Sites of Cre‐recombinase activity in mouse lines targeting skeletal cells

Osteoclast fusion and bone loss are restricted by interferon inducible guanylate binding proteins

(2021) David E. Place et al.   Nature Communications

Osteoclasts recycle via osteomorphs during RANKL-stimulated bone resorption

(2021) Michelle M. McDonald et al.   CELL

Cruciate ligament, patellar tendon, and patella formation involves differential cellular sources and dynamics as joint cavitation proceeds

(2020) Yi Zhang et al.   DEVELOPMENTAL DYNAMICS

Erythromyeloid progenitors give rise to a population of osteoclasts that contribute to bone homeostasis and repair

(2020) Yasuhito Yahara et al.   NATURE CELL BIOLOGY

A Wnt-mediated transformation of the bone marrow stromal cell identity orchestrates skeletal regeneration

(2020) Yuki Matsushita et al.   Nature Communications

Regulation of Gdf5 expression in joint remodelling, repair and osteoarthritis

(2020) Karolina Kania et al.   Scientific Reports

Skeletal stem cells: insights into maintaining and regenerating the skeleton

(2020) Maxwell A. Serowoky et al.   DEVELOPMENT

Dissecting the phenotypic and functional heterogeneity of mouse inflammatory osteoclasts by the expression of Cx3cr1

(2020) Maria-Bernadette Madel et al.   eLife

Effects of tamoxifen on tendon homeostasis and healing: Considerations for the use of tamoxifen‐inducible mouse models

(2020) Katherine T. Best et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Identification of the skeletal progenitor cells forming osteophytes in osteoarthritis

(2020) Anke J Roelofs et al.   ANNALS OF THE RHEUMATIC DISEASES

Role of Prx1-expressing skeletal cells and Prx1-expression in fracture repair

(2020) Alessandra Esposito et al.   BONE

TGF‐β/Smad2 signalling regulates enchondral bone formation of Gli1 + periosteal cells during fracture healing

(2020) Chenjie Xia et al.   CELL PROLIFERATION

Periosteum progenitors could stimulate bone regeneration in aged murine bone defect model

(2020) Han Xiao et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Sensitive detection of Cre-mediated recombination using droplet digital PCR reveals Tg(BGLAP-Cre) and Tg(DMP1-Cre) are active in multiple non-skeletal tissues

(2020) Krishnakali Dasgupta et al.   BONE

ScxLin cells directly form a subset of chondrocytes in temporomandibular joint that are sharply increased in Dmp1-null mice

(2020) Chi Ma et al.   BONE

Loss of Smad4 in the scleraxis cell lineage results in postnatal joint contracture

(2020) Saundra Y. Schlesinger et al.   DEVELOPMENTAL BIOLOGY

N-Cadherin-Expressing Bone and Marrow Stromal Progenitor Cells Maintain Reserve Hematopoietic Stem Cells

(2019) Meng Zhao et al.   Cell Reports

Mouse Wnt1-CRE -Rosa Tomato Dental Pulp Stem Cells Directly Contribute to the Calvarial Bone Regeneration Process

(2019) Anne-Margaux Collignon et al.   STEM CELLS

Lkb1 deletion in periosteal mesenchymal progenitors induces osteogenic tumors through mTORC1 activation

(2019) Yujiao Han et al.   JOURNAL OF CLINICAL INVESTIGATION

Characterization of Cre recombinase  mouse lines enabling cell type-specific targeting of postnatal intervertebral discs

(2019) Yixin Zheng et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Aggrecan Hypomorphism Compromises Articular Cartilage Biomechanical Properties and Is Associated with Increased Incidence of Spontaneous Osteoarthritis

(2019) Paolo Alberton et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The platelet‐derived growth factor receptor alpha promoter‐directed expression of cre recombinase in mouse placenta

(2019) Jean‐Sebastien Wattez et al.   DEVELOPMENTAL DYNAMICS

Cleavage factor 25 deregulation contributes to pulmonary fibrosis through alternative polyadenylation

