The Clinical Significance of Iron Overload and Iron Metabolism in Myelodysplastic Syndrome and Acute Myeloid Leukemia

Acute Myeloid Leukaemia in Its Niche: the Bone Marrow Microenvironment in Acute Myeloid Leukaemia

(2020) E. E. Ladikou et al.   Current Oncology Reports

Iron Chelation in Transfusion-Dependent Patients With Low- to Intermediate-1–Risk Myelodysplastic Syndromes

(2020) Emanuele Angelucci et al.   ANNALS OF INTERNAL MEDICINE

Aldehyde dehydrogenase 3a2 protects AML cells from oxidative death and the synthetic lethality of ferroptosis inducers

(2020) Rushdia Yusuf et al.   BLOOD

The Effects of Human BDH2 on the Cell Cycle, Differentiation, and Apoptosis and Associations with Leukemia Transformation in Myelodysplastic Syndrome

(2020) Wen-Chi Yang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

FtH-Mediated ROS Dysregulation Promotes CXCL12/CXCR4 Axis Activation and EMT-Like Trans-Differentiation in Erythroleukemia K562 Cells

(2020) Roberta Chirillo et al.   Frontiers in Oncology

The Role of Erastin in Ferroptosis and Its Prospects in Cancer Therapy

(2020) Yuechen Zhao et al.   OncoTargets and Therapy

Identification the prognostic value of glutathione peroxidases expression levels in acute myeloid leukemia

(2020) Jie Wei et al.   Annals of Translational Medicine

Toxic iron species in lower-risk myelodysplastic syndrome patients: course of disease and effects on outcome

(2020) Marlijn Hoeks et al.   LEUKEMIA

Abnormal Ferroptosis in Myelodysplastic Syndrome

(2020) Qi Lv et al.   Frontiers in Oncology

A recycling anti-transferrin receptor-1 monoclonal antibody as an efficient therapy for erythroleukemia through target up-regulation and antibody-dependent cytotoxic effector functions

(2019) Madeline Neiveyans et al.   mAbs

Excessive Reactive Iron Impairs Hematopoiesis by Affecting Both Immature Hematopoietic Cells and Stromal Cells

(2019) Hirokazu Tanaka et al.   Cells

Eltrombopag treatment during induction chemotherapy for acute myeloid leukaemia: a randomised, double-blind, phase 2 study

(2019) Noelle Frey et al.   Lancet Haematology

Chaperone-mediated autophagy is involved in the execution of ferroptosis

(2019) Zheming Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

FDA-approved ferumoxytol displays anti-leukaemia efficacy against cells with low ferroportin levels

(2019) Vicenta Trujillo-Alonso et al.   Nature Nanotechnology

Targeting the hepcidin-ferroportin pathway in anaemia of chronic kidney disease

(2019) Matthew Sheetz et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Efficacy and Feasibility of Sorafenib as a Maintenance Agent After Allogeneic Hematopoietic Stem Cell Transplantation for Fms-like Tyrosine Kinase 3 Mutated Acute Myeloid Leukemia: An Update

(2019) Giorgia Battipaglia et al.   Clinical Lymphoma Myeloma & Leukemia

Low ferroportin expression in AML is correlated with good risk cytogenetics, improved outcomes and increased sensitivity to chemotherapy

(2019) Maura Gasparetto et al.   LEUKEMIA RESEARCH

Impact of red blood cell transfusion dose density on progression-free survival in lower-risk myelodysplastic syndromes patients

(2019) Louise de Swart et al.   HAEMATOLOGICA

Impact of treatment with iron chelation therapy in patients with lower-risk myelodysplastic syndromes participating in the European MDS registry

(2019) Marlijn Hoeks et al.   HAEMATOLOGICA

A variant erythroferrone disrupts iron homeostasis in SF3B1-mutated myelodysplastic syndrome

(2019) Sabrina Bondu et al.   Science Translational Medicine

GDF11 contributes to hepatic HAMP inhibition through SMURF1‐mediated BMP‐SMAD signalling suppression

(2019) Zheng Fang et al.   BRITISH JOURNAL OF HAEMATOLOGY

Iron and leukemia: new insights for future treatments

(2019) Fang Wang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

The Role of Reactive Oxygen Species in Acute Myeloid Leukaemia

(2019) Sillar et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Targeted delivery of DOX by transferrin conjugated DSPE-PEG nanoparticles in leukemia therapy

(2019) Zhigang Fang et al.   International Journal of Polymeric Materials and Polymeric Biomaterials

Ferritin nanovehicle for targeted delivery of cytochrome C to cancer cells

(2019) Alberto Macone et al.   Scientific Reports

Non-transferrin-bound iron and oxidative stress during allogeneic hemopoietic stem cell transplantation in patients with or without iron overload

(2018) Lorena Duca et al.   AMERICAN JOURNAL OF HEMATOLOGY

A storm in the niche: Iron, oxidative stress and haemopoiesis

(2018) Federica Pilo et al.   BLOOD REVIEWS

Clinical Significance of Serum Ferritin at Diagnosis in Patients With Acute Myeloid Leukemia: A YACHT Multicenter Retrospective Study

(2018) Takayoshi Tachibana et al.   Clinical Lymphoma Myeloma & Leukemia

Iron overload impairs normal hematopoietic stem and progenitor cells through reactive oxygen species and shortens survival in myelodysplastic syndrome mice

(2018) Xin Jin et al.   HAEMATOLOGICA

AML: high serum ferritin at initial diagnosis has a negative impact on long-term survival

(2018) Jana Ihlow et al.   LEUKEMIA & LYMPHOMA

Iron chelation therapy in lower IPSS risk myelodysplastic syndromes; which subtypes benefit?

(2018) Shannon A. Wong et al.   LEUKEMIA RESEARCH

Effect of pre-transplantation serum ferritin on outcomes in patients undergoing allogeneic hematopoietic stem cell transplantation

(2018) Zhengwei Yan et al.   MEDICINE

Iron overload promotes mitochondrial fragmentation in mesenchymal stromal cells from myelodysplastic syndrome patients through activation of the AMPK/MFF/Drp1 pathway

(2018) Qingqing Zheng et al.   Cell Death & Disease

Iron overload impairs normal hematopoietic stem and progenitor cells through reactive oxygen species and shortens survival in myelodysplastic syndrome mice

(2018) Xin Jin et al.   HAEMATOLOGICA

Eltrombopag for advanced myelodysplastic syndromes or acute myeloid leukaemia and severe thrombocytopenia (ASPIRE): a randomised, placebo-controlled, phase 2 trial

(2018) Moshe Mittelman et al.   Lancet Haematology

Enhanced labile plasma iron and outcome in acute myeloid leukaemia and myelodysplastic syndrome after allogeneic haemopoietic cell transplantation (ALLIVE): a prospective, multicentre, observational trial

(2018) Martin Wermke et al.   Lancet Haematology

Thrombopoietin receptor–independent stimulation of hematopoietic stem cells by eltrombopag

(2018) Yun-Ruei Kao et al.   Science Translational Medicine

Cancer Treatment through Nanoparticle-Facilitated Fenton Reaction

(2018) Hadi Ranji-Burachaloo et al.   ACS Nano

Effectiveness and Safety of Deferasirox in Thalassemia with Iron Overload: A Meta-Analysis

(2018) Huihong Dou et al.   ACTA HAEMATOLOGICA

Systematic review and meta-analysis of the effect of iron chelation therapy on overall survival and disease progression in patients with lower-risk myelodysplastic syndromes

(2018) Amer M. Zeidan et al.   ANNALS OF HEMATOLOGY

Ferritin heavy/light chain (FTH1/FTL) expression, serum ferritin levels, and their functional as well as prognostic roles in acute myeloid leukemia

(2018) Sarah Bertoli et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

DHA inhibits proliferation and induces ferroptosis of leukemia cells through autophagy dependent degradation of ferritin

(2018) Jing Du et al.   FREE RADICAL BIOLOGY AND MEDICINE

Deferasirox selectively induces cell death in the clinically relevant population of leukemic CD34+CD38– cells through iron chelation, induction of ROS, and inhibition of HIF1α expression

(2018) Saar Shapira et al.   EXPERIMENTAL HEMATOLOGY

Iron overload in myelodysplastic syndromes (MDS)

(2017) Norbert Gattermann   INTERNATIONAL JOURNAL OF HEMATOLOGY

Relation between chelation and clinical outcomes in lower-risk patients with myelodysplastic syndromes: Registry analysis at 5 years

(2017) Roger M. Lyons et al.   LEUKEMIA RESEARCH

Targeting iron metabolism in drug discovery and delivery

(2017) Bart J. Crielaard et al.   NATURE REVIEWS DRUG DISCOVERY

Essential role of FBXL5-mediated cellular iron homeostasis in maintenance of hematopoietic stem cells

(2017) Yoshiharu Muto et al.   Nature Communications

Synergistic inhibitory effects of deferasirox in combination with decitabine on leukemia cell lines SKM-1, THP-1, and K-562

(2017) Nianyi Li et al.   Oncotarget

Iron Handling in Tumor-Associated Macrophages—Is There a New Role for Lipocalin-2?

