Senescent immune cells release grancalcin to promote skeletal aging
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Senescent immune cells release grancalcin to promote skeletal aging
Authors
Keywords
grancalcin, immune cells, skeletal aging, bone marrow mesenchymal stromal cells, plexin-b2 pathway, immunoregulation, bone remodeling, linage fate, senescence
Journal
Cell Metabolism
Volume -, Issue -, Pages -
Publisher
Elsevier BV
Online
2021-09-10
DOI
10.1016/j.cmet.2021.08.009
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Osteoclasts protect bone blood vessels against senescence through the angiogenin/plexin-B2 axis
- (2021) Xiaonan Liu et al. Nature Communications
- Caloric Restriction Reprograms the Single-Cell Transcriptional Landscape of Rattus Norvegicus Aging
- (2020) Shuai Ma et al. CELL
- Reducing Hypothalamic Stem Cell Senescence Protects against Aging-Associated Physiological Decline
- (2020) Yu-Zhong Xiao et al. Cell Metabolism
- Targeted Reduction of Senescent Cell Burden Alleviates Focal Radiotherapy‐Related Bone Loss
- (2020) Abhishek Chandra et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Lipid availability determines fate of skeletal progenitor cells via SOX9
- (2020) Nick van Gastel et al. NATURE
- A Wnt-mediated transformation of the bone marrow stromal cell identity orchestrates skeletal regeneration
- (2020) Yuki Matsushita et al. Nature Communications
- Endothelial progeria induces adipose tissue senescence and impairs insulin sensitivity through senescence associated secretory phenotype
- (2020) Agian Jeffilano Barinda et al. Nature Communications
- The role of cellular senescence in ageing and endocrine disease
- (2020) Sundeep Khosla et al. Nature Reviews Endocrinology
- Role of IL-4 in bone marrow driven dysregulated angiogenesis and age-related macular degeneration
- (2020) Takashi Baba et al. eLife
- Single cell transcriptomics identifies a unique adipose lineage cell population that regulates bone marrow environment
- (2020) Leilei Zhong et al. eLife
- Defined p16High Senescent Cell Types Are Indispensable for Mouse Healthspan
- (2020) Laurent Grosse et al. Cell Metabolism
- Bone marrow adipose tissue is a unique adipose subtype with distinct roles in glucose homeostasis
- (2020) Karla J. Suchacki et al. Nature Communications
- Global phosphoproteomic analysis reveals ARMC10 as an AMPK substrate that regulates mitochondrial dynamics
- (2019) Zhen Chen et al. Nature Communications
- Interleukin-6 Interweaves the Bone Marrow Microenvironment, Bone Loss, and Multiple Myeloma
- (2019) Danielle Harmer et al. Frontiers in Endocrinology
- L1 drives IFN in senescent cells and promotes age-associated inflammation
- (2019) Marco De Cecco et al. NATURE
- Resident Macrophages Cloak Tissue Microlesions to Prevent Neutrophil-Driven Inflammatory Damage
- (2019) Stefan Uderhardt et al. CELL
- Macrophage-lineage TRAP+ cells recruit periosteum-derived cells for periosteal osteogenesis and regeneration
- (2019) Bo Gao et al. JOURNAL OF CLINICAL INVESTIGATION
- Updates on Osteoimmunology: What's New on the Cross-Talk Between Bone and Immune System
- (2019) Marco Ponzetti et al. Frontiers in Endocrinology
- The Bone Marrow Protects and Optimizes Immunological Memory during Dietary Restriction
- (2019) Nicholas Collins et al. CELL
- Five Piconewtons: The Difference between Osteogenic and Adipogenic Fate Choice in Human Mesenchymal Stem Cells
- (2019) Pingping Han et al. ACS Nano
- PLEXIN-B2 promotes the osteogenic differentiation of human bone marrow mesenchymal stem cells via activation of the RhoA signaling pathway
- (2019) Ying Zhang et al. CELLULAR SIGNALLING
- Analysis of Genetically Diverse Macrophages Reveals Local and Domain-wide Mechanisms that Control Transcription Factor Binding and Function
- (2018) Verena M. Link et al. CELL
- PGC-1α Controls Skeletal Stem Cell Fate and Bone-Fat Balance in Osteoporosis and Skeletal Aging by Inducing TAZ
- (2018) Bo Yu et al. Cell Stem Cell
- Functional Gut Microbiota Remodeling Contributes to the Caloric Restriction-Induced Metabolic Improvements
- (2018) Salvatore Fabbiano et al. Cell Metabolism
- Deletion of the immunoglobulin heavy chain 3′ regulatory region super-enhancer affects somatic hypermutation in B1 B cells
- (2018) Issaoui Hussein et al. Cellular & Molecular Immunology
- Long noncoding RNA Bmncr regulates mesenchymal stem cell fate during skeletal aging
- (2018) Chang-Jun Li et al. JOURNAL OF CLINICAL INVESTIGATION
- Tumor immunoevasion via acidosis-dependent induction of regulatory tumor-associated macrophages
- (2018) Toszka Bohn et al. NATURE IMMUNOLOGY
- The PRIDE database and related tools and resources in 2019: improving support for quantification data
- (2018) Yasset Perez-Riverol et al. NUCLEIC ACIDS RESEARCH
- Macrophage cells secrete factors including LRP1 that orchestrate the rejuvenation of bone repair in mice
- (2018) Linda Vi et al. Nature Communications
- B cells inhibit bone formation in rheumatoid arthritis by suppressing osteoblast differentiation
- (2018) Wen Sun et al. Nature Communications
- Bone Mass Is Compromised by the Chemotherapeutic Trabectedin in Association With Effects on Osteoblasts and Macrophage Efferocytosis
- (2017) Benjamin P Sinder et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Targeting cellular senescence prevents age-related bone loss in mice
- (2017) Joshua N Farr et al. NATURE MEDICINE
- Grancalcin (GCA) modulates Toll-like receptor 9 (TLR9) mediated signaling through its direct interaction with TLR9
- (2016) Tae Whan Kim et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Macrophages in Tissue Repair, Regeneration, and Fibrosis
- (2016) Thomas A. Wynn et al. IMMUNITY
- Modulation of Osteoblastic Cell Efferocytosis by Bone Marrow Macrophages
- (2016) Megan N. Michalski et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- RhoA determines lineage fate of mesenchymal stem cells by modulating CTGF–VEGF complex in extracellular matrix
- (2016) Changjun Li et al. Nature Communications
- SnapShot: Osteoimmunology
- (2015) Hiroshi Takayanagi Cell Metabolism
- Macrophages Promote Osteoblastic Differentiation In Vivo: Implications in Fracture Repair and Bone Homeostasis
- (2015) Linda Vi et al. JOURNAL OF BONE AND MINERAL RESEARCH
- MicroRNA-188 regulates age-related switch between osteoblast and adipocyte differentiation
- (2015) Chang-Jun Li et al. JOURNAL OF CLINICAL INVESTIGATION
- Neutrophil ageing is regulated by the microbiome
- (2015) Dachuan Zhang et al. NATURE
- Spatial reconstruction of single-cell gene expression data
- (2015) Rahul Satija et al. NATURE BIOTECHNOLOGY
- Comparative analysis of the efficiency and specificity of myeloid-Cre deleting strains using ROSA-EYFP reporter mice
- (2014) Clare L. Abram et al. JOURNAL OF IMMUNOLOGICAL METHODS
- Osteal Tissue Macrophages Are Intercalated throughout Human and Mouse Bone Lining Tissues and Regulate Osteoblast Function In Vitro and In Vivo
- (2014) M. K. Chang et al. JOURNAL OF IMMUNOLOGY
- PDGF-BB secreted by preosteoclasts induces angiogenesis during coupling with osteogenesis
- (2014) Hui Xie et al. NATURE MEDICINE
- Disruption of LRP6 in osteoblasts blunts the bone anabolic activity of PTH
- (2013) Changjun Li et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Macrophage biology in development, homeostasis and disease
- (2013) Thomas A. Wynn et al. NATURE
- clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters
- (2012) Guangchuang Yu et al. OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY
- Induction of Osteogenesis in Mesenchymal Stem Cells by Activated Monocytes/Macrophages Depends on Oncostatin M Signaling
- (2012) Pierre Guihard et al. STEM CELLS
- Osteal macrophages promote in vivo intramembranous bone healing in a mouse tibial injury model
- (2011) Kylie A Alexander et al. JOURNAL OF BONE AND MINERAL RESEARCH
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search