(2019) Tingting Weng et al.   JOURNAL OF CLINICAL INVESTIGATION

Developmental origin, functional maintenance and genetic rescue of osteoclasts

(2019) Christian E. Jacome-Galarza et al.   NATURE

Cell non-autonomous functions of S100a4 drive fibrotic tendon healing

(2019) Jessica E Ackerman et al.   eLife

Tamoxifen administration in pregnant mice can be deleterious to both mother and embryo

(2019) Nikita Ved et al.   LABORATORY ANIMALS

Macrophage hypoxia signaling regulates cardiac fibrosis via Oncostatin M

(2019) Hajime Abe et al.   Nature Communications

Hox11 expressing regional skeletal stem cells are progenitors for osteoblasts, chondrocytes and adipocytes throughout life

(2019) Kyriel M. Pineault et al.   Nature Communications

Requirement for scleraxis in the recruitment of mesenchymal progenitors during embryonic tendon elongation

(2019) Alice H. Huang et al.   DEVELOPMENT

Activation of Skeletal Stem and Progenitor Cells for Bone Regeneration Is Driven by PDGFRβ Signaling

(2019) Anna-Marei Böhm et al.   DEVELOPMENTAL CELL

Regulation of terminal hypertrophic chondrocyte differentiation in Prmt5 mutant mice modeling infantile idiopathic scoliosis

(2019) Zhaoyang Liu et al.   Disease Models & Mechanisms

Downregulation of CFIm25 amplifies dermal fibrosis through alternative polyadenylation

(2019) Tingting Weng et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A Tppp3+Pdgfra+ tendon stem cell population contributes to regeneration and reveals a shared role for PDGF signalling in regeneration and fibrosis

(2019) Tyler Harvey et al.   NATURE CELL BIOLOGY

Tamoxifen-independent recombination of reporter genes limits lineage tracing and mosaic analysis using CreERT2 lines

(2019) A. Álvarez-Aznar et al.   TRANSGENIC RESEARCH

Aging aggravates intervertebral disc degeneration by regulating transcription factors toward chondrogenesis

(2019) Matthew J. Silva et al.   FASEB JOURNAL

Leptin receptor–expressing cells represent a distinct subpopulation of notochord-derived cells and are essential for disc homoeostasis

(2019) Bo Gao et al.   Journal of Orthopaedic Translation

Targeting Hypoxia-Inducible Factor-1α/Pyruvate Dehydrogenase Kinase 1 Axis by Dichloroacetate Suppresses Bleomycin-induced Pulmonary Fibrosis

(2018) Justin Goodwin et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

The Tumor Necrosis Factor Superfamily Member RANKL Suppresses Effector Cytokine Production in Group 3 Innate Lymphoid Cells

(2018) Jennifer K. Bando et al.   IMMUNITY

Activation of αSMA expressing perivascular cells during reactionary dentinogenesis

(2018) I. Vidovic- Zdrilic et al.   INTERNATIONAL ENDODONTIC JOURNAL

Cell type-specific effects of Notch signaling activation on intervertebral discs: Implications for intervertebral disc degeneration

(2018) Yixin Zheng et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Vhl deletion in osteoblasts boosts cellular glycolysis and improves global glucose metabolism

(2018) Naomi Dirckx et al.   JOURNAL OF CLINICAL INVESTIGATION

Mouse Cre Models for the Study of Bone Diseases

(2018) Sarah L. Dallas et al.   Current Osteoporosis Reports

Midface and upper airway dysgenesis in FGFR2-craniosynostosis involves multiple tissue-specific and cell cycle effects

(2018) Greg Holmes et al.   DEVELOPMENT

Discovery of a periosteal stem cell mediating intramembranous bone formation

(2018) Shawon Debnath et al.   NATURE

Erythro-myeloid progenitors contribute endothelial cells to blood vessels

(2018) Alice Plein et al.   NATURE

A Novel Mouse Model for Cilia-Associated Cardiovascular Anomalies with a High Penetrance of Total Anomalous Pulmonary Venous Return

