L ‐lactate induces neurogenesis in the mouse ventricular‐subventricular zone via the lactate receptor HCA 1

Brain energy rescue: an emerging therapeutic concept for neurodegenerative disorders of ageing

(2020) Stephen C. Cunnane et al.   NATURE REVIEWS DRUG DISCOVERY

Lactate enhances Arc/arg3.1 expression through hydroxycarboxylic acid receptor 1-β-arrestin2 pathway in astrocytes

(2020) Kaiyang Ma et al.   NEUROPHARMACOLOGY

The Lactate Receptor HCA1 Is Present in the Choroid Plexus, the Tela Choroidea, and the Neuroepithelial Lining of the Dorsal Part of the Third Ventricle

(2020) Alena Hadzic et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Adult hippocampal neurogenesis is abundant in neurologically healthy subjects and drops sharply in patients with Alzheimer’s disease

(2019) Elena P. Moreno-Jiménez et al.   NATURE MEDICINE

The lactate receptor HCAR1 modulates neuronal network activity through the activation of Gα and Gβɣ subunits

(2019) Haíssa de Castro Abrantes et al.   JOURNAL OF NEUROSCIENCE

Exercise and Hippocampal Memory Systems

(2019) Michelle W. Voss et al.   TRENDS IN COGNITIVE SCIENCES

L-Lactate Promotes Adult Hippocampal Neurogenesis

(2019) Yaeli Lev-Vachnish et al.   Frontiers in Neuroscience

Adult neurogenesis in mammals

(2019) Fred H. Gage   SCIENCE

Good publication practice in physiology 2019

(2019) Pontus B. Persson   Acta Physiologica

Differential effects of L- and D-lactate on memory encoding and consolidation: Potential role of HCAR1 signaling

(2019) Claire J. Scavuzzo et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Lactate enhanced the effect of parathyroid hormone on osteoblast differentiation via GPR81-PKC-Akt signaling

(2018) Yu Wu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Human Hippocampal Neurogenesis Persists throughout Aging

(2018) Maura Boldrini et al.   Cell Stem Cell

Human Adult Neurogenesis: Evidence and Remaining Questions

(2018) Gerd Kempermann et al.   Cell Stem Cell

Human hippocampal neurogenesis drops sharply in children to undetectable levels in adults

(2018) Shawn F. Sorrells et al.   NATURE

Intermittent metabolic switching, neuroplasticity and brain health

(2018) Mark P. Mattson et al.   NATURE REVIEWS NEUROSCIENCE

Exercise-Induced Neuroplasticity: A Mechanistic Model and Prospects for Promoting Plasticity

(2018) Jenin El-Sayes et al.   NEUROSCIENTIST

Exercise-Mediated Neurogenesis in the Hippocampus via BDNF

(2018) Patrick Z. Liu et al.   Frontiers in Neuroscience

Depression and adult neurogenesis: positive effects of the antidepressant fluoxetine and of physical exercise

(2018) Laura Micheli et al.   BRAIN RESEARCH BULLETIN

Does Adult Neurogenesis Persist in the Human Hippocampus?

(2018) Mercedes F. Paredes et al.   Cell Stem Cell

Exercise-linked FNDC5/irisin rescues synaptic plasticity and memory defects in Alzheimer’s models

(2018) Mychael V. Lourenco et al.   NATURE MEDICINE

Exercise effects on depression: Possible neural mechanisms

(2017) Swathi Gujral et al.   GENERAL HOSPITAL PSYCHIATRY

Stromal Cell Niches in the Inflamed Central Nervous System

(2017) Natalia B. Pikor et al.   JOURNAL OF IMMUNOLOGY

Dementia prevention, intervention, and care

(2017) Gill Livingston et al.   LANCET

A new inhibitor of the β-arrestin/AP2 endocytic complex reveals interplay between GPCR internalization and signalling

(2017) Alexandre Beautrait et al.   Nature Communications

Exercise induces cerebral VEGF and angiogenesis via the lactate receptor HCAR1

(2017) Cecilie Morland et al.   Nature Communications

MicroRNA-9 Couples Brain Neurogenesis and Angiogenesis

(2017) Romain Madelaine et al.   Cell Reports

High Plasticity of New Granule Cells in the Aging Hippocampus

(2017) Mariela F. Trinchero et al.   Cell Reports

On the Run for Hippocampal Plasticity

(2017) C’iana Cooper et al.   Cold Spring Harbor Perspectives in Medicine

Running reorganizes the circuitry of one-week-old adult-born hippocampal neurons

(2017) Nirnath Sah et al.   Scientific Reports

Voluntary Wheel Running Reverses the Decrease in Subventricular Zone Neurogenesis Caused by Corticosterone

