Epigenetic signatures of Werner syndrome occur early in life and are distinct from normal epigenetic aging processes

Revisiting the genomic hypomethylation hypothesis of aging

(2018) Archana Unnikrishnan et al.   Annals of the New York Academy of Sciences

Genetic and epigenetic changes in clonal descendants of irradiated human fibroblasts

(2018) Julia Flunkert et al.   EXPERIMENTAL CELL RESEARCH

Epigenetic clock for skin and blood cells applied to Hutchinson Gilford Progeria Syndrome and ex vivo studies

(2018) Steve Horvath et al.   Aging-US

Powerful and efficient SNP-set association tests across multiple phenotypes using GWAS summary data

(2018) Bin Guo et al.   BIOINFORMATICS

Characterization of MDPL Fibroblasts Carrying the Recurrent p.Ser605del Mutation in POLD1 Gene

(2018) Chiara Fiorillo et al.   DNA AND CELL BIOLOGY

Hypomethylation of HOXA4 promoter is common in Silver-Russell syndrome and growth restriction and associates with stature in healthy children

(2017) Mari Muurinen et al.   Scientific Reports

Genome-wide DNA methylation analysis in blood cells from patients with Werner syndrome

(2017) T. Guastafierro et al.   Clinical Epigenetics

Epigenetic dysregulation in the developing Down syndrome cortex

(2016) Nady El Hajj et al.   Epigenetics

WRNMutation Update: Mutation Spectrum, Patient Registries, and Translational Prospects

(2016) Koutaro Yokote et al.   HUMAN MUTATION

DNA methylation and healthy human aging

(2015) Meaghan J. Jones et al.   AGING CELL

Alzheimer disease (AD) specific transcription, DNA methylation and splicing in twenty AD associated loci

(2015) Crystal Humphries et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

A Werner syndrome stem cell model unveils heterochromatin alterations as a driver of human aging

(2015) W. Zhang et al.   SCIENCE

Minfi: a flexible and comprehensive Bioconductor package for the analysis of Infinium DNA methylation microarrays

(2014) Martin J. Aryee et al.   BIOINFORMATICS

Ribosomal Proteins and Human Diseases: Pathogenesis, Molecular Mechanisms, and Therapeutic Implications

(2014) Wei Wang et al.   MEDICINAL RESEARCH REVIEWS

Dysregulation of gene expression as a cause of Cockayne syndrome neurological disease

(2014) Yuming Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Accounting for cellular heterogeneity is critical in epigenome-wide association studies

(2014) Andrew E Jaffe et al.   GENOME BIOLOGY

Telomerase Protects Werner Syndrome Lineage-Specific Stem Cells from Premature Aging

(2014) Hoi-Hung Cheung et al.   Stem Cell Reports

Transcriptional Regulation and Its Misregulation in Disease

(2013) Tong Ihn Lee et al.   CELL

An in-frame deletion at the polymerase active site of POLD1 causes a multisystem disorder with lipodystrophy

(2013) Michael N Weedon et al.   NATURE GENETICS

Global Epigenomic Reconfiguration During Mammalian Brain Development

(2013) R. Lister et al.   SCIENCE

DNA methylation age of human tissues and cell types

(2013) Steve Horvath   GENOME BIOLOGY

Comb-p: software for combining, analyzing, grouping and correcting spatially correlated P-values

(2012) B. S. Pedersen et al.   BIOINFORMATICS

Aberrant DNA methylation profiles in the premature aging disorders Hutchinson-Gilford Progeria and Werner syndrome

(2012) Holger Heyn et al.   Epigenetics

The Werner Syndrome Exonuclease Facilitates DNA Degradation and High Fidelity DNA Polymerization by Human DNA Polymerase δ

(2012) Ashwini S. Kamath-Loeb et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functions of DNA methylation: islands, start sites, gene bodies and beyond

(2012) Peter A. Jones   NATURE REVIEWS GENETICS