- Home
- Publications
- Publication Search
- Publication Details
Title
Druggability of lipid metabolism modulation against renal fibrosis
Authors
Keywords
-
Journal
ACTA PHARMACOLOGICA SINICA
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2021-05-14
DOI
10.1038/s41401-021-00660-1
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Renal tubule Cpt1a overexpression protects from kidney fibrosis by restoring mitochondrial homeostasis
- (2021) Verónica Miguel et al. JOURNAL OF CLINICAL INVESTIGATION
- circACTR2: A Novel Mechanism Regulating High Glucose-Induced Fibrosis in Renal Tubular Cells via Pyroptosis
- (2020) Si Wen et al. BIOLOGICAL & PHARMACEUTICAL BULLETIN
- CPT1A-mediated Fat Oxidation, Mechanisms, and Therapeutic Potential
- (2020) Isabel R Schlaepfer et al. ENDOCRINOLOGY
- Theranostic combinatorial drug-loaded coated cubosomes for enhanced targeting and efficacy against cancer cells
- (2020) Leilei Zhang et al. Cell Death & Disease
- New Insights on the Role of Lipid Metabolism in the Metabolic Reprogramming of Macrophages
- (2020) Ana Batista-Gonzalez et al. Frontiers in Immunology
- Nanoparticle-Based Delivery of Tumor Suppressor microRNA for Cancer Therapy
- (2020) Clodagh P. O’Neill et al. Cells
- Circular RNA in renal diseases
- (2020) Juan Jin et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Recent Insights Into SREBP as a Direct Mediator of Kidney Fibrosis via Lipid-Independent Pathways
- (2020) Debra Dorotea et al. Frontiers in Pharmacology
- Myofibroblasts and Fibrosis
- (2020) Andrew A. Gibb et al. CIRCULATION RESEARCH
- Long non-coding RNAs: from disease code to drug role
- (2020) Yuanyuan Chen et al. Acta Pharmaceutica Sinica B
- Circular RNAs: Rising stars in lipid metabolism and lipid disorders
- (2020) Guangli Yu et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Application of PCSK9 Inhibitors in Practice
- (2019) Tina M. Kaufman et al. CIRCULATION RESEARCH
- ATF6α downregulation of PPARα promotes lipotoxicity-induced tubulointerstitial fibrosis
- (2019) Tzu-Ming Jao et al. KIDNEY INTERNATIONAL
- Exosomes: biogenesis, biologic function and clinical potential
- (2019) Yuan Zhang et al. Cell and Bioscience
- Fenofibrate Improved Interstitial Fibrosis of Renal Allograft through Inhibited Epithelial-Mesenchymal Transition Induced by Oxidative Stress
- (2019) Yishu Wang et al. Oxidative Medicine and Cellular Longevity
- MicroRNA-214 promotes chronic kidney disease by disrupting mitochondrial oxidative phosphorylation
- (2019) Mi Bai et al. KIDNEY INTERNATIONAL
- Metabolic Reprogramming as a Driver of Fibroblast Activation in Pulmonary Fibrosis
- (2019) Rachel Para et al. AMERICAN JOURNAL OF THE MEDICAL SCIENCES
- Advanced oxidation protein products promote lipotoxicity and tubulointerstitial fibrosis via CD36/β-catenin pathway in diabetic nephropathy
- (2019) Xiao Li et al. ANTIOXIDANTS & REDOX SIGNALING
- Activated NF-κB/Nrf2 and Wnt/β-catenin pathways are associated with lipid metabolism in CKD patients with microalbuminuria and macroalbuminuria
- (2019) Ya-Long Feng et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- An in Vivo miRNA Delivery System for Restoring Infarcted Myocardium
- (2019) Huaxiao Yang et al. ACS Nano
- PGC‐1α, a potential therapeutic target against kidney aging
- (2019) Gayoung Lee et al. AGING CELL
- Efficacy and Safety of Evolocumab in Chronic Kidney Disease in the FOURIER Trial
- (2019) David M. Charytan et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Emerging strategies to disrupt the central TGF-β axis in kidney fibrosis
- (2019) Michael Rauchman et al. Translational Research
- The PPARγ agonist pioglitazone prevents TGF-β induced renal fibrosis by repressing EGR-1 and STAT3
- (2019) Ágnes Németh et al. BMC Nephrology
- Exosomes Engineered to Express a Cardiomyocyte Binding Peptide Demonstrate Improved Cardiac Retention in Vivo
- (2019) Kyle I. Mentkowski et al. Scientific Reports
- Targeting metabolic dysregulation for fibrosis therapy
- (2019) Xiao Zhao et al. NATURE REVIEWS DRUG DISCOVERY
- Berberine protects against diabetic kidney disease via promoting PGC‐1α‐regulated mitochondrial energy homeostasis
- (2019) Xin Qin et al. BRITISH JOURNAL OF PHARMACOLOGY
- MiR‐9‐5p protects from kidney fibrosis by metabolic reprogramming
- (2019) Marta Fierro‐Fernández et al. FASEB JOURNAL
- First‐in‐class fatty acid synthase inhibitor TVB‐2640 reduces hepatic de novo lipogenesis in males with metabolic abnormalities
- (2019) Majid M. Syed‐Abdul et al. HEPATOLOGY
- MicroRNA delivery through nanoparticles
- (2019) Sharon Wei Ling Lee et al. JOURNAL OF CONTROLLED RELEASE
- Functional heterogeneity of resident fibroblasts in the kidney
- (2019) Yuki SATO et al. PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES
- MiR-9-5p Inhibits Glioblastoma Cells Proliferation Through Directly Targeting FOXP2 (Forkhead Box P2)
- (2019) Hongbo Zhang et al. Frontiers in Oncology
- Mitochondrial carnitine palmitoyltransferase 2 is involved in Nε-(carboxymethyl)-lysine-mediated diabetic nephropathy
- (2019) Jangho Lee et al. PHARMACOLOGICAL RESEARCH
- Targeting renal fibrosis: Mechanisms and drug delivery systems
- (2018) Madalina V. Nastase et al. ADVANCED DRUG DELIVERY REVIEWS
- MicroRNAs in the pathogenesis and treatment of progressive liver injury in NAFLD and liver fibrosis
- (2018) Qiaozhu Su et al. ADVANCED DRUG DELIVERY REVIEWS
- Mechanisms of Renal Fibrosis
- (2018) Benjamin D. Humphreys Annual Review of Physiology
- TGF-β-mediated upregulation of Sox9 in fibroblast promotes renal fibrosis
- (2018) Huanan Li et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Central role of dysregulation of TGF-β/Smad in CKD progression and potential targets of its treatment
- (2018) Lin Chen et al. BIOMEDICINE & PHARMACOTHERAPY
- Identification and Characterization of CircRNAs of Two Pig Breeds as a New Biomarker in Metabolism-Related Diseases
- (2018) Ai Li et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Antifibrotic role of PGC-1α-siRNA against TGF-β1-induced renal interstitial fibrosis
- (2018) Jue-Long Wang et al. EXPERIMENTAL CELL RESEARCH
- Impairment of PPARαand the Fatty Acid Oxidation Pathway Aggravates Renal Fibrosis during Aging
- (2018) Ki Wung Chung et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Targeting TGF-β signaling for the treatment of fibrosis
- (2018) Andrea Hermina Györfi et al. MATRIX BIOLOGY
- Cellular and molecular mechanisms of kidney fibrosis
- (2018) Sonja Djudjaj et al. MOLECULAR ASPECTS OF MEDICINE
- TGF-β Mediates Renal Fibrosis via the Smad3-Erbb4-IR Long Noncoding RNA Axis
- (2018) Min Feng et al. MOLECULAR THERAPY
- Downregulation of SREBP inhibits tumor growth and initiation by altering cellular metabolism in colon cancer
- (2018) Yang-An Wen et al. Cell Death & Disease
- Adipocyte-Derived Exosomal MiR-27a Induces Insulin Resistance in Skeletal Muscle Through Repression of PPARγ
- (2018) Yang Yu et al. Theranostics
- An Integrated Lipidomics and Phenotype Study Reveals Protective Effect and Biochemical Mechanism of Traditionally Used Alisma orientale Juzepzuk in Chronic Kidney Disease
- (2018) Fang Dou et al. Frontiers in Pharmacology
- Jagged1/Notch2 controls kidney fibrosis via Tfam-mediated metabolic reprogramming
- (2018) Shizheng Huang et al. PLOS BIOLOGY
- lncRNA ZEB1-AS1 Was Suppressed by p53 for Renal Fibrosis in Diabetic Nephropathy
- (2018) Juan Wang et al. Molecular Therapy-Nucleic Acids
- Role of miR-9-5p in preventing peripheral neuropathy in patients with rheumatoid arthritis by targeting REST/miR-132 pathway
- (2018) Zunzhong Li et al. IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL
- Evolocumab para el tratamiento de la hipercolesterolemia familiar heterocigota en enfermedad renal crónica avanzada y diálisis
- (2018) Silvia González Sanchidrián et al. NEFROLOGIA
- Obesity-associated exosomal miRNAs modulate glucose and lipid metabolism in mice
- (2018) Carlos Castaño et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Long noncoding RNA lnc-TSI inhibits renal fibrogenesis by negatively regulating the TGF-β/Smad3 pathway
- (2018) Peng Wang et al. Science Translational Medicine
- Renal tubular epithelial cells: the neglected mediator of tubulointerstitial fibrosis after injury
- (2018) Ruochen Qi et al. Cell Death & Disease
