Effects of Natural Products on Fructose-Induced Nonalcoholic Fatty Liver Disease (NAFLD)

Dietary fructose as a risk factor for non-alcoholic fatty liver disease (NAFLD)

(2016) Salamah Mohammad Alwahsh et al.   ARCHIVES OF TOXICOLOGY

Polyphenols from hawthorn peels and fleshes differently mitigate dyslipidemia, inflammation and oxidative stress in association with modulation of liver injury in high fructose diet-fed mice

(2016) Xiao Han et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Curcumin prevents inflammatory response, oxidative stress and insulin resistance in high fructose fed male Wistar rats: Potential role of serine kinases

(2016) Nachimuthu Maithilikarpagaselvi et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Betaine prevented fructose-induced NAFLD by regulating LXRα/PPARα pathway and alleviating ER stress in rats

(2016) Chen-Xu Ge et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The Natural Course of Non-Alcoholic Fatty Liver Disease

(2016) Luis Calzadilla Bertot et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Isoorientin Prevents Hyperlipidemia and Liver Injury by Regulating Lipid Metabolism, Antioxidant Capability, and Inflammatory Cytokine Release in High-Fructose-Fed Mice

(2016) Li Yuan et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Dioscoreophyllum cumminsii (Stapf) Diels leaves halt high-fructose induced metabolic syndrome: Hyperglycemia, insulin resistance, inflammation and oxidative stress

(2016) T.O. Ajiboye et al.   JOURNAL OF ETHNOPHARMACOLOGY

Symplocos cochinchinensis enhances insulin sensitivity via the down regulation of lipogenesis and insulin resistance in high energy diet rat model

(2016) Kalathookunnel Antony Antu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Curcumin inhibits hyperlipidemia and hepatic fat accumulation in high-fructose-fed male Wistar rats

(2016) Nachimuthu Maithilikarpagaselvi et al.   PHARMACEUTICAL BIOLOGY

Hypolipidemic effects of flavonoids extracted from Lomatogonium rotatum

(2016) LIDAO BAO et al.   Experimental and Therapeutic Medicine

Dietary Fructose Activates Insulin Signaling and Inflammation in Adipose Tissue: Modulatory Role of Resveratrol

(2016) Mehmet Bilgehan Pektas et al.   Biomed Research International

Lipocalin 2 (LCN2) Expression in Hepatic Malfunction and Therapy

(2016) Anastasia Asimakopoulou et al.   Frontiers in Physiology

Ferulic acid regulates hepatic GLUT2 gene expression in high fat and fructose-induced type-2 diabetic adult male rat

(2015) Akilavalli Narasimhan et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Leptin-induced mitochondrial fusion mediates hepatic lipid accumulation

(2015) W-H Hsu et al.   INTERNATIONAL JOURNAL OF OBESITY

Nonalcoholic fatty liver disease and statins

(2015) Konstantinos Tziomalos et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Fish Oil Decreases Hepatic Lipogenic Genes in Rats Fasted and Refed on a High Fructose Diet

(2015) Gabriela de Castro et al.   Nutrients

Differential Responses of Plasma Adropin Concentrations To Dietary Glucose or Fructose Consumption In Humans

(2015) Andrew A. Butler et al.   Scientific Reports

Geraniol, Alone and in Combination with Pioglitazone, Ameliorates Fructose-Induced Metabolic Syndrome in Rats via the Modulation of Both Inflammatory and Oxidative Stress Status

(2015) Sherehan M. Ibrahim et al.   PLoS One

Dietary Sugar and Body Weight: Have We Reached a Crisis in the Epidemic of Obesity and Diabetes?

(2014) George A. Bray et al.   DIABETES CARE

High-fructose corn syrup-induced hepatic dysfunction in rats: improving effect of resveratrol

(2014) Gokhan Sadi et al.   EUROPEAN JOURNAL OF NUTRITION

Protective effect of thymoquinone against high-fructose diet-induced metabolic syndrome in rats

(2014) Pankaj Prabhakar et al.   EUROPEAN JOURNAL OF NUTRITION

Silymarin ameliorates fructose induced insulin resistance syndrome by reducing de novo hepatic lipogenesis in the rat

(2014) Prem Prakash et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

(−)-Epicatechin mitigates high-fructose-associated insulin resistance by modulating redox signaling and endoplasmic reticulum stress

(2014) Ahmed Bettaieb et al.   FREE RADICAL BIOLOGY AND MEDICINE

Glucose Transporter 8 (GLUT8) Mediates Fructose-inducedde NovoLipogenesis and Macrosteatosis

(2014) Brian J. DeBosch et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Advances in understanding the interrelations between leptin resistance and obesity

