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Title
Role of Lipogenesis Rewiring in Hepatocellular Carcinoma
Authors
Keywords
-
Journal
SEMINARS IN LIVER DISEASE
Volume -, Issue -, Pages -
Publisher
Georg Thieme Verlag KG
Online
2021-07-27
DOI
10.1055/s-0041-1731709
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Note: Only part of the references are listed.- ATP citrate lyase inhibitor triggers endoplasmic reticulum stress to induce hepatocellular carcinoma cell apoptosis via p‐eIF2α/ATF4/CHOP axis
- (2021) Yihu Zheng et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
- (2021) Hyuna Sung et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Lipid metabolism in cancer: New perspectives and emerging mechanisms
- (2021) Lindsay A. Broadfield et al. DEVELOPMENTAL CELL
- NASH and NAFLD: emerging drugs, therapeutic targets and translational and clinical challenges
- (2020) Naim Alkhouri EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Advances in molecular classification and precision oncology in hepatocellular carcinoma
- (2020) Sandra Rebouissou et al. JOURNAL OF HEPATOLOGY
- Stabilization of FASN by ACAT1-mediated GNPAT acetylation promotes lipid metabolism and hepatocarcinogenesis
- (2020) Li Gu et al. ONCOGENE
- Lipid desaturation-associated endoplasmic reticulum stress regulates MYCN gene expression in hepatocellular carcinoma cells
- (2020) Xian-Yang Qin et al. Cell Death & Disease
- The IKKβ-USP30-ACLY Axis Controls Lipogenesis and Tumorigenesis
- (2020) Li Gu et al. HEPATOLOGY
- UBC12‐mediated SREBP‐1 neddylation worsens metastatic tumor prognosis
- (2020) Mi Jeong Heo et al. INTERNATIONAL JOURNAL OF CANCER
- The gluconeogenic enzyme PCK1 phosphorylates INSIG1/2 for lipogenesis
- (2020) Daqian Xu et al. NATURE
- Atezolizumab plus Bevacizumab in Unresectable Hepatocellular Carcinoma
- (2020) Richard S. Finn et al. NEW ENGLAND JOURNAL OF MEDICINE
- Orlistat delays hepatocarcinogenesis in mice with hepatic co-activation of AKT and c-Met
- (2020) Cong Zhang et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- ZHX2 inhibits SREBP1c ‐mediated de novo lipogenesis in hepatocellular carcinoma via miR ‐24‐3p
- (2020) Xiangguo Yu et al. JOURNAL OF PATHOLOGY
- Hydroxycitric acid potentiates the cytotoxic effect of tamoxifen in MCF-7 breast cancer cells through inhibition of ATP citrate lyase
- (2020) Ahmed Ismail et al. STEROIDS
- ATP-citrate lyase regulates stemness and metastasis in hepatocellular carcinoma via the Wnt/β-catenin signaling pathway
- (2020) Qin Han et al. Hepatobiliary & Pancreatic Diseases International
- Liposome-Mediated Inhibition of Inflammation by Hydroxycitrate
- (2020) Antonio Vassallo et al. Nanomaterials
- Immunotherapy for Hepatocellular Carcinoma: A 2021 Update
- (2020) Christo Kole et al. Cancers
- HCAR1/MCT1 Regulates Tumor Ferroptosis through the Lactate-Mediated AMPK-SCD1 Activity and Its Therapeutic Implications
- (2020) Youbo Zhao et al. Cell Reports
- ChREBP-Mediated Regulation of Lipid Metabolism: Involvement of the Gut Microbiota, Liver, and Adipose Tissue
- (2020) Katsumi Iizuka et al. Frontiers in Endocrinology
- The Warburg effect: essential part of metabolic reprogramming and central contributor to cancer progression
- (2019) Peter Vaupel et al. INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
- ETC-1002 (Bempedoic acid) for the management of hyperlipidemia: from preclinical studies to phase 3 trials
- (2019) M. Ruscica et al. EXPERT OPINION ON PHARMACOTHERAPY
- Cholesterol biosynthesis supports the growth of hepatocarcinoma lesions depleted of fatty acid synthase in mice and humans
- (2019) Li Che et al. GUT
- Stearoyl-CoA Desaturase 1 as a Therapeutic Target for the Treatment of Cancer
- (2019) Zuzanna Tracz-Gaszewska et al. Cancers
- FGF19–FGFR4 Signaling in Hepatocellular Carcinoma