(2016) Jada Chia-Di Lee et al.   CELL TRANSPLANTATION

Exercise as a treatment for depression: A meta-analysis

(2016) Siri Kvam et al.   JOURNAL OF AFFECTIVE DISORDERS

Exercise as a treatment for depression: A meta-analysis adjusting for publication bias

(2016) Felipe B. Schuch et al.   JOURNAL OF PSYCHIATRIC RESEARCH

A spectrum of exercise training reduces soluble Aβ in a dose-dependent manner in a mouse model of Alzheimer's disease

(2016) Kaitlin M. Moore et al.   NEUROBIOLOGY OF DISEASE

Exercise for depression in older adults: a meta-analysis of randomized controlled trials adjusting for publication bias

(2016) Felipe B. Schuch et al.   REVISTA BRASILEIRA DE PSIQUIATRIA

G-protein-coupled receptor 81 promotes a malignant phenotype in breast cancer through angiogenic factor secretion

(2016) Yu Jin Lee et al.   Oncotarget

Aerobic interval training reduces inducible ventricular arrhythmias in diabetic mice after myocardial infarction

(2015) Natale Rolim et al.   BASIC RESEARCH IN CARDIOLOGY

Voluntary Running Attenuates Memory Loss, Decreases Neuropathological Changes and Induces Neurogenesis in a Mouse Model of Alzheimer's Disease

(2015) Cheril Tapia-Rojas et al.   BRAIN PATHOLOGY

Classic and novel stem cell niches in brain homeostasis and repair

(2015) Ruihe Lin et al.   BRAIN RESEARCH

Voluntary exercise induces neurogenesis in the hypothalamus and ependymal lining of the third ventricle

(2015) Atsuko Niwa et al.   Brain Structure & Function

Effects of Physical Exercise on Depressive Symptoms and Biomarkers in Depression

(2015) Trevor Archer et al.   CNS & Neurological Disorders-Drug Targets

Protective Effects of Physical Exercise in Alzheimer's Disease and Parkinson's Disease: A Narrative Review

(2015) Thierry Paillard et al.   Journal of Clinical Neurology

The lactate receptor, G-protein-coupled receptor 81/hydroxycarboxylic acid receptor 1: Expression and action in brain

(2015) Cecilie Morland et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Physical Activity Is Positively Associated with Episodic Memory in Aging

(2015) Scott M. Hayes et al.   JOURNAL OF THE INTERNATIONAL NEUROPSYCHOLOGICAL SOCIETY

The vascular niche in adult neurogenesis

(2015) Tamar Licht et al.   MECHANISMS OF DEVELOPMENT

Treadmill Running Reverses Cognitive Declines due to Alzheimer Disease

(2015) JINKYUNG CHO et al.   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

Studying Human Brain Inflammation in Leptomeningeal and Choroid Plexus Explant Cultures

(2015) Mike Dragunow et al.   NEUROCHEMICAL RESEARCH

Increasing Adult Hippocampal Neurogenesis is Sufficient to Reduce Anxiety and Depression-Like Behaviors

(2015) Alexis S Hill et al.   NEUROPSYCHOPHARMACOLOGY

Does physical activity prevent cognitive decline and dementia?: A systematic review and meta-analysis of longitudinal studies

(2014) Sarah J Blondell et al.   BMC PUBLIC HEALTH

Epidemiologic studies of modifiable factors associated with cognition and dementia: systematic review and meta-analysis

(2014) May A Beydoun et al.   BMC PUBLIC HEALTH

Neurogenesis in the Striatum of the Adult Human Brain

(2014) Aurélie Ernst et al.   CELL

Exercise therapy improves both mental and physical health in patients with major depression

(2014) Jan Knapen et al.   DISABILITY AND REHABILITATION

Cardiorespiratory Fitness Is Associated With Cognitive Performance in Older But Not Younger Adults

(2014) Scott M. Hayes et al.   JOURNALS OF GERONTOLOGY SERIES B-PSYCHOLOGICAL SCIENCES AND SOCIAL SCIENCES

Physical activity attenuates age-related biomarker alterations in preclinical AD

(2014) O. C. Okonkwo et al.   NEUROLOGY

Vascular and Neurogenic Rejuvenation of the Aging Mouse Brain by Young Systemic Factors

(2014) L. Katsimpardi et al.   SCIENCE

Tis21 is required for adult neurogenesis in the subventricular zone and for olfactory behavior regulating cyclins, BMP4, Hes1/5 and Ids

(2014) Stefano Farioli-Vecchioli et al.   Frontiers in Cellular Neuroscience

Physical Exercise-Induced Adult Neurogenesis: A Good Strategy to Prevent Cognitive Decline in Neurodegenerative Diseases?