(2017) Michaela Jung et al.   Frontiers in Immunology

Role of NF-E2 related factor 2 (Nrf2) on chemotherapy resistance in acute myeloid leukemia (AML) and the effect of pharmacological inhibition of Nrf2

(2017) Sreeja Karathedath et al.   PLoS One

Association between Transfusion Status and Overall Survival in Patients with Myelodysplastic Syndromes: A Systematic Literature Review and Meta-Analysis

(2016) Sue Harnan et al.   ACTA HAEMATOLOGICA

Iron overload enhances human mesenchymal stromal cell growth and hampers matrix calcification

(2016) Adriana Borriello et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Transferrin-conjugated polymeric nanomedicine to enhance the anticancer efficacy of edelfosine in acute myeloid leukemia

(2016) Yu Sun et al.   BIOMEDICINE & PHARMACOTHERAPY

Anti-leukaemic effects induced by APR-246 are dependent on induction of oxidative stress and the NFE2L2/HMOX1 axis that can be targeted by PI3K and mTOR inhibitors in acute myeloid leukaemia cells

(2016) Dina Ali et al.   BRITISH JOURNAL OF HAEMATOLOGY

Clinical significance ofTFR2andEPORexpression in bone marrow cells in myelodysplastic syndromes

(2016) Augusta Di Savino et al.   BRITISH JOURNAL OF HAEMATOLOGY

En Route to New Therapeutic Options for Iron Overload Diseases: Matriptase-2 as a Target for Kunitz-Type Inhibitors

(2016) Anna-Madeleine Beckmann et al.   CHEMBIOCHEM

Improving antiproliferative effect of the anticancer drug cytarabine on human promyelocytic leukemia cells by coating on Fe 3 O 4 @SiO 2 nanoparticles

(2016) Nahid Shahabadi et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Leukemia cell infiltration causes defective erythropoiesis partially through MIP-1α/CCL3

(2016) Y Wang et al.   LEUKEMIA

Myelodysplastic syndrome macrophages have aberrant iron storage and heme oxygenase-1 expression

(2016) Grant Nybakken et al.   LEUKEMIA & LYMPHOMA

ROS and ROS-Mediated Cellular Signaling

(2016) Jixiang Zhang et al.   Oxidative Medicine and Cellular Longevity

Cell-permeable iron inhibits vascular endothelial growth factor receptor-2 signaling and tumor angiogenesis

(2016) Devika Kir et al.   Oncotarget

A Polyethylenimine-Containing and Transferrin-Conjugated Lipid Nanoparticle System for Antisense Oligonucleotide Delivery to AML

(2016) Yiming Yuan et al.   Biomed Research International

Transfusion dependency at diagnosis and transfusion intensity during initial chemotherapy are associated with poorer outcomes in adult acute myeloid leukemia

(2015) Giovanna Cannas et al.   ANNALS OF HEMATOLOGY

Mitochondrial ROS metabolism: 10 Years later

(2015) A. Y. Andreyev et al.   BIOCHEMISTRY-MOSCOW

Modulation of iron metabolism by iron chelation regulates intracellular calcium and increases sensitivity to doxorubicin

(2015) Leman Yalcintepe et al.   Bosnian Journal of Basic Medical Sciences

The iron chelator deferasirox affects redox signalling in haematopoietic stem/progenitor cells

(2015) Tiziana Tataranni et al.   BRITISH JOURNAL OF HAEMATOLOGY

Ferritin: A Versatile Building Block for Bionanotechnology

(2015) Günther Jutz et al.   CHEMICAL REVIEWS

H ferritin silencing induces protein misfolding in K562 cells: A Raman analysis

(2015) Fabiana Zolea et al.   FREE RADICAL BIOLOGY AND MEDICINE

Oxidative stress and mitochondrial dysfunction play a role in myelodysplastic syndrome development, diagnosis, and prognosis: A pilot study

