389/fphys.2021.656455
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Cerebral Hemodynamic and Neurotrophic Factor Responses Are Dependent on the Type of Exercise
- (2021) Samuel R. Weaver et al. Frontiers in Physiology
- Elevated Lactate by High-Intensity Interval Training Regulates the Hippocampal BDNF Expression and the Mitochondrial Quality Control System
- (2021) Jingyun Hu et al. Frontiers in Physiology
- Effects of Exercise Training on Anxious–Depressive-like Behavior in Alzheimer Rat
- (2020) Chongyun Wu et al. MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
- Effects of high-intensity interval training on adipose tissue lipolysis, inflammation, and metabolomics in aged rats
- (2020) Lei Sun et al. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- Acute Sprint Interval Exercise Increases Both Cognitive Functions and Peripheral Neurotrophic Factors in Humans: The Possible Involvement of Lactate
- (2020) Sylwester Kujach et al. Frontiers in Neuroscience
- Exercise training ameliorates cerebrovascular dysfunction in a murine model of Alzheimer's Disease: Role of the P2Y2 receptor and endoplasmic reticulum stress
- (2020) Junyoung Hong et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Physical exercise promotes astrocyte coverage of microvessels in a model of chronic cerebral hypoperfusion
- (2020) Marina Leardini-Tristão et al. Journal of Neuroinflammation
- Aerobic exercise improves cognition and cerebrovascular regulation in older adults
- (2020) Veronica Guadagni et al. NEUROLOGY
- Effects of Exercise on Brain and Cognition Across Age Groups and Health States
- (2020) Chelsea M. Stillman et al. TRENDS IN NEUROSCIENCES
- Lactate and BDNF: Key Mediators of Exercise Induced Neuroplasticity?
- (2020) Patrick Müller et al. Journal of Clinical Medicine
- One-Week High-Intensity Interval Training Increases Hippocampal Plasticity and Mitochondrial Content without Changes in Redox State
- (2020) Jonathas Rodrigo dos Santos et al. Antioxidants
- A Unique Mouse Model of Early Life Exercise Enables Hippocampal Memory and Synaptic Plasticity
- (2020) Autumn S. Ivy et al. Scientific Reports
- Effect of exercise training for five years on all cause mortality in older adults—the Generation 100 study: randomised controlled trial
- (2020) Dorthe Stensvold et al. BMJ-British Medical Journal
- Introduction to special topic on exercise and oxidative stress
- (2020) Zsolt Radak et al. Journal of Sport and Health Science
- L ‐lactate induces neurogenesis in the mouse ventricular‐subventricular zone via the lactate receptor HCA 1
- (2020) Marvin Lambertus et al. Acta Physiologica
- Lactate is an antidepressant that mediates resilience to stress by modulating the hippocampal levels and activity of histone deacetylases
- (2019) Nabil Karnib et al. NEUROPSYCHOPHARMACOLOGY
- A role for FNDC5/Irisin in the beneficial effects of exercise on the brain and in neurodegenerative diseases
- (2019) Michael F. Young et al. PROGRESS IN CARDIOVASCULAR DISEASES
- Adult hippocampal neurogenesis is abundant in neurologically healthy subjects and drops sharply in patients with Alzheimer’s disease
- (2019) Elena P. Moreno-Jiménez et al. NATURE MEDICINE
- The beneficial effects of physical exercise in the brain and related pathophysiological mechanisms in neurodegenerative diseases
- (2019) Yan Liu et al. LABORATORY INVESTIGATION
- Lactate mediates the effects of exercise on learning and memory through SIRT1-dependent activation of hippocampal brain-derived neurotrophic factor (BDNF)
- (2019) Lauretta El Hayek et al. JOURNAL OF NEUROSCIENCE
- Blood-brain barrier permeability and physical exercise
- (2019) Marta A. Małkiewicz et al. Journal of Neuroinflammation
- The effect of exercise on memory and BDNF signaling is dependent on intensity
- (2019) Marina Cefis et al. Brain Structure & Function
- Intensity Matters: High-intensity Interval Exercise Enhances Motor Cortex Plasticity More Than Moderate Exercise
- (2019) Sophie C Andrews et al. CEREBRAL CORTEX
- The lactate receptor HCAR1 modulates neuronal network activity through the activation of Gα and Gβɣ subunits
- (2019) Haíssa de Castro Abrantes et al. JOURNAL OF NEUROSCIENCE
- L-Lactate Promotes Adult Hippocampal Neurogenesis
- (2019) Yaeli Lev-Vachnish et al. Frontiers in Neuroscience
- Cerebrovascular plasticity: Processes that lead to changes in the architecture of brain microvessels
- (2019) Max I Bogorad et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Mimicking exercise: What matters most and where to next?