- Epigenetic silencing of ZNF132 mediated by methylation-sensitive Sp1 binding promotes cancer progression in esophageal squamous cell carcinoma
- (2018) Dong Jiang et al. Cell Death & Disease
- Complement C3 Produced by Macrophages Promotes Renal Fibrosis via IL-17A Secretion
- (2018) Yanyan Liu et al. Frontiers in Immunology
- PPARγ maintains the metabolic heterogeneity and homeostasis of renal tubules
- (2018) Zhongshi Lyu et al. EBioMedicine
- Novel Biomarkers in the Diagnosis of Chronic Kidney Disease and the Prediction of Its Outcome
- (2017) Jacek Rysz et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- PGC-1αProtects from Notch-Induced Kidney Fibrosis Development
- (2017) Seung Hyeok Han et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Kidney Proximal Tubule Lipoapoptosis Is Regulated by Fatty Acid Transporter-2 (FATP2)
- (2017) Shenaz Khan et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Macrophage-to-Myofibroblast Transition Contributes to Interstitial Fibrosis in Chronic Renal Allograft Injury
- (2017) Ying-Ying Wang et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- A new CTGF target in renal fibrosis
- (2017) John R. Montford et al. KIDNEY INTERNATIONAL
- CD36 in chronic kidney disease: novel insights and therapeutic opportunities
- (2017) Xiaochun Yang et al. Nature Reviews Nephrology
- Complement C5a inhibition moderates lipid metabolism and reduces tubulointerstitial fibrosis in diabetic nephropathy
- (2017) Wai Han Yiu et al. NEPHROLOGY DIALYSIS TRANSPLANTATION
- The link between phenotype and fatty acid metabolism in advanced chronic kidney disease
- (2017) Dan-Qian Chen et al. NEPHROLOGY DIALYSIS TRANSPLANTATION
- Targeting TGF-β Mediated SMAD Signaling for the Prevention of Fibrosis
- (2017) Kelly L. Walton et al. Frontiers in Pharmacology
- Progression of Tubulointerstitial Fibrosis and the Chronic Kidney Disease Phenotype – Role of Risk Factors and Epigenetics
- (2017) Timothy D. Hewitson et al. Frontiers in Pharmacology
- Long noncoding RNA Tug1 regulates mitochondrial bioenergetics in diabetic nephropathy
- (2016) Jianyin Long et al. JOURNAL OF CLINICAL INVESTIGATION
- Peroxisome proliferator-activated receptor-γ agonist pioglitazone fails to attenuate renal fibrosis caused by unilateral ureteral obstruction in mice
- (2016) Ying Zhang et al. Journal of Huazhong University of Science and Technology-Medical Sciences
- Lipotoxicity as a trigger factor of renal disease
- (2016) Adriana Izquierdo-Lahuerta et al. JOURNAL OF NEPHROLOGY
- Antagonism of scavenger receptor CD36 by 5A peptide prevents chronic kidney disease progression in mice independent of blood pressure regulation
- (2016) Ana Carolina P. Souza et al. KIDNEY INTERNATIONAL
- A novel long non-coding RNA CYP4B1-PS1-001 regulates proliferation and fibrosis in diabetic nephropathy
- (2016) Min Wang et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Developmental signalling pathways in renal fibrosis: the roles of Notch, Wnt and Hedgehog
- (2016) Maria Edeling et al. Nature Reviews Nephrology
- TGF-β: the master regulator of fibrosis
- (2016) Xiao-ming Meng et al. Nature Reviews Nephrology
- MicroRNA-27a promotes renal tubulointerstitial fibrosis via suppressing PPARγ pathway in diabetic nephropathy
- (2016) Xiaoyan Hou et al. Oncotarget
- Metabolomics insights into activated redox signaling and lipid metabolism dysfunction in chronic kidney disease progression
- (2016) Hua Chen et al. Redox Biology
- Roles, Functions, and Mechanisms of Long Non-coding RNAs in Cancer
- (2016) Yiwen Fang et al. GENOMICS PROTEOMICS & BIOINFORMATICS
- The Macrophage Phagocytic Receptor CD36 Promotes Fibrogenic Pathways on Removal of Apoptotic Cells during Chronic Kidney Injury
- (2015) Subramaniam Pennathur et al. AMERICAN JOURNAL OF PATHOLOGY
- Glycolytic Reprogramming in Myofibroblast Differentiation and Lung Fibrosis
- (2015) Na Xie et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- CD36 is involved in high glucose-induced epithelial to mesenchymal transition in renal tubular epithelial cells
- (2015) Yanjuan Hou et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Expanding Roles for Lipid Droplets
- (2015) Michael A. Welte CURRENT BIOLOGY
