AMP-activated protein kinase and ATP-citrate lyase are two distinct molecular targets for ETC-1002, a novel small molecule regulator of lipid and carbohydrate metabolism

Statin Use and Risk of Diabetes Mellitus in Postmenopausal Women in the Women's Health Initiative

(2012) Annie L. Culver   ARCHIVES OF INTERNAL MEDICINE

Methazolamide Is a New Hepatic Insulin Sensitizer That Lowers Blood Glucose In Vivo

(2012) N. Konstantopoulos et al.   DIABETES

Anti-diabetic and anti-adipogenic effects of a novel selective 11β-hydroxysteroid dehydrogenase type 1 inhibitor in the diet-induced obese mice

(2012) Ji Seon Park et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Understanding Statin Use in America and Gaps in Patient Education (USAGE): An internet-based survey of 10,138 current and former statin users

(2012) Jerome D. Cohen et al.   Journal of Clinical Lipidology

ETC-1002 LOWERS LDL-C AND BENEFICIALLY MODULATES OTHER CARDIO-METABOLIC RISK FACTORS IN HYPERCHOLESTEROLEMIC SUBJECTS WITH EITHER NORMAL OR ELEVATED TRIGLYCERIDES

(2012) Christie M. Ballantyne et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Diagnosis, Prevention, and Management of Statin Adverse Effects and Intolerance: Proceedings of a Canadian Working Group Consensus Conference

(2011) G.B. John Mancini et al.   CANADIAN JOURNAL OF CARDIOLOGY

The Logic Linking Protein Acetylation and Metabolism

(2011) Leonard Guarente   Cell Metabolism

Inflammation Is Necessary for Long-Term but Not Short-Term High-Fat Diet-Induced Insulin Resistance

(2011) Y. S. Lee et al.   DIABETES

Suppression of FoxO1 Activity by Long-Chain Fatty Acyl Analogs

(2011) G. Zatara et al.   DIABETES

Hematopoietic AMPK β1 reduces mouse adipose tissue macrophage inflammation and insulin resistance in obesity

(2011) Sandra Galic et al.   JOURNAL OF CLINICAL INVESTIGATION

Clinical and laboratory phenotype of patients experiencing statin intolerance attributable to myalgia

(2011) Leonard J. Harris et al.   Journal of Clinical Lipidology

Anti-inflammatory and hypolipidemic effects of the modified fatty acid tetradecylthioacetic acid in psoriasis – a pilot study

(2011) Tore Morken et al.   SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION

Evaluation of anti-atherosclerotic activities of PPAR-α, PPAR-γ, and LXR agonists in hyperlipidemic atherosclerosis-susceptible F1B hamsters

(2010) Rai Ajit K. Srivastava   ATHEROSCLEROSIS

Management of the Patient with Statin Intolerance

(2010) Byron F. Vandenberg et al.   Current Atherosclerosis Reports

Activation of AMP-activated protein kinase signaling pathway by adiponectin and insulin in mouse adipocytes: requirement of acyl-CoA synthetases FATP1 and Acsl1 and association with an elevation in AMP/ATP ratio

(2010) Qingqing Liu et al.   FASEB JOURNAL

Functional Heterogeneity of CD11c-positive Adipose Tissue Macrophages in Diet-induced Obese Mice

(2010) Pingping Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Deficiency in hepatic ATP-citrate lyase affects VLDL-triglyceride mobilization and liver fatty acid composition in mice

(2010) Qiong Wang et al.   JOURNAL OF LIPID RESEARCH

Anti-hyperlipidemic and insulin sensitizing activities of fenofibrate reduces aortic lipid deposition in hyperlipidemic Golden Syrian hamster

(2010) Rai Ajit K. Srivastava et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Reversible acetylation of PGC-1: connecting energy sensors and effectors to guarantee metabolic flexibility

(2010) E H Jeninga et al.   ONCOGENE

Reversal of Obesity and Insulin Resistance by a Non-Peptidic Glucagon-Like Peptide-1 Receptor Agonist in Diet-Induced Obese Mice

(2010) Min He et al.   PLoS One

A novel direct homogeneous assay for ATP citrate lyase

(2009) Zhengping Ma et al.   JOURNAL OF LIPID RESEARCH

ATP-Citrate Lyase Links Cellular Metabolism to Histone Acetylation

(2009) K. E. Wellen et al.   SCIENCE

AMPK activation by long chain fatty acyl analogs

(2008) Ghadeer Za’tara et al.   BIOCHEMICAL PHARMACOLOGY

Selective versus Total Insulin Resistance: A Pathogenic Paradox

(2008) Michael S. Brown et al.   Cell Metabolism

Genetic predisposition to statin myopathy

(2008) Georgirene D Vladutiu   CURRENT OPINION IN RHEUMATOLOGY

Medical Management of Hyperglycemia in Type 2 Diabetes: A Consensus Algorithm for the Initiation and Adjustment of Therapy: A consensus statement of the American Diabetes Association and the European Association for the Study of Diabetes

(2008) D. M. Nathan et al.   DIABETES CARE

Abrogation of hepatic ATP-citrate lyase protects against fatty liver and ameliorates hyperglycemia in leptin receptor-deficient mice

(2008) Qiong Wang et al.   HEPATOLOGY

Novel black soy peptides with antiobesity effects: activation of leptin-like signaling and AMP-activated protein kinase

(2008) E-H Jang et al.   INTERNATIONAL JOURNAL OF OBESITY

Insulin sensitivity: modulation by nutrients and inflammation

(2008) Simon Schenk et al.   JOURNAL OF CLINICAL INVESTIGATION