NF-B Signaling Pathways in Osteoarthritic Cartilage Destruction

Cortistatin binds to TNF-α receptors and protects against osteoarthritis

(2019) Yunpeng Zhao et al.   EBioMedicine

Excessive mechanical loading promotes osteoarthritis through the gremlin-1–NF-κB pathway

(2019) Song Ho Chang et al.   Nature Communications

Osteoarthritis- a systematic review of long-term safety implications for osteoarthritis of the knee

(2019) Jonathon Charlesworth et al.   BMC MUSCULOSKELETAL DISORDERS

TGF-β type 2 receptor–mediated modulation of the IL-36 family can be therapeutically targeted in osteoarthritis

(2019) Tieshi Li et al.   Science Translational Medicine

Stress-activated miR-204 governs senescent phenotypes of chondrocytes to promote osteoarthritis development

(2019) Donghyun Kang et al.   Science Translational Medicine

Phenotypic instability of chondrocytes in osteoarthritis: on a path to hypertrophy

(2018) Purva Singh et al.   Annals of the New York Academy of Sciences

MiR-149 suppresses the inflammatory response of chondrocytes in osteoarthritis by down-regulating the activation of TAK1/NF-κB

(2018) Qiaojie Chen et al.   BIOMEDICINE & PHARMACOTHERAPY

Ghrelin protects against osteoarthritis through interplay with Akt and NF-κB signaling pathways

(2018) Ruize Qu et al.   FASEB JOURNAL

Mithramycin A Alleviates Osteoarthritic Cartilage Destruction by Inhibiting HIF-2α Expression

(2018) Moon-Chang Choi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Therapeutics in Osteoarthritis Based on an Understanding of Its Molecular Pathogenesis

(2018) Ju-Ryoung Kim et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Modulation of Matrix Metabolism By ATP-Citrate Lyase In Articular Chondrocytes

(2018) Liang-Yu Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Osteoarthritis year in review 2017: genetics and epigenetics

(2018) M.J. Peffers et al.   OSTEOARTHRITIS AND CARTILAGE

Epigenetics in osteoarthritis: Potential of HDAC inhibitors as therapeutics

(2018) Nazir M. Khan et al.   PHARMACOLOGICAL RESEARCH

Elf3 Contributes to Cartilage Degradation in vivo in a Surgical Model of Post-Traumatic Osteoarthritis

(2018) Elisabeth B. Wondimu et al.   Scientific Reports

Loss of periostin ameliorates adipose tissue inflammation and fibrosis in vivo

(2018) Fumiko Nakazeki et al.   Scientific Reports

Alleviation of Murine Osteoarthritis by Cartilage-Specific Deletion of IkappaBzeta

(2018) Moon-Chang Choi et al.   Arthritis & Rheumatology

Intraperitoneal injection of the SIRT1 activator SRT1720 attenuates the progression of experimental osteoarthritis in mice

(2018) K. Nishida et al.   Bone & Joint Research

ACY-1215 exhibits anti-inflammatory and chondroprotective effects in human osteoarthritis chondrocytes via inhibition of STAT3 and NF-κB signaling pathways

(2018) Chao Cheng et al.   BIOMEDICINE & PHARMACOTHERAPY

MicroRNA‑93 inhibits chondrocyte apoptosis and inflammation in osteoarthritis by targeting the TLR4/NF‑κB signaling pathway

(2018) Yanjie Ding et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Intra-articular treatment options for knee osteoarthritis

(2018) Ian A. Jones et al.   Nature Reviews Rheumatology

Reciprocal inhibition of YAP/TAZ and NF-κB regulates osteoarthritic cartilage degradation

(2018) Yujie Deng et al.   Nature Communications

Intra-articular administration of IκBα kinase inhibitor suppresses mouse knee osteoarthritis via downregulation of the NF-κB/HIF-2α axis

(2018) Yasutaka Murahashi et al.   Scientific Reports

Necrostatin-1 Attenuates Trauma-Induced Mouse Osteoarthritis and IL-1β Induced Apoptosis via HMGB1/TLR4/SDF-1 in Primary Mouse Chondrocytes