(2018) Tara A. Burns et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

Resting zone of the growth plate houses a unique class of skeletal stem cells

(2018) Koji Mizuhashi et al.   NATURE

Autocrine regulation of mesenchymal progenitor cell fates orchestrates tooth eruption

(2018) Akira Takahashi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Induction of Lrp5 HBM-causing mutations in Cathepsin-K expressing cells alters bone metabolism

(2018) Kyung Shin Kang et al.   BONE

Male germline recombination of a conditional allele by the widely used Dermo1-cre (Twist2-cre) transgene

(2017) Yun He et al.   GENESIS

Dwarfism in homozygous Agc1CreERT mice is associated with decreased expression of aggrecan

(2017) Harunur Rashid et al.   GENESIS

Bone marrow adipocytes promote the regeneration of stem cells and haematopoiesis by secreting SCF

(2017) Bo O. Zhou et al.   NATURE CELL BIOLOGY

Diverse contribution of Col2a1 -expressing cells to the craniofacial skeletal cell lineages

(2017) N. Sakagami et al.   Orthodontics & Craniofacial Research

Gli1 identifies osteogenic progenitors for bone formation and fracture repair

(2017) Yu Shi et al.   Nature Communications

Joint morphogenetic cells in the adult mammalian synovium

(2017) Anke J. Roelofs et al.   Nature Communications

The minor collagens in articular cartilage

(2017) Yunyun Luo et al.   Protein & Cell

Osteocalcin expressing cells from tendon sheaths in mice contribute to tendon repair by activating Hedgehog signaling

(2017) Yi Wang et al.   eLife

Unintended targeting of Dmp1-Cre reveals a critical role for Bmpr1a signaling in the gastrointestinal mesenchyme of adult mice

(2017) Joohyun Lim et al.   Bone Research

Promoter Specificity and Efficacy in Conditional and Inducible Transgenic Targeting of Lung Macrophages

(2017) Alexandra L. McCubbrey et al.   Frontiers in Immunology

Novel Model of Tendon Regeneration Reveals Distinct Cell Mechanisms Underlying Regenerative and Fibrotic Tendon Healing

(2017) Kristen Howell et al.   Scientific Reports

Scleraxis is required for maturation of tissue domains for proper integration of the musculoskeletal system

(2017) Yuki Yoshimoto et al.   Scientific Reports

Osteogenic potential of alpha smooth muscle actin expressing muscle resident progenitor cells

(2016) Brya G. Matthews et al.   BONE

Murine supraspinatus tendon injury model to identify the cellular origins of rotator cuff healing

(2016) Ryu Yoshida et al.   CONNECTIVE TISSUE RESEARCH

Neurons exhibitLyz2promoter activity in vivo: Implications for using LysM-Cre mice in myeloid cell research

(2016) Johannes Orthgiess et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Targeting of Mesenchymal Stromal Cells byCre-Recombinase Transgenes Commonly Used to Target Osteoblast Lineage Cells

(2016) Jingzhu Zhang et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Increased EPO Levels Are Associated With Bone Loss in Mice Lacking PHD2 in EPO-Producing Cells

(2016) Martina Rauner et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Inflammatory Osteoclasts Prime TNFα-Producing CD4+T Cells and Express CX3CR1

(2016) Lidia Ibáñez et al.   JOURNAL OF BONE AND MINERAL RESEARCH

αSMA-Expressing Perivascular Cells Represent Dental Pulp Progenitors In Vivo

(2016) I. Vidovic et al.   JOURNAL OF DENTAL RESEARCH

Inducible targeting of cDCs and their subsets in vivo

(2016) Jakob Loschko et al.   JOURNAL OF IMMUNOLOGICAL METHODS

PPAR-γ regulates pharmacological but not physiological or pathological osteoclast formation

(2016) Wei Zou et al.   NATURE MEDICINE

Col2-Cre and tamoxifen-inducible Col2-CreER target different cell populations in the knee joint

(2016) M. Nagao et al.   OSTEOARTHRITIS AND CARTILAGE

Evaluating Tissue-Specific Recombination in a Pdgfrα-CreERT2 Transgenic Mouse Line

(2016) Megan O’Rourke et al.   PLoS One

Specification of tissue-resident macrophages during organogenesis

(2016) E. Mass et al.   SCIENCE

Sutures Possess Strong Regenerative Capacity for Calvarial Bone Injury

(2016) Shery Park et al.   STEM CELLS AND DEVELOPMENT

Ras signaling regulates osteoprogenitor cell proliferation and bone formation

(2016) Garyfallia Papaioannou et al.   Cell Death & Disease

TGF-β Signaling Regulates Cementum Formation through Osterix Expression

(2016) Hwajung Choi et al.   Scientific Reports

CathepsinKCre mediated deletion of βcatenin results in dramatic loss of bone mass by targeting both osteoclasts and osteoblastic cells

(2016) Paula Ruiz et al.   Scientific Reports

Joint Development Involves a Continuous Influx of Gdf5-Positive Cells

(2016) Yulia Shwartz et al.   Cell Reports

PI3K p110β subunit in leptin receptor expressing cells is required for the acute hypophagia induced by endotoxemia

(2016) Beatriz C. Borges et al.   Molecular Metabolism

Lineage tracking of mesenchymal and endothelial progenitors in BMP-induced bone formation

(2015) Mille Kolind et al.   BONE

Optimizing tamoxifen-inducible Cre/loxp system to reduce tamoxifen effect on bone turnover in long bones of young mice

(2015) Zhendong A. Zhong et al.   BONE

Gremlin 1 Identifies a Skeletal Stem Cell with Bone, Cartilage, and Reticular Stromal Potential

(2015) Daniel L. Worthley et al.   CELL

Regulators of G protein signaling 12 promotes osteoclastogenesis in bone remodeling and pathological bone loss

(2015) X Yuan et al.   CELL DEATH AND DIFFERENTIATION

Perivascular Gli1+ Progenitors Are Key Contributors to Injury-Induced Organ Fibrosis

(2015) Rafael Kramann et al.   Cell Stem Cell

Mesenchymal fibroblast growth factor receptor signaling regulates palatal shelf elevation during secondary palate formation

(2015) Kai Yu et al.   DEVELOPMENTAL DYNAMICS

FGFR1 signaling in hypertrophic chondrocytes is attenuated by the Ras-GAP neurofibromin during endochondral bone formation

(2015) Matthew R. Karolak et al.   HUMAN MOLECULAR GENETICS

MBTPS1/SKI-1/S1P proprotein convertase is required for ECM signaling and axial elongation during somitogenesis and vertebral development

(2015) A. Achilleos et al.   HUMAN MOLECULAR GENETICS

C-Myb+ Erythro-Myeloid Progenitor-Derived Fetal Monocytes Give Rise to Adult Tissue-Resident Macrophages

(2015) Guillaume Hoeffel et al.   IMMUNITY

Targeted Deletion of Autophagy Genes Atg5 or Atg7 in the Chondrocytes Promotes Caspase-Dependent Cell Death and Leads to Mild Growth Retardation

(2015) Karuna K Vuppalapati et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Deletion of Rac in Mature Osteoclasts Causes Osteopetrosis, an Age-Dependent Change in Osteoclast Number, and a Reduced Number of Osteoblasts In Vivo

(2015) Meiling Zhu et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Wntless Regulates Dentin Apposition and Root Elongation in the Mandibular Molar