- (2019) John A. Hawley et al. JOURNAL OF PHYSIOLOGY-LONDON
- Early exercise induces long-lasting morphological changes in cortical and hippocampal neurons throughout of a sedentary period of rats
- (2019) Fernando Tadeu Serra et al. Scientific Reports
- Differential effects of L- and D-lactate on memory encoding and consolidation: Potential role of HCAR1 signaling
- (2019) Claire J. Scavuzzo et al. NEUROBIOLOGY OF LEARNING AND MEMORY
- Aerobic Exercise Training Improves Cerebral Blood Flow and Executive Function: A Randomized, Controlled Cross-Over Trial in Sedentary Older Men
- (2019) Jordi P. D. Kleinloog et al. Frontiers in Aging Neuroscience
- Lactate metabolism: historical context, prior misinterpretations, and current understanding
- (2018) Brian S. Ferguson et al. EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY
- Swimming exercise reverses CUMS-induced changes in depression-like behaviors and hippocampal plasticity-related proteins
- (2018) Weina Liu et al. JOURNAL OF AFFECTIVE DISORDERS
- Beneficial Effects of Exercise Pretreatment in a Sporadic Alzheimer’s Rat Model
- (2018) CHONGYUN WU et al. MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
- Lactate in the brain: from metabolic end-product to signalling molecule
- (2018) Pierre J. Magistretti et al. NATURE REVIEWS NEUROSCIENCE
- Exercise-induced neuroplasticity: Balance training increases cortical thickness in visual and vestibular cortical regions
- (2018) Ann-Kathrin Rogge et al. NEUROIMAGE
- Effects of different endurance exercise modalities on migraine days and cerebrovascular health in episodic migraineurs: A randomized controlled trial
- (2018) H. Hanssen et al. SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS
- Cerebral Blood Flow Measurements in Adults: A Review on the Effects of Dietary Factors and Exercise
- (2018) Peter Joris et al. Nutrients
- The role of brain vasculature in neurodegenerative disorders
- (2018) Melanie D. Sweeney et al. NATURE NEUROSCIENCE
- Combined adult neurogenesis and BDNF mimic exercise effects on cognition in an Alzheimer’s mouse model
- (2018) Se Hoon Choi et al. SCIENCE
- The effect of physical exercise on cerebral blood flow in Alzheimer's disease
- (2018) Lisa A. van der Kleij et al. NeuroImage-Clinical
- Acute high-intensity interval exercise induces greater levels of serum brain-derived neurotrophic factor in obese individuals
- (2018) Alexandra L Rodriguez et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- Exercise-linked FNDC5/irisin rescues synaptic plasticity and memory defects in Alzheimer’s models
- (2018) Mychael V. Lourenco et al. NATURE MEDICINE
- The Volume of Hippocampal Subfields in Relation to Decline of Memory Recall Across the Adult Lifespan
- (2018) Fenglian Zheng et al. Frontiers in Aging Neuroscience
- The Impact of High-Intensity Interval Training on Brain Derived Neurotrophic Factor in Brain: A Mini-Review
- (2018) Alberto Jiménez-Maldonado et al. Frontiers in Neuroscience
- Treadmill exercise ameliorates focal cerebral ischemia/reperfusion-induced neurological deficit by promoting dendritic modification and synaptic plasticity via upregulating caveolin-1/VEGF signaling pathways
- (2018) Qingfeng Xie et al. EXPERIMENTAL NEUROLOGY
- The role of exercise in mitigating subcortical ischemic vascular cognitive impairment
- (2017) Elizabeth Dao et al. JOURNAL OF NEUROCHEMISTRY
- The novel exercise-induced hormone irisin protects against neuronal injury via activation of the Akt and ERK1/2 signaling pathways and contributes to the neuroprotection of physical exercise in cerebral ischemia
- (2017) Dong-Jie Li et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Physiology and role of irisin in glucose homeostasis
- (2017) Nikolaos Perakakis et al. Nature Reviews Endocrinology
- Cerebral blood flow regulation and neurovascular dysfunction in Alzheimer disease
- (2017) Kassandra Kisler et al. NATURE REVIEWS NEUROSCIENCE
- The blood-brain barrier in Alzheimer's disease
- (2017) Elena Zenaro et al. NEUROBIOLOGY OF DISEASE
- Physical exercise as an epigenetic modulator of brain plasticity and cognition
