Transcriptional response of human articular chondrocytes treated with fibronectin fragments: an in vitro model of the osteoarthritis phenotype

Identifying effector molecules, cells, and cytokines of innate immunity in OA

(2020) M.H.J. van den Bosch et al.   OSTEOARTHRITIS AND CARTILAGE

Ferroptosis: past, present and future

(2020) Jie Li et al.   Cell Death & Disease

Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data

(2019) Ioanna Tachmazidou et al.   NATURE GENETICS

A Phase 2 Trial of Lutikizumab, an Anti-Interleukin 1α/β Dual Variable Domain Immunoglobulin, in Knee Osteoarthritis Patients With Synovitis

(2019) Roy M. Fleischmann et al.   Arthritis & Rheumatology

Osteoarthritis

(2019) David J Hunter et al.   LANCET

Long-range enhancer–promoter contacts in gene expression control

(2019) Stefan Schoenfelder et al.   NATURE REVIEWS GENETICS

TGF-β type 2 receptor–mediated modulation of the IL-36 family can be therapeutically targeted in osteoarthritis

(2019) Tieshi Li et al.   Science Translational Medicine

Activation of the P38/CREB/MMP13 axis is associated with osteoarthritis

(2019) Bin Ji et al.   Drug Design Development and Therapy

NF-B Signaling Pathways in Osteoarthritic Cartilage Destruction

(2019) Choi et al.   Cells

SDF-1/CXCR4 axis coordinates crosstalk between subchondral bone and articular cartilage in osteoarthritis pathogenesis

(2019) Han-Jun Qin et al.   BONE

Effect of Intra-Articular Sprifermin vs Placebo on Femorotibial Joint Cartilage Thickness in Patients With Osteoarthritis

(2019) Marc C. Hochberg et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Engineered Cartilage from Human Chondrocytes with Homozygous Knockout of Cell Cycle Inhibitor p21

(2019) Susan D'Costa et al.   TISSUE ENGINEERING PART A

A selective c-Fos/AP-1 inhibitor prevents cartilage destruction and subsequent osteophyte formation

(2018) Hiraku Motomura et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Dynamic 3D chromatin architecture contributes to enhancer specificity and limb morphogenesis

(2018) Bjørt K. Kragesteen et al.   NATURE GENETICS

Fibroblast growth factor 18 exerts anti-osteoarthritic effects through PI3K-AKT signaling and mitochondrial fusion and fission

(2018) Xudong Yao et al.   PHARMACOLOGICAL RESEARCH

Coral: Clear and Customizable Visualization of Human Kinome Data

(2018) Kathleen S. Metz et al.   Cell Systems

Etanercept in patients with inflammatory hand osteoarthritis (EHOA): a multicentre, randomised, double-blind, placebo-controlled trial

(2018) Margreet Kloppenburg et al.   ANNALS OF THE RHEUMATIC DISEASES

Heavy-tailed prior distributions for sequence count data: removing the noise and preserving large differences

(2018) Anqi Zhu et al.   BIOINFORMATICS

Pro-inflammatory cytokines: The link between obesity and osteoarthritis

(2018) Tiantian Wang et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Articular chondrocytes isolated from the knee and ankle joints of human tissue donors demonstrate similar redox-regulated MAP kinase and Akt signaling

(2018) J.A. Collins et al.   OSTEOARTHRITIS AND CARTILAGE

Cell-type-specific gene expression patterns in the knee cartilage in an osteoarthritis rat model

(2017) Michal Korostynski et al.   FUNCTIONAL & INTEGRATIVE GENOMICS

Salmon provides fast and bias-aware quantification of transcript expression

(2017) Rob Patro et al.   NATURE METHODS

Wnt5a induces catabolic signaling and matrix metalloproteinase production in human articular chondrocytes

(2017) G. Huang et al.   OSTEOARTHRITIS AND CARTILAGE

The integrin–collagen connection – a glue for tissue repair?