- Metabolic Reprogramming Is Required for Myofibroblast Contractility and Differentiation
- (2015) Karen Bernard et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Deletion of Lkb1 in Renal Tubular Epithelial Cells Leads to CKD by Altering Metabolism
- (2015) S. H. Han et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Metabolic functions of FABPs—mechanisms and therapeutic implications
- (2015) Gökhan S. Hotamisligil et al. Nature Reviews Endocrinology
- CD36 Mediated Fatty Acid-Induced Podocyte Apoptosis via Oxidative Stress
- (2015) Wei Hua et al. PLoS One
- Anti–microRNA-21 oligonucleotides prevent Alport nephropathy progression by stimulating metabolic pathways
- (2014) Ivan G. Gomez et al. JOURNAL OF CLINICAL INVESTIGATION
- TGF- : Duality of Function Between Tumor Prevention and Carcinogenesis
- (2014) D. R. Principe et al. JNCI-Journal of the National Cancer Institute
- Defective fatty acid oxidation in renal tubular epithelial cells has a key role in kidney fibrosis development
- (2014) Hyun Mi Kang et al. NATURE MEDICINE
- Fatty Acid Uptake and Lipid Storage Induced by HIF-1α Contribute to Cell Growth and Survival after Hypoxia-Reoxygenation
- (2014) Karim Bensaad et al. Cell Reports
- Epigenome-Wide Association Study of Fasting Measures of Glucose, Insulin, and HOMA-IR in the Genetics of Lipid Lowering Drugs and Diet Network Study
- (2013) B. Hidalgo et al. DIABETES
- PPARGC1A DNA methylation in subcutaneous adipose tissue in low birth weight subjects — impact of 5days of high-fat overfeeding
- (2013) Linn Gillberg et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Hedgehog-Gli Pathway Activation during Kidney Fibrosis
- (2012) Steven L. Fabian et al. AMERICAN JOURNAL OF PATHOLOGY
- An active metabolite of oltipraz (M2) increases mitochondrial fuel oxidation and inhibits lipogenesis in the liver by dually activating AMPK
- (2012) Tae Hyun Kim et al. BRITISH JOURNAL OF PHARMACOLOGY
- Mast cell activation and degranulation promotes renal fibrosis in experimental unilateral ureteric obstruction
- (2012) Shaun A. Summers et al. KIDNEY INTERNATIONAL
- DNA Methylation and Its Basic Function
- (2012) Lisa D Moore et al. NEUROPSYCHOPHARMACOLOGY
- MicroRNA-21 Promotes Fibrosis of the Kidney by Silencing Metabolic Pathways
- (2012) B. N. Chau et al. Science Translational Medicine
- The peroxisome proliferator-activated receptor-α agonist, BAY PP1, attenuates renal fibrosis in rats
- (2011) Peter Boor et al. KIDNEY INTERNATIONAL
- Cellular and molecular mechanisms of renal fibrosis
- (2011) Youhua Liu Nature Reviews Nephrology
- PPAR-γ Agonists and Their Role in Type 2 Diabetes Mellitus Management
- (2010) Valmore Bermúdez et al. AMERICAN JOURNAL OF THERAPEUTICS
- Renal lipid metabolism and lipotoxicity
- (2010) Ion Alexandru Bobulescu CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION
- Deoxyribonucleic Acid Methylation and Gene Expression ofPPARGC1Ain Human Muscle Is Influenced by High-Fat Overfeeding in a Birth-Weight-Dependent Manner
- (2010) Charlotte Brøns et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Epithelial Notch signaling regulates interstitial fibrosis development in the kidneys of mice and humans
- (2010) Bernhard Bielesz et al. JOURNAL OF CLINICAL INVESTIGATION
- Smad2 Protects against TGF- /Smad3-Mediated Renal Fibrosis
- (2010) X. M. Meng et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Role of adenosine monophosphate-activated protein kinase-p70 ribosomal S6 kinase-1 pathway in repression of liver X receptor-alpha-dependent lipogenic gene induction and hepatic steatosis by a novel class of dithiolethiones
- (2009) Seong Hwan Hwahng et al. HEPATOLOGY
- CD36 Regulates Oxidative Stress and Inflammation in Hypercholesterolemic CKD
- (2009) D. M. Okamura et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Wnt/ -Catenin Signaling Promotes Renal Interstitial Fibrosis
- (2009) W. He et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- PPAR-γ agonist attenuates renal interstitial fibrosis and inflammation through reduction of TGF-β
- (2008) Toru Kawai et al. LABORATORY INVESTIGATION
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationPublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More