Long noncoding RNA Bmncr regulates mesenchymal stem cell fate during skeletal aging

Polycystin-1 interacts with TAZ to stimulate osteoblastogenesis and inhibit adipogenesis

(2017) Zhousheng Xiao et al.   JOURNAL OF CLINICAL INVESTIGATION

FOXP1 controls mesenchymal stem cell commitment and senescence during skeletal aging

(2017) Hanjun Li et al.   JOURNAL OF CLINICAL INVESTIGATION

Targeting cellular senescence prevents age-related bone loss in mice

(2017) Joshua N Farr et al.   NATURE MEDICINE

Leptin Receptor Promotes Adipogenesis and Reduces Osteogenesis by Regulating Mesenchymal Stromal Cells in Adult Bone Marrow

(2016) Rui Yue et al.   Cell Stem Cell

Reciprocal stabilization of ABL and TAZ regulates osteoblastogenesis through transcription factor RUNX2

(2016) Yoshinori Matsumoto et al.   JOURNAL OF CLINICAL INVESTIGATION

Yap/Taz transcriptional activity in endothelial cells promotes intramembranous ossification via the BMP pathway

(2016) Mami Uemura et al.   Scientific Reports

MicroRNA-188 regulates age-related switch between osteoblast and adipocyte differentiation

(2015) Chang-Jun Li et al.   JOURNAL OF CLINICAL INVESTIGATION

Canonical Wnt signalling activates TAZ through PP1A during osteogenic differentiation

(2014) M R Byun et al.   CELL DEATH AND DIFFERENTIATION

Leptin-Receptor-Expressing Mesenchymal Stromal Cells Represent the Main Source of Bone Formed by Adult Bone Marrow

(2014) Bo O. Zhou et al.   Cell Stem Cell

Cells Isolated from Human Periapical Cysts Express Mesenchymal Stem Cell-like Properties

(2014) Massimo Marrelli et al.   International Journal of Biological Sciences

Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants

(2014) Lorenzo Pasquali et al.   NATURE GENETICS

PDGF-BB secreted by preosteoclasts induces angiogenesis during coupling with osteogenesis

(2014) Hui Xie et al.   NATURE MEDICINE

Osteoblast-Specific Deletion of Pkd2 Leads to Low-Turnover Osteopenia and Reduced Bone Marrow Adiposity

(2014) Zhousheng Xiao et al.   PLoS One

Braveheart, a Long Noncoding RNA Required for Cardiovascular Lineage Commitment

(2013) Carla A. Klattenhoff et al.   CELL

Disruption of LRP6 in osteoblasts blunts the bone anabolic activity of PTH

(2013) Changjun Li et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Long noncoding RNAs regulate adipogenesis

(2013) Lei Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RNA-Guided Human Genome Engineering via Cas9

(2013) P. Mali et al.   SCIENCE

Multiplex Genome Engineering Using CRISPR/Cas Systems

(2013) L. Cong et al.   SCIENCE

Mesenchymal progenitors residing close to the bone surface are functionally distinct from those in the central bone marrow

(2012) Valerie A. Siclari et al.   BONE

Human β Cell Transcriptome Analysis Uncovers lncRNAs That Are Tissue-Specific, Dynamically Regulated, and Abnormally Expressed in Type 2 Diabetes

(2012) Ignasi Morán et al.   Cell Metabolism

Long Noncoding RNA, Polycomb, and the Ghosts Haunting INK4b-ARF-INK4a Expression

(2011) F. Aguilo et al.   CANCER RESEARCH

ncRNA- and Pc2 Methylation-Dependent Gene Relocation between Nuclear Structures Mediates Gene Activation Programs

(2011) Liuqing Yang et al.   CELL

Human long non-coding RNAs promote pluripotency and neuronal differentiation by association with chromatin modifiers and transcription factors

(2011) Shi-Yan Ng et al.   EMBO JOURNAL

lincRNAs act in the circuitry controlling pluripotency and differentiation

(2011) Mitchell Guttman et al.   NATURE

An evolutionarily conserved three-dimensional structure in the vertebrate Irx clusters facilitates enhancer sharing and coregulation

(2011) Juan J. Tena et al.   Nature Communications

Ab initio reconstruction of cell type–specific transcriptomes in mouse reveals the conserved multi-exonic structure of lincRNAs

(2010) Mitchell Guttman et al.   NATURE BIOTECHNOLOGY

Long Noncoding RNA as Modular Scaffold of Histone Modification Complexes

(2010) M.-C. Tsai et al.   SCIENCE

Coexistence of Quiescent and Active Adult Stem Cells in Mammals

(2010) L. Li et al.   SCIENCE

Control of Stem Cell Fate by Physical Interactions with the Extracellular Matrix

(2009) Farshid Guilak et al.   Cell Stem Cell

Conditional Disruption ofPkd1in Osteoblasts Results in Osteopenia Due to Direct Impairment of Bone Formation

(2009) Zhousheng Xiao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A novel microRNA targeting HDAC5 regulates osteoblast differentiation in mice and contributes to primary osteoporosis in humans

(2009) Hui Li et al.   JOURNAL OF CLINICAL INVESTIGATION

Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals

(2009) Mitchell Guttman et al.   NATURE

TGF-β1–induced migration of bone mesenchymal stem cells couples bone resorption with formation

(2009) Yi Tang et al.   NATURE MEDICINE

Growth Factors, Matrices, and Forces Combine and Control Stem Cells

(2009) D. E. Discher et al.   SCIENCE

Stem Cells and Niches: Mechanisms That Promote Stem Cell Maintenance throughout Life

(2008) Sean J. Morrison et al.   CELL

Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor

(2008) Jean-Philippe Coppé et al.   PLOS BIOLOGY