(2018) Shuang Liang et al.   Frontiers in Pharmacology

Adipokine Contribution to the Pathogenesis of Osteoarthritis

(2017) Daniel Azamar-Llamas et al.   MEDIATORS OF INFLAMMATION

Resistin promotes CCL4 expression through toll-like receptor-4 and activation of the p38-MAPK and NF-κB signaling pathways: implications for intervertebral disc degeneration

(2017) Z. Li et al.   OSTEOARTHRITIS AND CARTILAGE

Cartilage-specific deletion of Alk5 gene results in a progressive osteoarthritis-like phenotype in mice

(2017) Q. Wang et al.   OSTEOARTHRITIS AND CARTILAGE

miR-146a facilitates osteoarthritis by regulating cartilage homeostasis via targeting Camk2d and Ppp3r2

(2017) Xudong Zhang et al.   Cell Death & Disease

Osteopontin: Relation between Adipose Tissue and Bone Homeostasis

(2017) Carolina De Fusco et al.   Stem Cells International

Systemic inhibition of IL-6/Stat3 signalling protects against experimental osteoarthritis

(2016) Augustin Latourte et al.   ANNALS OF THE RHEUMATIC DISEASES

MicroRNA-26a-5p regulates the expression of inducible nitric oxide synthase via activation of NF-κB pathway in human osteoarthritis chondrocytes

(2016) Zafar Rasheed et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Overexpression of HMGB1 A-box reduced IL-1β-induced MMP expression and the production of inflammatory mediators in human chondrocytes

(2016) Yahui Fu et al.   EXPERIMENTAL CELL RESEARCH

The NF-κB family: Key players during embryonic development and HSC emergence

(2016) Raquel Espín-Palazón et al.   EXPERIMENTAL HEMATOLOGY

Blocking of the P2X7 receptor inhibits the activation of the MMP-13 and NF-κB pathways in the cartilage tissue of rats with osteoarthritis

(2016) Hongbo Hu et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Roles of microRNA and signaling pathway in osteoarthritis pathogenesis

(2016) Bin Xu et al.   Journal of Zhejiang University-SCIENCE B

MicroRNA-9 regulates the development of knee osteoarthritis through the NF-kappaB1 pathway in chondrocytes

(2016) Ronghe Gu et al.   MEDICINE

Periostin action in bone

(2016) Nicolas Bonnet et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Reduced miR-26a and miR-26b expression contributes to the pathogenesis of osteoarthritis via the promotion of p65 translocation

(2016) Xuefeng Yin et al.   Molecular Medicine Reports

MicroRNA-320 regulates matrix metalloproteinase-13 expression in chondrogenesis and interleukin-1β-induced chondrocyte responses

(2016) F. Meng et al.   OSTEOARTHRITIS AND CARTILAGE

Suppression of NF-κB activity via nanoparticle-based siRNA delivery alters early cartilage responses to injury

(2016) Huimin Yan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biphasic regulation of chondrocytes by Rela through induction of anti-apoptotic and catabolic target genes

(2016) Hiroshi Kobayashi et al.   Nature Communications

Osteopontin Promotes Expression of Matrix Metalloproteinase 13 through NF-κB Signaling in Osteoarthritis

(2016) Yusheng Li et al.   Biomed Research International

Crosstalk between Wnt/β-Catenin and NF-κB Signaling Pathway during Inflammation

(2016) Bin Ma et al.   Frontiers in Immunology

Inhibition of transforming growth factor β-activated kinase 1 prevents inflammation-related cartilage degradation in osteoarthritis

(2016) Jin Cheng et al.   Scientific Reports

Expression and pathological effects of periostin in human osteoarthritis cartilage

(2015) Ryota Chijimatsu et al.   BMC MUSCULOSKELETAL DISORDERS

KPNA2 interacts with P65 to modulate catabolic events in osteoarthritis

(2015) Ran Tao et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

MicroRNA-146a reduces IL-1 dependent inflammatory responses in the intervertebral disc

(2015) Su-Xi Gu et al.   GENE

Intra-articular delivery of anti-Hif-2α siRNA by chondrocyte-homing nanoparticles to prevent cartilage degeneration in arthritic mice

(2015) Y Pi et al.   GENE THERAPY

Sam68 Promotes NF-κB Activation and Apoptosis Signaling in Articular Chondrocytes during Osteoarthritis

(2015) Libin Xu et al.   INFLAMMATION RESEARCH

Chondrocyte Apoptosis in the Pathogenesis of Osteoarthritis

(2015) Hyun Hwang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

­­­­­Insulin-Like Growth Factor II (IGF-II) Inhibits IL-1β-Induced Cartilage Matrix Loss and Promotes Cartilage Integrity in Experimental Osteoarthritis

(2015) Tomoya Uchimura et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

SERPINE2 Inhibits IL-1α-Induced MMP-13 Expression in Human Chondrocytes: Involvement of ERK/NF-κB/AP-1 Pathways

(2015) Anna Santoro et al.   PLoS One

Histone deacetylase inhibition activates Nrf2 and protects against osteoarthritis

(2015) Dawei Cai et al.   ARTHRITIS RESEARCH & THERAPY

Lentivirus-induced knockdown of LRP1 induces osteoarthritic-like effects and increases susceptibility to apoptosis in chondrocytes via the nuclear factor-κB pathway

(2015) ERPING YANG et al.   Experimental and Therapeutic Medicine

Osteopontin inhibits HIF-2α mRNA expression in osteoarthritic chondrocytes

(2015) CHAO CHENG et al.   Experimental and Therapeutic Medicine

MiR-210 inhibits NF-κB signaling pathway by targeting DR6 in osteoarthritis

(2015) Dawei Zhang et al.   Scientific Reports

IL-36α: a novel cytokine involved in the catabolic and inflammatory response in chondrocytes

(2015) Javier Conde et al.   Scientific Reports

Overexpression of Sirtuin 6 suppresses cellular senescence and NF-κB mediated inflammatory responses in osteoarthritis development

(2015) Yaosen Wu et al.   Scientific Reports

Chondrocyte hypertrophy in skeletal development, growth, and disease

(2014) Margaret Man-Ger Sun et al.   BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS

Leptin induces ADAMTS-4, ADAMTS-5, and ADAMTS-9 genes expression by mitogen-activated protein kinases and NF-ĸB signaling pathways in human chondrocytes

(2014) Kursat Oguz Yaykasli et al.   CELL BIOLOGY INTERNATIONAL

Role of miR-146a in human chondrocyte apoptosis in response to mechanical pressure injury in vitro

(2014) LEI JIN et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

The Role of Inflammatory and Anti-Inflammatory Cytokines in the Pathogenesis of Osteoarthritis

(2014) Piotr Wojdasiewicz et al.   MEDIATORS OF INFLAMMATION

Remodelling the extracellular matrix in development and disease

(2014) Caroline Bonnans et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mouse models of osteoarthritis: modelling risk factors and assessing outcomes

(2014) Hang Fang et al.   Nature Reviews Rheumatology

The individual and socioeconomic impact of osteoarthritis

(2014) David J. Hunter et al.   Nature Reviews Rheumatology

Osteoarthritis, obesity and weight loss: evidence, hypotheses and horizons - a scoping review

(2014) H. Bliddal et al.   Obesity Reviews

Association of osteopontin with osteoarthritis

(2014) Chao Cheng et al.   RHEUMATOLOGY INTERNATIONAL

Expression and function of visfatin (Nampt), an adipokine-enzyme involved in inflammatory pathways of osteoarthritis

(2014) Marie-Charlotte Laiguillon et al.   ARTHRITIS RESEARCH & THERAPY

Osteopontin: A novel regulator at the cross roads of inflammation, obesity and diabetes

(2014) Florian Kahles et al.   Molecular Metabolism

Disruption of Sirt1 in chondrocytes causes accelerated progression of osteoarthritis under mechanical stress and during ageing in mice

(2013) Tokio Matsuzaki et al.   ANNALS OF THE RHEUMATIC DISEASES

NAMPT (visfatin), a direct target of hypoxia-inducible factor-2α, is an essential catabolic regulator of osteoarthritis

(2013) Siyoung Yang et al.   ANNALS OF THE RHEUMATIC DISEASES

Deletion of the Transforming Growth Factor β Receptor Type II Gene in Articular Chondrocytes Leads to a Progressive Osteoarthritis-like Phenotype in Mice

(2013) Jie Shen et al.   ARTHRITIS AND RHEUMATISM

I B-  controls the constitutive NF- B target gene network and survival of ABC DLBCL

(2013) H. Nogai et al.   BLOOD

Vorinostat, a HDAC inhibitor, showed anti-osteoarthritic activities through inhibition of iNOS and MMP expression, p38 and ERK phosphorylation and blocking NF-κB nuclear translocation

(2013) Hui-ming Zhong et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

The NF-κB signalling pathway in osteoarthritis

(2013) Stella Rigoglou et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

T Cell Factor 4 Is a Pro-catabolic and Apoptotic Factor in Human Articular Chondrocytes by Potentiating Nuclear Factor κB Signaling

(2013) Bin Ma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transcriptional Induction of ADAMTS5 Protein by Nuclear Factor-κB (NF-κB) Family Member RelA/p65 in Chondrocytes during Osteoarthritis Development

(2013) Hiroshi Kobayashi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Aggrecanase and Aggrecan Degradation in Osteoarthritis: A Review

(2013) K Huang et al.   JOURNAL OF INTERNATIONAL MEDICAL RESEARCH

MicroRNA-558 regulates the expression of cyclooxygenase-2 and IL-1β-induced catabolic effects in human articular chondrocytes

(2013) S.J. Park et al.   OSTEOARTHRITIS AND CARTILAGE

The role of high mobility group box chromosomal protein 1 in rheumatoid arthritis

(2013) Yu Chen et al.   RHEUMATOLOGY

KPNB1,XPO7and IPO8 Mediate the Translocation ofNF-κB/p65 into the Nucleus

(2013) Peizhou Liang et al.   TRAFFIC

Cytokine signaling-1 suppressor is inducible by IL-1beta and inhibits the catabolic effects of IL-1beta in chondrocytes: its implication in the paradoxical joint-protective role of IL-1beta

(2013) Yong Choi et al.   ARTHRITIS RESEARCH & THERAPY

Sam68 modulates the promoter specificity of NF-κB and mediates expression of CD25 in activated T cells

(2013) Kai Fu et al.   Nature Communications

The Age-Related Changes in Cartilage and Osteoarthritis

(2013) YongPing Li et al.   Biomed Research International

The novel cytokine interleukin-36α is expressed in psoriatic and rheumatoid arthritis synovium

(2012) Silke Frey et al.   ANNALS OF THE RHEUMATIC DISEASES

Loss of methylation in CpG sites in the NF-κB enhancer elements of inducible nitric oxide synthase is responsible for gene induction in human articular chondrocytes

(2012) María C. de Andrés et al.   ARTHRITIS AND RHEUMATISM

The role of synovitis in osteoarthritis pathogenesis

(2012) Carla R. Scanzello et al.   BONE

Regulation of Chondrocytic Gene Expression by Biomechanical Signals

(2012) Thomas J. Knobloch et al.   CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION

NF- B, the first quarter-century: remarkable progress and outstanding questions

(2012) M. S. Hayden et al.   GENES & DEVELOPMENT

MiRNA-140 is a negative feedback regulator of MMP-13 in IL-1β-stimulated human articular chondrocyte C28/I2 cells

(2012) Zu-jian Liang et al.   INFLAMMATION RESEARCH

The overexpression of SIRT1 inhibited osteoarthritic gene expression changes induced by interleukin-1β in human chondrocytes

(2012) Takehiko Matsushita et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Bone remodelling in osteoarthritis

(2012) David B. Burr et al.   Nature Reviews Rheumatology

Macro view of microRNA function in osteoarthritis

(2012) Shigeru Miyaki et al.   Nature Reviews Rheumatology

Synovial inflammation, immune cells and their cytokines in osteoarthritis: a review

(2012) B.J.E. de Lange-Brokaar et al.   OSTEOARTHRITIS AND CARTILAGE

SIRT1, a class III histone deacetylase, regulates TNF-α-induced inflammation in human chondrocytes

(2012) M.-H. Moon et al.   OSTEOARTHRITIS AND CARTILAGE

Osteoarthritis as an inflammatory disease (osteoarthritis is not osteoarthrosis!)

(2012) F. Berenbaum   OSTEOARTHRITIS AND CARTILAGE

SIRT1 Activators Suppress Inflammatory Responses through Promotion of p65 Deacetylation and Inhibition of NF-κB Activity

(2012) Hongying Yang et al.   PLoS One

miR-146a, an IL-1β responsive miRNA, induces vascular endothelial growth factor and chondrocyte apoptosis by targeting Smad4

(2012) Jing Li et al.   ARTHRITIS RESEARCH & THERAPY

Hypoxia-inducible factor-2α regulates Fas-mediated chondrocyte apoptosis during osteoarthritic cartilage destruction

(2011) J-H Ryu et al.   CELL DEATH AND DIFFERENTIATION

Inflammation in osteoarthritis

(2011) Mary B. Goldring et al.   CURRENT OPINION IN RHEUMATOLOGY

MicroRNA-146a is linked to pain-related pathophysiology of osteoarthritis

(2011) Xin Li et al.   GENE

C/EBPβ and RUNX2 cooperate to degrade cartilage with MMP-13 as the target and HIF-2α as the inducer in chondrocytes

(2011) Makoto Hirata et al.   HUMAN MOLECULAR GENETICS

Chondrocyte apoptosis: a cause or consequence of osteoarthritis?

(2011) Zaitunnatakhin ZAMLI et al.   International Journal of Rheumatic Diseases

E74-like Factor 3 (ELF3) Impacts on Matrix Metalloproteinase 13 (MMP13) Transcriptional Control in Articular Chondrocytes under Proinflammatory Stress

(2011) Miguel Otero et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Adiponectin increases MMP-3 expression in human chondrocytes through adipor1 signaling pathway

(2011) Kwok-Man Tong et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Sam68 Is Required for Both NF-κB Activation and Apoptosis Signaling by the TNF Receptor

(2011) Parameswaran Ramakrishnan et al.   MOLECULAR CELL

Chondrocyte hypertrophy and osteoarthritis: role in initiation and progression of cartilage degeneration?

(2011) P.M. van der Kraan et al.   OSTEOARTHRITIS AND CARTILAGE

Anabolic/Catabolic Balance in Pathogenesis of Osteoarthritis: Identifying Molecular Targets

(2011) Michael B. Mueller et al.   PM&R

MicroRNA-27b regulates the expression of matrix metalloproteinase 13 in human osteoarthritis chondrocytes

(2010) Nahid Akhtar et al.   ARTHRITIS AND RHEUMATISM

Why is osteoarthritis an age-related disease?

(2010) A. Shane Anderson et al.   BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY

A single NFκB system for both canonical and non-canonical signaling

(2010) Vincent Feng-Sheng Shih et al.   CELL RESEARCH

Posttranslational modifications of NF-κB: Another layer of regulation for NF-κB signaling pathway

(2010) Bo Huang et al.   CELLULAR SIGNALLING

NF-κB Signaling: Multiple Angles to Target OA

(2010) Kenneth B. Marcu et al.   CURRENT DRUG TARGETS

Disease Modifying Osteoarthritis Drugs: Facing Development Challenges and Choosing Molecular Targets

(2010) Marie-Pierre Hellio Le Graverand-Gastineau   CURRENT DRUG TARGETS

SIRT2 regulates NF- B-dependent gene expression through deacetylation of p65 Lys310

(2010) K. M. Rothgiesser et al.   JOURNAL OF CELL SCIENCE

Alleviation of osteoarthritis by Trichostatin A, a histone deacetylase inhibitor, in experimental osteoarthritis

(2010) Wei-Ping Chen et al.   MOLECULAR BIOLOGY REPORTS

IκBζ regulates TH17 development by cooperating with ROR nuclear receptors

(2010) Kazuo Okamoto et al.   NATURE

Transcriptional regulation of endochondral ossification by HIF-2α during skeletal growth and osteoarthritis development