(2014) Suk-yu Yau et al.   Biomed Research International

The MEF2 family and the brain: from molecules to memory

(2013) Jean-Bernard Dietrich   CELL AND TISSUE RESEARCH

Lactate Receptor Sites Link Neurotransmission, Neurovascular Coupling, and Brain Energy Metabolism

(2013) K. H. Lauritzen et al.   CEREBRAL CORTEX

Cell genesis and dendritic plasticity: a neuroplastic pas de deux in the onset and remission from depression

(2013) A Mateus-Pinheiro et al.   MOLECULAR PSYCHIATRY

Lactate Modulates the Activity of Primary Cortical Neurons through a Receptor-Mediated Pathway

(2013) Luigi Bozzo et al.   PLoS One

Spatiotemporal Changes to the Subventricular Zone Stem Cell Pool through Aging

(2012) B. A. Shook et al.   JOURNAL OF NEUROSCIENCE

Oxytocin Promotes Long-Term Potentiation by Enhancing Epidermal Growth Factor Receptor-Mediated Local Translation of Protein Kinase M 

(2012) Y.-T. Lin et al.   JOURNAL OF NEUROSCIENCE

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

GH Mediates Exercise-Dependent Activation of SVZ Neural Precursor Cells in Aged Mice

(2012) Daniel G. Blackmore et al.   PLoS One

Identification of Hydroxybenzoic Acids as Selective Lactate Receptor (GPR81) Agonists with Antilipolytic Effects

(2012) Curt A. Dvorak et al.   ACS Medicinal Chemistry Letters

Astrocyte-Neuron Lactate Transport Is Required for Long-Term Memory Formation

(2011) Akinobu Suzuki et al.   CELL

The ageing systemic milieu negatively regulates neurogenesis and cognitive function

(2011) Saul A. Villeda et al.   NATURE

Treadmill exercise prevents decline in spatial learning and memory in APP/PS1 transgenic mice through improvement of hippocampal long-term potentiation

(2010) Hui-li Liu et al.   BEHAVIOURAL BRAIN RESEARCH

An Autocrine Lactate Loop Mediates Insulin-Dependent Inhibition of Lipolysis through GPR81

(2010) Kashan Ahmed et al.   Cell Metabolism

Adult Hippocampal Neurogenesis: A Possible Way how Physical Exercise Counteracts Stress

(2010) Suk-Yu Yau et al.   CELL TRANSPLANTATION

Exercise increases neural stem cell proliferation surrounding the area of damage following rat traumatic brain injury

(2010) Tatsuki Itoh et al.   JOURNAL OF NEURAL TRANSMISSION

CREB's control of intrinsic and synaptic plasticity: implications for CREB-dependent memory models

(2010) Eva Benito et al.   TRENDS IN NEUROSCIENCES

Olfactory Memory

(2009) Howard Eichenbaum et al.   Annals of the New York Academy of Sciences

Effects of voluntary and forced exercise on plaque deposition, hippocampal volume, and behavior in the Tg2576 mouse model of Alzheimer's disease

(2009) Carla M. Yuede et al.   NEUROBIOLOGY OF DISEASE

Exercise and the brain: something to chew on

(2009) Henriette van Praag   TRENDS IN NEUROSCIENCES

Lactate Inhibits Lipolysis in Fat Cells through Activation of an Orphan G-protein-coupled Receptor, GPR81

(2008) Changlu Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neurogenesis and Exercise: Past and Future Directions

(2008) Henriette van Praag   NEUROMOLECULAR MEDICINE

Growth factors, stem cells, and stroke

(2008) Haviryaji S. G. Kalluri et al.   Neurosurgical Focus

Inhibition of astrocytic energy metabolism by d-lactate exposure impairs memory

(2007) Marie E. Gibbs et al.   NEUROCHEMISTRY INTERNATIONAL