Cell type-specific effects of Notch signaling activation on intervertebral discs: Implications for intervertebral disc degeneration

Pharmacological inhibition of S6K1 impairs self-renewal and osteogenic differentiation of bone marrow stromal cells

(2017) Xiaohui Gu et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Osteoarthritis: toward a comprehensive understanding of pathological mechanism

(2017) Di Chen et al.   Bone Research

mTORC1 Signaling Promotes Limb Bud Cell Growth and Chondrogenesis

(2016) Ming Jiang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Notch signaling in postnatal joint chondrocytes, but not subchondral osteoblasts, is required for articular cartilage and joint maintenance

(2016) Z. Liu et al.   OSTEOARTHRITIS AND CARTILAGE

Rho-Associated Kinase Inhibitor Immortalizes Rat Nucleus Pulposus and Annulus Fibrosus Cells

(2016) Chun-do Oh et al.   SPINE

A dual role for NOTCH signaling in joint cartilage maintenance and osteoarthritis

(2015) Zhaoyang Liu et al.   Science Signaling

A dual role for NOTCH signaling in joint cartilage maintenance and osteoarthritis

(2015) Zhaoyang Liu et al.   Science Signaling

Inflammatory Cytokines Induce NOTCH Signaling in Nucleus Pulposus Cells

(2013) Hua Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Notch signaling at a glance

(2013) K. Hori et al.   JOURNAL OF CELL SCIENCE

Lactoferricin mediates anti-inflammatory and anti-catabolic effects via inhibition of IL-1 and LPS activity in the intervertebral disc

(2013) Jae-Sung Kim et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Role of cytokines in intervertebral disc degeneration: pain and disc content

(2013) Makarand V. Risbud et al.   Nature Reviews Rheumatology

Interleukin 6 mediates selected effects of Notch in chondrocytes

(2013) S. Zanotti et al.   OSTEOARTHRITIS AND CARTILAGE

Conditional activation of β-catenin signaling in mice leads to severe defects in intervertebral disc tissue

(2012) Meina Wang et al.   ARTHRITIS AND RHEUMATISM

Recent progress in understanding molecular mechanisms of cartilage degeneration during osteoarthritis

(2011) Meina Wang et al.   Annals of the New York Academy of Sciences

Hypoxia activates the notch signaling pathway in cells of the intervertebral disc: Implications in degenerative disc disease

(2011) Akihiko Hiyama et al.   ARTHRITIS AND RHEUMATISM

Tracing notochord-derived cells using a Noto-cre mouse: implications for intervertebral disc development

(2011) M. R. McCann et al.   Disease Models & Mechanisms

Lactoferricin mediates anabolic and anti-catabolic effects in the intervertebral disc

(2011) Jae-Sung Kim et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The role of the cartilage matrix in osteoarthritis

(2010) Dick Heinegård et al.   Nature Reviews Rheumatology

Notch pathway regulation of chondrocyte differentiation and proliferation during appendicular and axial skeleton development

(2009) T. J. Mead et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of catabolic gene expression in normal and degenerate human intervertebral disc cells: implications for the pathogenesis of intervertebral disc degeneration

(2009) S Jane Millward-Sadler et al.   ARTHRITIS RESEARCH & THERAPY

Repair, regenerative and supportive therapies of the annulus fibrosus: achievements and challenges

(2008) Johannes Leendert Bron et al.   EUROPEAN SPINE JOURNAL

Age-Related Changes in the Extracellular Matrix of Nucleus Pulposus and Anulus Fibrosus of Human Intervertebral Disc

(2008) Kern Singh et al.   SPINE