- (2019) Aroosha Raja et al. Cells
- SREBP-1 inhibitor Betulin enhances the antitumor effect of Sorafenib on hepatocellular carcinoma via restricting cellular glycolytic activity
- (2019) Fan Yin et al. Cell Death & Disease
- First‐in‐class fatty acid synthase inhibitor TVB‐2640 reduces hepatic de novo lipogenesis in males with metabolic abnormalities
- (2019) Majid M. Syed‐Abdul et al. HEPATOLOGY
- ATP citrate lyase: A central metabolic enzyme in cancer
- (2019) Philippe Icard et al. CANCER LETTERS
- Pathogenetic, Prognostic, and Therapeutic Role of Fatty Acid Synthase in Human Hepatocellular Carcinoma
- (2019) Li Che et al. Frontiers in Oncology
- Chemical genetics in tumor lipogenesis
- (2018) Simone Braig BIOTECHNOLOGY ADVANCES
- EASL Clinical Practice Guidelines: Management of hepatocellular carcinoma
- (2018) Peter R. Galle et al. JOURNAL OF HEPATOLOGY
- Canonical Wnt signaling remodels lipid metabolism in zebrafish hepatocytes following Ras oncogenic insult
- (2018) Yuxiao Yao et al. CANCER RESEARCH
- Bempedoic acid
- (2018) Amy C. Burke et al. CURRENT OPINION IN LIPIDOLOGY
- Fatty acid synthase (FASN) as a therapeutic target in breast cancer
- (2017) Javier A. Menendez et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- Inhibition of the sterol regulatory element-binding protein pathway suppresses hepatocellular carcinoma by repressing inflammation in mice
- (2017) Na Li et al. HEPATOLOGY
- Acetyl-coenzyme A carboxylase inhibition reduces de novo lipogenesis in overweight male subjects: A randomized, double-blind, crossover study
- (2017) Kathryn Stiede et al. HEPATOLOGY
- Stearoyl-CoA desaturase regulates sorafenib resistance via modulation of ER stress-induced differentiation
- (2017) Mark Kin Fai Ma et al. JOURNAL OF HEPATOLOGY
- SREBP-regulated lipid metabolism: convergent physiology — divergent pathophysiology
- (2017) Hitoshi Shimano et al. Nature Reviews Endocrinology
- Inhibition of hepatic lipogenesis enhances liver tumorigenesis by increasing antioxidant defence and promoting cell survival
- (2017) Marin E. Nelson et al. Nature Communications
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- (2017) Qian Chen et al. Nutrients
- The Burden of Primary Liver Cancer and Underlying Etiologies From 1990 to 2015 at the Global, Regional, and National Level
- (2017) et al. JAMA Oncology
- The Emerging Hallmarks of Cancer Metabolism
- (2016) Natalya N. Pavlova et al. Cell Metabolism
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- (2016) Samir Softic et al. DIGESTIVE DISEASES AND SCIENCES
- Acetyl-coenzyme A carboxylase alpha promotion of glucose-mediated fatty acid synthesis enhances survival of hepatocellular carcinoma in mice and patients
- (2016) Ming-Da Wang et al. HEPATOLOGY
- Global epidemiology of nonalcoholic fatty liver disease-Meta-analytic assessment of prevalence, incidence, and outcomes
- (2016) Zobair M. Younossi et al. HEPATOLOGY
- EASL Clinical Practice Guidelines on the management of benign liver tumours
- (2016) JOURNAL OF HEPATOLOGY
- Inactivation of fatty acid synthase impairs hepatocarcinogenesis driven by AKT in mice and humans
- (2016) Lei Li et al. JOURNAL OF HEPATOLOGY
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- (2016) Dan Cao et al. LIVER INTERNATIONAL
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- (2016) Xiaochao Wei et al. NATURE
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- (2016) Junjie Hu et al. Scientific Reports
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- (2015) Guang-Ming Huang et al. CANCER LETTERS
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- (2015) Jessica Zucman-Rossi et al. GASTROENTEROLOGY
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- (2015) Matthias Lochner et al. TRENDS IN IMMUNOLOGY