(2015) A. C. Gonçalves et al.   FREE RADICAL RESEARCH

Targeting leukemia stem cells in vivo with antagomiR-126 nanoparticles in acute myeloid leukemia

(2015) A M Dorrance et al.   LEUKEMIA

Hyperferritinemia at diagnosis predicts relapse and overall survival in younger AML patients with intermediate-risk cytogenetics

(2015) Delphine Lebon et al.   LEUKEMIA RESEARCH

Ferritinophagy via NCOA4 is required for erythropoiesis and is regulated by iron dependent HERC2-mediated proteolysis

(2015) Joseph D Mancias et al.   eLife

Safety and tolerability of eltrombopag versus placebo for treatment of thrombocytopenia in patients with advanced myelodysplastic syndromes or acute myeloid leukaemia: a multicentre, randomised, placebo-controlled, double-blind, phase 1/2 trial

(2015) Uwe Platzbecker et al.   Lancet Haematology

Effects of Iron Overload on the Bone Marrow Microenvironment in Mice

(2015) Yuchen Zhang et al.   PLoS One

H-Ferritin-Regulated MicroRNAs Modulate Gene Expression in K562 Cells

(2015) Flavia Biamonte et al.   PLoS One

Reactive Oxygen Species Regulate Hematopoietic Stem Cell Self-Renewal, Migration and Development, As Well As Their Bone Marrow Microenvironment

(2014) Aya Ludin et al.   ANTIOXIDANTS & REDOX SIGNALING

Iron Overload in Allogeneic Hematopoietic Cell Transplantation Outcome: A Meta-Analysis

(2014) Philippe Armand et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Deferasirox improves hematopoiesis after allogeneic hematopoietic SCT

(2014) G Visani et al.   BONE MARROW TRANSPLANTATION

Deferasirox for transfusion-dependent patients with myelodysplastic syndromes: safety, efficacy, and beyond (GIMEMA MDS0306 Trial)

(2014) Emanuele Angelucci et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

The bone marrow hematopoietic microenvironment is impaired in iron-overloaded mice

(2014) Hiroshi Okabe et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

Low Intracellular Iron Increases the Stability of Matriptase-2

(2014) Ningning Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The growth-inhibitory and apoptosis-inducing effect of deferoxamine combined with arsenic trioxide on HL-60 xenografts in nude mice

(2014) Runhong Yu et al.   LEUKEMIA RESEARCH

Adequate iron chelation therapy for at least six months improves survival in transfusion-dependent patients with lower risk myelodysplastic syndromes

(2014) Michel Delforge et al.   LEUKEMIA RESEARCH

Serum iron metabolism and erythropoiesis in patients with myelodysplastic syndrome not receiving RBC transfusions

(2014) Rui Cui et al.   LEUKEMIA RESEARCH

Endogenous Siderophore 2,5-Dihydroxybenzoic Acid Deficiency Promotes Anemia and Splenic Iron Overload in Mice

(2014) Z. Liu et al.   MOLECULAR AND CELLULAR BIOLOGY

Identification of erythroferrone as an erythroid regulator of iron metabolism

(2014) Léon Kautz et al.   NATURE GENETICS

Pharmacological inhibition of cystine–glutamate exchange induces endoplasmic reticulum stress and ferroptosis

(2014) Scott J Dixon et al.   eLife

The IRP/IRE system in vivo: insights from mouse models

(2014) Nicole Wilkinson et al.   Frontiers in Pharmacology

Oral ciclopirox olamine displays biological activity in a phase I study in patients with advanced hematologic malignancies

(2013) Mark D. Minden et al.   AMERICAN JOURNAL OF HEMATOLOGY

Overproduction of NOX-derived ROS in AML promotes proliferation and is associated with defective oxidative stress signaling

(2013) P. S. Hole et al.   BLOOD

Free iron catalyzes oxidative damage to hematopoietic cells/mesenchymal stem cellsin vitroand suppresses hematopoiesis in iron overload patients

(2013) Wenyi Lu et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

A phase II trial of sequential ribonucleotide reductase inhibition in aggressive myeloproliferative neoplasms

(2013) J. F. Zeidner et al.   HAEMATOLOGICA

Ferritin H is a novel marker of early erythroid precursors and macrophages

(2013) Wei Wang et al.   HISTOPATHOLOGY

Increased parameters of oxidative stress and its relation to transfusion iron overload in patients with myelodysplastic syndromes

(2013) Geane Felix de Souza et al.   JOURNAL OF CLINICAL PATHOLOGY

Oxidative Stress Levels in Myelodysplastic Syndrome Patients: Their Relationship to Serum Ferritin and Haemoglobin Values

(2013) K Saigo et al.   JOURNAL OF INTERNATIONAL MEDICAL RESEARCH

Significance of CD71 expression by flow cytometry in diagnosis of acute leukemia

(2013) Qian Liu et al.   LEUKEMIA & LYMPHOMA

A comparative study of deferasirox and deferiprone in the treatment of iron overload in patients with myelodysplastic syndromes

(2013) Jaroslav Cermak et al.   LEUKEMIA RESEARCH

Oxidative stress leads to increased mutation frequency in a murine model of myelodysplastic syndrome

(2013) Yang Jo Chung et al.   LEUKEMIA RESEARCH

The role of iron and reactive oxygen species in cell death

(2013) Scott J Dixon et al.   Nature Chemical Biology

Aconitase post-translational modification as a key in linkage between Krebs cycle, iron homeostasis, redox signaling, and metabolism of reactive oxygen species

(2013) Oleh V. Lushchak et al.   REDOX REPORT

DNA Base Damage by Reactive Oxygen Species, Oxidizing Agents, and UV Radiation

(2013) J. Cadet et al.   Cold Spring Harbor Perspectives in Biology

Results from a 1-year, open-label, single arm, multi-center trial evaluating the efficacy and safety of oral Deferasirox in patients diagnosed with low and int-1 risk myelodysplastic syndrome (MDS) and transfusion-dependent iron overload

(2012) F. Nolte et al.   ANNALS OF HEMATOLOGY

STEAP1 is overexpressed in cancers: A promising therapeutic target

(2012) Jerome Moreaux et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Prognostic Impact of Posttransplantation Iron Overload after Allogeneic Stem Cell Transplantation

(2012) Sara C. Meyer et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

An RNAi therapeutic targeting Tmprss6 decreases iron overload in Hfe-/- mice and ameliorates anemia and iron overload in murine  -thalassemia intermedia

(2012) P. J. Schmidt et al.   BLOOD

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

Hematologic responses to deferasirox therapy in transfusion-dependent patients with myelodysplastic syndromes

(2012) N. Gattermann et al.   HAEMATOLOGICA

Deferasirox Reduces Serum Ferritin and Labile Plasma Iron in RBC Transfusion–Dependent Patients With Myelodysplastic Syndrome

(2012) Alan F. List et al.   JOURNAL OF CLINICAL ONCOLOGY

Higherlipocalin 2expression may represent an independent favorable prognostic factor in cytogenetically normal acute myeloid leukemia

(2012) Wen-Chi Yang et al.   LEUKEMIA & LYMPHOMA

Deferasirox exposure induces reactive oxygen species and reduces growth and viability of myelodysplastic hematopoietic progenitors

(2012) Vinod Pullarkat et al.   LEUKEMIA RESEARCH

Targeting etoposide to acute myelogenous leukaemia cells using nanostructured lipid carriers coated with transferrin

(2012) Amir Khajavinia et al.   NANOTECHNOLOGY

Iron Overload in Human Disease

(2012) Robert E. Fleming et al.   NEW ENGLAND JOURNAL OF MEDICINE

Pretransplant iron overload may be associated with increased risk of invasive fungal pneumonia (IFP) in patients that underwent allogeneic hematopoietic stem cell transplantation (alloHSCT)

(2012) Serdar Sivgin et al.   TRANSFUSION AND APHERESIS SCIENCE

Do reactive oxygen species play a role in myeloid leukemias?

(2011) P. S. Hole et al.   BLOOD

Lipocalin 2: A multifaceted modulator of human cancer

(2011) Jiang Yang et al.   CELL CYCLE

Hepcidin expression in patients with acute leukaemia

(2011) Pan-Pan Cheng et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Efficacy And Safety Of Administration Of Oral Iron Chelator Deferiprone In Patients With Early Myelodysplastic Syndrome

(2011) Jaroslav Cermak et al.   HEMOGLOBIN

The effect of iron overload and chelation on erythroid differentiation

(2011) Kazuki Taoka et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

Hepcidin Levels and Their Determinants in Different Types of Myelodysplastic Syndromes

(2011) Valeria Santini et al.   PLoS One

Transfusion intensity, not the cumulative red blood cell transfusion burden, determines the prognosis of patients with myelodysplastic syndrome on chronic transfusion support

(2010) Arturo Pereira et al.   AMERICAN JOURNAL OF HEMATOLOGY

Bone loss caused by iron overload in a murine model: importance of oxidative stress

(2010) J. Tsay et al.   BLOOD

Comparison of 3 Tfr2-deficient murine models suggests distinct functions for Tfr2-  and Tfr2-  isoforms in different tissues

(2010) A. Roetto et al.   BLOOD

Risk factors for fungal pulmonary infections in hematopoietic stem cell transplantation recipients: the role of iron overload

(2010) E Ozyilmaz et al.   BONE MARROW TRANSPLANTATION

Effects of cellular iron deficiency on the formation of vascular endothelial growth factor and angiogenesis. Iron deficiency and angiogenesis

(2010) Jonathan Eckard et al.   Cancer Cell International

Development of Human Single-Chain Antibodies to the Transferrin Receptor that Effectively Antagonize the Growth of Leukemias and Lymphomas

(2010) R. Crepin et al.   CANCER RESEARCH

Two to Tango: Regulation of Mammalian Iron Metabolism

(2010) Matthias W. Hentze et al.   CELL

Changes in parameters of oxidative stress and free iron biomarkers during treatment with deferasirox in iron-overloaded patients with myelodysplastic syndromes

(2010) H. Ghoti et al.   HAEMATOLOGICA

High ferritin levels are associated with hepatosplenic candidiasis in hematopoietic stem cell transplant candidates

(2010) Özlem Güzel Tunçcan et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Targeting iron homeostasis induces cellular differentiation and synergizes with differentiating agents in acute myeloid leukemia

(2010) Celine Callens et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Does iron chelation therapy improve survival in regularly transfused lower risk MDS patients? A multicenter study by the GFM

(2010) Christian Rose et al.   LEUKEMIA RESEARCH

Binding and uptake of H-ferritin are mediated by human transferrin receptor-1

(2010) Li Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Clinical Significance of Serum Hepcidin Levels on Early Infectious Complications in Allogeneic Hematopoietic Stem Cell Transplantation

(2009) Junya Kanda et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Identification of TWSG1 as a second novel erythroid regulator of hepcidin expression in murine and human cells

(2009) T. Tanno et al.   BLOOD

The oral iron chelator deferasirox represses signaling through the mTOR in myeloid leukemia cells by enhancing expression of REDD1

(2009) Junko H. Ohyashiki et al.   CANCER SCIENCE

Regulatory effects of ferritin on angiogenesis

(2009) L. G. Coffman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Iron overload and toxicity: the hidden risk of multiple blood transfusions

(2009) A. Shander et al.   VOX SANGUINIS

INFECTIONS IN THALASSEMIA AND HEMOGLOBINOPATHIES

(2009) Bianca Maria Ricerca et al.   Mediterranean Journal of Hematology and Infectious Diseases

Urinary hepcidin excretion in patients with myelodysplastic syndrome and myelofibrosis

(2008) Asher Winder et al.   BRITISH JOURNAL OF HAEMATOLOGY

Synthesis and anti-cancer activity of covalent conjugates of artemisinin and a transferrin-receptor targeting peptide

(2008) Steve Oh et al.   CANCER LETTERS

The effect of an iron (III) chelator, silybin, on the proliferation and cell cycle of Jurkat cells: A comparison with desferrioxamine

(2008) Marjan Gharagozloo et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Transferrin Receptor-Targeted Lipid Nanoparticles for Delivery of an Antisense Oligodeoxyribonucleotide against Bcl-2

(2008) Xiaojuan Yang et al.   MOLECULAR PHARMACEUTICS

Viral infection and iron metabolism

(2008) Hal Drakesmith et al.   NATURE REVIEWS MICROBIOLOGY

Mechanisms of heme iron absorption: Current questions and controversies

(2008) Adrian R West et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Clinical Relevance of Anemia and Transfusion Iron Overload in Myelodysplastic Syndromes

(2008) M. Cazzola et al.   Hematology-American Society of Hematology Education Program