(2010) Taku Saito et al.   NATURE MEDICINE

Hypoxia-inducible factor-2α is a catabolic regulator of osteoarthritic cartilage destruction

(2010) Siyoung Yang et al.   NATURE MEDICINE

The role of the cartilage matrix in osteoarthritis

(2010) Dick Heinegård et al.   Nature Reviews Rheumatology

Role of proinflammatory cytokines in the pathophysiology of osteoarthritis

(2010) Mohit Kapoor et al.   Nature Reviews Rheumatology

High mobility group box 1 potentiates the pro-inflammatory effects of interleukin-1β in osteoarthritic synoviocytes

(2010) Isabel García-Arnandis et al.   ARTHRITIS RESEARCH & THERAPY

Hypertrophic differentiation of chondrocytes in osteoarthritis: the developmental aspect of degenerative joint disorders

(2010) Rita Dreier   ARTHRITIS RESEARCH & THERAPY

STAT3, p38 MAPK, and NF-κB Drive Unopposed Monocyte-Dependent Fibroblast MMP-1 Secretion in Tuberculosis

(2009) Cecilia M. O'Kane et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Accelerated development of aging-associated and instability-induced osteoarthritis in osteopontin-deficient mice

(2009) Yuichiro Matsui et al.   ARTHRITIS AND RHEUMATISM

Matrix metalloproteinase 13–deficient mice are resistant to osteoarthritic cartilage erosion but not chondrocyte hypertrophy or osteophyte development

(2009) C. B. Little et al.   ARTHRITIS AND RHEUMATISM

Expression of MicroRNA-146a in osteoarthritis cartilage

(2009) Keiichiro Yamasaki et al.   ARTHRITIS AND RHEUMATISM

SIRT6 Links Histone H3 Lysine 9 Deacetylation to NF-κB-Dependent Gene Expression and Organismal Life Span

(2009) Tiara L.A. Kawahara et al.   CELL

Leptin Enhances Synthesis of Proinflammatory Mediators in Human Osteoarthritic Cartilage—Mediator Role of NO in Leptin-InducedPGE2, IL-6, and IL-8 Production

(2009) Katriina Vuolteenaho et al.   MEDIATORS OF INFLAMMATION

Elevated osteopontin level of synovial fluid and articular cartilage is associated with disease severity in knee osteoarthritis patients

(2009) S.G. Gao et al.   OSTEOARTHRITIS AND CARTILAGE

Biomechanical Thresholds Regulate Inflammation through the NF-κB Pathway: Experiments and Modeling

(2009) Jin Nam et al.   PLoS One

Cartilage homeostasis in health and rheumatic diseases

(2009) Mary B Goldring et al.   ARTHRITIS RESEARCH & THERAPY

The NF- B Family of Transcription Factors and Its Regulation

(2009) A. Oeckinghaus et al.   Cold Spring Harbor Perspectives in Biology

Differential expression of GADD45β in normal and osteoarthritic cartilage: Potential role in homeostasis of articular chondrocytes

(2008) Kosei Ijiri et al.   ARTHRITIS AND RHEUMATISM

Shared Principles in NF-κB Signaling

(2008) Matthew S. Hayden et al.   CELL

Regulation of epithelium-specific Ets-like factors ESE-1 and ESE-3 in airway epithelial cells: potential roles in airway inflammation

(2008) Jing Wu et al.   CELL RESEARCH

The IKK-NF-κB pathway: a source for novel molecular drug targets in pain therapy?

(2008) Ellen Niederberger et al.   FASEB JOURNAL

p38/NF‐kB‐dependent expression of COX‐2 during differentiation and inflammatory response of chondrocytes

(2008) Valentina Ulivi et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Osteoarthritis and nitric oxide

(2008) Steven B. Abramson   OSTEOARTHRITIS AND CARTILAGE

Molecular network of cartilage homeostasis and osteoarthritis

(2007) Megumi Hashimoto et al.   MEDICINAL RESEARCH REVIEWS

Suppression of early experimental osteoarthritis by in vivo delivery of the adenoviral vector-mediated NF-κBp65-specific siRNA

(2007) L.X. Chen et al.   OSTEOARTHRITIS AND CARTILAGE