(2015) C.H. Bae et al.   JOURNAL OF DENTAL RESEARCH

Osterix Regulates Tooth Root Formation in a Site-specific Manner

(2015) T.H. Kim et al.   JOURNAL OF DENTAL RESEARCH

Disruption of Tgfbr2 in Odontoblasts Leads to Aberrant Pulp Calcification

(2015) Y.H. Ahn et al.   JOURNAL OF DENTAL RESEARCH

Wild-type microglia do not reverse pathology in mouse models of Rett syndrome

(2015) Jieqi Wang et al.   NATURE

The suture provides a niche for mesenchymal stem cells of craniofacial bones

(2015) Hu Zhao et al.   NATURE CELL BIOLOGY

Erratum: Corrigendum: Asfotase-α improves bone growth, mineralization and strength in mouse models of neurofibromatosis type-1

(2015) Jean de la Croix Ndong et al.   NATURE MEDICINE

DNA methyltransferase 3a regulates osteoclast differentiation by coupling to an S-adenosylmethionine–producing metabolic pathway

(2015) Keizo Nishikawa et al.   NATURE MEDICINE

Aryl Hydrocarbon Receptors in Osteoclast Lineage Cells Are a Negative Regulator of Bone Mass

(2015) Tai-yong Yu et al.   PLoS One

Inactivation of the Progesterone Receptor in Mx1+ Cells Potentiates Osteogenesis in Calvaria but Not in Long Bone

(2015) Zhendong A. Zhong et al.   PLoS One

Identification of aPrg4-Expressing Articular Cartilage Progenitor Cell Population in Mice

(2015) Elena Kozhemyakina et al.   Arthritis & Rheumatology

Dual pathways to endochondral osteoblasts: a novel chondrocyte-derived osteoprogenitor cell identified in hypertrophic cartilage

(2015) J. Park et al.   Biology Open

Highly Selective In Vivo Labeling of Subcutaneous White Adipocyte Precursors with Prx1-Cre

(2015) Joan Sanchez-Gurmaches et al.   Stem Cell Reports

Osteocytes, not Osteoblasts or Lining Cells, are the Main Source of the RANKL Required for Osteoclast Formation in Remodeling Bone

(2015) Jinhu Xiong et al.   PLoS One

Osterix-Cre Transgene Causes Craniofacial Bone Development Defect

(2014) Li Wang et al.   CALCIFIED TISSUE INTERNATIONAL

Leptin-Receptor-Expressing Mesenchymal Stromal Cells Represent the Main Source of Bone Formed by Adult Bone Marrow

(2014) Bo O. Zhou et al.   Cell Stem Cell

Secretion of Shh by a Neurovascular Bundle Niche Supports Mesenchymal Stem Cell Homeostasis in the Adult Mouse Incisor

(2014) Hu Zhao et al.   Cell Stem Cell

Mouse limb skeletal growth and synovial joint development are coordinately enhanced by Kartogenin

(2014) Rebekah S. Decker et al.   DEVELOPMENTAL BIOLOGY

Vasculature-Associated Cells Expressing Nestin in Developing Bones Encompass Early Cells in the Osteoblast and Endothelial Lineage

(2014) Noriaki Ono et al.   DEVELOPMENTAL CELL

Osterix Marks Distinct Waves of Primitive and Definitive Stromal Progenitors during Bone Marrow Development

(2014) Toshihide Mizoguchi et al.   DEVELOPMENTAL CELL

Tartrate-resistant acid phosphatase (TRAP) co-localizes with receptor activator of NF-KB ligand (RANKL) and osteoprotegerin (OPG) in lysosomal-associated membrane protein 1 (LAMP1)-positive vesicles in rat osteoblasts and osteocytes

(2014) L. B. Solberg et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Periosteal PTHrP regulates cortical bone modeling during linear growth in mice

(2014) Meina Wang et al.   JOURNAL OF ANATOMY

Comparative analysis of the efficiency and specificity of myeloid-Cre deleting strains using ROSA-EYFP reporter mice

(2014) Clare L. Abram et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Tissue-resident macrophages originate from yolk-sac-derived erythro-myeloid progenitors

