MicroRNA-21 Promotes Fibrosis of the Kidney by Silencing Metabolic Pathways

A novel mammalian trans-membrane protein reveals an alternative initiation pathway for autophagy

(2014) Maria I. Vaccaro et al.   Autophagy

Targeting Endothelium-Pericyte Cross Talk by Inhibiting VEGF Receptor Signaling Attenuates Kidney Microvascular Rarefaction and Fibrosis

(2011) Shuei-Liong Lin et al.   AMERICAN JOURNAL OF PATHOLOGY

Pathogenesis of Liver Fibrosis

(2011) Virginia Hernandez-Gea et al.   Annual Review of Pathology-Mechanisms of Disease

Mechanisms of fibrosis: the role of the pericyte

(2011) Claudia Schrimpf et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Smad3-Mediated Upregulation of miR-21 Promotes Renal Fibrosis

(2011) X. Zhong et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

PPAR-γ Ligands Repress TGFβ-Induced Myofibroblast Differentiation by Targeting the PI3K/Akt Pathway: Implications for Therapy of Fibrosis

(2011) Ajit A. Kulkarni et al.   PLoS One

MicroRNA-21 targets peroxisome proliferators-activated receptor-  in an autoregulatory loop to modulate flow-induced endothelial inflammation

(2011) J. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SylArray: a web server for automated detection of miRNA effects from expression data

(2010) N. Bartonicek et al.   BIOINFORMATICS

Modulation of K-Ras-Dependent Lung Tumorigenesis by MicroRNA-21

(2010) Mark E. Hatley et al.   CANCER CELL

Oxidative Stress and Diabetic Complications

(2010) Ferdinando Giacco et al.   CIRCULATION RESEARCH

Stress-dependent cardiac remodeling occurs in the absence of microRNA-21 in mice

(2010) David M. Patrick et al.   JOURNAL OF CLINICAL INVESTIGATION

miR-21 mediates fibrogenic activation of pulmonary fibroblasts and lung fibrosis

(2010) Gang Liu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

OncomiR addiction in an in vivo model of microRNA-21-induced pre-B-cell lymphoma

(2010) Pedro P. Medina et al.   NATURE

Macrophage Wnt7b is critical for kidney repair and regeneration

(2010) S.-L. Lin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of a microRNA signature of renal ischemia reperfusion injury

(2010) J. G. Godwin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA-33 and the SREBP Host Genes Cooperate to Control Cholesterol Homeostasis

(2010) S. H. Najafi-Shoushtari et al.   SCIENCE

Renal Gene and Protein Expression Signatures for Prediction of Kidney Disease Progression

(2009) Wenjun Ju et al.   AMERICAN JOURNAL OF PATHOLOGY

Fate Tracing Reveals the Pericyte and Not Epithelial Origin of Myofibroblasts in Kidney Fibrosis

(2009) Benjamin D. Humphreys et al.   AMERICAN JOURNAL OF PATHOLOGY

The PPAR  Agonist Pioglitazone Ameliorates Aging-Related Progressive Renal Injury

(2009) H.-C. Yang et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Transgenic expression of proximal tubule peroxisome proliferator–activated receptor-α in mice confers protection during acute kidney injury

(2009) Shenyang Li et al.   KIDNEY INTERNATIONAL

c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism

(2009) Ping Gao et al.   NATURE

A three-dimensional view of the molecular machinery of RNA interference

(2009) Martin Jinek et al.   NATURE

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Serum Amyloid P Inhibits Fibrosis Through Fc R-Dependent Monocyte-Macrophage Regulation in Vivo

(2009) A. P. Castano et al.   Science Translational Medicine

Randomized Placebo-Controlled Trial Assessing a Treatment Strategy Consisting of Pravastatin, Vitamin E, and Homocysteine Lowering on Plasma Asymmetric Dimethylarginine Concentration in Mild to Moderate CKD

(2008) Prabath W.B. Nanayakkara et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Kidney injury molecule–1 is a phosphatidylserine receptor that confers a phagocytic phenotype on epithelial cells

(2008) Takaharu Ichimura et al.   JOURNAL OF CLINICAL INVESTIGATION

MicroRNA 21 Promotes Glioma Invasion by Targeting Matrix Metalloproteinase Regulators

(2008) G. Gabriely et al.   MOLECULAR AND CELLULAR BIOLOGY

Vacuole Membrane Protein 1 Is an Endoplasmic Reticulum Protein Required for Organelle Biogenesis, Protein Secretion, and Development

(2008) Javier Calvo-Garrido et al.   MOLECULAR BIOLOGY OF THE CELL

MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts

(2008) Thomas Thum et al.   NATURE

Detecting microRNA binding and siRNA off-target effects from expression data

(2008) Stijn van Dongen et al.   NATURE METHODS

Mpv17l protects against mitochondrial oxidative stress and apoptosis by activation of Omi/HtrA2 protease

(2008) S. Krick et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA