Fructose and the Liver

Role of Oxidative Stress in the Pathogenesis of Non-Alcoholic Fatty Liver Disease: Implications for Prevention and Therapy

(2021) Johanna C. Arroyave-Ospina et al.   Antioxidants

Impact of liver-specific GLUT8 silencing on fructose-induced inflammation and omega-oxidation.

(2021) Marta G. Novelle et al.   iScience

Dual regulation of TxNIP by ChREBP and FoxO1 in liver

(2021) Benedicte Noblet et al.   iScience

Fructose and hepatic insulin resistance

(2020) Samir Softic et al.   CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES

Liver ChREBP Protects Against Fructose-induced Glycogenic Hepatotoxicity by Regulating L-type Pyruvate Kinase

(2020) Jian-Hui Shi et al.   DIABETES

Elevated fructose and uric acid via aldose reductase contribute to experimental and human alcoholic liver disease

(2020) Min Wang et al.   HEPATOLOGY

Cellular Interplay as a Consequence of Inflammatory Signals Leading to Liver Fibrosis Development

(2020) Simona-Rebeca Ignat et al.   Cells

Acetyl-CoA carboxylase inhibition disrupts metabolic reprogramming during hepatic stellate cell activation

(2020) Jamie Bates et al.   JOURNAL OF HEPATOLOGY

Cell-Type–Specific, Ketohexokinase-Dependent Induction by Fructose of Lipogenic Gene Expression in Mouse Small Intestine

(2020) Arwa Al-Jawadi et al.   JOURNAL OF NUTRITION

Chronic Stress Potentiates High Fructose‐Induced Lipogenesis in Rat Liver and Kidney

(2020) Danijela Vojnović Milutinović et al.   MOLECULAR NUTRITION & FOOD RESEARCH

The Role of Dietary Advanced Glycation End Products in Metabolic Dysfunction

(2020) Domenico Sergi et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Dietary fructose feeds hepatic lipogenesis via microbiota-derived acetate

(2020) Steven Zhao et al.   NATURE

Determining the role for uric acid in non-alcoholic steatohepatitis development and the utility of urate metabolites in diagnosis: An opinion review

(2020) Paul Brennan et al.   WORLD JOURNAL OF GASTROENTEROLOGY

The Emerging Role of MicroRNAs in NAFLD: Highlight of MicroRNA-29a in Modulating Oxidative Stress, Inflammation, and Beyond

(2020) Hung-Yu Lin et al.   Cells

Deletion of Fructokinase in the Liver or in the Intestine Reveals Differential Effects on Sugar-Induced Metabolic Dysfunction

(2020) Ana Andres-Hernando et al.   Cell Metabolism

Maternal fructose consumption down-regulates Lxra expression via miR-206-mediated regulation

(2020) Mirai Yamazaki et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Comparison of MAFLD and NAFLD diagnostic criteria in real world

(2020) Su Lin et al.   LIVER INTERNATIONAL

Hepatic cholesterol synthesis and lipoprotein levels impaired by dietary fructose and saturated fatty acids in mice: Insight on PCSK9 and CD36

(2020) Reyhan Nergiz-Unal et al.   NUTRITION

High Serum Uric Acid Levels Could Be a Risk Factor of Hepatocellular Carcinoma Recurrences

(2020) Masamichi Hayashi et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

The obesity epidemic in the face of homeostatic body weight regulation: What went wrong and how can it be fixed?

(2020) Hans-Rudolf Berthoud et al.   PHYSIOLOGY & BEHAVIOR

The Effect of Fructose Feeding on Intestinal Triacylglycerol Production and De Novo Fatty Acid Synthesis in Humans

(2020) Simon Steenson et al.   Nutrients

Fructose contributes to the Warburg effect for cancer growth

(2020) Takahiko Nakagawa et al.   Cancer & Metabolism

High fat diet-triggered non-alcoholic fatty liver disease: A review of proposed mechanisms

(2020) Cai-Yu Lian et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Thioredoxin Interacting Protein Is Required for a Chronic Energy-Rich Diet to Promote Intestinal Fructose Absorption

(2020) Anu Shah et al.   iScience

Fructose Metabolism in Cancer

(2020) Nils Krause et al.   Cells

Molecular Mechanisms That Link Oxidative Stress, Inflammation, and Fibrosis in the Liver

(2020) Erika Ramos-Tovar et al.   Antioxidants

The NRF2, Thioredoxin, and Glutathione System in Tumorigenesis and Anticancer Therapies

(2020) Morana Jaganjac et al.   Antioxidants

Impact of the New Definition of Metabolic Associated Fatty Liver Disease on the Epidemiology of the Disease

(2020) Vincent Wai-Sun Wong et al.   Clinical Gastroenterology and Hepatology

Uric acid activates aldose reductase and the polyol pathway for endogenous fructose and fat production causing development of fatty liver in rats

(2019) Laura G. Sánchez-Lozada et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Role of Nrf2 in Liver Disease: Novel Molecular Mechanisms and Therapeutic Approaches

(2019) Dongwei Xu et al.   Frontiers in Pharmacology

High-fructose drinks affect microRNAs expression differently in lean and obese mice

(2019) Barbora Hanousková et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

TXNIP-mediated nuclear factor-κB signaling pathway and intracellular shifting of TXNIP in uric acid-induced NLRP3 inflammasome

(2019) Seong-Kyu Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Critical Role of SREBP-1c Large-VLDL Pathway in Environment-Induced Hypertriglyceridemia of Apo AV Deficiency

(2019) Mikio Takanashi et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Endogenous fructose production

(2019) Ana Andres-Hernando et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Fructose Promotes Leaky Gut, Endotoxemia and Liver Fibrosis through CYP 2E1‐Mediated Oxidative and Nitrative Stress

(2019) Young‐Eun Cho et al.   HEPATOLOGY

Role of NF-kB RelB in Aryl Hydrocarbon Receptor-Mediated Ligand Specific Effects

(2019) Yasuhiro Ishihara et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Calcium Signaling As a Therapeutic Target for Liver Steatosis

(2019) Eunüs S. Ali et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Hepatic transcriptomics analysis reveals that fructose intervention downregulated xenobiotics metabolizing enzymes through aryl hydrocarbon receptor signaling suppression in C57BL/6N mice

(2019) Jeong Hoon Pan et al.   BRITISH JOURNAL OF NUTRITION

Fructose Promotion of Intestinal and Liver Injury: A Sugar by Any Other Name That Isn't So Sweet

(2019) Lindsey Kennedy et al.   HEPATOLOGY

Identification of the fructose transporter GLUT5 (SLC2A5) as a novel target of nuclear receptor LXR

(2019) Irene Zwarts et al.   Scientific Reports

Effects of Fructose or Glucose on Circulating ApoCIII and Triglyceride and Cholesterol Content of Lipoprotein Subfractions in Humans

(2019) Bettina Hieronimus et al.   Journal of Clinical Medicine

Free radicals, antioxidants, nuclear factor‐E2‐related factor‐2 and liver damage

(2019) Erika Ramos‐Tovar et al.   JOURNAL OF APPLIED TOXICOLOGY

Relationship Between Serum Uric Acid Levels and Nonalcoholic Fatty Liver Disease in Non-Obese Patients

(2019) Oral et al.   Medicina-Lithuania

MicroRNA 223 3p Negatively Regulates the NLRP3 Inflammasome in Acute and Chronic Liver Injury

(2019) Carolina Jimenez Calvente et al.   MOLECULAR THERAPY

ATP-citrate lyase (ACLY) in lipid metabolism and atherosclerosis: An updated review

(2019) Xiaojun Feng et al.   PROGRESS IN LIPID RESEARCH

Dietary Sugars Alter Hepatic Fatty Acid Oxidation via Transcriptional and Post-translational Modifications of Mitochondrial Proteins

(2019) Samir Softic et al.   Cell Metabolism

Effect of Metabolic Traits on the Risk of Cirrhosis and Hepatocellular Cancer in Non‐alcoholic Fatty Liver Disease

(2019) Fasiha Kanwal et al.   HEPATOLOGY

Dietary Fructose and the Metabolic Syndrome

(2019) Taskinen et al.   Nutrients

Early Hepatic Oxidative Stress and Mitochondrial Changes Following Western Diet in Middle Aged Rats