(2014) Elisa Gomez Perdiguero et al.   NATURE

A subset of chondrogenic cells provides early mesenchymal progenitors in growing bones

(2014) Noriaki Ono et al.   NATURE CELL BIOLOGY

Osx-Cre Targets Multiple Cell Types besides Osteoblast Lineage in Postnatal Mice

(2014) Jianquan Chen et al.   PLoS One

Lineage Tracing of Resident Tendon Progenitor Cells during Growth and Natural Healing

(2014) Nathaniel A. Dyment et al.   PLoS One

Hypertrophic chondrocytes can become osteoblasts and osteocytes in endochondral bone formation

(2014) L. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Skeletal defects in Osterix-Cre transgenic mice

(2014) Wei Huang et al.   TRANSGENIC RESEARCH

Chondrocytes Transdifferentiate into Osteoblasts in Endochondral Bone during Development, Postnatal Growth and Fracture Healing in Mice

(2014) Xin Zhou et al.   PLoS Genetics

The neural crest is a source of mesenchymal stem cells with specialized hematopoietic stem cell niche function

(2014) Joan Isern et al.   eLife

Characterization of Cre Recombinase Activity for In Vivo Targeting of Adipocyte Precursor Cells

(2014) Katherine C. Krueger et al.   Stem Cell Reports

Prx1 and 3.2kb Col1a1 promoters target distinct bone cell populations in transgenic mice

(2013) Zhufeng Ouyang et al.   BONE

Scx+/Sox9+ progenitors contribute to the establishment of the junction between cartilage and tendon/ligament

(2013) Y. Sugimoto et al.   DEVELOPMENT

Reporter Mouse Lines for Fluorescence Imaging

(2013) Takaya Abe et al.   DEVELOPMENT GROWTH & DIFFERENTIATION

The widely used Wnt1-Cre transgene causes developmental phenotypes by ectopic activation of Wnt signaling

(2013) Ace E. Lewis et al.   DEVELOPMENTAL BIOLOGY

Generation and characterization ofScxCretransgenic mice

(2013) Yuki Sugimoto et al.   GENESIS

Wnt Signaling Regulates Pulp Volume and Dentin Thickness

(2013) Won Hee Lim et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Inactivation ofVhlin Osteochondral Progenitor Cells Causes High Bone Mass Phenotype and Protects Against Age-Related Bone Loss in Adult Mice

(2013) Tujun Weng et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Specificity and efficiency of reporter expression in adult neural progenitors vary substantially among nestin-CreERT2lines

(2013) Min-Yu Sun et al.   JOURNAL OF COMPARATIVE NEUROLOGY

In vivo Identification of Periodontal Progenitor Cells

(2013) H. Roguljic et al.   JOURNAL OF DENTAL RESEARCH

Colony-stimulating factor 1 receptor (CSF1R) signaling in injured neurons facilitates protection and survival

(2013) Jian Luo et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CXCL12 in early mesenchymal progenitors is required for haematopoietic stem-cell maintenance

(2013) Adam Greenbaum et al.   NATURE

Ptpn11 deletion in a novel progenitor causes metachondromatosis by inducing hedgehog signalling

(2013) Wentian Yang et al.   NATURE

Polyphosphate-Mediated Inhibition of Tartrate-Resistant Acid Phosphatase and Suppression of Bone Resorption of Osteoclasts

(2013) Kana Harada et al.   PLoS One

In vitro and in vivo approaches to study osteocyte biology

(2012) Ivo Kalajzic et al.   BONE

Endogenous Bone Marrow MSCs Are Dynamic, Fate-Restricted Participants in Bone Maintenance and Regeneration

(2012) Dongsu Park et al.   Cell Stem Cell

Fate Mapping Reveals Origins and Dynamics of Monocytes and Tissue Macrophages under Homeostasis

(2012) Simon Yona et al.   IMMUNITY

β-catenin promotes bone formation and suppresses bone resorption in postnatal growing mice

(2012) Jianquan Chen et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Wnt5a-Ror2 signaling between osteoblast-lineage cells and osteoclast precursors enhances osteoclastogenesis

(2012) Kazuhiro Maeda et al.   NATURE MEDICINE

Transgenic Mice for a Tamoxifen-Induced, Conditional Expression of the Cre Recombinase in Osteoclasts

(2012) Maria Arantzazu Sanchez-Fernandez et al.   PLoS One

Cathepsin K-Cre Causes Unexpected Germline Deletion of Genes in Mice

(2012) Crystal L. Winkeler et al.   PLoS One

Origins and Properties of Dental, Thymic, and Bone Marrow Mesenchymal Cells and Their Stem Cells

(2012) Yukiya Komada et al.   PLoS One

In vivo expression of Osterix in mature granule cells of adult mouse olfactory bulb

(2011) Ji-Soo Park et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Constitutive stabilization of ß-catenin in the dental mesenchyme leads to excessive dentin and cementum formation

(2011) Tak-Heun Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

All Hematopoietic Cells Develop from Hematopoietic Stem Cells through Flk2/Flt3-Positive Progenitor Cells

(2011) Scott W. Boyer et al.   Cell Stem Cell

Ectopic Expression of Col2.3 and Col3.6 Promoters in the Brain and Association with Leptin Signaling

(2011) Erica L. Scheller et al.   CELLS TISSUES ORGANS

Characterization of Pdgfrb-Cre transgenic mice reveals reduction of ROSA26 reporter activity in remodeling arteries

(2011) Anne S. Cuttler et al.   GENESIS

Mice lacking Nf1 in osteochondroprogenitor cells display skeletal dysplasia similar to patients with neurofibromatosis type I

(2011) Weixi Wang et al.   HUMAN MOLECULAR GENETICS

Genetic evidence points to an osteocalcin-independent influence of osteoblasts on energy metabolism

(2011) Yoshihiro Yoshikawa et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Cell autonomous requirement of connexin 43 for osteocyte survival: Consequences for endocortical resorption and periosteal bone formation

(2011) Nicoletta Bivi et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Targeted ablation of the PTH/PTHrP receptor in osteocytes impairs bone structure and homeostatic calcemic responses

(2011) William F Powell et al.   JOURNAL OF ENDOCRINOLOGY

CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis

(2011) Bin-Zhi Qian et al.   NATURE

Matrix-embedded cells control osteoclast formation

(2011) Jinhu Xiong et al.   NATURE MEDICINE

In Vivo Fate Mapping Identifies Mesenchymal Progenitor Cells

(2011) Danka Grcevic et al.   STEM CELLS

Decreased body weight in young Osterix-Cre transgenic mice results in delayed cortical bone expansion and accrual

(2011) Rachel A. Davey et al.   TRANSGENIC RESEARCH

Glucocorticoids Suppress Bone Formation by Attenuating Osteoblast Differentiation via the Monomeric Glucocorticoid Receptor

(2010) Alexander Rauch et al.   Cell Metabolism

Synovial joint formation requires local Ext1 expression and heparan sulfate production in developing mouse embryo limbs and spine

(2010) Christina Mundy et al.   DEVELOPMENTAL BIOLOGY

Osteoblast Precursors, but Not Mature Osteoblasts, Move into Developing and Fractured Bones along with Invading Blood Vessels

(2010) Christa Maes et al.   DEVELOPMENTAL CELL

Sox9-expressing precursors are the cellular origin of the cruciate ligament of the knee joint and the limb tendons

(2010) Tsunemitsu Soeda et al.   GENESIS

Generation of transgenic mice for conditional overexpression of Sox9

(2010) Youngwoo Kim et al.   JOURNAL OF BONE AND MINERAL METABOLISM

Osteoclast-specific inactivation of the integrin-linked kinase (ILK) inhibits bone resorption

(2010) Tanya Dossa et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Mesenchymal and haematopoietic stem cells form a unique bone marrow niche

(2010) Simón Méndez-Ferrer et al.   NATURE

NG2+ CNS Glial Progenitors Remain Committed to the Oligodendrocyte Lineage in Postnatal Life and following Neurodegeneration

(2010) Shin H. Kang et al.   NEURON

A Novel Mouse Model of Inflammatory Bowel Disease Links Mammalian Target of Rapamycin-Dependent Hyperproliferation of Colonic Epithelium to Inflammation-Associated Tumorigenesis

(2009) Lin Deng et al.   AMERICAN JOURNAL OF PATHOLOGY

Mice expressing GFP and CreER in osteochondro progenitor cells in the periosteum

(2009) Aya Kawanami et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Bone Ridge Patterning during Musculoskeletal Assembly Is Mediated through SCX Regulation of Bmp4 at the Tendon-Skeleton Junction

(2009) Einat Blitz et al.   DEVELOPMENTAL CELL

Tubulin polymerization-promoting protein family member 3, Tppp3, is a specific marker of the differentiating tendon sheath and synovial joints

(2009) Julia A. Staverosky et al.   DEVELOPMENTAL DYNAMICS

Osteoclast migration on phosphorylated osteopontin is regulated by endogenous tartrate-resistant acid phosphatase

(2009) Barbro Ek-Rylander et al.   EXPERIMENTAL CELL RESEARCH

Generation of aggrecan-CreERT2 knockin mice for inducible Cre activity in adult cartilage

(2009) Stephen P. Henry et al.   GENESIS

Lubricin Distribution in the Human Intervertebral Disc

(2009) Kristy M Shine et al.   JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME

Disruption of Smad4 in Odontoblasts Causes Multiple Keratocystic Odontogenic Tumors and Tooth Malformation in Mice

(2009) Y. Gao et al.   MOLECULAR AND CELLULAR BIOLOGY

Sphingosine-1-phosphate mobilizes osteoclast precursors and regulates bone homeostasis

(2009) Masaru Ishii et al.   NATURE

A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

(2009) Linda Madisen et al.   NATURE NEUROSCIENCE

Conditional mouse osteosarcoma, dependent on p53 loss and potentiated by loss of Rb, mimics the human disease

(2008) C. R. Walkley et al.   GENES & DEVELOPMENT

Smad7 Inhibits Chondrocyte Differentiation at Multiple Steps during Endochondral Bone Formation and Down-regulates p38 MAPK Pathways

(2008) Takao Iwai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mineralization and Bone Resorption Are Regulated by the Androgen Receptor in Male Mice

(2008) Cherie Chiang et al.   JOURNAL OF BONE AND MINERAL RESEARCH

The stream of precursors that colonizes the thymus proceeds selectively through the early T lineage precursor stage of T cell development

(2008) Claudia Benz et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Collagen1α1 promoter drives the expression of Cre recombinase in osteoblasts of transgenic mice

(2008) Lagabaiyila Zha et al.   Journal of Genetics and Genomics

The presence and distribution of lubricin in the caprine intervertebral disc

(2008) Kristy M. Shine et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Col2-Cre recombinase is co-expressed with endogenous type II collagen in embryonic renal epithelium and drives development of polycystic kidney disease following inactivation of ciliary genes

(2008) Elona Kolpakova-Hart et al.   MATRIX BIOLOGY

Specific expression of Cre recombinase in hypertrophic cartilage under the control of a BAC-Col10a1 promoter

(2008) Sonja Gebhard et al.   MATRIX BIOLOGY

PDGFRA/NG2 glia generate myelinating oligodendrocytes and piriform projection neurons in adult mice

(2008) Leanne E Rivers et al.   NATURE NEUROSCIENCE

Metastatic osteosarcoma induced by inactivation of Rb and p53 in the osteoblast lineage

(2008) S. D. Berman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cathepsin K inhibitors prevent matrix-derived growth factor degradation by human osteoclasts

(2007) Karen Fuller et al.   BONE