- (2017) Jansen Fernandes et al. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
- Astrocytic glycogen-derived lactate fuels the brain during exhaustive exercise to maintain endurance capacity
- (2017) Takashi Matsui et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Exercise induces cerebral VEGF and angiogenesis via the lactate receptor HCAR1
- (2017) Cecilie Morland et al. Nature Communications
- In Vivo Evidence for a Lactate Gradient from Astrocytes to Neurons
- (2016) Philipp Mächler et al. Cell Metabolism
- Lactate as a Metabolite and a Regulator in the Central Nervous System
- (2016) Patrizia Proia et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- High-intensity treadmill running impairs cognitive behavior and hippocampal synaptic plasticity of rats via activation of inflammatory response
- (2016) Li-na Sun et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Exercise-induced oxidative stress: past, present and future
- (2016) Scott K. Powers et al. JOURNAL OF PHYSIOLOGY-LONDON
- Relation of cerebral vessel disease to Alzheimer's disease dementia and cognitive function in elderly people: a cross-sectional study
- (2016) Zoe Arvanitakis et al. LANCET NEUROLOGY
- Peripheral administration of lactate produces antidepressant-like effects
- (2016) A Carrard et al. MOLECULAR PSYCHIATRY
- Neuroinflammation negatively affects adult hippocampal neurogenesis and cognition: can exercise compensate?
- (2016) Sinéad M. Ryan et al. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
- Lactate: Friend or Foe
- (2016) Mederic M. Hall et al. PM&R
- FNDC5 expression and circulating irisin levels are modified by diet and hormonal conditions in hypothalamus, adipose tissue and muscle
- (2016) B. M. Varela-Rodríguez et al. Scientific Reports
- Neuronal and Vascular Interactions
- (2015) Benjamin J. Andreone et al. Annual Review of Neuroscience
- Establishment and Dysfunction of the Blood-Brain Barrier
- (2015) Zhen Zhao et al. CELL
- Fndc5overexpression facilitated neural differentiation of mouse embryonic stem cells
- (2015) Mahboobeh Forouzanfar et al. CELL BIOLOGY INTERNATIONAL
- Physical exercise, neuroplasticity, spatial learning and memory
- (2015) Ricardo C. Cassilhas et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Enhanced expression of FNDC5 in human embryonic stem cell-derived neural cells along with relevant embryonic neural tissues
- (2015) Fatemeh Ahmadi Ghahrizjani et al. GENE
- High-intensity interval training evokes larger serum BDNF levels compared with intense continuous exercise
- (2015) Cinthia Maria Saucedo Marquez et al. JOURNAL OF APPLIED PHYSIOLOGY
- High-Intensity Interval Exercise and Cerebrovascular Health: Curiosity, Cause, and Consequence
- (2015) Samuel JE Lucas et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Neurogenesis and vascularization of the damaged brain using a lactate-releasing biomimetic scaffold
- (2014) Zaida Álvarez et al. BIOMATERIALS
- Neuronal Plasticity: Beyond the Critical Period
- (2014) Mark Hübener et al. CELL
- Irisin and FGF21 Are Cold-Induced Endocrine Activators of Brown Fat Function in Humans
- (2014) Paul Lee et al. Cell Metabolism
- Cerebral metabolic effects of exogenous lactate supplementation on the injured human brain
- (2014) Pierre Bouzat et al. INTENSIVE CARE MEDICINE
- Irisin stimulates muscle growth-related genes and regulates adipocyte differentiation and metabolism in humans
- (2014) J Y Huh et al. INTERNATIONAL JOURNAL OF OBESITY
- Acute exercise increases brain region-specific expression of MCT1, MCT2, MCT4, GLUT1, and COX IV proteins
- (2014) Masaki Takimoto et al. JOURNAL OF APPLIED PHYSIOLOGY
- Lactate Transport and Signaling in the Brain: Potential Therapeutic Targets and Roles in Body—Brain Interaction
- (2014) Linda Hildegard Bergersen JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Effect of high-intensity exercise on aged mouse brain mitochondria, neurogenesis, and inflammation
- (2014) Lezi E et al. NEUROBIOLOGY OF AGING
- Cerebrovascular regulation, exercise, and mild traumatic brain injury
- (2014) C. O. Tan et al. NEUROLOGY
- Effects of High Intensity Training and High Volume Training on Endothelial Microparticles and Angiogenic Growth Factors
- (2014) Patrick Wahl et al. PLoS One
- Lactate promotes plasticity gene expression by potentiating NMDA signaling in neurons
- (2014) J. Yang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Exercise Induces Hippocampal BDNF through a PGC-1α/FNDC5 Pathway
- (2013) Christiane D. Wrann et al. Cell Metabolism
- Exercise Therapy Augments the Ischemia-Induced Proangiogenic State and Results in Sustained Improvement after Stroke
- (2013) Yuewen Ma et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Lactate administration reproduces specific brain and liver exercise-related changes
- (2013) Lezi E et al. JOURNAL OF NEUROCHEMISTRY
- Early exercise improves cerebral blood flow through increased angiogenesis in experimental stroke rat model
- (2013) Pengyue Zhang et al. Journal of NeuroEngineering and Rehabilitation
- The Pathobiology of Vascular Dementia
- (2013) Costantino Iadecola NEURON
- Irisin-immunoreactivity in neural and non-neural cells of the rodent
- (2013) S.L. Dun et al. NEUROSCIENCE
- Life-span plasticity of the brain and cognition: From questions to evidence and back
- (2013) Naftali Raz et al. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
- Beneficial effects of physical exercise on neuroplasticity and cognition
- (2013) Kirsten Hötting et al. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
- New Evidence of Neuroprotection by Lactate after Transient Focal Cerebral Ischaemia: Extended Benefit after Intracerebroventricular Injection and Efficacy of Intravenous Administration
- (2012) Carole Berthet et al. CEREBROVASCULAR DISEASES
- The pandemic of physical inactivity: global action for public health
- (2012) Harold W Kohl et al. LANCET
- Effect of physical inactivity on major non-communicable diseases worldwide: an analysis of burden of disease and life expectancy
- (2012) I-Min Lee et al. LANCET
- A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis
- (2012) Pontus Boström et al. NATURE
- Acute moderate exercise enhances compensatory brain activation in older adults
- (2012) Kazuki Hyodo et al. NEUROBIOLOGY OF AGING
- Mild exercise increases dihydrotestosterone in hippocampus providing evidence for androgenic mediation of neurogenesis
- (2012) M. Okamoto et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Astrocyte-Neuron Lactate Transport Is Required for Long-Term Memory Formation
- (2011) Akinobu Suzuki et al. CELL
- Brain glycogen decreases during prolonged exercise
- (2011) T. Matsui et al. JOURNAL OF PHYSIOLOGY-LONDON
- Brain-derived neurotrophic factor enhances the hippocampal expression of key postsynaptic proteins in vivo including the monocarboxylate transporter MCT2
- (2011) C. Robinet et al. NEUROSCIENCE
- Exercise training increases size of hippocampus and improves memory
- (2011) K. I. Erickson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Lactate infusion at rest increases BDNF blood concentration in humans
- (2010) Thorsten Schiffer et al. NEUROSCIENCE LETTERS
- Neuroplasticity – Exercise-Induced Response of Peripheral Brain-Derived Neurotrophic Factor
- (2010) Kristel Knaepen et al. SPORTS MEDICINE
- The human brain utilizes lactate via the tricarboxylic acid cycle: a 13C-labelled microdialysis and high-resolution nuclear magnetic resonance study
- (2009) Clare N. Gallagher et al. BRAIN
- Exercise-induced improvement in cognitive performance after traumatic brain injury in rats is dependent on BDNF activation
- (2009) Grace Sophia Griesbach et al. BRAIN RESEARCH
- Neuroprotective Role of Lactate after Cerebral Ischemia
- (2009) Carole Berthet et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Brain-Derived Neurotrophic Factor Enhances the Expression of the Monocarboxylate Transporter 2 through Translational Activation in Mouse Cultured Cortical Neurons
- (2009) Camille Robinet et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Lactate fuels the human brain during exercise
- (2008) Bjørn Quistorff et al. FASEB JOURNAL
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started