(2019) Arianna Mazzoli et al.   Nutrients

Dietary fructose and dyslipidemia

(2019) Bettina Hieronimus et al.   CURRENT OPINION IN LIPIDOLOGY

Intestinal Fructose and Glucose Metabolism in Health and Disease

(2019) Beatriz Merino et al.   Nutrients

Anti-NASH Drug Development Hitches a Lift on PPAR Agonism

(2019) Joost Boeckmans et al.   Cells

Pathogenetic, Prognostic, and Therapeutic Role of Fatty Acid Synthase in Human Hepatocellular Carcinoma

(2019) Li Che et al.   Frontiers in Oncology

Intestinal Absorption of Fructose

(2018) Ronaldo P. Ferraris et al.   Annual Review of Nutrition

Nrf2-Keap1 signaling in oxidative and reductive stress

(2018) Ilaria Bellezza et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Aldolase B-Mediated Fructose Metabolism Drives Metabolic Reprogramming of Colon Cancer Liver Metastasis

(2018) Pengcheng Bu et al.   Cell Metabolism

The Small Intestine Converts Dietary Fructose into Glucose and Organic Acids

(2018) Cholsoon Jang et al.   Cell Metabolism

Uric acid and cardiovascular disease

(2018) Gjin Ndrepepa   CLINICA CHIMICA ACTA

The Global Epidemic of the Metabolic Syndrome

(2018) Mohammad G. Saklayen   CURRENT HYPERTENSION REPORTS

Can Serum Uric Acid Lowering Therapy Contribute to the Prevention or Treatment of Nonalcoholic Fatty Liver Disease?

(2018) Paschalis Paschos et al.   Current Vascular Pharmacology

The NOX1 isoform of NADPH oxidase is involved in dysfunction of liver sinusoids in nonalcoholic fatty liver disease

(2018) Misaki Matsumoto et al.   FREE RADICAL BIOLOGY AND MEDICINE

Acetyl-CoA Carboxylase Inhibition Reverses NAFLD and Hepatic Insulin Resistance but Promotes Hypertriglyceridemia in Rodents

(2018) Leigh Goedeke et al.   HEPATOLOGY

Fructose metabolism and metabolic disease

(2018) Sarah A. Hannou et al.   JOURNAL OF CLINICAL INVESTIGATION

Fructose-containing caloric sweeteners as a cause of obesity and metabolic disorders

(2018) Luc Tappy   JOURNAL OF EXPERIMENTAL BIOLOGY

Fructose and sugar: A major mediator of non-alcoholic fatty liver disease

(2018) Thomas Jensen et al.   JOURNAL OF HEPATOLOGY

Fructose liquid and solid formulations differently affect gut integrity, microbiota composition and related liver toxicity: a comparative in vivo study

(2018) Raffaella Mastrocola et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

High-Glucose or -Fructose Diet Cause Changes of the Gut Microbiota and Metabolic Disorders in Mice without Body Weight Change

(2018) Moon Do et al.   Nutrients

Oral administration of fructose exacerbates liver fibrosis and hepatocarcinogenesis via increased intestinal permeability in a rat steatohepatitis model

(2018) Kenichiro Seki et al.   Oncotarget

Polydatin prevents fructose-induced liver inflammation and lipid deposition through increasing miR-200a to regulate Keap1/Nrf2 pathway

(2018) Xiao-Juan Zhao et al.   Redox Biology

Recognizing the Leaky Gut as a Trans-diagnostic Target for Neuroimmune Disorders Using Clinical Chemistry and Molecular Immunology Assays

(2018) Denitsa Simeonova et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

The role of the microbiome in NAFLD and NASH

(2018) Aleksandra A Kolodziejczyk et al.   EMBO Molecular Medicine

Glutathione depleting drugs, antioxidants and intestinal calcium absorption

(2018) Luciana Moine et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Dietary cholesterol promotes steatohepatitis related hepatocellular carcinoma through dysregulated metabolism and calcium signaling

(2018) Jessie Qiaoyi Liang et al.   Nature Communications

Expected changes in obesity after reformulation to reduce added sugars in beverages: A modeling study

(2018) Ana Basto-Abreu et al.   PLOS MEDICINE

Divergent effects of glucose and fructose on hepatic lipogenesis and insulin signaling

(2017) Samir Softic et al.   JOURNAL OF CLINICAL INVESTIGATION

Chronic administration of saturated fats and fructose differently affect SREBP activity resulting in different modulation of Nrf2 and Nlrp3 inflammasome pathways in mice liver

(2017) Debora Nigro et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

The epidemiology of non-alcoholic fatty liver disease

(2017) Stefano Bellentani   LIVER INTERNATIONAL

Fructose-Rich Diet Affects Mitochondrial DNA Damage and Repair in Rats

(2017) Federica Cioffi et al.   Nutrients

Differential Effect of Sucrose and Fructose in Combination with a High Fat Diet on Intestinal Microbiota and Kidney Oxidative Stress

(2017) Adriana Rosas-Villegas et al.   Nutrients

Fructose and NAFLD: The Multifaceted Aspects of  Fructose Metabolism

(2017) Prasanthi Jegatheesan et al.   Nutrients

Fructose Consumption in the Development of Obesity and the Effects of Different Protocols of Physical Exercise on the Hepatic Metabolism

(2017) Rodrigo Pereira et al.   Nutrients

Fructose Intake, Serum Uric Acid, and Cardiometabolic Disorders: A Critical Review

(2017) Cristiana Caliceti et al.   Nutrients

Soluble Uric Acid Activates the NLRP3 Inflammasome

(2017) Tarcio Teodoro Braga et al.   Scientific Reports

Relevance of the NLRP3 Inflammasome in the Pathogenesis of Chronic Liver Disease

(2017) Xiaoqin Wu et al.   Frontiers in Immunology

Fructose: A Dietary Sugar in Crosstalk with Microbiota Contributing to the Development and Progression of Non-Alcoholic Liver Disease

(2017) Jessica Lambertz et al.   Frontiers in Immunology

A critical role for ChREBP-mediated FGF21 secretion in hepatic fructose metabolism

(2017) ffolliott M. Fisher et al.   Molecular Metabolism

Intestinal tract is an important organ for lowering serum uric acid in rats

(2017) Yu Yun et al.   PLoS One

International incidence and mortality trends of liver cancer: a global profile

(2017) Martin C. S. Wong et al.   Scientific Reports

Liver Cancer: Connections with Obesity, Fatty Liver, and Cirrhosis

(2016) Andrea Marengo et al.   Annual Review of Medicine

Role of Dietary Fructose and Hepatic De Novo Lipogenesis in Fatty Liver Disease

(2016) Samir Softic et al.   DIGESTIVE DISEASES AND SCIENCES

Loss of Junctional Adhesion Molecule A Promotes Severe Steatohepatitis in Mice on a Diet High in Saturated Fat, Fructose, and Cholesterol

(2016) Khalidur Rahman et al.   GASTROENTEROLOGY

Effect of uric acid on mitochondrial function and oxidative stress in hepatocytes

(2016) Y. Yang et al.   GENETICS AND MOLECULAR RESEARCH

The independent predictors of non-alcoholic steatohepatitis and its individual histological features.

(2016) Stefano Ballestri et al.   HEPATOLOGY RESEARCH

Uric acid regulates hepatic steatosis and insulin resistance through the NLRP3 inflammasome-dependent mechanism

(2016) Xingyong Wan et al.   JOURNAL OF HEPATOLOGY

Nutritional modulation of endogenous glucagon-like peptide-1 secretion: a review

(2016) Alexandra M. Bodnaruc et al.   Nutrition & Metabolism

The Sweet Path to Metabolic Demise: Fructose and Lipid Synthesis

(2016) Mark A. Herman et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Dietary sugar intake increases liver tumor incidence in female mice

(2016) Marin E. Healy et al.   Scientific Reports

Added Sugars Intake Across the Distribution of US Children and Adult Consumers: 1977-2012

(2016) Elyse S. Powell et al.   Journal of the Academy of Nutrition and Dietetics

Fructose-induced increases in expression of intestinal fructolytic and gluconeogenic genes are regulated by GLUT5 and KHK

(2015) Chirag Patel et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Reactive Oxygen Species-Induced TXNIP Drives Fructose-Mediated Hepatic Inflammation and Lipid Accumulation Through NLRP3 Inflammasome Activation

(2015) Xian Zhang et al.   ANTIOXIDANTS & REDOX SIGNALING

Fructose induces mitochondrial dysfunction and triggers apoptosis in skeletal muscle cells by provoking oxidative stress

(2015) Natasha Jaiswal et al.   APOPTOSIS

High fructose consumption induces DNA methylation at PPARα and CPT1A promoter regions in the rat liver

(2015) Koji Ohashi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Fructose and uric acid in diabetic nephropathy

(2015) Petter Bjornstad et al.   DIABETOLOGIA

Nonalcoholic fatty liver disease: A precursor of the metabolic syndrome

(2015) Amedeo Lonardo et al.   DIGESTIVE AND LIVER DISEASE

Insulin resistance alters hepatic ethanol metabolism: studies in mice and children with non-alcoholic fatty liver disease

(2015) Anna Janina Engstler et al.   GUT

Dietary effects on liver tumor burden in mice treated with the hepatocellular carcinogen diethylnitrosamine

(2015) Marin E. Healy et al.   JOURNAL OF HEPATOLOGY

PPARα gene expression correlates with severity and histological treatment response in patients with non-alcoholic steatohepatitis

(2015) Sven Francque et al.   JOURNAL OF HEPATOLOGY

The story of HCC in NAFLD: from epidemiology, across pathogenesis, to prevention and treatment

(2015) Cristina Margini et al.   LIVER INTERNATIONAL

Nonalcoholic fatty liver disease, metabolic risk factors, and hepatocellular carcinoma: An open question

(2015) Letiția Adela Maria Streba   WORLD JOURNAL OF GASTROENTEROLOGY

MicroRNA Expression Relating to Dietary-Induced Liver Steatosis and NASH

(2015) Aida Zarfeshani et al.   Journal of Clinical Medicine

Liquid fructose downregulates Sirt1 expression and activity and impairs the oxidation of fatty acids in rat and human liver cells

(2014) Alba Rebollo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Monosodium urate crystals trigger Nrf2- and heme oxygenase-1-dependent inflammation in THP-1 cells

(2014) Jhih-Jia Jhang et al.   Cellular & Molecular Immunology

Dietary sugars: their detection by the gut–brain axis and their peripheral and central effects in health and diseases

(2014) Melissa Ochoa et al.   EUROPEAN JOURNAL OF NUTRITION

Global, regional, and national prevalence of overweight and obesity in children and adults during 1980–2013: a systematic analysis for the Global Burden of Disease Study 2013

(2014) Marie Ng et al.   LANCET

Short-term dietary supplementation with fructose accelerates gastric emptying of a fructose but not a glucose solution

(2014) Adora M.W. Yau et al.   NUTRITION

Experimental models of non-alcoholic fatty liver disease in rats

(2014) Otto Kucera   WORLD JOURNAL OF GASTROENTEROLOGY

Non-alcoholic fatty liver disease as a cause and a consequence of metabolic syndrome

(2014) Hannele Yki-Järvinen   Lancet Diabetes & Endocrinology

MiR-214 Promotes the Alcohol-Induced Oxidative Stress via Down-Regulation of Glutathione Reductase and Cytochrome P450 Oxidoreductase in Liver Cells

(2013) Xiaolong Dong et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Role of amino acid transporters in amino acid sensing

(2013) Peter M Taylor   AMERICAN JOURNAL OF CLINICAL NUTRITION

Cross-talk between TLR4-MyD88-NF-κB and SCAP-SREBP2 pathways mediates macrophage foam cell formation

(2013) Lung-Chih Li et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Dietary fructose in nonalcoholic fatty liver disease

(2013) Miriam B. Vos et al.   HEPATOLOGY

NLRP3 inflammasome activation results in hepatocyte pyroptosis, liver inflammation, and fibrosis in mice

(2013) Alexander Wree et al.   HEPATOLOGY

Progression of NAFLD to diabetes mellitus, cardiovascular disease or cirrhosis

(2013) Quentin M. Anstee et al.   Nature Reviews Gastroenterology & Hepatology

microRNA-199a-5p protects hepatocytes from bile acid-induced sustained endoplasmic reticulum stress

(2013) B-H Dai et al.   Cell Death & Disease

Endogenous fructose production and metabolism in the liver contributes to the development of metabolic syndrome

(2013) Miguel A. Lanaspa et al.   Nature Communications

Primary hepatocellular carcinoma and metabolic syndrome: An update

(2013) Rubayat Rahman   World Journal of Gastrointestinal Oncology

Liver cholesterol: is it playing possum in NASH?

