Osteoclasts protect bone blood vessels against senescence through the angiogenin/plexin-B2 axis

Glucocorticoids disrupt skeletal angiogenesis through transrepression of NF‐κB‐mediated preosteoclast Pdgfb transcription in young mice

(2020) Yi Peng et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Myeloid cells protect intestinal epithelial barrier integrity through the angiogenin/plexin‐B2 axis

(2020) Rongpan Bai et al.   EMBO JOURNAL

Cellular Senescence and Radiation-induced Pulmonary Fibrosis

(2019) Yonghan He et al.   Translational Research

Cells exhibiting strong p16INK4a promoter activation in vivo display features of senescence

(2019) Jie-Yu Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ribosomal protein RPL22/eL22 regulates the cell cycle by acting as an inhibitor of the CDK4-cyclin D complex

(2019) Neylen Del Toro et al.   CELL CYCLE

Endothelial proteolytic activity and interaction with non-resorbing osteoclasts mediate bone elongation

(2019) Sara G. Romeo et al.   NATURE CELL BIOLOGY

Inhibition of the 60S ribosome biogenesis GTPase LSG1 causes endoplasmic reticular disruption and cellular senescence

(2019) Asimina Pantazi et al.   AGING CELL

The innate immune sensor Toll-like receptor 2 controls the senescence-associated secretory phenotype

(2019) Priya Hari et al.   Science Advances

Preservation of type H vessels and osteoblasts by enhanced preosteoclast platelet-derived growth factor type BB attenuates glucocorticoid-induced osteoporosis in growing mice

(2018) Ping Yang et al.   BONE

Angiogenin/Ribonuclease 5 Is an EGFR Ligand and a Serum Biomarker for Erlotinib Sensitivity in Pancreatic Cancer

(2018) Ying-Nai Wang et al.   CANCER CELL

Glucocorticoids and bone: consequences of endogenous and exogenous excess and replacement therapy

(2018) Rowan S Hardy et al.   ENDOCRINE REVIEWS

Long-term effects of glucocorticoids on function, quality of life, and survival in patients with Duchenne muscular dystrophy: a prospective cohort study

(2018) Craig M McDonald et al.   LANCET

Senescence-associated ribosome biogenesis defects contributes to cell cycle arrest through the Rb pathway

(2018) Frédéric Lessard et al.   NATURE CELL BIOLOGY

Pleiotropic activity of systemically delivered angiogenin in the SOD1 G93A mouse model

(2018) Martin Crivello et al.   NEUROPHARMACOLOGY

Anabolic Therapy for the Treatment of Osteoporosis in Childhood

(2018) Leanne M. Ward et al.   Current Osteoporosis Reports

Glucocorticoid treatment in juvenile idiopathic arthritis

(2018) Ezgi Deniz Batu   RHEUMATOLOGY INTERNATIONAL

The Pathophysiological Sequence of Glucocorticoid-Induced Osteonecrosis of the Femoral Head in Male Mice

(2017) Robert S Weinstein et al.   ENDOCRINOLOGY

Animal models to explore the effects of glucocorticoids on skeletal growth and structure

(2017) Claire L Wood et al.   JOURNAL OF ENDOCRINOLOGY

Senescent cells: an emerging target for diseases of ageing

(2017) Bennett G. Childs et al.   NATURE REVIEWS DRUG DISCOVERY

Spatial and Temporal Control of Senescence

(2017) Yoko Ito et al.   TRENDS IN CELL BIOLOGY

A topically-sprayable, activatable fluorescent and retaining probe, SPiDER-βGal for detecting cancer: Advantages of anchoring to cellular proteins after activation

(2017) Yuko Nakamura et al.   Oncotarget

Oral glucocorticoid use and osteonecrosis in children and adults with chronic inflammatory diseases: a population-based cohort study

(2017) Daniel B Horton et al.   BMJ Open

Association Between Linear Growth and Bone Accrual in a Diverse Cohort of Children and Adolescents

(2017) Shana E. McCormack et al.   JAMA Pediatrics

Single Stem Cell Imaging and Analysis Reveals Telomere Length Differences in Diseased Human and Mouse Skeletal Muscles

(2017) Elisia D. Tichy et al.   Stem Cell Reports

Angiogenin Promotes Hematopoietic Regeneration by Dichotomously Regulating Quiescence of Stem and Progenitor Cells