(2016) Cédric Zeltz et al.   JOURNAL OF CELL SCIENCE

Epigenetic Regulation of Early- and Late-Response Genes in Acute Pancreatitis

(2016) Juan Sandoval et al.   JOURNAL OF IMMUNOLOGY

The IL-1β/AP-1/miR-30a/ADAMTS-5 axis regulates cartilage matrix degradation in human osteoarthritis

(2016) Quanbo Ji et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

In vitro models for the study of osteoarthritis

(2016) Craig I. Johnson et al.   VETERINARY JOURNAL

SoxC transcription factors in skeletogenesis and cartilage differentiation

(2015) V. Lefebvre et al.   OSTEOARTHRITIS AND CARTILAGE

Insights into osteoarthritis progression revealed by analyses of both knee tibiofemoral compartments

(2015) C.-H. Chou et al.   OSTEOARTHRITIS AND CARTILAGE

BAPX-1/NKX-3.2 Acts as a Chondrocyte Hypertrophy Molecular Switch in Osteoarthritis

(2015) Marjolein M. J. Caron et al.   Arthritis & Rheumatology

Cysteine-Mediated Redox Regulation of Cell Signaling in Chondrocytes Stimulated With Fibronectin Fragments

(2015) Scott T. Wood et al.   Arthritis & Rheumatology

The Role of Inflammatory and Anti-Inflammatory Cytokines in the Pathogenesis of Osteoarthritis

(2014) Piotr Wojdasiewicz et al.   MEDIATORS OF INFLAMMATION

Genes Involved in the Osteoarthritis Process Identified through Genome Wide Expression Analysis in Articular Cartilage; the RAAK Study

(2014) Yolande F. M. Ramos et al.   PLoS One

The Response of Secondary Genes to Lipopolysaccharides in Macrophages Depends on Histone Deacetylase and Phosphorylation of C/EBP 

(2013) N. Serrat et al.   JOURNAL OF IMMUNOLOGY

Alterations to the remote control of Shh gene expression cause congenital abnormalities

(2013) R. E. Hill et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

GREM1, FRZB and DKK1 mRNA levels correlate with osteoarthritis and are regulated by osteoarthritis-associated factors

(2013) Jeroen CH Leijten et al.   ARTHRITIS RESEARCH & THERAPY

Gene Expression Pattern of Cells From Inflamed and Normal Areas of Osteoarthritis Synovial Membrane

(2013) Cécile Lambert et al.   Arthritis & Rheumatology

Osteoarthritis: A disease of the joint as an organ

(2012) Richard F. Loeser et al.   ARTHRITIS AND RHEUMATISM

Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study

(2012)   LANCET

The long-range interaction landscape of gene promoters

(2012) Amartya Sanyal et al.   NATURE

Synovial inflammation, immune cells and their cytokines in osteoarthritis: a review

(2012) B.J.E. de Lange-Brokaar et al.   OSTEOARTHRITIS AND CARTILAGE

Direct assessment of articular cartilage and underlying subchondral bone reveals a progressive gene expression change in human osteoarthritic knees

(2012) C.-H. Chou et al.   OSTEOARTHRITIS AND CARTILAGE

Plasma proteins present in osteoarthritic synovial fluid can stimulate cytokine production via Toll-like receptor 4

(2012) Dong Sohn et al.   ARTHRITIS RESEARCH & THERAPY

Dynamic long-range chromatin interactions controlMybproto-oncogene transcription during erythroid development

(2011) Ralph Stadhouders et al.   EMBO JOURNAL

ADAMTS-4 and ADAMTS-5: Key enzymes in osteoarthritis

(2011) Priyanka Verma et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Mitochondrial reactive oxygen species drive proinflammatory cytokine production: Figure 1.

(2011) Edwina Naik et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The role of mitochondria in osteoarthritis

(2011) Francisco J. Blanco et al.   Nature Reviews Rheumatology

Hereditary hemochromatosis is characterized by a clinically definable arthropathy that correlates with iron load

(2010) G. J. Carroll et al.   ARTHRITIS AND RHEUMATISM

Selective Transcription in Response to an Inflammatory Stimulus

(2010) Stephen T. Smale   CELL

Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities

(2010) Sven Heinz et al.   MOLECULAR CELL

Bone Morphogenetic Proteins and articular cartilage

(2010) P.M. van der Kraan et al.   OSTEOARTHRITIS AND CARTILAGE

Genome-wide expression profiling reveals new candidate genes associated with osteoarthritis

(2010) C. Karlsson et al.   OSTEOARTHRITIS AND CARTILAGE

The Interleukin 1β Pathway in the Pathogenesis of Osteoarthritis

(2008) Massoud Daheshia et al.   JOURNAL OF RHEUMATOLOGY

SOX Gene Expression in Human Osteoarthritic Cartilage

(2008) Jochen Haag et al.   PATHOBIOLOGY