(2012) Geoffrey C. Farrell et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Characterization of gut microbiomes in nonalcoholic steatohepatitis (NASH) patients: A connection between endogenous alcohol and NASH

(2012) Lixin Zhu et al.   HEPATOLOGY

The metabolic syndrome of fructose-fed rats: Effects of long-chain polyunsaturated ω3 and ω6 fatty acids. V. Post-mortem findings

(2012) ZOHEIR MELLOUK et al.   Molecular Medicine Reports

Uric Acid Induces Renal Inflammation via Activating Tubular NF-κB Signaling Pathway

(2012) Yang Zhou et al.   PLoS One

Countries that use large amounts of high fructose corn syrup have higher rates of type 2 diabetes

(2012) Z. Kmietowicz   BMJ-British Medical Journal

Thioredoxin Interacting Protein: Redox Dependent and Independent Regulatory Mechanisms

(2011) Oded N. Spindel et al.   ANTIOXIDANTS & REDOX SIGNALING

Protective effects of allopurinol against acute liver damage and cirrhosis induced by carbon tetrachloride: Modulation of NF-κB, cytokine production and oxidative stress

(2011) Liseth R. Aldaba-Muruato et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Toll-like receptors 1–9 are elevated in livers with fructose-induced hepatic steatosis

(2011) Sabine Wagnerberger et al.   BRITISH JOURNAL OF NUTRITION

The role of oxidative stress in non-alcoholic steatohepatitis

(2011) G.H. Koek et al.   CLINICA CHIMICA ACTA

Metabolic syndrome increases the risk of primary liver cancer in the United States: A study in the SEER-medicare database

(2011) Tania M. Welzel et al.   HEPATOLOGY

Recent trend of clinical features in patients with hepatocellular carcinoma

(2011) Yuko Nagaoki et al.   HEPATOLOGY RESEARCH

Reactive oxygen and mechanisms of inflammatory liver injury: Present concepts

(2011) Hartmut Jaeschke   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Intestinal fructose transport and malabsorption in humans

(2010) Hilary F. Jones et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Association between serum uric acid level and chronic liver disease in the United States

(2010) Anita Afzali et al.   HEPATOLOGY

Fructose: Metabolic, Hedonic, and Societal Parallels with Ethanol

(2010) Robert H. Lustig   JOURNAL OF THE AMERICAN DIETETIC ASSOCIATION

The metabolic syndrome

(2010) Robert H Eckel et al.   LANCET

The role of fructose in the pathogenesis of NAFLD and the metabolic syndrome

(2010) Jung Sub Lim et al.   Nature Reviews Gastroenterology & Hepatology

Dietary Sugars Intake and Cardiovascular Health

(2009) Rachel K. Johnson et al.   CIRCULATION

Consuming fructose-sweetened, not glucose-sweetened, beverages increases visceral adiposity and lipids and decreases insulin sensitivity in overweight/obese humans

(2009) Kimber L. Stanhope et al.   JOURNAL OF CLINICAL INVESTIGATION

Ketohexokinase: Expression and Localization of the Principal Fructose-metabolizing Enzyme

(2009) Christine P. Diggle et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Thioredoxin-interacting protein links oxidative stress to inflammasome activation

(2009) Rongbin Zhou et al.   NATURE IMMUNOLOGY

Sugar Absorption in the Intestine: The Role of GLUT2

(2008) George L. Kellett et al.   Annual Review of Nutrition

Oxidative stress induced lipid accumulation via SREBP1c activation in HepG2 cells

(2008) Mika Sekiya et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Fructose and carbonyl metabolites as endogenous toxins

(2008) O. Lee et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Slc2a5 (Glut5) Is Essential for the Absorption of Fructose in the Intestine and Generation of Fructose-induced Hypertension

(2008) Sharon Barone et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Antibiotics protect against fructose-induced hepatic lipid accumulation in mice: Role of endotoxin

(2008) Ina Bergheim et al.   JOURNAL OF HEPATOLOGY

Regulation of glutathione synthesis

(2008) Shelly C. Lu   MOLECULAR ASPECTS OF MEDICINE

Mechanisms of disease: The oxidative stress theory of diabetic neuropathy

(2008) Claudia Figueroa-Romero et al.   REVIEWS IN ENDOCRINE & METABOLIC DISORDERS