(2016) Kevin A. Goncalves et al.   CELL

Proximity-Based Differential Single-Cell Analysis of the Niche to Identify Stem/Progenitor Cell Regulators

(2016) Lev Silberstein et al.   Cell Stem Cell

Blood vessel formation and function in bone

(2016) Kishor K. Sivaraj et al.   DEVELOPMENT

The safety of treatment options for pediatric Crohn’s disease

(2016) Victoria Grossi et al.   Expert Opinion On Drug Safety

Protection From Glucocorticoid-Induced Osteoporosis by Anti-Catabolic Signaling in the Absence of Sost/Sclerostin

(2016) Amy Y Sato et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Molecular basis for the autonomous promotion of cell proliferation by angiogenin

(2016) Trish T. Hoang et al.   NUCLEIC ACIDS RESEARCH

The National Osteoporosis Foundation’s position statement on peak bone mass development and lifestyle factors: a systematic review and implementation recommendations

(2016) C. M. Weaver et al.   OSTEOPOROSIS INTERNATIONAL

Molecular Actions of Glucocorticoids in Cartilage and Bone During Health, Disease, and Steroid Therapy

(2016) Kerstin Hartmann et al.   PHYSIOLOGICAL REVIEWS

RNA biology of angiogenin: Current state and perspectives

(2016) Shawn M. Lyons et al.   RNA Biology

Angiogenin is upregulated during the alloreactive immune response and has no effect on the T-cell expansion phase, whereas it affects the contraction phase by inhibiting CD4+ T-cell apoptosis

(2016) Theodoros Eleftheriadis et al.   Experimental and Therapeutic Medicine

Blood flow controls bone vascular function and osteogenesis

(2016) Saravana K. Ramasamy et al.   Nature Communications

Cytokines shape chemotherapy-induced and ‘bystander' senescence

(2016) Zdenek Hodny et al.   Aging-US

IL1- and TGFβ-Nox4 signaling, oxidative stress and DNA damage response are shared features of replicative, oncogene-induced, and drug-induced paracrine ‘Bystander senescence’

(2016) Sona Hubackova et al.   Aging-US

Making sense of hematopoietic stem cell niches

(2015) P. E. Boulais et al.   BLOOD

Dexamethasone in osteogenic medium strongly induces adipocyte differentiation of mouse bone marrow stromal cells and increases osteoblast differentiation

(2015) Olfa Ghali et al.   BMC CELL BIOLOGY

Bone development

(2015) Agnes D. Berendsen et al.   BONE

Prevention of glucocorticoid induced-apoptosis of osteoblasts and osteocytes by protecting against endoplasmic reticulum (ER) stress in vitro and in vivo in female mice

(2015) Amy Y. Sato et al.   BONE

Deep imaging of bone marrow shows non-dividing stem cells are mainly perisinusoidal

(2015) Melih Acar et al.   NATURE

Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice

(2015) Jianhui Chang et al.   NATURE MEDICINE

Glucocorticoid pharmacogenetics in pediatric idiopathic nephrotic syndrome

(2015) Eva Cuzzoni et al.   PHARMACOGENOMICS

Perturbation of Ribosome Biogenesis Drives Cells into Senescence through 5S RNP-Mediated p53 Activation

(2015) Kazuho Nishimura et al.   Cell Reports

Disruption of p16 and Activation of Kras in Pancreas Increase Ductal Adenocarcinoma Formation and Metastasis in vivo

(2015) Wanglong Qiu et al.   Oncotarget

Angiogenin-Cleaved tRNA Halves Interact with Cytochrome c, Protecting Cells from Apoptosis during Osmotic Stress

(2014) M. Saikia et al.   MOLECULAR AND CELLULAR BIOLOGY

The bone marrow niche for haematopoietic stem cells

(2014) Sean J. Morrison et al.   NATURE

Coupling of angiogenesis and osteogenesis by a specific vessel subtype in bone

(2014) Anjali P. Kusumbe et al.   NATURE

Endothelial Notch activity promotes angiogenesis and osteogenesis in bone

(2014) Saravana K. Ramasamy et al.   NATURE

PDGF-BB secreted by preosteoclasts induces angiogenesis during coupling with osteogenesis