(2014) Haitao Pan et al.   PHYSIOLOGY & BEHAVIOR

Acute Post-Bariatric Surgery Increase in Orexin Levels Associates with Preferential Lipid Profile Improvement

(2014) Abhishek Gupta et al.   PLoS One

Combination of Alcohol and Fructose Exacerbates Metabolic Imbalance in Terms of Hepatic Damage, Dyslipidemia, and Insulin Resistance in Rats

(2014) Salamah Mohammad Alwahsh et al.   PLoS One

Mangiferin treatment inhibits hepatic expression of acyl-coenzyme A:diacylglycerol acyltransferase-2 in fructose-fed spontaneously hypertensive rats: a link to amelioration of fatty liver

(2014) Xiaomang Xing et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Diet high in fructose leads to an overexpression of lipocalin-2 in rat fatty liver

(2014) Salamah Mohammad Alwahsh   WORLD JOURNAL OF GASTROENTEROLOGY

Chemical composition of Pleurotus eryngii polysaccharides and their inhibitory effects on high-fructose diet-induced insulin resistance and oxidative stress in mice

(2014) Daoyuan Ren et al.   Food & Function

Metformin: A Rising Star to Fight the Epithelial Mesenchymal Transition in Oncology

(2013) Guislaine Barriere et al.   Anti-Cancer Agents in Medicinal Chemistry

Astaxanthin reduces hepatic endoplasmic reticulum stress and nuclear factor-κB-mediated inflammation in high fructose and high fat diet-fed mice

(2013) Saravanan Bhuvaneswari et al.   CELL STRESS & CHAPERONES

Oxymatrine attenuates hepatic steatosis in non-alcoholic fatty liver disease rats fed with high fructose diet through inhibition of sterol regulatory element binding transcription factor 1 (Srebf1) and activation of peroxisome proliferator activated receptor alpha (Pparα)

(2013) Li-juan Shi et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Oleanolic Acid Diminishes Liquid Fructose-Induced Fatty Liver in Rats: Role of Modulation of Hepatic Sterol Regulatory Element-Binding Protein-1c-Mediated Expression of Genes Responsible for De Novo Fatty Acid Synthesis

(2013) Changjin Liu et al.   Evidence-based Complementary and Alternative Medicine

Dietary fructose in nonalcoholic fatty liver disease

(2013) Miriam B. Vos et al.   HEPATOLOGY

Modulation of hepatic sterol regulatory element-binding protein-1c-mediated gene expression contributes to Salacia oblonga root-elicited improvement of fructose-induced fatty liver in rats

(2013) Lei Liu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Genistein sensitizes hepatic insulin signaling and modulates lipid regulatory genes through p70 ribosomal S6 kinase-1 inhibition in high-fat–high-fructose diet-fed mice

(2013) Elumalai Arunkumar et al.   PHARMACEUTICAL BIOLOGY

Astaxanthin prevents loss of insulin signaling and improves glucose metabolism in liver of insulin resistant mice

(2012) Saravanan Bhuvaneswari et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Fructose metabolism in humans – what isotopic tracer studies tell us

(2012) Sam Z Sun et al.   Nutrition & Metabolism

Dietary β-conglycinin prevents fatty liver induced by a high-fat diet by a decrease in peroxisome proliferator-activated receptor γ2 protein

(2011) Tomomi Yamazaki et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Fructose: a highly lipogenic nutrient implicated in insulin resistance, hepatic steatosis, and the metabolic syndrome

(2010) Mark J. Dekker et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Increased fructose consumption is associated with fibrosis severity in patients with nonalcoholic fatty liver disease

(2010) Manal F. Abdelmalek et al.   HEPATOLOGY

The role of fructose in the pathogenesis of NAFLD and the metabolic syndrome

(2010) Jung Sub Lim et al.   Nature Reviews Gastroenterology & Hepatology

Hypothesis: Could Excessive Fructose Intake and Uric Acid Cause Type 2 Diabetes?

(2009) Richard J. Johnson et al.   ENDOCRINE REVIEWS

Dietary Green Tea Extract Lowers Plasma and Hepatic Triglycerides and Decreases the Expression of Sterol Regulatory Element-Binding Protein-1c mRNA and Its Responsive Genes in Fructose-Fed, Ovariectomized Rats

(2009) Sudeep Shrestha et al.   JOURNAL OF NUTRITION

Fructose consumption as a risk factor for non-alcoholic fatty liver disease

(2008) Xiaosen Ouyang et al.   JOURNAL OF HEPATOLOGY

Epidemiology of non-alcoholic fatty liver disease in China

(2008) Jian-Gao Fan et al.   JOURNAL OF HEPATOLOGY