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- (2014) Stanley Ching-Cheng Huang et al. NATURE IMMUNOLOGY
- TLR-driven early glycolytic reprogramming via the kinases TBK1-IKKɛ supports the anabolic demands of dendritic cell activation
- (2014) Bart Everts et al. NATURE IMMUNOLOGY
- De novo fatty acid synthesis controls the fate between regulatory T and T helper 17 cells
- (2014) Luciana Berod et al. NATURE MEDICINE
- Expression and roles of fatty acid synthase in hepatocellular carcinoma
- (2014) QIWEI HAO et al. ONCOLOGY REPORTS
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- (2013) K. Muir et al. CANCER RESEARCH
- Hooked on fat: the role of lipid synthesis in cancer metabolism and tumour development
- (2013) F. Baenke et al. Disease Models & Mechanisms
- Stearoyl-CoA desaturase plays an important role in proliferation and chemoresistance in human hepatocellular carcinoma
- (2013) Samiksha Bansal et al. JOURNAL OF SURGICAL RESEARCH
- Single phosphorylation sites in Acc1 and Acc2 regulate lipid homeostasis and the insulin-sensitizing effects of metformin
- (2013) Morgan D Fullerton et al. NATURE MEDICINE
- SCD1 Expression Is Dispensable for Hepatocarcinogenesis Induced by AKT and Ras Oncogenes in Mice
- (2013) Lei Li et al. PLoS One
- Transcriptional Control of Hepatic Lipid Metabolism by SREBP and ChREBP
- (2013) Xu Xu et al. SEMINARS IN LIVER DISEASE
- ATP-Citrate Lyase: A Key Player in Cancer Metabolism
- (2012) N. Zaidi et al. CANCER RESEARCH
- AMP-activated protein kinase and ATP-citrate lyase are two distinct molecular targets for ETC-1002, a novel small molecule regulator of lipid and carbohydrate metabolism
- (2012) Stephen L. Pinkosky et al. JOURNAL OF LIPID RESEARCH
- Fatty acid synthase and liver triglyceride metabolism: Housekeeper or messenger?
- (2011) Anne P.L. Jensen-Urstad et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Inhibition of SREBP by a Small Molecule, Betulin, Improves Hyperlipidemia and Insulin Resistance and Reduces Atherosclerotic Plaques
- (2011) Jing-Jie Tang et al. Cell Metabolism
- AKT (v-akt murine thymoma viral oncogene homolog 1) and N-Ras (neuroblastoma ras viral oncogene homolog) coactivation in the mouse liver promotes rapid carcinogenesis by way of mTOR (mammalian target of rapamycin complex 1), FOXM1 (forkhead box M1)/SKP2,
- (2011) Coral Ho et al. HEPATOLOGY
- The Critical Role of AKT2 in Hepatic Steatosis Induced by PTEN Loss
- (2010) Lina He et al. AMERICAN JOURNAL OF PATHOLOGY
- Stearoyl-CoA desaturase-1: a novel key player in the mechanisms of cell proliferation, programmed cell death and transformation to cancer
- (2010) R. A. Igal CARCINOGENESIS
- Increased Lipogenesis, Induced by AKT-mTORC1-RPS6 Signaling, Promotes Development of Human Hepatocellular Carcinoma
- (2010) Diego F. Calvisi et al. GASTROENTEROLOGY
- De novo fatty-acid synthesis and related pathways as molecular targets for cancer therapy
- (2009) T Mashima et al. BRITISH JOURNAL OF CANCER
- Integrative Transcriptome Analysis Reveals Common Molecular Subclasses of Human Hepatocellular Carcinoma
- (2009) Y. Hoshida et al. CANCER RESEARCH
- Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
- (2009) M. G. Vander Heiden et al. SCIENCE
- Focal Gains of VEGFA and Molecular Classification of Hepatocellular Carcinoma
- (2008) D. Y. Chiang et al. CANCER RESEARCH
- ATP Citrate Lyase: Activation and Therapeutic Implications in Non-Small Cell Lung Cancer
- (2008) T. Migita et al. CANCER RESEARCH
- Activation of lipogenic pathway correlates with cell proliferation and poor prognosis in hepatocellular carcinoma
- (2008) Taro Yamashita et al. JOURNAL OF HEPATOLOGY
- Sorafenib in Advanced Hepatocellular Carcinoma
- (2008) Josep M. Llovet et al. NEW ENGLAND JOURNAL OF MEDICINE
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