(2014) Hui Xie et al.   NATURE MEDICINE

Cellular senescence: from physiology to pathology

(2014) Daniel Muñoz-Espín et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A systematic review and meta-analysis of glucocorticoid-induced osteoporosis in children

(2014) Karen E. Hansen et al.   SEMINARS IN ARTHRITIS AND RHEUMATISM

Glucocorticoids and bone: local effects and systemic implications

(2014) Holger Henneicke et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

VE-Cadherin and Endothelial Adherens Junctions: Active Guardians of Vascular Integrity

(2013) Monica Giannotta et al.   DEVELOPMENTAL CELL

Disruption of LRP6 in osteoblasts blunts the bone anabolic activity of PTH

(2013) Changjun Li et al.   JOURNAL OF BONE AND MINERAL RESEARCH

p53-dependent release of Alarmin HMGB1 is a central mediator of senescent phenotypes

(2013) Albert R. Davalos et al.   JOURNAL OF CELL BIOLOGY

Arteriolar niches maintain haematopoietic stem cell quiescence

(2013) Yuya Kunisaki et al.   NATURE

Glucocorticoids and the regulation of growth hormone secretion

(2013) Gherardo Mazziotti et al.   Nature Reviews Endocrinology

Dexamethasone shifts bone marrow stromal cells from osteoblasts to adipocytes by C/EBPalpha promoter methylation

(2013) J Li et al.   Cell Death & Disease

A senescent cell bystander effect: senescence-induced senescence

(2012) Glyn Nelson et al.   AGING CELL

Lamin B1 loss is a senescence-associated biomarker

(2012) Adam Freund et al.   MOLECULAR BIOLOGY OF THE CELL

Angiogenin functionally interacts with p53 and regulates p53-mediated apoptosis and cell survival

(2012) S Sadagopan et al.   ONCOGENE

Glucocorticoid Receptor and Sequential P53 Activation by Dexamethasone Mediates Apoptosis and Cell Cycle Arrest of Osteoblastic MC3T3-E1 Cells

(2012) Hui Li et al.   PLoS One

Skeletal receptors for steroid-family regulating glycoprotein hormones

(2011) Harry C. Blair et al.   Annals of the New York Academy of Sciences

Glucocorticoid dose determines osteocyte cell fate

(2011) Junjing Jia et al.   FASEB JOURNAL

Emerging role of angiogenin in stress response and cell survival under adverse conditions

(2011) Shuping Li et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Glucocorticoid-Induced Bone Disease

(2011) Robert S. Weinstein   NEW ENGLAND JOURNAL OF MEDICINE

Glucocorticoids Suppress Bone Formation by Attenuating Osteoblast Differentiation via the Monomeric Glucocorticoid Receptor

(2010) Alexander Rauch et al.   Cell Metabolism

Glucocorticoid-induced autophagy in osteocytes

(2010) Xuechun Xia et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Glucocorticoids, osteocytes, and skeletal fragility: The role of bone vascularity

(2009) Robert S. Weinstein   BONE

Maximizing bone mineral mass gain during growth for the prevention of fractures in the adolescents and the elderly

(2009) René Rizzoli et al.   BONE

Angiogenin-Stimulated rRNA Transcription Is Essential for Initiation and Survival of AKT-Induced Prostate Intraepithelial Neoplasia

(2009) S. Ibaragi et al.   MOLECULAR CANCER RESEARCH

TGF-β1–induced migration of bone mesenchymal stem cells couples bone resorption with formation

(2009) Yi Tang et al.   NATURE MEDICINE

Glucocorticoid excess in mice results in early activation of osteoclastogenesis and adipogenesis and prolonged suppression of osteogenesis: A longitudinal study of gene expression in bone tissue from glucocorticoid-treated mice

(2008) Wei Yao et al.   ARTHRITIS AND RHEUMATISM

Growth Hormone, Insulin-Like Growth Factors, and the Skeleton

(2008) Andrea Giustina et al.   ENDOCRINE REVIEWS

Parathyroid hormone signaling through low-density lipoprotein-related protein 6

(2008) M. Wan et al.   GENES & DEVELOPMENT

Control of Motoneuron Survival by Angiogenin

(2008) D. Kieran et al.   JOURNAL OF NEUROSCIENCE

Exploring RNA transcription and turnover in vivo by using click chemistry

(2008) C. Y. Jao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA